Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3159813479', 'doi': 'https://doi.org/10.1111/febs.15898', 'title': 'Caspase‐9 acts as a regulator of necroptotic cell death', 'display_name': 'Caspase‐9 acts as a regulator of necroptotic cell death', 'publication_year': 2021, 'publication_date': '2021-05-08', 'ids': {'openalex': 'https://openalex.org/W3159813479', 'doi': 'https://doi.org/10.1111/febs.15898', 'mag': '3159813479', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33899329'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/febs.15898', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.15898', 'source': {'id': 'https://openalex.org/S37672443', 'display_name': 'FEBS Journal', 'issn_l': '1742-464X', 'issn': ['1742-464X', '1742-4658'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.15898', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025520088', 'display_name': 'Tamás Molnár', 'orcid': 'https://orcid.org/0000-0002-5720-0447'}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Tamás Molnár', 'raw_affiliation_strings': ['Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'Doctoral School of Molecular Cellular and Immune Biology University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Doctoral School of Molecular Cellular and Immune Biology University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}, {'raw_affiliation_string': 'Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042485976', 'display_name': 'Petra Pallagi', 'orcid': 'https://orcid.org/0000-0001-8906-0840'}, 'institutions': [{'id': 'https://openalex.org/I227486990', 'display_name': 'University of Szeged', 'ror': 'https://ror.org/01pnej532', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I227486990']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Petra Pallagi', 'raw_affiliation_strings': ['First Department of Medicine University of Szeged Szeged Hungary', 'HAS-USZ Momentum Epithelial Cell Signalling and Secretion Research Group University of Szeged Szeged Hungary'], 'affiliations': [{'raw_affiliation_string': 'HAS-USZ Momentum Epithelial Cell Signalling and Secretion Research Group University of Szeged Szeged Hungary', 'institution_ids': ['https://openalex.org/I227486990']}, {'raw_affiliation_string': 'First Department of Medicine University of Szeged Szeged Hungary', 'institution_ids': ['https://openalex.org/I227486990']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016307875', 'display_name': 'Bálint Tél', 'orcid': 'https://orcid.org/0000-0003-2066-6494'}, 'institutions': [{'id': 'https://openalex.org/I227486990', 'display_name': 'University of Szeged', 'ror': 'https://ror.org/01pnej532', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I227486990']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Bálint Tél', 'raw_affiliation_strings': ['First Department of Medicine University of Szeged Szeged Hungary', 'HAS-USZ Momentum Epithelial Cell Signalling and Secretion Research Group University of Szeged Szeged Hungary'], 'affiliations': [{'raw_affiliation_string': 'HAS-USZ Momentum Epithelial Cell Signalling and Secretion Research Group University of Szeged Szeged Hungary', 'institution_ids': ['https://openalex.org/I227486990']}, {'raw_affiliation_string': 'First Department of Medicine University of Szeged Szeged Hungary', 'institution_ids': ['https://openalex.org/I227486990']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082505630', 'display_name': 'Róbert Király', 'orcid': 'https://orcid.org/0000-0002-1606-3132'}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Róbert Király', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology Faculty of Medicine University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087265496', 'display_name': 'Eszter Csoma', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Eszter Csoma', 'raw_affiliation_strings': ['Department of Medical Microbiology Faculty of Medicine University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Microbiology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040663379', 'display_name': 'Viktória Jenei', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Viktória Jenei', 'raw_affiliation_strings': ['Department of Immunology Faculty of Medicine University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039054439', 'display_name': 'Zsófia Varga', 'orcid': 'https://orcid.org/0009-0002-3051-4953'}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Zsófia Varga', 'raw_affiliation_strings': ['Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'Doctoral School of Molecular Cellular