Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3129654138', 'doi': 'https://doi.org/10.1016/j.anai.2021.02.011', 'title': 'The use of intravenous tranexamic acid for patients with angiotensin-converting enzyme inhibitor–induced angioedema', 'display_name': 'The use of intravenous tranexamic acid for patients with angiotensin-converting enzyme inhibitor–induced angioedema', 'publication_year': 2021, 'publication_date': '2021-02-16', 'ids': {'openalex': 'https://openalex.org/W3129654138', 'doi': 'https://doi.org/10.1016/j.anai.2021.02.011', 'mag': '3129654138', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33592284'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.anai.2021.02.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S153558830', 'display_name': 'Annals of Allergy Asthma & Immunology', 'issn_l': '1081-1206', 'issn': ['1081-1206', '1534-4436'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5057454808', 'display_name': 'Jose Manuel Martinez Manzano', 'orcid': 'https://orcid.org/0000-0002-5688-9692'}, 'institutions': [{'id': 'https://openalex.org/I2801887358', 'display_name': 'Einstein Medical Center Philadelphia', 'ror': 'https://ror.org/03vzpaf33', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801887358', 'https://openalex.org/I4210111876']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jose Manuel Martinez Manzano', 'raw_affiliation_strings': ['Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania', 'institution_ids': ['https://openalex.org/I2801887358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008788846', 'display_name': 'Kevin Bryan Lo', 'orcid': 'https://orcid.org/0000-0001-7088-6677'}, 'institutions': [{'id': 'https://openalex.org/I2801887358', 'display_name': 'Einstein Medical Center Philadelphia', 'ror': 'https://ror.org/03vzpaf33', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801887358', 'https://openalex.org/I4210111876']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kevin Bryan Lo', 'raw_affiliation_strings': ['Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania', 'institution_ids': ['https://openalex.org/I2801887358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010001737', 'display_name': 'Gabriel Patarroyo‐Aponte', 'orcid': 'https://orcid.org/0000-0002-2676-6747'}, 'institutions': [{'id': 'https://openalex.org/I2801887358', 'display_name': 'Einstein Medical Center Philadelphia', 'ror': 'https://ror.org/03vzpaf33', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801887358', 'https://openalex.org/I4210111876']}, {'id': 'https://openalex.org/I149251103', 'display_name': 'Thomas Jefferson University', 'ror': 'https://ror.org/00ysqcn41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I149251103']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gabriel Patarroyo-Aponte', 'raw_affiliation_strings': ['Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania', 'Department of Medicine, Sidney Kimmel Medical College Thomas Jefferson University, Philadelphia, Pennsylvania', 'Division of Pulmonary, Critical Care, and Sleep Medicine, Einstein Medical Center, Philadelphia, Pennsylvania'], 'affiliations': [{'raw_affiliation_string': 'Division of Pulmonary, Critical Care, and Sleep Medicine, Einstein Medical Center, Philadelphia, Pennsylvania', 'institution_ids': ['https://openalex.org/I2801887358']}, {'raw_affiliation_string': 'Department of Medicine, Sidney Kimmel Medical College Thomas Jefferson University, Philadelphia, Pennsylvania', 'institution_ids': ['https://openalex.org/I149251103']}, {'raw_affiliation_string': 'Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania', 'institution_ids': ['https://openalex.org/I2801887358']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5085593211', 'display_name': 'Zurab Azmaiparashvili', 'orcid': 'https://orcid.org/0000-0002-4070-2184'}, 'institutions': [{'id': 'https://openalex.org/I149251103', 'display_name': 'Thomas Jefferson University', 'ror': 'https://ror.org/00ysqcn41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I149251103']}, {'id': 'https://openalex.org/I2801887358', 'display_name': 'Einstein Medical Center Philadelphia', 'ror': 'https://ror.org/03vzpaf33', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801887358', 'https://openalex.org/I4210111876']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Zurab Azmaiparashvili', 'raw_affiliation_strings': ['Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania', 'Department of Medicine, Sidney Kimmel Medical College Thomas Jefferson University, Philadelphia, Pennsylvania'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Sidney Kimmel Medical College Thomas Jefferson University, Philadelphia, Pennsylvania', 'institution_ids': ['https://openalex.org/I149251103']}, {'raw_affiliation_string': 'Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania', 'institution_ids': ['https://openalex.org/I2801887358']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.592, 'has_fulltext': False, 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.822221, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 77, 'max': 80}, 'biblio': {'volume': '126', 'issue': '6', 'first_page': '725', 'last_page': '726'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11917', 'display_name': 'Hereditary Angioedema: Molecular Mechanisms and Clinical Management', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11917', 'display_name': 'Hereditary Angioedema: Molecular Mechanisms and Clinical Management', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11001', 