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'prognosis.': [314], 'Materials': [315, 1232], 'Methods:': [317], 'We': [318], 'retrospectively': [319], 'reviewed': [320], 'medical': [322], 'records': [323], 'patients': [325, 419, 814, 1021], 'who': [326], 'underwent': [327], 'radical': [328, 614, 751, 787, 926, 955, 1146, 1181], 'prostatectomy,': [329], 'we': [331, 386, 397], 'identified': [332], '580': [333], '(85.3%)': [334], 'concordant': [335, 400], 'cases': [336, 360, 401, 487], '100': [338], '(14.7%)': [339], 'cases.': [341], 'The': [342, 413, 452, 704, 864, 1018, 1165], 'end': [343], 'point': [344], 'this': [346, 1286, 1303, 1320, 1337, 1354, 1371, 1388, 1405, 1422, 1439, 1456, 1473], 'study': [347, 391, 414, 472, 480], 'was': [348, 354, 462, 465], 'biochemical': [349, 443, 454, 632, 784, 1178], 'recurrence,': [350], 'median': [352], 'followup': [353, 1050], '4.2': [355], 'years.': [356], 'Results:': [357], 'Among': [358], 'GGs': [363], 'GG': [371, 383, 407, 425, 435, 499], 'differed,': [373], 'majority': [375], '(67': [376], 'patients)': [377], 'had': [378], '2,': [384], 'set': [387], 'them': [388], 'as': [389, 409], 'cohort.': [392, 412], 'On': [393], 'other': [395], 'hand,': [396], 'regarded': [398], '212': [399], 'with': [402, 420, 430, 496, 791, 815, 1023, 1097], 'an': [403], '2': [408], 'control': [411, 460], 'cohort': [415, 461, 473, 1055], 'comprised': [416], '48': [417], '(71.6%)': [418], 'a': [421, 431, 727, 978, 1052, 1077, 1101, 1127], '3': [426], '19': [428], '(28.4%)': [429], '4/5.': [436], 'Kaplan-Meier': [437], 'curves': [438], 'revealed': [439], 'that': [440, 469, 482], '5-year': [442, 453], 'recurrence-free': [444, 455], 'survival': [445, 456], 'rates': [446], 'were': [447], '76%,': [448], '67%,': [450], 'respectively.': [451], 'rate': [457], '91%,': [463], 'significantly': [466], 'better': [467, 489], 'than': [468], '(p=0.013': [474], 'p=0.014,': [476], 'respectively).': [477], 'Conclusions:': [478], 'Our': [479], 'suggests': [481], 'prognosis': [484, 592], 'is': [488], 'determined': [490], 'by': [491, 634, 1196, 1219, 1238, 1285, 1302, 1319, 1336, 1353, 1370, 1387, 1404, 1421, 1438, 1455, 1472], 'instead': [500], 'lesion.': [504], 'References': [505], '1.': [506, 1112], ':': [507, 524, 543, 561, 581, 603, 629, 655, 679, 701, 741, 761, 778, 805, 828, 858, 889, 908, 946, 972, 995, 1017, 1037, 1066, 1092, 1116, 1138, 1164, 1191], 'cancer:': [510, 589, 1026, 1100], 'biologic,': [511], 'prognostic,': [512], 'therapeutic': [514], 'implications.': [515], 'Hum': [516], 'Pathol': [517, 734, 882, 939], '2010;': [518], '41:': [519], '781.': [520], 'Google': [521, 540, 558, 578, 600, 626, 652, 676, 698, 738, 758, 775, 802, 825, 855, 886, 905, 943, 969, 992, 1014, 1034, 1063, 1089, 1113, 1135, 1161, 1188, 1215], 'Scholar': [522, 541, 559, 579, 601, 627, 653, 677, 699, 739, 759, 776, 803, 826, 856, 887, 906, 944, 970, 993, 1015, 1035, 1064, 1090, 1114, 1136, 1162, 1189, 1216], '2.': [523], 'primary': [526], 'exhibits': [529], 'high': [530], 'degree': [531], 'genomic': [533], 'heterogeneity.': [534], 'Eur': [535, 595, 1130], 'Urol': [536, 596, 621, 671, 770, 797, 1031, 1059, 1085, 1131, 1156, 1183], '2019;': [537, 622, 902, 1185, 1212], '75:': [538], '498.': [539], '3.': [542], 'Heterogeneity': [544], 'Gleason': [546, 639, 715, 1042], 'grade': [547], 'multifocal': [549, 570, 747, 835, 1142], 'adenocarcinoma': [550, 661, 690], 'prostate.': [553, 693], '2004;': [555], '100:': [556], '2362.': [557], '4.': [560], 'Re-evaluating': [562], 