PAM: diverse roles in neuroendocrine cells, cardiomyocytes, and green algae

Name: Work Video:
Duration: 3 min 30 s
Nils Bäck; Richard E. Mains; Betty Eipper
{'id': 'https://openalex.org/W3164118779', 'doi': 'https://doi.org/10.1111/febs.16049', 'title': 'PAM: diverse roles in neuroendocrine cells, cardiomyocytes, and green algae', 'display_name': 'PAM: diverse roles in neuroendocrine cells, cardiomyocytes, and green algae', 'publication_year': 2021, 'publication_date': '2021-06-05', 'ids': {'openalex': 'https://openalex.org/W3164118779', 'doi': 'https://doi.org/10.1111/febs.16049', 'mag': '3164118779', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34089560'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/febs.16049', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.16049', 'source': {'id': 'https://openalex.org/S37672443', 'display_name': 'FEBS Journal', 'issn_l': '1742-464X', 'issn': ['1742-464X', '1742-4658'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.16049', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087036071', 'display_name': 'Nils Bäck', 'orcid': 'https://orcid.org/0000-0001-9992-3726'}, 'institutions': [{'id': 'https://openalex.org/I133731052', 'display_name': 'University of Helsinki', 'ror': 'https://ror.org/040af2s02', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I133731052']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Nils Bäck', 'raw_affiliation_strings': ['Department of Anatomy, University of Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy, University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I133731052']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011997610', 'display_name': 'Richard E. Mains', 'orcid': 'https://orcid.org/0000-0003-1154-1331'}, 'institutions': [{'id': 'https://openalex.org/I75929689', 'display_name': 'UConn Health', 'ror': 'https://ror.org/02kzs4y22', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I75929689']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard E. Mains', 'raw_affiliation_strings': ['Department of Neuroscience, UConn Health, Farmington, CT, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Neuroscience, UConn Health, Farmington, CT, USA', 'institution_ids': ['https://openalex.org/I75929689']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5015706491', 'display_name': 'Betty Eipper', 'orcid': 'https://orcid.org/0000-0003-1171-5557'}, 'institutions': [{'id': 'https://openalex.org/I75929689', 'display_name': 'UConn Health', 'ror': 'https://ror.org/02kzs4y22', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I75929689']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Betty A. Eipper', 'raw_affiliation_strings': ['Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, USA', 'institution_ids': ['https://openalex.org/I75929689']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5015706491'], 'corresponding_institution_ids': ['https://openalex.org/I75929689'], 'apc_list': {'value': 4580, 'currency': 'USD', 'value_usd': 4580, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.373, 'has_fulltext': False, 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.399194, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '289', 'issue': '15', 'first_page': '4470', 'last_page': '4496'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10155', 'display_name': 'Nitric Oxide and Endothelin Effects', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10155', 'display_name': 'Nitric Oxide and Endothelin Effects', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12236', 'display_name': 'Photoreceptor and optogenetics research', 'score': 0.9954, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9898, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chlamydomonas-reinhardtii', 'display_name': 'Chlamydomonas reinhardtii', 'score': 0.8178362}, {'id': 'https://openalex.org/keywords/secretory-vesicle', 'display_name': 'Secretory Vesicle', 'score': 0.6561737}, {'id': 'https://openalex.org/keywords/enteroendocrine-cell', 'display_name': 'Enteroendocrine cell', 'score': 0.55684936}], 'concepts': [{'id': 'https://openalex.org/C2777727519', 'wikidata': 'https://www.wikidata.org/wiki/Q291827', 'display_name': 'Chlamydomonas reinhardtii', 'level': 4, 'score': 0.8178362}, {'id': 'https://openalex.org/C2909863526', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretory Vesicle', 'level': 4, 'score': 0.6561737}, {'id': 'https://openalex.org/C49039625', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretion', 'level': 2, 'score': 0.5894099}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5822415}, {'id': 'https://openalex.org/C103395026', 'wikidata': 'https://www.wikidata.org/wiki/Q5380231', 'display_name': 'Enteroendocrine cell', 'level': 4, 'score': 0.55684936}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.55167824}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5450511}, {'id': 'https://openalex.org/C6492254', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretory pathway', 'level': 4, 'score': 0.52853364}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.43362403}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.3262027}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.28432253}, {'id': 'https://openalex.org/C175969161', 'wikidata': 'https://www.wikidata.org/wiki/Q323426', 'display_name': 'Exocytosis', 'level': 3, 'score': 0.26105213}, {'id': 'https://openalex.org/C119062480', 'wikidata': 'https://www.wikidata.org/wiki/Q83181', 'display_name': 'Golgi apparatus', 'level': 3, 'score': 0.2585104}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.08282149}, {'id': 'https://openalex.org/C46699223', 'wikidata': 'https://www.wikidata.org/wiki/Q11078', 'display_name': 'Endocrine system', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016825', 'descriptor_name': 'Chlamydomonas reinhardtii', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006899', 'descriptor_name': 'Mixed Function Oxygenases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D055099', 'descriptor_name': 'Neuroendocrine Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016825', 'descriptor_name': 'Chlamydomonas reinhardtii', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006899', 'descriptor_name': 'Mixed Function Oxygenases', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D055099', 'descriptor_name': 'Neuroendocrine Cells', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010802', 'descriptor_name': 'Phylogeny', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/febs.16049', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.16049', 'source': {'id': 'https://openalex.org/S37672443', 'display_name': 'FEBS Journal', 'issn_l': '1742-464X', 'issn': ['1742-464X', '1742-4658'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34089560', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/febs.16049', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.16049', 'source': {'id': 'https://openalex.org/S37672443', 'display_name': 'FEBS Journal', 'issn_l': '1742-464X', 'issn': ['1742-464X', '1742-4658'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/15', 'display_name': 'Life on land', 'score': 0.41}], 'grants': [{'funder': 'https://openalex.org/F4320311816', 'funder_display_name': 'Finska Läkaresällskapet', 'award_id': None}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'GM‐125606'}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'DK‐032948'}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'DK‐032949'}], 'datasets': [], 'versions': [], 'referenced_works_count': 190, 'referenced_works': ['https://openalex.org/W149632730', 'https://openalex.org/W1510399117', 'https://openalex.org/W1571114305', 'https://openalex.org/W1581159824', 'https://openalex.org/W1586989529', 'https://openalex.org/W1589276697', 'https://openalex.org/W1922584555', 'https://openalex.org/W1967131697', 'https://openalex.org/W1970713347', 'https://openalex.org/W1970870627', 'https://openalex.org/W1972337182', 'https://openalex.org/W1972786933', 'https://openalex.org/W1974131176', 'https://openalex.org/W1977579237', 'https://openalex.org/W1977603129', 'https://openalex.org/W1979168227', 'https://openalex.org/W1979348380', 'https://openalex.org/W1981916517', 'https://openalex.org/W1983159731', 'https://openalex.org/W1987256329', 'https://openalex.org/W1990488427', 'https://openalex.org/W1990713759', 'https://openalex.org/W1991824197', 'https://openalex.org/W1995699883', 'https://openalex.org/W1996562607', 'https://openalex.org/W2000331857', 'https://openalex.org/W2001473326', 'https://openalex.org/W2005196094', 'https://openalex.org/W2005384449', 'https://openalex.org/W2006149815', 'https://openalex.org/W2006655885', 'https://openalex.org/W2008146810', 'https://openalex.org/W2010285313', 'https://openalex.org/W2011330079', 'https://openalex.org/W2011632934', 'https://openalex.org/W2013264450', 'https://openalex.org/W2013655231', 'https://openalex.org/W2015397446', 'https://openalex.org/W2016671569', 'https://openalex.org/W2017750045', 'https://openalex.org/W2020044636', 'https://openalex.org/W2021305630', 