Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3148684177', 'doi': None, 'title': 'Molecular mechanisms regulating NLRP3 inflammasome activation', 'display_name': 'Molecular mechanisms regulating NLRP3 inflammasome activation', 'publication_year': 2016, 'publication_date': '2016-01-01', 'ids': {'openalex': 'https://openalex.org/W3148684177', 'mag': '3148684177'}, 'language': 'zh-cn', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://www.cqvip.com/QK/87787X/201602/668454248.html', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306541443', 'display_name': '中国免疫学杂志:英文版', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5088145455', 'display_name': 'Eun-Kyeong', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Eun-Kyeong', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5106465612', 'display_name': 'Jo', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jo', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105456331', 'display_name': 'Kexin Jin', 'orcid': 'https://orcid.org/0000-0001-8439-5916'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jin', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081750805', 'display_name': 'Kyung', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kyung', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103964144', 'display_name': 'Kim Kim', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kim', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091293971', 'display_name': 'Dong-min', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Dong-Min', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100619952', 'display_name': 'Kunyoo Shin', 'orcid': 'https://orcid.org/0000-0002-1519-9839'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Shin', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044654015', 'display_name': 'Chihiro', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Chihiro', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5019772543', 'display_name': 'Sasakawa', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Sasakawa', 'raw_affiliation_strings': [], 'affiliations': []}], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 74, 'max': 77}, 'biblio': {'volume': '13', 'issue': '2', 'first_page': '148', 'last_page': '159'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11078', 'display_name': 'Molecular Mechanisms of Inflammasome Activation and Regulation', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11078', 'display_name': 'Molecular Mechanisms of Inflammasome Activation and Regulation', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11337', 'display_name': 'Neuroimmune Interaction in Psychiatric Disorders', 'score': 0.9702, 'subfield': {'id': 'https://openalex.org/subfields/2803', 'display_name': 'Biological Psychiatry'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/aim2', 'display_name': 'AIM2', 'score': 0.71519464}, {'id': 'https://openalex.org/keywords/pyrin-domain', 'display_name': 'Pyrin domain', 'score': 0.6116744}, {'id': 'https://openalex.org/keywords/inflammasome', 'display_name': 'Inflammasome', 'score': 0.58945}, {'id': 'https://openalex.org/keywords/inflammation', 'display_name': 'Inflammation', 'score': 0.541193}, {'id': 'https://openalex.org/keywords/nlrp3', 'display_name': 'NLRP3', 'score': 0.537487}, {'id': 'https://openalex.org/keywords/interleukin-1', 'display_name': 'Interleukin-1', 'score': 0.519317}, {'id': 'https://openalex.org/keywords/pyroptosis', 'display_name': 'Pyroptosis', 'score': 0.5112029}, {'id': 'https://openalex.org/keywords/neuroinflammation', 'display_name': 'Neuroinflammation', 'score': 0.507709}], 'concepts': [{'id': 'https://openalex.org/C2777209026', 'wikidata': 'https://www.wikidata.org/wiki/Q412405', 'display_name': 'Inflammasome', 'level': 3, 'score': 0.9973346}, {'id': 'https://openalex.org/C139964883', 'wikidata': 'https://www.wikidata.org/wiki/Q14901964', 'display_name': 'Caspase 1', 'level': 4, 'score': 0.7210376}, {'id': 'https://openalex.org/C187831198', 'wikidata': 'https://www.wikidata.org/wiki/Q18034187', 'display_name': 'AIM2', 'level': 4, 'score': 0.71519464}, {'id': 'https://openalex.org/C139174496', 'wikidata': 'https://www.wikidata.org/wiki/Q24725912', 'display_name': 'Pyrin domain', 'level': 4, 'score': 0.6116744}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5328534}, {'id': 'https://openalex.org/C17172800', 'wikidata': 'https://www.wikidata.org/wiki/Q7263707', 'display_name': 'Pyroptosis', 'level': 4, 'score': 0.5112029}, {'id': 'https://openalex.org/C98539663', 'wikidata': 'https://www.wikidata.org/wiki/Q220599', 'display_name': 'Cytosol', 'level': 3, 'score': 0.46635452}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.43968132}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.28352678}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.28187895}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.23515645}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.12252763}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.051632464}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://www.cqvip.com/QK/87787X/201602/668454248.html', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306541443', 'display_name': '中国免疫学杂志:英文版', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3194414745', 'https://openalex.org/W3186053696', 'https://openalex.org/W3175784070', 'https://openalex.org/W3171235695', 'https://openalex.org/W3146331506', 'https://openalex.org/W3143156316', 'https://openalex.org/W3134150865', 'https://openalex.org/W3130082935', 'https://openalex.org/W3027136275', 'https://openalex.org/W3006994712', 'https://openalex.org/W2982503871', 'https://openalex.org/W2943293743', 'https://openalex.org/W2897382070', 'https://openalex.org/W2800938734', 'https://openalex.org/W2558550413', 'https://openalex.org/W2286744117', 'https://openalex.org/W2279561679', 'https://openalex.org/W2068633454', 'https://openalex.org/W174843022', 'https://openalex.org/W1542951095'], 'abstract_inverted_index': {'Inflammasomes': [0], '是表明触发煽动性的': [1], 'caspases': [2], '的激活和': [3], 'interleukin-1β': [4], '的成熟的建筑群的多蛋白质;。在各种各样的': [5], 'inflammasome': [6, 9, 14, 17, 21, 24, 27, 30], '建筑群之中,': [7], 'NLRP3': [8, 13, 16, 23, 26, 29], '最好被描绘并且与各种各样的人的': [10], 'autoinflammatory': [11], '和自体免疫的疾病被连接了。因此,': [12], '可以是为反煽动性的治疗的一个有希望的目标。在这评论,我们总结': [15], '被在': [18], 'cytosol': [19], '激活的机制的当前的理解。我们也描述激活或禁止': [20], '汇编的': [22], '建筑群的有约束力的搭挡。我们调整': [25], '发信号的机制的知识并且这些怎么影响煽动性的回答,提供进一步的卓见进潜在的治疗学的策略治疗与': [28], '的': [31], 'dysregulation': [32], '联系的煽动性的疾病。': [33]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3148684177', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-09-11T17:01:29.949315', 'created_date': '2021-04-13'}