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'we': [64, 425, 461, 511, 632, 653, 763, 836, 860, 979], 'COLGALT2': [66, 110, 138, 169, 189, 218, 281, 327, 338, 514, 528, 589, 624, 641, 731, 748, 768, 788, 803, 853, 963, 997], 'whose': [67], 'mRNA': [68], 'expression': [69, 111, 139, 154, 167, 180, 339, 515, 521, 544, 557, 568], 'was': [70, 155, 219, 232, 499, 545, 607, 642, 674, 854, 937], 'higher': [71, 109, 157, 179, 542, 805], 'copy': [73, 350, 590], 'number': [74, 351, 591], 'gained': [75, 990], '1B).': [78], 'then': [80, 324, 742], 'performed': [81, 462, 582, 981, 1104], 'immunohistochemistry': [82], '(IHC)': [83], 'tissue': [86, 134, 1025], 'microarray': [87], '(TMA)': [88], 'containing': [89], '80': [90], 'samples': [91], 'primary': [93, 141], 'cancer,': [95], '10': [96, 101], 'normal': [97], 'ovary': [98, 133], 'tissues,': [99], 'metastatic': [102, 159, 807], 'lesions': [103], '(Table': [104], 'S1).': [105], 'found': [107, 512, 594, 633, 654], 'significantly': [108, 156, 237, 256, 268, 370, 444, 634, 675, 712], 'both': [113, 188, 374, 778, 943], 'high-grade': [114], '(HG)': [115], 'low-grade': [117], '(LG)': [118], 'serous': [119], '(SOC),': [122], 'most': [124], 'common': [125], 'subtype': [126], 'OvCa,': [128, 971], 'compared': [129], 'healthy': [132], '2A).': [136], 'Whereas': [137], 'tumors': [142, 714, 728, 783], 'did': [143, 308, 837, 1021], 'not': [144, 309, 341, 406, 710, 838, 1022, 1155], 'differ': [145], 'by': [146, 502, 561, 852, 893, 1014, 1032, 1167], 'stage,': [147], 'metastasis,': [148], 'nodal': [149], 'status': [150], '1C),': [152], 'its': [153, 331], 'lesion': [160, 808], '2B).': [162], 'next': [164], 'measured': [165], 'constitutive': [166], 'four': [171], 'cell': [173, 213, 248, 258, 270, 381, 400, 536, 599, 615, 636], 'lines': [174, 214, 249, 537], 'ones': [177], '(SKOV3': [181], 'HEY-T30)': [183], 'one': [186], 'amplification': [190], 'overexpression': [192, 367], '(CAOV4)': [193], 'were': [194, 706, 1010, 1030, 1046], 'chosen': [195], 'for': [196, 1157, 1183], 'further': [197], 'study': [198, 721, 814, 822, 1020], '2C).': [200], 'first': [202], 'satisfactory': [204], 'knockdown': [205], '(KD)': [206], 'gene': [209, 355, 596, 601, 621], 'all': [211, 246, 316], 'three': [212, 247, 317], '2D).': [216], 'Endogenous': [217], 'difficult': [220], 'be': [222, 342, 1177], 'captured': [223], 'directly': [224], 'Western': [226], 'blotting': [227], 'FLAG': [230], 'tag': [231], 'used': [233, 300, 361, 426], '1D).': [235], 'COLGALT2-KD': [236, 254, 267, 307, 673], 'decreased': [238, 399, 635], 'proliferation': [239, 372], '2E)': [241], 'colony': [243, 446], 'formation': [244, 447], '(Figures': [250, 319, 645], '1E': [251], '2F).': [253], 'induced': [255], 'less': [257, 676], 'population': [259, 382, 388], 'G1': [261, 384], 'G2': [263], 'phases': [264], '1F).': [266], 'increased': [269, 343, 371, 380, 445], 'apoptosis': [271, 401, 415], 'significant': [273, 517, 532, 595, 656], 'increase': [274], 'caspase': [276], '3/7': [277], 'activity': [278, 285], '2G,H).': [280], 'harbors': [282], 'procollagen': [283, 878], 'participates': [287], 'chain': [290], 'trimerization': [291], 'degradation': [293], 'extracellular': [296, 887], 'matrix.2': [297], 'therefore': [299], 'pulse-chase': [301], 'assay': [302, 494], 'measure': [304], 'level.': [306], 'alter': [310], 'intra-': [311, 844], 'or': [312, 559, 563, 1026, 1160], 'extra-collagen': [313], 'level': [314, 732], 'cells': [318, 365, 376, 404, 409, 442, 467, 833], '1G': [320], '2I).': [322], '(OE)': [326], 'reversely': [329], 'validate': [330], 'role': [332], '2J).': [336, 357], 'Interestingly,': [337], 'could': [340, 416, 966], 'CAOV4': [345], 'cells,': [346], 'possibly': [347, 856], 'due': [348], 'thus': [359, 707, 918, 960], 