Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3139492840', 'doi': 'https://doi.org/10.1016/j.celrep.2021.108857', 'title': 'Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy', 'display_name': 'Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy', 'publication_year': 2021, 'publication_date': '2021-03-01', 'ids': {'openalex': 'https://openalex.org/W3139492840', 'doi': 'https://doi.org/10.1016/j.celrep.2021.108857', 'mag': '3139492840', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33730565'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2021.108857', 'pdf_url': 'http://www.cell.com/article/S2211124721001716/pdf', 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.cell.com/article/S2211124721001716/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5021135178', 'display_name': 'Nicola D. Roverato', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Nicola D. Roverato', 'raw_affiliation_strings': ['Department of Biology, Division of Immunology, University of Konstanz, 78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Division of Immunology, University of Konstanz, 78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045296531', 'display_name': 'Carolin Sailer', 'orcid': 'https://orcid.org/0000-0001-7735-6070'}, 'institutions': [{'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Carolin Sailer', 'raw_affiliation_strings': ['Department of Biology, University of Konstanz, 78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, University of Konstanz, 78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049689768', 'display_name': 'Nicola Catone', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210132003', 'display_name': 'Biotechnology Institute Thurgau', 'ror': 'https://ror.org/030dhdf69', 'country_code': 'CH', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132003']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Nicola Catone', 'raw_affiliation_strings': ['Biotechnology Institute Thurgau at the University of Konstanz, 8280 Kreuzlingen, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Biotechnology Institute Thurgau at the University of Konstanz, 8280 Kreuzlingen, Switzerland', 'institution_ids': ['https://openalex.org/I4210132003']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074388281', 'display_name': 'Annette Aichem', 'orcid': 'https://orcid.org/0000-0001-7765-2160'}, 'institutions': [{'id': 'https://openalex.org/I4210132003', 'display_name': 'Biotechnology Institute Thurgau', 'ror': 'https://ror.org/030dhdf69', 'country_code': 'CH', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132003']}, {'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['CH', 'DE'], 'is_corresponding': False, 'raw_author_name': 'Annette Aichem', 'raw_affiliation_strings': ['Biotechnology Institute Thurgau at the University of Konstanz, 8280 Kreuzlingen, Switzerland', 'Department of Biology, Division of Immunology, University of Konstanz, 78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Biotechnology Institute Thurgau at the University of Konstanz, 8280 Kreuzlingen, Switzerland', 'institution_ids': ['https://openalex.org/I4210132003']}, {'raw_affiliation_string': 'Department of Biology, Division of Immunology, University of Konstanz, 78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006736501', 'display_name': 'Florian Stengel', 'orcid': 'https://orcid.org/0000-0003-1447-4509'}, 'institutions': [{'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Florian Stengel', 'raw_affiliation_strings': ['Department of Biology, University of Konstanz, 78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, University of Konstanz, 78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5023085770', 'display_name': 'Marcus Groettrup', 'orcid': 'https://orcid.org/0000-0002-5423-6399'}, 'institutions': [{'id': 'https://openalex.org/I4210132003', 'display_name': 'Biotechnology Institute Thurgau', 'ror': 'https://ror.org/030dhdf69', 'country_code': 'CH', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132003']}, {'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['CH', 'DE'], 'is_corresponding': True, 'raw_author_name': 'Marcus Groettrup', 'raw_affiliation_strings': ['Biotechnology Institute Thurgau at the University of Konstanz, 8280 Kreuzlingen, Switzerland', 'Department of Biology, Division of Immunology, University of Konstanz, 78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Biotechnology Institute Thurgau at the University of Konstanz, 8280 Kreuzlingen, Switzerland', 'institution_ids': ['https://openalex.org/I4210132003']}, {'raw_affiliation_string': 'Department of Biology, Division of Immunology, University of Konstanz, 78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5023085770'], 'corresponding_institution_ids': ['https://openalex.org/I4210132003', 'https://openalex.org/I189712700'], 'apc_list': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'apc_paid': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'fwci': 2.637, 'has_fulltext': False, 