Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3133135927', 'doi': 'https://doi.org/10.1186/s12916-021-01915-8', 'title': 'Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study', 'display_name': 'Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study', 'publication_year': 2021, 'publication_date': '2021-02-15', 'ids': {'openalex': 'https://openalex.org/W3133135927', 'doi': 'https://doi.org/10.1186/s12916-021-01915-8', 'mag': '3133135927', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33583409', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7883435'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12916-021-01915-8', 'pdf_url': 'https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-021-01915-8', 'source': {'id': 'https://openalex.org/S135560524', 'display_name': 'BMC Medicine', 'issn_l': '1741-7015', 'issn': ['1741-7015'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-021-01915-8', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5066627009', 'display_name': 'Nicole Rübsamen', 'orcid': 'https://orcid.org/0000-0003-2198-5577'}, 'institutions': [{'id': 'https://openalex.org/I22465464', 'display_name': 'University of Münster', 'ror': 'https://ror.org/00pd74e08', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I22465464']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'Nicole Rübsamen', 'raw_affiliation_strings': ['Institute of Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany', 'institution_ids': ['https://openalex.org/I22465464']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084095818', 'display_name': 'Aleksandra Maceski', 'orcid': 'https://orcid.org/0000-0002-1916-5927'}, 'institutions': [{'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}, {'id': 'https://openalex.org/I2802542264', 'display_name': 'University Hospital of Basel', 'ror': 'https://ror.org/04k51q396', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802542264']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Aleksandra Maceski', 'raw_affiliation_strings': ['Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland', 'institution_ids': ['https://openalex.org/I1850255', 'https://openalex.org/I2802542264']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076575343', 'display_name': 'David Leppert', 'orcid': 'https://orcid.org/0000-0001-6172-801X'}, 'institutions': [{'id': 'https://openalex.org/I2802542264', 'display_name': 'University Hospital of Basel', 'ror': 'https://ror.org/04k51q396', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802542264']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'David Leppert', 'raw_affiliation_strings': ['Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland', 'institution_ids': ['https://openalex.org/I2802542264', 'https://openalex.org/I1850255']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080501336', 'display_name': 'Pascal Benkert', 'orcid': 'https://orcid.org/0000-0001-6525-8174'}, 'institutions': [{'id': 'https://openalex.org/I2802542264', 'display_name': 'University Hospital of Basel', 'ror': 'https://ror.org/04k51q396', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802542264']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Pascal Benkert', 'raw_affiliation_strings': ['Clinical Trial Unit, Department of Clinical Research, University Hospital Basel, University of Basel, Spitalstr 12, 4031, Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Clinical Trial Unit, Department of Clinical Research, University Hospital Basel, University of Basel, Spitalstr 12, 4031, Basel, Switzerland', 'institution_ids': ['https://openalex.org/I2802542264', 'https://openalex.org/I1850255']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045590592', 'display_name': 'Jens Kühle', 'orcid': 'https://orcid.org/0000-0002-6963-8892'}, 'institutions': [{'id': 'https://openalex.org/I2802542264', 'display_name': 'University Hospital of Basel', 'ror': 'https://ror.org/04k51q396', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802542264']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Jens Kuhle', 'raw_affiliation_strings': ['Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland', 'institution_ids': ['https://openalex.org/I2802542264', 'https://openalex.org/I1850255']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038373894', 'display_name': 'Heinz Wiendl', 'orcid': 'https://orcid.org/0000-0003-4310-3432'}, 'institutions': [{'id': 