and Immune Biology University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Doctoral School of Molecular Cellular and Immune Biology University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}, {'raw_affiliation_string': 'Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074365621', 'display_name': 'Péter Gogolák', 'orcid': 'https://orcid.org/0000-0001-9411-9587'}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Péter Gogolák', 'raw_affiliation_strings': ['Department of Immunology Faculty of Medicine University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063423811', 'display_name': 'Anne‐Odile Hueber', 'orcid': 'https://orcid.org/0000-0003-3816-2446'}, 'institutions': [{'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I201841394', 'display_name': "Université Côte d'Azur", 'ror': 'https://ror.org/019tgvf94', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I201841394']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Anne Odile Hueber', 'raw_affiliation_strings': ["CNRS Inserm iBV Université Côte d'Azur Nice France"], 'affiliations': [{'raw_affiliation_string': "CNRS Inserm iBV Université Côte d'Azur Nice France", 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I201841394', 'https://openalex.org/I1294671590']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061089265', 'display_name': 'Zoltán Máté', 'orcid': 'https://orcid.org/0009-0001-7141-7116'}, 'institutions': [{'id': 'https://openalex.org/I4210106880', 'display_name': 'HUN-REN Institute of Experimental Medicine', 'ror': 'https://ror.org/01jsgmp44', 'country_code': 'HU', 'type': 'facility', 'lineage': ['https://openalex.org/I4210106880', 'https://openalex.org/I7597260']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Zoltán Máté', 'raw_affiliation_strings': ['Medical Gene Technology Unit Institute of Experimental Medicine Budapest Hungary'], 'affiliations': [{'raw_affiliation_string': 'Medical Gene Technology Unit Institute of Experimental Medicine Budapest Hungary', 'institution_ids': ['https://openalex.org/I4210106880']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103014310', 'display_name': 'Ferenc Erdélyi', 'orcid': 'https://orcid.org/0000-0002-9564-8955'}, 'institutions': [{'id': 'https://openalex.org/I4210106880', 'display_name': 'HUN-REN Institute of Experimental Medicine', 'ror': 'https://ror.org/01jsgmp44', 'country_code': 'HU', 'type': 'facility', 'lineage': ['https://openalex.org/I4210106880', 'https://openalex.org/I7597260']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Ferenc Erdélyi', 'raw_affiliation_strings': ['Medical Gene Technology Unit Institute of Experimental Medicine Budapest Hungary'], 'affiliations': [{'raw_affiliation_string': 'Medical Gene Technology Unit Institute of Experimental Medicine Budapest Hungary', 'institution_ids': ['https://openalex.org/I4210106880']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049960571', 'display_name': 'Gábor Szabó', 'orcid': 'https://orcid.org/0000-0001-5438-5151'}, 'institutions': [{'id': 'https://openalex.org/I4210106880', 'display_name': 'HUN-REN Institute of Experimental Medicine', 'ror': 'https://ror.org/01jsgmp44', 'country_code': 'HU', 'type': 'facility', 'lineage': ['https://openalex.org/I4210106880', 'https://openalex.org/I7597260']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Gábor Szabó', 'raw_affiliation_strings': ['Medical Gene Technology Unit Institute of Experimental Medicine Budapest Hungary'], 'affiliations': [{'raw_affiliation_string': 'Medical Gene Technology Unit Institute of Experimental Medicine Budapest Hungary', 'institution_ids': ['https://openalex.org/I4210106880']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019717640', 'display_name': 'Aladár Pettkó‐Szandtner', 'orcid': 'https://orcid.org/0000-0002-9145-4686'}, 'institutions': [{'id': 'https://openalex.org/I2800351701', 'display_name': 'HUN-REN Szegedi Biológiai Kutatóközpont', 'ror': 'https://ror.org/016gb1631', 'country_code': 'HU', 'type': 'facility', 'lineage': ['https://openalex.org/I2800351701', 'https://openalex.org/I7597260']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Aladár Pettkó‐Szandtner', 'raw_affiliation_strings': ['Laboratory of Proteomics Research Biological Research Centre Szeged Hungary'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Proteomics Research Biological Research Centre Szeged Hungary', 'institution_ids': ['https://openalex.org/I2800351701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090781260', 'display_name': 'Attila Bácsi', 'orcid': 