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.66748, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '34', 'issue': '11', 'first_page': '108857', 'last_page': '108857'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin-Proteasome Proteolytic Pathway', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin-Proteasome Proteolytic Pathway', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10587', 'display_name': 'Role of Autophagy in Disease and Health', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11772', 'display_name': 'Molecular Basis of Rett Syndrome and Related Disorders', 'score': 0.9921, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/e3-ubiquitin-ligases', 'display_name': 'E3 Ubiquitin Ligases', 'score': 0.552833}], 'concepts': [{'id': 'https://openalex.org/C2777668072', 'wikidata': 'https://www.wikidata.org/wiki/Q2472777', 'display_name': 'Parkin', 'level': 4, 'score': 0.99621916}, {'id': 'https://openalex.org/C134459356', 'wikidata': 'https://www.wikidata.org/wiki/Q4274835', 'display_name': 'Ubiquitin ligase', 'level': 4, 'score': 0.9263381}, {'id': 'https://openalex.org/C2779324830', 'wikidata': 'https://www.wikidata.org/wiki/Q1806192', 'display_name': 'Mitophagy', 'level': 4, 'score': 0.8312538}, {'id': 'https://openalex.org/C25602115', 'wikidata': 'https://www.wikidata.org/wiki/Q407111', 'display_name': 'Ubiquitin', 'level': 3, 'score': 0.7177103}, {'id': 'https://openalex.org/C27740335', 'wikidata': 'https://www.wikidata.org/wiki/Q14878333', 'display_name': 'Proteasome', 'level': 2, 'score': 0.49969578}, {'id': 'https://openalex.org/C2779734285', 'wikidata': 'https://www.wikidata.org/wiki/Q11085', 'display_name': "Parkinson's disease", 'level': 3, 'score': 0.49855614}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.43438515}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4265215}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.39039436}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3388185}, {'id': 'https://openalex.org/C203522944', 'wikidata': 'https://www.wikidata.org/wiki/Q288322', 'display_name': 'Autophagy', 'level': 3, 'score': 0.21713659}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.12699741}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.114581585}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.08927494}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08342841}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D063306', 'descriptor_name': 'Mitophagy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014452', 'descriptor_name': 'Ubiquitins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016923', 'descriptor_name': 'Cell Death', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020558', 'descriptor_name': 'GTP Phosphohydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020558', 'descriptor_name': 'GTP Phosphohydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057809', 'descriptor_name': 'HEK293 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D046988', 'descriptor_name': 'Proteasome Endopeptidase Complex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046988', 'descriptor_name': 'Proteasome Endopeptidase Complex', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D021381', 'descriptor_name': 'Protein Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059748', 'descriptor_name': 'Proteolysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054875', 'descriptor_name': 'Ubiquitination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014452', 'descriptor_name': 'Ubiquitins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2021.108857', 'pdf_url': 'http://www.cell.com/article/S2211124721001716/pdf', 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://nbn-resolving.de/urn:nbn:de:bsz:352-2-jpy86fkp1vqj3', 'pdf_url': 'https://kops.uni-konstanz.de/bitstreams/a2368c53-d203-4f04-8650-1079c3895924/download', 'source': {'id': 'https://openalex.org/S4377196311', 'display_name': 'KOPS (University of Konstanz)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I189712700', 'host_organization_name': 'University of Konstanz', 'host_organization_lineage': ['https://openalex.org/I189712700'], 'host_organization_lineage_names': ['University of Konstanz'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33730565', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2021.108857', 'pdf_url': 'http://www.cell.com/article/S2211124721001716/pdf', 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.84}], 'grants': [{'funder': 'https://openalex.org/F4320320875', 'funder_display_name': 'Deutscher Akademischer Austauschdienst', 'award_id': None}, {'funder': 'https://openalex.org/F4320320879', 'funder_display_name': 'Deutsche Forschungsgemeinschaft', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 74, 'referenced_works': ['https://openalex.org/W1839275362', 'https://openalex.org/W1957983000', 'https://openalex.org/W1963679398', 'https://openalex.org/W1966918485', 'https://openalex.org/W1972907808', 'https://openalex.org/W1976199333', 