'https://openalex.org/W2028159086', 'https://openalex.org/W2030330371', 'https://openalex.org/W2031342255', 'https://openalex.org/W2032089157', 'https://openalex.org/W2034790110', 'https://openalex.org/W2038107872', 'https://openalex.org/W2038744035', 'https://openalex.org/W2041162855', 'https://openalex.org/W2048466832', 'https://openalex.org/W2048998123', 'https://openalex.org/W2051473647', 'https://openalex.org/W2062644850', 'https://openalex.org/W2063103311', 'https://openalex.org/W2063229901', 'https://openalex.org/W2068309907', 'https://openalex.org/W2068749469', 'https://openalex.org/W2069630707', 'https://openalex.org/W2069790849', 'https://openalex.org/W2070341655', 'https://openalex.org/W2071965463', 'https://openalex.org/W2072292928', 'https://openalex.org/W2072704725', 'https://openalex.org/W2072896958', 'https://openalex.org/W2075783751', 'https://openalex.org/W2079107219', 'https://openalex.org/W2083171893', 'https://openalex.org/W2084946181', 'https://openalex.org/W2085832613', 'https://openalex.org/W2085860025', 'https://openalex.org/W2085876171', 'https://openalex.org/W2086873619', 'https://openalex.org/W2088425060', 'https://openalex.org/W2089741235', 'https://openalex.org/W2094945284', 'https://openalex.org/W2095351176', 'https://openalex.org/W2098094939', 'https://openalex.org/W2098117914', 'https://openalex.org/W2098273883', 'https://openalex.org/W2099486375', 'https://openalex.org/W2099635718', 'https://openalex.org/W2106011107', 'https://openalex.org/W2106205024', 'https://openalex.org/W2108825548', 'https://openalex.org/W2109380817', 'https://openalex.org/W2113476159', 'https://openalex.org/W2122238523', 'https://openalex.org/W2122850009', 'https://openalex.org/W2124657728', 'https://openalex.org/W2127427521', 'https://openalex.org/W2129774902', 'https://openalex.org/W2130634514', 'https://openalex.org/W2138769722', 'https://openalex.org/W2143358122', 'https://openalex.org/W2148351021', 'https://openalex.org/W2148646831', 'https://openalex.org/W2150992807', 'https://openalex.org/W2151129660', 'https://openalex.org/W2153798770', 'https://openalex.org/W2154203178', 'https://openalex.org/W2155177646', 'https://openalex.org/W2156602181', 'https://openalex.org/W2159607115', 'https://openalex.org/W2160074417', 'https://openalex.org/W2161767563', 'https://openalex.org/W2163610365', 'https://openalex.org/W2166247822', 'https://openalex.org/W2170171321', 'https://openalex.org/W2212848802', 'https://openalex.org/W2263913345', 'https://openalex.org/W2278362303', 'https://openalex.org/W2293178987', 'https://openalex.org/W2298520537', 'https://openalex.org/W2302038089', 'https://openalex.org/W2322161127', 'https://openalex.org/W2413353318', 'https://openalex.org/W2473094948', 'https://openalex.org/W2500974730', 'https://openalex.org/W2519463765', 'https://openalex.org/W2536013550', 'https://openalex.org/W2553997083', 'https://openalex.org/W2566427422', 'https://openalex.org/W2595720112', 'https://openalex.org/W2602475549', 'https://openalex.org/W2615414462', 'https://openalex.org/W2626837753', 'https://openalex.org/W2728447508', 'https://openalex.org/W2750063112', 'https://openalex.org/W2750674195', 'https://openalex.org/W2763157882', 'https://openalex.org/W2766752424', 'https://openalex.org/W2770281322', 'https://openalex.org/W2779083329', 'https://openalex.org/W2781875842', 'https://openalex.org/W2782755660', 'https://openalex.org/W2783941908', 'https://openalex.org/W2786268145', 'https://openalex.org/W2790791668', 'https://openalex.org/W2793873144', 'https://openalex.org/W2795280840', 'https://openalex.org/W2803220159', 'https://openalex.org/W2805030993', 'https://openalex.org/W2808808201', 'https://openalex.org/W2884197940', 'https://openalex.org/W2885544593', 'https://openalex.org/W2886128958', 'https://openalex.org/W2888357771', 'https://openalex.org/W2888559607', 'https://openalex.org/W2889378253', 'https://openalex.org/W2897506399', 'https://openalex.org/W2905589155', 'https://openalex.org/W2911835872', 'https://openalex.org/W2917152053', 'https://openalex.org/W2921963917', 'https://openalex.org/W2934275657', 'https://openalex.org/W2938132638', 'https://openalex.org/W2942608650', 'https://openalex.org/W2946855586', 'https://openalex.org/W2949339075', 'https://openalex.org/W2950869104', 'https://openalex.org/W2952696651', 'https://openalex.org/W2953189140', 'https://openalex.org/W2963653689', 'https://openalex.org/W2967614896', 'https://openalex.org/W2970132750', 'https://openalex.org/W2972316856', 'https://openalex.org/W2973105130', 