'https://orcid.org/0000-0002-2311-2975'}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Attila Bácsi', 'raw_affiliation_strings': ['Department of Immunology Faculty of Medicine University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091410175', 'display_name': 'László Virág', 'orcid': 'https://orcid.org/0000-0002-7099-6718'}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'László Virág', 'raw_affiliation_strings': ['Department of Medical Chemistry Faculty of Medicine University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Chemistry Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086657850', 'display_name': 'József Maléth', 'orcid': 'https://orcid.org/0000-0001-5768-3090'}, 'institutions': [{'id': 'https://openalex.org/I227486990', 'display_name': 'University of Szeged', 'ror': 'https://ror.org/01pnej532', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I227486990']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'József Maléth', 'raw_affiliation_strings': ['First Department of Medicine University of Szeged Szeged Hungary', 'HAS-USZ Momentum Epithelial Cell Signalling and Secretion Research Group University of Szeged Szeged Hungary'], 'affiliations': [{'raw_affiliation_string': 'First Department of Medicine University of Szeged Szeged Hungary', 'institution_ids': ['https://openalex.org/I227486990']}, {'raw_affiliation_string': 'HAS-USZ Momentum Epithelial Cell Signalling and Secretion Research Group University of Szeged Szeged Hungary', 'institution_ids': ['https://openalex.org/I227486990']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010425997', 'display_name': 'Gábor Koncz', 'orcid': 'https://orcid.org/0000-0002-4888-6838'}, 'institutions': [{'id': 'https://openalex.org/I132735039', 'display_name': 'University of Debrecen', 'ror': 'https://ror.org/02xf66n48', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I132735039']}], 'countries': ['HU'], 'is_corresponding': True, 'raw_author_name': 'Gábor Koncz', 'raw_affiliation_strings': ['Department of Immunology Faculty of Medicine University of Debrecen Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology Faculty of Medicine University of Debrecen Hungary', 'institution_ids': ['https://openalex.org/I132735039']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 7, 'corresponding_author_ids': ['https://openalex.org/A5025520088', 'https://openalex.org/A5042485976', 'https://openalex.org/A5016307875', 'https://openalex.org/A5082505630', 'https://openalex.org/A5087265496', 'https://openalex.org/A5040663379', 'https://openalex.org/A5039054439', 'https://openalex.org/A5074365621', 'https://openalex.org/A5063423811', 'https://openalex.org/A5061089265', 'https://openalex.org/A5103014310', 'https://openalex.org/A5049960571', 'https://openalex.org/A5019717640', 'https://openalex.org/A5090781260', 'https://openalex.org/A5091410175', 'https://openalex.org/A5086657850', 'https://openalex.org/A5010425997'], 'corresponding_institution_ids': ['https://openalex.org/I132735039', 'https://openalex.org/I227486990', 'https://openalex.org/I227486990', 'https://openalex.org/I132735039', 'https://openalex.org/I132735039', 'https://openalex.org/I132735039', 'https://openalex.org/I132735039', 'https://openalex.org/I132735039', 'https://openalex.org/I154526488', 'https://openalex.org/I201841394', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210106880', 'https://openalex.org/I4210106880', 'https://openalex.org/I4210106880', 'https://openalex.org/I2800351701', 'https://openalex.org/I132735039', 'https://openalex.org/I132735039', 'https://openalex.org/I227486990', 'https://openalex.org/I132735039'], 'apc_list': {'value': 4580, 'currency': 'USD', 'value_usd': 4580, 'provenance': 'doaj'}, 'apc_paid': {'value': 3500, 'currency': 'EUR', 'value_usd': 3774, 'provenance': 'openapc'}, 'fwci': 2.091, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.999982, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '288', 'issue': '22', 'first_page': '6476', 'last_page': '6491'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10294', 'display_name': 'Molecular Mechanisms of Apoptosis and Cell Death', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10294', 'display_name': 'Molecular Mechanisms of Apoptosis and Cell Death', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12672', 'display_name': 'Mechanisms of Apoptotic Cell Clearance and Immune Regulation', 'score': 0.9918, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10587', 'display_name': 'Role of Autophagy in Disease and Health', 'score': 0.9685, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/necroptosis', 