'https://openalex.org/W1978400610', 'https://openalex.org/W1980258775', 'https://openalex.org/W1991231925', 'https://openalex.org/W1995700909', 'https://openalex.org/W1996625702', 'https://openalex.org/W1996811776', 'https://openalex.org/W2000627845', 'https://openalex.org/W2016375853', 'https://openalex.org/W2022690300', 'https://openalex.org/W2025877652', 'https://openalex.org/W2027213843', 'https://openalex.org/W2032474599', 'https://openalex.org/W2032476721', 'https://openalex.org/W2032606025', 'https://openalex.org/W2038834667', 'https://openalex.org/W2041290559', 'https://openalex.org/W2042455211', 'https://openalex.org/W2043276141', 'https://openalex.org/W2046090070', 'https://openalex.org/W2047766237', 'https://openalex.org/W2053706533', 'https://openalex.org/W2054580886', 'https://openalex.org/W2061330513', 'https://openalex.org/W2064850779', 'https://openalex.org/W2069479107', 'https://openalex.org/W2070463829', 'https://openalex.org/W2072948635', 'https://openalex.org/W2080929675', 'https://openalex.org/W2081037153', 'https://openalex.org/W2087087126', 'https://openalex.org/W2093012444', 'https://openalex.org/W2095348121', 'https://openalex.org/W2106415502', 'https://openalex.org/W2113190139', 'https://openalex.org/W2113440807', 'https://openalex.org/W2114881821', 'https://openalex.org/W2121902398', 'https://openalex.org/W2138973636', 'https://openalex.org/W2140654974', 'https://openalex.org/W2141122215', 'https://openalex.org/W2142661697', 'https://openalex.org/W2144846851', 'https://openalex.org/W2151446023', 'https://openalex.org/W2155535303', 'https://openalex.org/W2156241187', 'https://openalex.org/W2580495962', 'https://openalex.org/W2581824660', 'https://openalex.org/W2590423871', 'https://openalex.org/W2735816534', 'https://openalex.org/W2762641371', 'https://openalex.org/W2783151804', 'https://openalex.org/W2790958817', 'https://openalex.org/W2794491744', 'https://openalex.org/W2800197308', 'https://openalex.org/W2805711807', 'https://openalex.org/W2810506792', 'https://openalex.org/W2810701500', 'https://openalex.org/W2811126749', 'https://openalex.org/W2851830164', 'https://openalex.org/W2886310907', 'https://openalex.org/W2889877280', 'https://openalex.org/W2897273152', 'https://openalex.org/W2913702886', 'https://openalex.org/W2914487443', 'https://openalex.org/W2977510709', 'https://openalex.org/W2980005681', 'https://openalex.org/W3035576629', 'https://openalex.org/W611331246'], 'related_works': ['https://openalex.org/W3010746757', 'https://openalex.org/W2886231497', 'https://openalex.org/W2805130622', 'https://openalex.org/W2616578517', 'https://openalex.org/W2598349524', 'https://openalex.org/W2593688553', 'https://openalex.org/W2517107066', 'https://openalex.org/W2415916782', 'https://openalex.org/W2052287001', 'https://openalex.org/W2013642338'], 'abstract_inverted_index': {'Parkin': [0, 29, 55, 64, 80, 90, 101, 126], 'is': [1], 'an': [2], 'E3': [3, 94], 'ubiquitin': [4], 'ligase': [5], 'belonging': [6], 'to': [7, 54, 66], 'the': [8, 13, 26, 31, 45, 67, 79], 'RING-between-RING': [9], 'family.': [10], 'Mutations': [11], 'in': [12, 60, 83, 86], 'Parkin-encoding': [14], 'gene': [15], 'PARK2': [16], 'are': [17], 'associated': [18], 'with': [19], 'familial': [20], "Parkinson's": [21, 141], 'disease.': [22, 142], 'Here,': [23], 'we': [24], 'investigate': [25], 'interplay': [27], 'between': [28], 'and': [30, 56, 75, 85, 105, 113, 127, 136], 'inflammatory': [32], 'cytokine-induced': [33], 'ubiquitin-like': [34], 'modifier': [35], 'FAT10.': [36], 'FAT10': [37, 51, 71, 93, 130], 'targets': [38], 'hundreds': [39], 'of': [40, 70, 78, 100, 110, 115, 118], 'proteins': [41], 'for': [42, 140], 'degradation': [43, 59], 'by': [44], '26S': [46], 'proteasome.': [47], 'We': [48], 'show': [49], 'that': [50], 'gets': [52], 'conjugated': [53], 'mediates': [57], 'its': [58, 103], 'a': [61, 92, 131], 'proteasome-dependent': [62], 'manner.': [63], 'binds': [65], 'E2': [68], 'enzyme': [69], '(USE1),': [72], 'auto-FAT10ylates': [73], 'itself,': [74], 'facilitates': [76], 'FAT10ylation': [77, 99, 124], 'substrate': [81], 'Mitofusin2': [82], 'vitro': [84], 'cells,': [87], 'thus': [88], 'identifying': [89], 'as': [91], 'ligase.': [95], 'On': [96], 'mitochondrial': [97], 'depolarization,': [98], 'inhibits': [102, 125], 'activation': [104], 'ubiquitin-ligase': [106], 'activity': [107], 'causing': [108], 'impairment': [109], 'mitophagy': [111, 128], 'progression': [112], 'aggravation': [114], 'rotenone-mediated': [116], 'death': [117], 'dopaminergic': [119], 'neuronal': [120], 'cells.': [121], 'In': [122], 'conclusion,': [123], 'rendering': [129], 'likely': [132], 'inflammation-induced': [133], 'exacerbating': [134], 'factor': [135], 'potential': [137], 'drug': [138], 'target': [139]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3139492840', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 10}, {'year': 2022, 'cited_by_count': 11}], 'updated_date': '2024-08-08T14:15:59.054938', 'created_date': '2021-03-29'}