'https://openalex.org/I4210103666', 'display_name': 'University Hospital Münster', 'ror': 'https://ror.org/01856cw59', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103666']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Heinz Wiendl', 'raw_affiliation_strings': ['Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Albert-Schweitzer-Straße 33, 48149, Münster, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Albert-Schweitzer-Straße 33, 48149, Münster, Germany', 'institution_ids': ['https://openalex.org/I4210103666']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088727034', 'display_name': 'Annette Peters', 'orcid': 'https://orcid.org/0000-0001-6645-0985'}, 'institutions': [{'id': 'https://openalex.org/I3018134672', 'display_name': 'Helmholtz Zentrum München', 'ror': 'https://ror.org/00cfam450', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I3018134672']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Annette Peters', 'raw_affiliation_strings': ['Institute of Epidemiology II, Helmholtz Zentrum München, Ingolstädter Landstr 1, 85764, Neuherberg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Epidemiology II, Helmholtz Zentrum München, Ingolstädter Landstr 1, 85764, Neuherberg, Germany', 'institution_ids': ['https://openalex.org/I3018134672']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083896047', 'display_name': 'André Karch', 'orcid': 'https://orcid.org/0000-0003-3014-8543'}, 'institutions': [{'id': 'https://openalex.org/I22465464', 'display_name': 'University of Münster', 'ror': 'https://ror.org/00pd74e08', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I22465464']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'André Karch', 'raw_affiliation_strings': ['Institute of Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany', 'institution_ids': ['https://openalex.org/I22465464']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5067198140', 'display_name': 'Klaus Berger', 'orcid': 'https://orcid.org/0000-0001-8966-3684'}, 'institutions': [{'id': 'https://openalex.org/I22465464', 'display_name': 'University of Münster', 'ror': 'https://ror.org/00pd74e08', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I22465464']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Klaus Berger', 'raw_affiliation_strings': ['Institute of Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany', 'institution_ids': ['https://openalex.org/I22465464']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5066627009'], 'corresponding_institution_ids': ['https://openalex.org/I22465464'], 'apc_list': {'value': 2490, 'currency': 'GBP', 'value_usd': 3054, 'provenance': 'doaj'}, 'apc_paid': {'value': 2490, 'currency': 'GBP', 'value_usd': 3054, 'provenance': 'doaj'}, 'fwci': 4.165, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 36, 'citation_normalized_percentile': {'value': 0.999904, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '19', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10235', 'display_name': 'Health disparities and outcomes', 'score': 0.9568, 'subfield': {'id': 'https://openalex.org/subfields/3306', 'display_name': 'Health'}, 'field': {'id': 'https://openalex.org/fields/33', 'display_name': 'Social Sciences'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10235', 'display_name': 'Health disparities and outcomes', 'score': 0.9568, 'subfield': {'id': 'https://openalex.org/subfields/3306', 'display_name': 'Health'}, 'field': {'id': 'https://openalex.org/fields/33', 'display_name': 'Social Sciences'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, {'id': 'https://openalex.org/T10676', 'display_name': 'Genetics, Aging, and Longevity in Model Organisms', 'score': 0.9322, 'subfield': {'id': 'https://openalex.org/subfields/1302', 'display_name': 'Aging'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10924', 'display_name': 'Cardiovascular Health and Disease Prevention', 'score': 0.9264, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.955838}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.47441146}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.40396658}, {'id': 'https://openalex.org/C74909509', 'wikidata': 'https://www.wikidata.org/wiki/Q10387', 'display_name': 'Gerontology', 'level': 1, 'score': 0.4029018}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.33211237}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.32251766}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.1383444}], 