'display_name': 'Necroptosis', 'score': 0.571941}, {'id': 'https://openalex.org/keywords/apoptosis', 'display_name': 'Apoptosis', 'score': 0.516018}], 'concepts': [{'id': 'https://openalex.org/C6929976', 'wikidata': 'https://www.wikidata.org/wiki/Q3771881', 'display_name': 'Regulator', 'level': 3, 'score': 0.83265924}, {'id': 'https://openalex.org/C94030615', 'wikidata': 'https://www.wikidata.org/wiki/Q3346925', 'display_name': 'Necroptosis', 'level': 4, 'score': 0.6140356}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.57200426}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5257198}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.49177292}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36885983}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3625713}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.32168764}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.23470202}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.13610202}], 'mesh': [], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/febs.15898', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.15898', 'source': {'id': 'https://openalex.org/S37672443', 'display_name': 'FEBS Journal', 'issn_l': '1742-464X', 'issn': ['1742-464X', '1742-4658'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/2437/309370', 'pdf_url': 'http://dea.lib.unideb.hu/bitstreams/90036610-d5d8-46ff-aab4-80b0887f8973/download', 'source': {'id': 'https://openalex.org/S4306402089', 'display_name': 'University of Debrecen Electronic Archive (University of Debrecen)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I132735039', 'host_organization_name': 'University of Debrecen', 'host_organization_lineage': ['https://openalex.org/I132735039'], 'host_organization_lineage_names': ['University of Debrecen'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://real.mtak.hu/137485/1/MolnarFEBSJ.pdf', 'pdf_url': 'http://real.mtak.hu/137485/1/MolnarFEBSJ.pdf', 'source': {'id': 'https://openalex.org/S4306400081', 'display_name': "Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)", 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I4210140733', 'host_organization_name': 'Library and Information Centre of the Hungarian Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/I4210140733'], 'host_organization_lineage_names': ['Library and Information Centre of the Hungarian Academy of Sciences'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://publicatio.bibl.u-szeged.hu/21977/1/MolnarTFEBSJ2021.pdf', 'pdf_url': 'https://publicatio.bibl.u-szeged.hu/21977/1/MolnarTFEBSJ2021.pdf', 'source': {'id': 'https://openalex.org/S4306400436', 'display_name': 'SZTE Publicatio Repozitórium (University of Szeged)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I227486990', 'host_organization_name': 'University of Szeged', 'host_organization_lineage': ['https://openalex.org/I227486990'], 'host_organization_lineage_names': ['University of Szeged'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33899329', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/febs.15898', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.15898', 'source': {'id': 'https://openalex.org/S37672443', 'display_name': 'FEBS Journal', 'issn_l': '1742-464X', 'issn': ['1742-464X', '1742-4658'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.85, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 60, 'referenced_works': ['https://openalex.org/W1515879175', 'https://openalex.org/W1523845694', 'https://openalex.org/W1862255621', 'https://openalex.org/W1895770990', 'https://openalex.org/W1964182229', 'https://openalex.org/W1964483580', 'https://openalex.org/W1966135296', 'https://openalex.org/W1971182364', 'https://openalex.org/W1974812554', 'https://openalex.org/W1978093163', 'https://openalex.org/W1979032223', 'https://openalex.org/W1986978728', 'https://openalex.org/W1988777405', 'https://openalex.org/W1994301968', 'https://openalex.org/W1997128330', 'https://openalex.org/W2004536546', 'https://openalex.org/W2010243701', 'https://openalex.org/W2010457616', 'https://openalex.org/W2010766264', 'https://openalex.org/W2014647723', 'https://openalex.org/W2033968700', 'https://openalex.org/W2034006241', 'https://openalex.org/W2038114873', 'https://openalex.org/W2039386747', 'https://openalex.org/W2045457634', 'https://openalex.org/W2049463960', 'https://openalex.org/W2050891951', 'https://openalex.org/W2052605153', 'https://openalex.org/W2055388969', 'https://openalex.org/W2060204808', 'https://openalex.org/W2071769633', 'https://openalex.org/W2085926680', 