Title: Association study between benign prostatic hyperplasia and primary hypertension
Abstract: Objective To assess whether primary hypertension affects the occurrence and progression of benign prostatic hyperplasia (BPH). Methods A total of 423 cases of BPH, undergoing transurethral resection of prostate (TURP) or open surgery due to severe low urinary tract symptoms, were reviewed and analyzed. All cases were verified to be BPH postoperatively following histopathological examination. Results Of 423 patients, 295 cases (69.7%) were simple BPH (group BPH-NT); 128 cases (30.3%) were BPH with hypertension (group BPH-HT). The mean age and the incidence of haematuria were significantly higher in group BPH-HT than those in group BPH-NT (P0.05). The time of BPH occurrence and surgical treatment in group BPH-HT with mean diastolic blood pressure ≥90 mmHg was significantly earlier than those with diastolic blood pressure 90 mmHg (P0.05; P0.01). As compared with group BPH-NT, the time of BPH occurrence was significantly earlier in group BPH-HT with more than 10 years hypertension; the rate of urinary retention and haematuria was significantly higher and prostatic volume was significantly greater in group BPH-HT with more than 20 years hypertension;(all P0.05). Additionally, prostatic volume was positively correlated with the years of hypertesion in group BPH-HT(Rsq=0.056,P=0.009). Conclusions The present results demonstrate that BPH may be frequently accompanied by the disease of hypertension. A long-term hypertension, particularly the condition of high diastolic blood pressure may improve the occurrence and clinical progression of BPH.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot