Publication Information

{'id': 'https://openalex.org/W3158710047', 'doi': 'https://doi.org/10.1097/ju.0000000000001819', 'title': 'Distinct Response to Platinum-Based Chemotherapy among Patients with Metastatic Castration-Resistant Prostate Cancer Harboring Alterations in Genes Involved in Homologous Recombination', 'display_name': 'Distinct Response to Platinum-Based Chemotherapy among Patients with Metastatic Castration-Resistant Prostate Cancer Harboring Alterations in Genes Involved in Homologous Recombination', 'publication_year': 2021, 'publication_date': '2021-04-27', 'ids': {'openalex': 'https://openalex.org/W3158710047', 'doi': 'https://doi.org/10.1097/ju.0000000000001819', 'mag': '3158710047', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33904759'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/ju.0000000000001819', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 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1693], 'Shanghai': [62, 80, 98, 116, 134, 152, 170, 188, 206, 224, 243, 247, 270, 290, 294, 317, 1277, 1283, 1289, 1298, 1311, 1319, 1334, 1408, 1432, 1456, 1480, 1504, 1525, 1546, 1567, 1588, 1609, 1630, 1645, 1649, 1679, 1694, 1698, 1746, 1752, 1758, 1767, 1780, 1788, 1803], 'Jiao': [63, 81, 99, 117, 135, 153, 171, 189, 207, 225, 244, 271, 291, 318, 1299, 1312, 1335, 1409, 1433, 1457, 1481, 1505, 1526, 1547, 1568, 1589, 1610, 1631, 1646, 1680, 1695, 1768, 1781, 1804], 'Tong': [64, 82, 100, 118, 136, 154, 172, 190, 208, 226, 245, 272, 292, 319, 1300, 1313, 1336, 1410, 1434, 1458, 1482, 1506, 1527, 1548, 1569, 1590, 1611, 1632, 1647, 1681, 1696, 1769, 1782, 1805], 'University,': [65, 83, 101, 119, 137, 155, 173, 191, 209, 227, 246, 273, 293, 320, 1411, 1435, 1459, 1483, 1507, 1528, 1549, 1570, 1591, 1612, 1633, 1648, 1682, 1697], 'Shanghai,': [66, 84, 102, 120, 138, 156, 174, 192, 210, 228, 274, 321, 1412, 1436, 1460, 1484, 1508, 1529, 1550, 1571, 1592, 1613, 1634, 1683], 'China': [67, 85, 103, 121, 139, 157, 175, 193, 211, 229, 249, 275, 296, 322, 1263, 1413, 1437, 1461, 1485, 1509, 1530, 1551, 1572, 1593, 1614, 1635, 1651, 1684, 1700, 1732], ',': [68, 86, 104, 122, 140, 158, 176, 194, 212, 230, 276], 'FeiXiaochen': [70], 'Fei': [71, 1423], 'ZhuYinjie': [88], 'Zhu': [89, 1447], 'ChiChenfei': [106], 'Chi': [107, 1471], 'PanJiahua': [124], 'Pan': [125, 1495], 'ShaJianjun': [142], 'Sha': [143, 1516], 'XinZhixiang': [160], 'Xin': [161, 1537], 'GongYiming': [178], 'Gong': [179, 1558], 'DuXinxing': [196], 'Du': [197, 1579], 'WangYanqing': [214], 'Wang': [215, 1600], 'DongBaijun': [232], 'Dong': [233, 1621], '†Correspondence:': [234, 281, 1636, 1685], '200127,': [248, 295, 1650, 1699], 'telephone:': [250, 297, 1652, 1701], '+86': [251, 298, 1653, 1702], '21': [252, 299, 1654, 1703], '68383757;': [253, 300, 1655, 1704], 'E-mail': [254, 258, 301, 305, 1656, 1660, 1705, 1709], 'Address:': [255, 259, 302, 306, 1657, 1661, 1706, 1710], '[email': [256, 260, 303, 307, 1658, 1662, 1707, 1711], 'protected];': [257, 304, 1659, 1708], 'protected]': [261, 308, 1663, 1712], 'XueWei': [279], 'View': [323], 'All': [324, 1719], 'Author': [325], 'Informationhttps://doi.org/10.1097/JU.0000000000001819AboutFull': [326], 'TextPDF': [327], 'ToolsAdd': [328], 'favoritesDownload': [330], 'CitationsTrack': [331], 'CitationsPermissionsReprints': [332], 