'mesh': [{'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D007382', 'descriptor_name': 'Intermediate Filaments', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D019636', 'descriptor_name': 'Neurodegenerative Diseases', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D016900', 'descriptor_name': 'Neurofilament Proteins', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D016875', 'descriptor_name': 'tau Proteins', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003430', 'descriptor_name': 'Cross-Sectional Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005858', 'descriptor_name': 'Germany', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007382', 'descriptor_name': 'Intermediate Filaments', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008279', 'descriptor_name': 'Magnetic Resonance Imaging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019636', 'descriptor_name': 'Neurodegenerative Diseases', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D019636', 'descriptor_name': 'Neurodegenerative Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016900', 'descriptor_name': 'Neurofilament Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009483', 'descriptor_name': 'Neuropsychological Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016875', 'descriptor_name': 'tau Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12916-021-01915-8', 'pdf_url': 'https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-021-01915-8', 'source': {'id': 'https://openalex.org/S135560524', 'display_name': 'BMC Medicine', 'issn_l': '1741-7015', 'issn': ['1741-7015'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/12a1c0cce78249478345aeffa9c9f3bb', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883435', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33583409', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12916-021-01915-8', 'pdf_url': 'https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-021-01915-8', 'source': {'id': 'https://openalex.org/S135560524', 'display_name': 'BMC Medicine', 'issn_l': '1741-7015', 'issn': ['1741-7015'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.87, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320320879', 'funder_display_name': 'Deutsche Forschungsgemeinschaft', 'award_id': 'BE1996/1-1'}], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W1514778037', 'https://openalex.org/W1637545857', 'https://openalex.org/W1971211622', 'https://openalex.org/W1975726028', 'https://openalex.org/W1985468742', 'https://openalex.org/W1987690347', 'https://openalex.org/W1999684482', 'https://openalex.org/W2010050882', 'https://openalex.org/W2015568638', 'https://openalex.org/W2015704709', 'https://openalex.org/W2056196309', 'https://openalex.org/W2064867241', 'https://openalex.org/W2100809123', 'https://openalex.org/W2105087430', 'https://openalex.org/W2113676816', 'https://openalex.org/W2115098571', 'https://openalex.org/W2119910794', 'https://openalex.org/W2120357670', 'https://openalex.org/W2127227566', 'https://openalex.org/W2130383679', 'https://openalex.org/W2154286581', 'https://openalex.org/W2224720476', 'https://openalex.org/W2316564488', 'https://openalex.org/W2342233016', 'https://openalex.org/W2587612122', 'https://openalex.org/W2605036205', 'https://openalex.org/W2806791998', 'https://openalex.org/W2811179428', 'https://openalex.org/W2825486869', 'https://openalex.org/W2872969486', 'https://openalex.org/W2889223700', 'https://openalex.org/W2922315794', 'https://openalex.org/W2943273256', 'https://openalex.org/W2944409027', 'https://openalex.org/W2949225738', 'https://openalex.org/W2972371909', 'https://openalex.org/W2974879600', 'https://openalex.org/W2990895678', 'https://openalex.org/W3004767455', 'https://openalex.org/W3006577702', 'https://openalex.org/W3012618838', 'https://openalex.org/W3042808641', 'https://openalex.org/W3084246142'], 'related_works': ['https://openalex.org/W2391409986', 'https://openalex.org/W2159000141', 'https://openalex.org/W2132898409', 'https://openalex.org/W2037631372', 'https://openalex.org/W2030889776', 'https://openalex.org/W1979139803', 'https://openalex.org/W1978297557', 'https://openalex.org/W1974041167', 'https://openalex.org/W1966775726', 'https://openalex.org/W1966504330'], 'abstract_inverted_index': {'Abstract': [0], 'Background': [1], 