Publication Information

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'can': [156], 'reach': [157], '30%': [158], 'open': [160, 413, 1102], 'fractures.1': [161], 'Until': [162], 'recently,': [163], 'amputation': [164], 'recurrence': [166], 'rates': [167], 'remained': [168], 'high.2,4': [169], 'With': [170], 'the': [171, 221, 247, 343, 346, 369, 372, 375, 384, 467, 497, 551, 639, 680, 866, 872, 878, 884, 889, 897, 903, 926, 932, 941, 961, 964, 977, 982, 987], 'publication': [172], 'international': [174, 614, 641, 847], 'consensus': [175, 609, 642], 'documents,4,5': [176], 'an': [177, 613, 846, 956], 'evidence-based': [178], 'overview': [179], 'diagnosis': [181], 'management': [183, 318, 478, 706], 'has': [184, 320], 'been': [185, 321, 911], 'provided,': [186], 'which': [187, 975], 'should': [188, 324, 418, 451, 1099], 'improve': [189], 'treatment': [190, 578, 839], 'outcomes.PathologyThe': [191], 'pathology': [192], 'multifactorial;': [196], 'bacterial': [197], 'fracture': [200, 356, 443, 523, 548], 'instability': [201, 231], 'are': [202, 220, 381, 445, 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'administration': [417], 'not': [419], 'exceed': [420], '24': [421], 'hours': [422, 431], 'Gustilo-Anderson': [424, 433], 'types': [425], 'I': [426], 'II': [428], '72': [430], 'III': [435], 'fractures.5,7': [436], 'Early': [437], 'debridement,': [438], 'management,': [440], 'stable': [442], 'cornerstones': [446], 'management.5Follow-up': [448], 'planned': [453], 'collaboration': [455], 'team,': [459], 'minimum': [462], '12': [464], 'months': [465], 'after': [466, 522, 547, 1008], 'cessation': [468], 'surgical': [470, 526], 'therapy.11Future': [473], 'perspectives': [474], 'prevention': [476], 'include:': [481], 'antimicrobial': [482, 507], 'coated': [483], 'implants;': [484], 'osteoinductive': [485], 'antibiotic-loaded': [486], 'biomaterials;': [487], 'bacteriophage': [489], 'enzybiotic': [491], 'therapy.': [492], 'All': [493], 'these': [494], 'therapies': [495], 'consider': [496], 'global': [498], 'threat': [499], 'resistance': [502], 'target': [504], 'mechanisms': [505], 'tolerance': [508], 'as': [510], 'biofilm': [511], 'formation.1References1.': [512], 'Metsemakers': [513, 537, 598, 626, 830], 'WJ,': [514, 599], 'Kuehl': [515, 696], 'R,': [516, 697, 724], 'Moriarty': [517, 659, 700, 948], 'TF,': [518, 660, 701], 'et': [519, 574, 604, 630, 727, 805, 836, 952, 1187], 'al.': [520, 575, 605, 631, 728, 806, 837, 953], 'Infection': [521, 546], 'fixation:': [524], 'Current': [525], 'microbiological': [528], 'concepts.': [529], 'Injury.': [530, 560, 617, 685], '2018;49(3):511–522.': [531], 'Crossref,': [532, 562, 593, 619, 653, 687, 714, 753, 794, 825, 855], 'Medline,': [533, 563, 594, 620, 688, 715, 754, 795, 826, 856], 'ISI,': [534, 564, 595, 621, 654, 689, 716, 755, 796, 827, 857], 'Google': [535, 565, 596, 622, 655, 690, 717, 756, 797, 828, 858], 'Scholar2.': [536], 'W-.': [538], 'J,': [539], 'Smeets': [540], 'B,': [541], 'Nijs': [542], 'S,': [543, 763], 'Hoekstra': [544], 'H.': [545], 'tibia:': [552], 'Analysis': [553], 'healthcare': [555], 'utilization': [556], 'related': [558, 921], 'costs.': [559], '2017;48(6):1204–1210.': [561], 'Scholar3.': [566], 'Bezstarosti': [567], 'H,': [568], 'Van': [569], 'Lieshout': [570], 'EMM,': [571], 'Voskamp': [572], 'LW,': [573], 'Insights': [576], 'into': [577], 'outcome': [580], 'fracture-related': [582, 678, 708, 842], 'infection:': [583, 607, 679, 843], 'systematic': [585], 'literature': [586], 'review.': [587], 'Arch': [588, 850], 'Orthop': [589, 851], 'Surg.': [591, 853], '2019;139(1):61–72.': [592], 'Scholar4.': [597], 'Morgenstern': [600, 663, 694, 832], 'M,': [601, 664, 693, 695, 802, 833], 'McNally': [602], 'MA,': [603], 'Fracture-related': [606], 'definition': [611], 'from': [612, 819, 845, 917, 1005], 'expert': [615, 848], 'group.': [616, 849], '2018;49(3):505–510.': [618], 'Scholar5.': [623], 'Obremskey': [624, 702], 'WT,': [625], 'W-J,': [627, 831], 'Schlatterer': [628], 'DR,': [629], 'orthopaedic': [635], 'trauma:': [636], 'Assessment': [637], '2018': [640], 