'https://openalex.org/W2091802222', 'https://openalex.org/W2098641105', 'https://openalex.org/W2104205504', 'https://openalex.org/W2108049791', 'https://openalex.org/W2110796758', 'https://openalex.org/W2116609506', 'https://openalex.org/W2119683782', 'https://openalex.org/W2120626244', 'https://openalex.org/W2124396497', 'https://openalex.org/W2127652350', 'https://openalex.org/W2133079836', 'https://openalex.org/W2160591179', 'https://openalex.org/W2160651627', 'https://openalex.org/W2164033133', 'https://openalex.org/W2170554156', 'https://openalex.org/W2170725518', 'https://openalex.org/W2342747586', 'https://openalex.org/W2418456889', 'https://openalex.org/W2518481037', 'https://openalex.org/W2556287713', 'https://openalex.org/W2583882253', 'https://openalex.org/W2740276651', 'https://openalex.org/W2788640168', 'https://openalex.org/W2896390248', 'https://openalex.org/W2901813822', 'https://openalex.org/W2967395171', 'https://openalex.org/W2987640418', 'https://openalex.org/W2994895262'], 'related_works': ['https://openalex.org/W4287092123', 'https://openalex.org/W3143577155', 'https://openalex.org/W2991355330', 'https://openalex.org/W2621136438', 'https://openalex.org/W243056473', 'https://openalex.org/W2087666519', 'https://openalex.org/W2071430672', 'https://openalex.org/W2020112528', 'https://openalex.org/W1952688415', 'https://openalex.org/W10561809'], 'abstract_inverted_index': {'Necroptosis': [0], 'is': [1, 18, 51], 'a': [2, 44, 190, 200], 'regulated': [3], 'necrotic-like': [4], 'cell': [5, 210], 'death': [6, 48, 78], 'modality': [7], 'which': [8], 'has': [9, 66], 'come': [10], 'into': [11], 'the': [12, 23, 56, 60, 74, 138, 145, 206], 'focus': [13], 'of': [14, 25, 59, 76, 115, 121, 134, 140, 147, 151, 169, 194, 209], 'attention': [15], 'since': [16], 'it': [17], 'known': [19, 159], 'to': [20, 22, 34, 118, 180, 204], 'contribute': [21], 'pathogenesis': [24], 'many': [26], 'inflammatory': [27], 'and': [28, 79, 96, 127, 129, 177, 196], 'degenerative': [29], 'diseases': [30], 'as': [31, 33, 43, 189], 'well': [32], 'tumor': [35], 'regulation.': [36], 'Based': [37], 'on': [38], 'current': [39], 'data,': [40], 'necroptosis': [41, 84, 167], 'serves': [42], 'backup': [45], 'mechanism': [46], 'when': [47], 'receptor-induced': [49], 'apoptosis': [50, 65], 'inhibited': [52], 'or': [53, 142, 157], 'absent.': [54], 'However,': [55], 'necroptotic': [57], 'role': [58], 'proteins': [61], 'involved': [62], 'in': [63, 88, 92, 105, 131], 'mitochondrial': [64], 'not': [67, 91], 'been': [68], 'investigated.': [69], 'Here,': [70], 'we': [71], 'demonstrated': [72], 'that': [73, 186], 'stimulation': [75], 'several': [77], 'pattern': [80], 'recognition': [81], 'receptors': [82], 'induced': [83], 'under': [85], 'caspase-compromised': [86], 'conditions': [87], 'wild-type,': [89], 'but': [90, 137], 'caspase-9-negative': [93], 'human': [94], 'Jurkat': [95], 'murine': [97], 'MEF': [98], 'cells.': [99], 'Cerulein-induced': [100], 'pancreatitis': [101], 'was': [102], 'significantly': [103], 'reduced': [104], 'mice': [106], 'with': [107], 'acinar': [108], 'cell-restricted': [109], 'caspase-9': [110, 116, 148, 176, 187, 198], 'gene': [111], 'knockout.': [112], 'The': [113], 'absence': [114], 'led': [117], 'impaired': [119], 'association': [120], 'receptor-interacting': [122], 'serine/threonine-protein': [123], 'kinase': [124, 154, 163], '1': [125], '(RIPK1)': [126], 'RIPK3': [128, 143], 'resulted': [130], 'decreased': [132], 'phosphorylation': [133], 'RIP': [135], 'kinases,': [136], 'overexpression': [139], 'RIPK1': [141], 'rescued': [144], 'effect': [146], 'deficiency.': [149], 'Inhibition': [150], 'either': [152], 'Aurora': [153], 'A': [155], '(AURKA)': [156], 'its': [158], 'substrate,': [160], 'glycogen': [161], 'synthase': [162], '3β': [164], '(GSK3ß)': [165], 'restored': [166], 'sensitivity': [168], 'caspase-9-deficient': [170], 'cells,': [171], 'indicating': [172], 'an': [173], 'interplay': [174], 'between': [175], 'AURKA-mediated': [178], 'pathways': [179], 'regulate': [181], 'necroptosis.': [182], 'Our': [183], 'findings': [184], 'suggest': [185], 'acts': [188], 'newly': [191], 'identified': [192], 'regulator': [193], 'necroptosis,': [195], 'thus,': [197], 'provides': [199], 'promising': [201], 'therapeutic': [202], 'target': [203], 'manipulate': [205], 'immunological': [207], 'outcome': [208], 'death.': [211]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3159813479', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 2}], 'updated_date': '2024-08-31T04:01:03.265817', 'created_date': '2021-05-10'}