'display_name': 'Renin-Angiotensin System in Cardiovascular Physiology and Pathology', 'score': 0.9437, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11346', 'display_name': 'Role of Mast Cells in Immunoregulation and Disease', 'score': 0.9429, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/intravenous-use', 'display_name': 'Intravenous use', 'score': 0.67318285}, {'id': 'https://openalex.org/keywords/intravenous-regional-anesthesia', 'display_name': 'Intravenous regional anesthesia', 'score': 0.48587602}, {'id': 'https://openalex.org/keywords/hereditary-angioedema', 'display_name': 'Hereditary Angioedema', 'score': 0.48038}, {'id': 'https://openalex.org/keywords/intravenous-infusions', 'display_name': 'Intravenous Infusions', 'score': 0.46958843}], 'concepts': [{'id': 'https://openalex.org/C2779637338', 'wikidata': 'https://www.wikidata.org/wiki/Q418666', 'display_name': 'Tranexamic acid', 'level': 3, 'score': 0.92312145}, {'id': 'https://openalex.org/C2777995640', 'wikidata': 'https://www.wikidata.org/wiki/Q1129007', 'display_name': 'Angioedema', 'level': 2, 'score': 0.8423299}, {'id': 'https://openalex.org/C2910922878', 'wikidata': 'https://www.wikidata.org/wiki/Q640448', 'display_name': 'Intravenous use', 'level': 2, 'score': 0.67318285}, {'id': 'https://openalex.org/C27016395', 'wikidata': 'https://www.wikidata.org/wiki/Q128861', 'display_name': 'Angiotensin-converting enzyme', 'level': 3, 'score': 0.6008084}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.51622796}, {'id': 'https://openalex.org/C2778835552', 'wikidata': 'https://www.wikidata.org/wiki/Q1671581', 'display_name': 'Intravenous regional anesthesia', 'level': 3, 'score': 0.48587602}, {'id': 'https://openalex.org/C2911027401', 'wikidata': 'https://www.wikidata.org/wiki/Q640448', 'display_name': 'Intravenous Infusions', 'level': 2, 'score': 0.46958843}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.42985332}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.33782345}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19960448}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.14951184}, {'id': 'https://openalex.org/C2991743468', 'wikidata': 'https://www.wikidata.org/wiki/Q166019', 'display_name': 'Blood loss', 'level': 2, 'score': 0.09521061}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.059552312}, {'id': 'https://openalex.org/C2779400597', 'wikidata': 'https://www.wikidata.org/wiki/Q1132870', 'display_name': 'Tourniquet', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000799', 'descriptor_name': 'Angioedema', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000799', 'descriptor_name': 'Angioedema', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D000806', 'descriptor_name': 'Angiotensin-Converting Enzyme Inhibitors', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D000933', 'descriptor_name': 'Antifibrinolytic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D017706', 'descriptor_name': 'Lisinopril', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D014148', 'descriptor_name': 'Tranexamic Acid', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D061605', 'descriptor_name': 'Administration, Intravenous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000799', 'descriptor_name': 'Angioedema', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000806', 'descriptor_name': 'Angiotensin-Converting Enzyme Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000933', 'descriptor_name': 'Antifibrinolytic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017706', 'descriptor_name': 'Lisinopril', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014148', 'descriptor_name': 'Tranexamic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.anai.2021.02.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S153558830', 'display_name': 'Annals of Allergy Asthma & Immunology', 'issn_l': '1081-1206', 'issn': ['1081-1206', '1534-4436'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33592284', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.61}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W1938048423', 'https://openalex.org/W1988251619', 'https://openalex.org/W1999733114', 'https://openalex.org/W2030391290', 'https://openalex.org/W2038331078', 'https://openalex.org/W2099412855', 'https://openalex.org/W2320955869', 'https://openalex.org/W2754142831', 'https://openalex.org/W2782889067', 'https://openalex.org/W2802687489', 'https://openalex.org/W4320300902'], 'related_works': ['https://openalex.org/W4386434497', 'https://openalex.org/W4367152686', 'https://openalex.org/W4299002920', 'https://openalex.org/W2791438051', 'https://openalex.org/W2590244377', 'https://openalex.org/W2217187009', 'https://openalex.org/W2094166105', 'https://openalex.org/W2090811440', 'https://openalex.org/W2001557425', 'https://openalex.org/W1982809308'], 'abstract_inverted_index': {'Angiotensin-converting': [0, 10], 'enzyme': [1], 'inhibitor': [2], '(ACEI)–induced': [3], 'angioedema': [4], 'was': [5], 'first': [6], 'described': [7], 'in': [8], '1984.1': [9], 'enzymes': [11], '(ACE)': [12], 'break': [13], 'down': [14], 'bradykinin': [15, 24], 'to': [16], 'inactive': [17], 'products.': [18], 'In': [19], 'turn,': [20], 'the': [21], 'inhibition': [22], 'of': [23], 'breakdown': [25], 'may': [26], 'provoke': [27], 'angioedema.2': [28]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3129654138', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-09-18T04:40:56.820840', 'created_date': '2021-03-01'}