'ShareFacebookLinked': [333], 'InTwitterEmail': [334], 'Abstract': [335], 'Purpose:': [336], 'We': [337, 363], 'aimed': [338], 'explore': [340], 'the': [341, 378, 400, 421, 433, 573, 641, 829, 985, 1091, 1253, 1394, 1722], 'association': [342, 674], 'between': [343, 675, 803], 'genomic': [344, 385, 409, 565, 845, 875, 941, 1005, 1109, 1161], 'status': [345], 'clinical': [347, 602, 861, 954, 970, 1163, 1207], 'outcome': [348], 'platinum-based': [350, 375, 542, 559, 586, 682, 750], 'chemotherapy': [351, 376, 382, 683, 699, 729, 775], 'patients': [353, 370, 440, 482, 546, 632, 731, 782, 973, 1065, 1176, 1235], 'metastatic': [355, 660, 687, 701, 944, 1033, 1178], 'castration-resistant': [356, 661, 895, 945, 1010, 1179], 'prostate': [357, 416, 635, 662, 688, 702, 848, 879, 896, 914, 946, 976, 1011, 1034, 1137, 1157, 1180, 1205], 'cancer': [358, 636, 703, 849, 915, 927, 977, 1012, 1181], '(mCRPC).': [359], 'Materials': [360, 1360], 'Methods:': [362], 'conducted': [364], 'a': [365, 470, 1069, 1154, 1188], 'retrospective': [366], 'study': [367, 623, 1415, 1439, 1463, 1487], '55': [369, 405], 'mCRPC': [372, 548, 563], 'who': [373, 463, 1389], 'received': [374], 'after': [377, 638], 'progression': [379], 'docetaxel': [381], 'underwent': [384], 'profiling': [386, 846, 876], '14': [388], 'homologous': [389], 'recombination': [390, 720, 747, 826], '(HR)': [391], 'pathway': [392, 413, 1086], 'genes.': [393, 414, 1119], 'Progression-free': [394], 'survival': [395, 809], '(PFS)': [396], 'was': [397, 425], 'analyzed': [398], 'using': [399], 'Kaplan-Meier': [401], 'method.': [402], 'Results:': [403], 'Of': [404], 'patients,': [406], '23': [407], 'harbored': [408], 'defects': [410, 566, 1029], 'HR': [412, 422, 435, 443, 452, 518, 526, 553, 569], 'Median': [415], 'specific': [417], 'antigen': [418], '(PSA)-PFS': [419], 'for': [420, 432, 465, 972, 1307, 1326, 1776, 1795], 'defect': [423, 436, 444, 453, 487, 495, 504, 513, 519, 527, 532], 'group': [424, 437], '6.7': [426], 'months': [427, 431, 455], 'compared': [428, 508, 588], '2.6': [430], 'no': [434], '(p=0.001).': [438], 'The': [439, 460, 545, 673, 890, 940, 1104], 'harboring': [441, 450, 483, 493, 500, 511, 516, 549, 564, 591], 'somatic': [442, 856], 'displayed': [445, 479, 505, 555], 'shorter': [446], 'PSA-PFS': [447], 'than': [448, 490], 'those': [449, 492, 510, 515, 590], 'germline': [451, 574, 676, 854, 1048], '(4.5': [454], 'vs': [456], 'not': [457], 'available;': [458], 'p=0.066).': [459], 'PSA50': [461], '(patients': [462], 'survived': [464], '12': [466, 1134], 'weeks': [467], 'had': [469], 'PSA': [471], 'decline': [472], 'over': [473], '50%': [474], 'from': [475], 'baseline)': [476], 'response': [477, 557, 725, 1118], 'rate': [478], 'higher': [480], 'BRCA2': [484, 501, 529, 578, 657, 677, 771, 806], 'or': [485, 502, 530, 575, 629], 'ATM': [486, 503, 531], '(6/8,': [488], '75.0%)': [489], 'CDK12': [494, 512, 592, 1151], '(2/9,': [496], '22.2%;': [497], 'p=0.06).': [498], 'prolonged': [506], 'PSA-PFS,': [507], 'other': [517], '(p=0.038).': [520], 'In': [521], 'multivariate': [522], 'Cox': [523], 'regression': [524], 'analysis,': [525], 'were': [533], 'independent': [534], 'significant': [535], 'factors': [536], 'associated': [537], 'superior': [539, 583], 'PAS-PFS': [540], 'chemotherapy.': [543, 560], 'Conclusions:': [544], 