'https://openalex.org/W2982577166', 'https://openalex.org/W2994551450', 'https://openalex.org/W2995589956', 'https://openalex.org/W2998605097', 'https://openalex.org/W3001456307', 'https://openalex.org/W3006087096', 'https://openalex.org/W3006599272', 'https://openalex.org/W3014557508', 'https://openalex.org/W3023305400', 'https://openalex.org/W3026566441', 'https://openalex.org/W3040582145', 'https://openalex.org/W3041242507', 'https://openalex.org/W3052397347', 'https://openalex.org/W3083704026', 'https://openalex.org/W3085872455', 'https://openalex.org/W3086820607', 'https://openalex.org/W3152848834', 'https://openalex.org/W4231408219', 'https://openalex.org/W4241709086', 'https://openalex.org/W4243291830', 'https://openalex.org/W4255020332', 'https://openalex.org/W576933762'], 'related_works': ['https://openalex.org/W2753518337', 'https://openalex.org/W2523520718', 'https://openalex.org/W2381607572', 'https://openalex.org/W2346510371', 'https://openalex.org/W2138593684', 'https://openalex.org/W2006943139', 'https://openalex.org/W1979137878', 'https://openalex.org/W1967140524', 'https://openalex.org/W1533741620', 'https://openalex.org/W12626829'], 'abstract_inverted_index': {'Our': [0], 'understanding': [1], 'of': [2, 22, 28, 46, 50, 73, 92, 142, 155, 162, 188, 199, 209, 216], 'the': [3, 13, 20, 56, 64, 68, 79, 90, 124, 140, 153, 159, 179, 185, 197], 'ways': [4, 229], 'in': [5, 12, 32, 38, 83, 89, 158, 178, 201, 219, 230, 240], 'which': [6, 29, 231], 'peptides': [7, 94], 'are': [8, 194], 'used': [9], 'for': [10, 36, 128], 'communication': [11], 'nervous': [14], 'and': [15, 25, 75, 105, 119, 132, 139, 147, 152, 190, 204, 207, 224, 243], 'endocrine': [16], 'systems': [17], 'began': [18], 'with': [19, 114], 'identification': [21], 'oxytocin,': [23], 'vasopressin,': [24], 'insulin,': [26], 'each': [27, 45], 'is': [30, 59, 95], 'stored': [31, 82], 'electron-dense': [33], 'granules,': [34, 170], 'ready': [35], 'release': [37], 'response': [39], 'to': [40, 70, 236], 'an': [41, 103], 'appropriate': [42], 'stimulus.': [43], 'For': [44], 'these': [47], 'peptides,': [48], 'entry': [49], 'its': [51, 115, 210], 'newly': [52], 'synthesized': [53], 'precursor': [54, 69], 'into': [55], 'ER': [57], 'lumen': [58], 'followed': [60], 'by': [61, 98], 'transport': [62], 'through': [63], 'secretory': [65, 111, 169], 'pathway,': [66], 'exposing': [67], 'a': [71, 165, 173], 'sequence': [72], 'environments': [74], 'enzymes': [76], 'that': [77, 109, 172], 'produce': [78], 'bioactive': [80], 'products': [81, 212], 'mature': [84], 'granules.': [85], 'A': [86, 214], 'final': [87], 'step': [88], 'biosynthesis': [91], 'many': [93, 134], 'C-terminal': [96], 'amidation': [97], 'peptidylglycine': [99], 'α-amidating': [100], 'monooxygenase': [101], '(PAM),': [102], 'ascorbate-': [104], 'copper-dependent': [106], 'membrane': [107], 'enzyme': [108, 175], 'enters': [110], 'granules': [112], 'along': [113], 'soluble': [116], 'substrates.': [117], 'Biochemical': [118], 'cell': [120, 244], 'biological': [121], 'studies': [122, 151], 'elucidated': [123], 'highly': [125], 'conserved': [126], 'mechanism': [127], 'amidated': [129, 211], 'peptide': [130], 'production': [131], 'raised': [133], 'questions': [135], 'about': [136], 'PAM': [137, 143, 157, 193, 200, 217, 235], 'trafficking': [138, 198, 233], 'effects': [141], 'on': [144], 'cytoskeletal': [145], 'organization': [146], 'gene': [148], 'expression.': [149], 'Phylogenetic': [150], 'discovery': [154], 'active': [156], 'ciliary': [160], 'membranes': [161], 'Chlamydomonas': [163], 'reinhardtii,': [164], 'green': [166], 'alga': [167], 'lacking': [168], 'suggested': [171], 'PAM-like': [174], 'was': [176], 'present': [177], 'last': [180], 'eukaryotic': [181], 'common': [182], 'ancestor.': [183], 'While': [184], 'catalytic': [186], 'features': [187], 'human': [189], 'C.': [191, 202, 225], 'reinhardtii': [192, 203, 226], 'strikingly': [195], 'similar,': [196], 'neuroendocrine': [205, 220], 'cells': [206], 'secretion': [208], 'differ.': [213], 'comparison': [215], 'function': [218], 'cells,': [221], 'atrial': [222], 'myocytes,': [223], 'reveals': [227], 'multiple': [228], 'altered': [232], 'allows': [234], 'accomplish': [237], 'different': [238, 241], 'tasks': [239], 'species': [242], 'types.': [245]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3164118779', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}], 'updated_date': '2024-12-20T18:17:21.117136', 'created_date': '2021-06-07'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