'concept': [564], '"dominant/index': [566], 'nodule"': [568], 'cancer.': [572, 619, 647, 795, 817, 985, 1207], 'Virchows': [573], 'Arch': [574], '2014;': [575], '464:': [576], '589.': [577], '5.': [580], 'Current': [582], 'histopathologic': [583], 'molecular': [585], 'characterisations': [586], 'towards': [590], 'individualised': [591], 'therapies.': [594], '2016;': [597, 735], '69:': [598], '186.': [599], '6.': [602], 'Clinical': [604], 'usefulness': [605], 'volume': [610], 'related': [611], 'parameters': [612], 'following': [613], 'prostatectomy': [615, 752, 788, 927, 956, 997, 1147], 'for': [616, 644, 726, 959, 982, 1095, 1141, 1177], 'localized': [617, 645, 793], 'J': [620, 670, 732, 769, 796, 818, 880, 986, 1009, 1058, 1084, 1155], '201:': [623], '535.': [624], 'Link,': [625, 675, 774, 801, 1062, 1160], '7.': [628], 'Probability': [630], 'recurrence': [633, 785, 1179], 'analysis': [635, 1079], 'pathologic': [637], 'stage,': [638], 'score,': [640], 'margin': [642], 'status': [643], 'Urology': [648, 754], '2003;': [649, 1157], '62:': [650], '866.': [651], '8.': [654], 'Stage': [656], 'A': [657, 1048], 'versus': [658], 'B': [660], 'prostate:': [664, 1076, 1126], 'morphological': [665], 'comparison': [666], 'significance.': [669], '1988;': [672], '139:': [673], '61.': [674], '9.': [678], 'Histologic': [680], 'differentiation,': [681], 'pelvic': [685], 'lymph': [686], 'node': [687], 'metastasis': [688], '1990;': [695], '66:': [696], '1225.': [697], '10.': [700], 'Grading': [702], 'committee.': [703], '2014': [705], 'International': [706, 913], 'Society': [707], 'Urological': [709, 1221, 1240], 'Pathology': [710, 870, 917], '(ISUP)': [711, 871, 918], 'consensus': [712, 872, 919], 'conference': [713, 873, 920], 'on': [714, 874, 921], 'grading': [716, 722, 729, 860, 875], 'prostatic': [718, 877], 'carcinoma:': [719], 'definition': [720], 'patterns': [723], 'proposal': [725], 'new': [728], 'system.': [730], 'Am': [731, 879], 'Surg': [733, 881], '40:': [736], '244.': [737], '11.': [740], 'Morphologic': [742], 'clinical': [744], 'cancers': [749], 'specimens.': [753, 928], '2002;': [755], '60:': [756], '264.': [757], '12.': [760], 'Clinicopathological': [762], 'behavior': [763], 'single': [765], 'focus': [766], 'adenocarcinoma.': [768], '2009;': [771], '182:': [772], '2689.': [773], '13.': [777], 'Tumor': [779], 'focality': [780], 'does': [781, 1040], 'predict': [783, 1044], 'after': [786, 1180], 'men': [790], 'clinically': [792], '2011;': [798, 940, 966], '186:': [799], '506.': [800], '14.': [804], 'Evidence': [806], 'independent': [808, 840], 'origin': [809, 1170], 'multiple': [811, 839], 'tumors': [812], 'from': [813, 977], 'Natl': [819], 'Inst': [821], '1998;': [822], '90:': [823], '233.': [824], '15.': [827], 'Analysis': [829], 'genetic': [832], 'phylogeny': [833], 'identifies': [838], 'clonal': [841, 891], 'expansions': [842], 'neoplastic': [844], 'morphologically': [846], 'normal': [847], 'tissue.': [849], 'Nat': [850], 'Genet': [851], '2015;': [852, 989, 1110], '47:': [853], '367.': [854], '16.': [857, 942], 'ISUP': [859, 909], 'workshop': [861], 'panel': [862], 'members.': [863], '2019': [865], 'international': [866], 'society': [867, 914], 'urological': [869, 916], 'carcinoma.': [878], '2020;': [883, 1032], '44:': [884], 'e87.': [885], '17.': [888, 1134], 'Frequent': [890], 'relations': [892], 'between': [893, 1202], 'metastases': [894], 'non-index': [896], 'lesions.': [899], 'JCI': [900], 'Insight': [901], '4:': [903], 'e124756.': 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