'Neurofilament': [2], 'light': [3], 'chain': [4], '(NfL)': [5], 'is': [6, 15, 21, 285, 333], 'a': [7, 22, 120, 224, 241, 301, 322], 'cytoskeletal': [8], 'protein': [9, 24], 'component': [10], 'whose': [11], 'release': [12], 'into': [13], 'blood': [14, 142], 'indicative': [16], 'of': [17, 96, 132, 156, 300, 303], 'neuronal': [18], 'damage.': [19], 'Tau': [20], 'microtubule-associated': [23], 'in': [25, 42, 48, 70, 107, 112, 119, 279, 290], 'neurons': [26], 'and': [27, 35, 58, 88, 103, 110, 127, 136, 179, 201, 246, 263, 273, 276, 306, 310], 'strongly': [28], 'associated': [29, 39, 209, 258], 'with': [30, 40, 210, 259, 292], 'overall': [31, 68], 'brain': [32, 89, 185, 247, 264, 274], 'degeneration.': [33], 'NfL': [34, 57, 135, 195, 253, 270], 'tau': [36, 59, 137, 202], 'levels': [37, 61, 206, 255, 272, 318], 'are': [38, 52], 'mortality': [41, 69, 327], 'different': [43, 171], 'neurological': [44, 75, 283], 'diseases,': [45], 'but': [46, 214, 236, 314], 'studies': [47], 'the': [49, 80, 108, 133, 153, 157, 163, 177, 180, 218, 298], 'general': [50], 'population': [51], 'missing.': [53], 'We': [54], 'investigated': [55, 79, 188], 'whether': [56], 'serum': [60, 205, 254, 271, 317], 'could': [62], 'serve': [63, 320], 'as': [64, 321], 'prognostic': [65, 154, 219, 323], 'markers': [66], 'for': [67, 170, 325], 'elderly': [71], 'individuals': [72, 280], 'without': [73, 281], 'pre-defined': [74], 'conditions.': [76], 'Further,': [77], 'we': [78], 'cross-sectional': [81], 'associations': [82], 'between': [83, 176, 269], 'NfL,': [84, 213, 313], 'tau,': [85, 216, 316], 'neuropsychological': [86, 125, 181, 250, 260, 277], 'functioning,': [87], 'structures.': [90, 265], 'Methods': [91], 'In': [92], '1997,': [93], '385': [94], 'inhabitants': [95], 'Augsburg': [97, 113], 'who': [98], 'were': [99, 105, 138, 168, 187, 207, 256], 'aged': [100], '65': [101], 'years': [102], 'older': [104], 'included': [106], 'Memory': [109], 'Morbidity': [111], 'Elderly': [114], '(MEMO)': [115], 'study.': [116], 'They': [117], 'participated': [118], 'face-to-face': [121], 'medical': [122], 'interview': [123], 'including': [124], 'tests': [126], 'magnetic': [128], 'resonance': [129], 'imaging': [130], '(MRI)': [131], 'brain.': [134], 'measured': [139], 'from': [140], 'non-fasting': [141], 'samples': [143], 'using': [144, 189], 'highly': [145], 'sensitive': [146], 'single': [147], 'molecule': [148], 'array': [149], 'assays.': [150], 'To': [151], 'assess': [152], 'accuracy': [155, 220], 'biomarkers,': [158], 'concordance': [159], 'statistics': [160], 'based': [161], 'on': [162], 'predicted': [164], '5-year': [165], 'survival': [166], 'probabilities': [167], 'calculated': [169], 'Cox': [172], 'regression': [173], 'models.': [174], 'Associations': [175], 'biomarkers': [178], 'test': [182, 251, 261], 'scores': [183, 262], 'or': [184, 191, 249], 'structures': [186], 'linear': [190], 'logistic': [192], 'regression.': [193], 'Results': [194], '(HR': [196], '1.27,': [197], '95%': [198], 'CI': [199], '[1.14–1.42])': [200], '(1.20': [203], '[1.07–1.35])': [204], 'independently': [208], 'all-cause': [211, 326], 'mortality.': [212], 'not': [215, 237, 315], 'increased': [217], 'when': [221, 238], 'added': [222, 239], 'to': [223, 240, 287], 'model': [225, 242], 'containing': [226, 243], 'sociodemographic': [227, 244], 'characteristics': [228, 245], '(concordance': [229], 'statistic': [230], '0.684': [231], '[0.612–0.755]': [232], 'vs.': [233], '0.663': [234], '[0.593–0.733]),': [235], 'atrophy': [248, 275], 'scores.': [252], 'cross-sectionally': [257], 'Conclusions': [266], 'The': [267], 'association': [268], 'performance': [278], 'overt': [282], 'disease': [284], 'similar': [286], 'that': [288], 'seen': [289], 'patients': [291], 'neurodegenerative': [293], 'diseases.': [294], 'These': [295], 'findings': [296], 'support': [297], 'concept': [299], 'continuum': [302], 'physiological': [304], 'aging': [305], 'incipient,': [307], 'subclinical': [308], 'pathology,': [309], 'manifest': [311], 'disease.': [312], 'might': [319], 'marker': [324], 'if': [328], 'no': [329], 'other': [330], 'clinical': [331], 'information': [332], 'available.': [334]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3133135927', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 14}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 3}], 'updated_date': '2025-01-09T18:35:25.915110', 'created_date': '2021-03-01'}