'meeting': [643], 'musculoskeletal': [645], 'infection.': [646, 709], 'J': [647, 748], 'Surg': [650], 'Am.': [651], '2020;102-A(10):e44.': [652], 'Scholar6.': [656], 'Foster': [657], 'AL,': [658], 'Zalavras': [661], 'C,': [662], 'Jaiprakash': [665], 'A,': [666], 'Crawford': [667], 'R.': [668], 'influence': [670], 'biomechanical': [672], 'bone': [675, 742, 1041, 1080, 1143], 'healing': [676], 'legacy': [681], 'Stephan': [683], 'Perren.': [684], '2020;52(1):43–52.': [686], 'Scholar7.': [691], 'Depypere': [692], 'Senneville': [698, 834], 'E,': [699, 765, 835], 'WT.': [703], 'Pathogenesis': [704], 'Clin': [710], 'Microbiol': [711], 'Infect.': [712], '2020;26(5):572–578.': [713], 'Scholar8.': [718], 'de': [719], 'Mesy': [720], 'Bentley': [721], 'KL,': [722], 'Trombetta': [723], 'Nishitani': [725], 'K,': [726], 'Evidence': [729], 'staphylococcus': [731], 'aureus': [732, 774, 785, 811], 'deformation,': [733], 'proliferation,': [734], 'migration': [736], 'canaliculi': [738], 'live': [740], 'cortical': [741], 'murine': [744], 'models': [745], 'osteomyelitis.': [747], 'Miner': [750], 'Res.': [751], '2017;32(5):985–990.': [752], 'Scholar9.': [757], 'Mohamed': [758], 'W,': [759], 'Sommer': [760], 'U,': [761, 767], 'Sethi': [762], 'Domann': [764], 'Thormann': [766], 'Schütz': [768], 'I.': [769], 'Intracellular': [770], 'proliferation': [771, 787], 'S.': [773, 784], 'osteoblasts': [776], 'effects': [778], 'rifampicin': [780], 'gentamicin': [782], 'survival.': [789], 'Eur': [790], 'Cell': [791], 'Mater.': [792], '2014;28:258–268.': [793], 'Scholar10.': [798], 'Hofstee': [799], 'MI,': [800], 'Riool': [801], 'Terjajevs': [803], 'I,': [804], 'Three-Dimensional': [807], 'Vitro': [809], 'Staphylococcus': [810], 'Abscess': [812], 'Communities': [813], 'Display': [814], 'Antibiotic': [815], 'Tolerance': [816], 'Protection': [818], 'Neutrophil': [820], 'Clearance.': [821], 'Infect': [822], 'Immun.': [823], '2020;88(11):e00293-20.': [824], 'Scholar11.': [829], 'General': [838], 'principles': [840], 'Recommendations': [844], '2020;140(8):1013–1027.': [854], 'ScholarAuthor': [859], 'contributionsS.': [860], 'Baertl:': [861], 'Designed,': [862], 'created,': [863], 'revised': [865, 871, 877, 883, 896, 902], 'infographic.W-J.': [867], 'Metsemakers:': [868], 'Designed': [869, 875, 881, 900], 'infographic.M.': [873], 'Morgenstern:': [874], 'infographic.V.': [879], 'Alt:': [880], 'infographic.R.': [885], 'G.': [886], 'Richards:': [887], 'Revised': [888], 'infographic.T.': [890], 'F.': [891, 947], 'Moriarty:': [892], 'Conceptualized,': [893], 'designed,': [894], 'infographic.K.': [898], 'Young:': [899], 'infographic.Funding': [904], 'statementNo': [905], 'benefits': [906], 'any': [908], 'form': [909], 'have': [910, 1104], 'received': [912, 916], 'will': [914], 'commercial': [919], 'party': [920], 'directly': [922], 'indirectly': [924], 'subject': [927], 'article.AcknowledgementsWe': [930], 'acknowledge': [931], 'contribution': [933], 'Artist': [936], 'Louise': [937], 'Hinman': [938], 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[1011], 'Xu,': [1012], 'Yalan': [1013], 'Zeng,': [1014], 'Xiao': [1015], 'Yang,': [1016, 1022], 'Guangfu': [1017], 'Liu,': [1018], 'Taiyong': [1019], 'Lv,': [1020], 'Hongbin': [1021], 'Fei': [1023], 'Jiang,': [1024], 'Yue': [1025], 'Chen22': [1026], 'June': [1027, 1182], '2022': [1028, 1070, 1132], '|': [1029, 1071, 1133, 1161], 'Research,': [1033, 1075, 1137, 1165], 'Vol.': [1034, 1076, 1138, 1166, 1170], '11,': [1035, 1077, 1139], '6Fracture-related': [1037], 'osteoporotic': [1040], 'causes': [1042], 'severe': [1044], 'further': [1047], 'delays': [1048], 'healingJie': [1049], 'Li,': [1050], 'Ronald': [1051], 'Man': [1052], 'Yeung': [1053], 'Wong,': [1054], 'Yik': [1055], 'Lok': [1056], 'Chung,': [1057], 'Sharon': [1058], 'Shui': [1059], 'Yee': [1060], 'Leung,': [1061], 'Simon': [1062], 'Kwoon-Ho': [1063], 'Chow,': [1064], 'Margaret': [1065], 'Ip,': [1066], 'Wing-Hoi': [1067], 'Cheung1': [1068], 'February': [1069, 1131], '2Tibial': [1079], 'concentrations': [1083], 'following': 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