'alterations': [550, 857, 1006, 1152], 'different': [552], 'genes': [554, 570], 'distinct': [556, 950, 1160], 'crucial': [568], 'either': [571, 627], 'somatic,': [576], 'especially': [577], 'ATM,': [580], 'might': [581], 'experience': [582], 'outcomes': [584, 752, 1130, 1211], 'chemotherapy,': [587], 'defect.': [593], 'References': [594], '1.': [595], ':': [596, 618, 653, 672, 697, 718, 745, 766, 801, 824, 843, 873, 889, 905, 925, 939, 964, 1001, 1027, 1046, 1061, 1084, 1103, 1128, 1147, 1173, 1203, 1232], 'cancer,': [598], 'version': [599], '2.2019,': [600], 'NCCN': [601], 'practice': [603], 'guidelines': [604], 'oncology.': [606], 'J': [607, 644, 992, 1018, 1038, 1075, 1244], 'Natl': [608], 'Compr': [609], 'Canc': [610], 'Netw': [611], '2019;': [612, 919, 958, 1078, 1246], '17:': [613], '479.': [614], 'Google': [615, 650, 669, 694, 715, 742, 763, 798, 821, 840, 870, 886, 902, 922, 936, 961, 998, 1024, 1043, 1058, 1081, 1100, 1125, 1144, 1170, 1200, 1229, 1249], 'Scholar': [616, 651, 670, 695, 716, 743, 764, 799, 822, 841, 871, 887, 903, 923, 937, 962, 999, 1025, 1044, 1059, 1082, 1101, 1126, 1145, 1171, 1201, 1230, 1250], '2.': [617], 'Multinational,': [619], 'double-blind,': [620], 'phase': [621, 1192], 'III': [622], 'prednisone': [625], 'satraplatin': [628], 'placebo': [630], 'castrate-refractory': [634], 'progressing': [637], 'prior': [639], 'chemotherapy:': [640], 'SPARC': [642], 'trial.': [643, 1194], 'Clin': [645, 736, 757, 993], 'Oncol': [646, 711, 866, 994, 1196, 1225], '2009;': [647], '27:': [648], '5431.': [649], '3.': [652], 'Biallelic': [654], 'inactivation': [655], 'platinum-sensitive': [659], 'cancer.': [663, 689, 735, 756, 785, 816, 834, 880, 897, 1035, 1138, 1241], 'Eur': [664, 917, 1139, 1165], 'Urol': [665, 918, 1019, 1140, 1166], '2016;': [666, 739, 1097], '69:': [667], '992.': [668], '4.': [671], 'variants': [678, 1049], 'sensitivity': [680], 'men': [685], '2017;': [691, 760, 867], '123:': [692], '3532.': [693], '5.': [696], 'Platinum-based': [698], 'DNA': [705, 907, 1016, 1116, 1183], 'repair': [706, 908, 1184], 'gene': [707, 778, 909, 1185], 'alterations.': [708], 'JCO': [709, 864, 1223], 'Precis': [710, 865, 1224], '2020;': [712, 1141, 1167, 1197, 1226], '4:': [713, 1227], '355.': [714, 1057], '6.': [717], 'deficiency': [721, 748], '(HRD)': [722], 'score': [723], 'predicts': [724], 'platinum-containing': [727], 'neoadjuvant': [728], 'triple-negative': [733], 'breast': [734, 755, 1067], 'Res': [738, 759], '22:': [740], '3764.': [741], '7.': [744], 'therapy': [751], 'advanced': [754, 1136, 1239], '23:': [761], '7521.': [762], '8.': [765], 'Association': [767, 802, 1350, 1369], 'BRCA1': [769, 804], 'mutations': [772, 807], 'survival,': [774], 'sensitivity,': [776], 'mutator': [779], 'phenotype': [780], 'ovarian': [784, 815, 833, 1240], 'Published': [786], 'correction': [787], 'appears': [788], 'JAMA': [790, 794, 817], '2012;': [791, 818, 899], '307:': [792, 819], '363.': [793], '2011;': [795, 1122], '306:': [796], '1557.': [797], '9.': [800], 'women': [811], 'invasive': [813], 'epithelial': [814], '382.': [820], '10.': [823, 869], 'deficiency:': [827], 'exploiting': [828], 'fundamental': [830], 'vulnerability': [831], 'Discov': [836], '2015;': [837, 1040], '5:': [838], '1137.': [839], '11.': [842, 885], 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