'only': [360, 398, 497, 711], 'SKOV3': [362], 'HEY-T30': [364, 403], 'assays.': [368], 'COLGALT2-OE': [369, 379, 397, 452, 687], '2K).': [378], 'phase': [385, 391], 'reduced': [387], 'S': [390], '1H).': [393], 'Unlike': [394, 817], 'KD': [395, 736], 'scenario,': [396], 'but': [405, 715], 'SK-OV-3': [408, 466, 650], '2L).': [411], 'discrepancy': [413], 'result': [417, 606], 'from': [418, 879], 'single': [420], 'staining': [421], 'strategy': [422], '(Annexin': [423], 'V)': [424], 'flow': [428], 'cytometry': [429], '(Supporting': [430], 'Methods)': [431], 'failed': [433], 'distinguish': [435], 'early': [436], 'late': [438], 'apoptotic': [439], 'cells.': [440, 580], 'Both': [441], 'showed': [443, 481, 495, 516, 531, 769, 828, 926, 985], 'presence': [450], '1I,M).': [454], 'identify': [456], 'interacting': [457], 'partners': [458], 'COLGALT2,': [460], 'proteomic': [463], 'assays': [464, 983], 'COLGALT2-OE.': [469], 'mass': [471], 'spectrometry': [472], '(MS)': [473], 'yielded': [474], 'series': [476], 'candidate': [478], 'proteins': [479, 490], 'strong': [482, 770], 'network': [483], '3A).': [487], 'Amongst': [488], 'select': [489], 'interest,': [492], 'Co-IP': [493], 'PLOD3': [498, 520, 530, 543, 567, 571, 750, 776, 858, 894, 927, 965, 1000], 'pulled': [500], 'down': [501, 644], '×': [504], 'Flag-COLGALT2': [505], '3B).': [507], 'In': [508, 649, 977], 'TCGA': [509], 'cohort,': [510], 'correlation': [518, 533, 772], '3C).': [523], 'Similarly,': [524], 'protein': [525, 891], 'levels': [526], '3D).': [539], 'Of': [540], 'note,': [541], 'associated': [546], 'worsened': [548], 'prognosis': [549], 'patients': [552], 'either': [553], 'automatically': [555], 'designated': [556], 'cutoff': [558, 694], 'grouped': [560], 'top': [562, 618], 'lower': [564], '35%': [565], '3E).': [570], 'has': [572], 'been': [573, 947], 'reported': [574, 818], 'mediate': [576], 'invasiveness': [577, 1003], 'GSEA': [583], 'analysis': [584, 974], 'enrichment': [597], 'adhesion': [600, 616], 'set': [602], '3F).': [604], 'Similar': [605], 'also': [608, 716], 'obtained': [609], 'when': [610, 640], 'analyzed': [611], 'using': [612, 760], 'NET-GE': [613], 'showing': [614, 709], 'amongst': [617], 'five': [619], 'altered': [620], 'sets': [622], 'amplified': [625], '3G).': [628], 'Using': 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'models': [759], 'scoring': [761], 'system': [762], 'developed': [764, 1100], 'previously.3': [765], 'Expression': [766], 'positive': [771], 'vivo': [782], '3L,M;': [785], 'Table': [786], '1).': [787], 'an': [790], 'important': [791], 'paralog': [792], 'COLGALT1': [794, 936], 'promotes': [796, 919, 1002], 'maturation': [797], 'collagen.2': [799], 'Our': [800], 'finding': [801], 'supported': [810], 'latest': [813], 'osteosarcoma.4': [816], 'another': [820], 'landmark': [821], 'COLGALTs': [824], 'osteosarcoma': [826], 'accumulation': [830], 'lacking': [834], 'COLGALT1,5': [835], 'find': [839], 'alteration': [840], 'collagen,': [842], 'neither': [843], 'nor': [845], 'extracellular.': [846], 'speculate': [848], 'modification': [849], 'qualitative,': [855], 'as': [859], 'discovered.': [861], 'During': [862], 'synthesis,': [864], 'hydroxyproline': [865], 'undergoes': [866], 'lysyl': [867, 871, 901], 'hydroxylation': [868], 'PLOD-encoded': [870], 'hydroxylase': [872], '(LH)': [873], 'form': 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'authors.': [1169], 'Any': [1170], 'queries': [1171], '(other': [1172], 'missing': [1174], 'content)': [1175], 'should': [1176], 'directed': [1178], 'author': [1182], 'article.': [1185]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3139478941', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 3}], 'updated_date': '2024-12-27T00:29:23.380582', 'created_date': '2021-03-29'}