Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3128128613', 'doi': 'https://doi.org/10.1002/ctm2.318', 'title': 'Identifying circulating glioma cells and their clusters as diagnostic markers by a novel detection platform', 'display_name': 'Identifying circulating glioma cells and their clusters as diagnostic markers by a novel detection platform', 'publication_year': 2021, 'publication_date': '2021-02-01', 'ids': {'openalex': 'https://openalex.org/W3128128613', 'doi': 'https://doi.org/10.1002/ctm2.318', 'mag': '3128128613', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33634975', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7862585'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/ctm2.318', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ctm2.318', 'source': {'id': 'https://openalex.org/S2765071679', 'display_name': 'Clinical and Translational Medicine', 'issn_l': '2001-1326', 'issn': ['2001-1326'], 'is_oa': True, 'is_in_doaj': True, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ctm2.318', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050167556', 'display_name': 'Yangzhi Qi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yangzhi Qi', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048469154', 'display_name': 'Qian Sun', 'orcid': 'https://orcid.org/0000-0002-8038-0706'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qian Sun', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101474966', 'display_name': 'Gang Deng', 'orcid': 'https://orcid.org/0000-0002-3363-3512'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Gang Deng', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022102562', 'display_name': 'Huikai Zhang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Huikai Zhang', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049187488', 'display_name': 'Yang Xu', 'orcid': 'https://orcid.org/0000-0002-0340-1163'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yang Xu', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036864133', 'display_name': 'Yuane Li', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151591', 'display_name': 'Wuhan YZY Biopharma (China)', 'ror': 'https://ror.org/03wcqja14', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I4210151591']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuane Li', 'raw_affiliation_strings': ['Department of Circulating Tumor Cells, YZY Medical Technological Company, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Circulating Tumor Cells, YZY Medical Technological Company, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210151591']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110411721', 'display_name': 'Shao-Yi Huang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151591', 'display_name': 'Wuhan YZY Biopharma (China)', 'ror': 'https://ror.org/03wcqja14', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I4210151591']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shaoyi Huang', 'raw_affiliation_strings': ['Department of Circulating Tumor Cells, YZY Medical Technological Company, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Circulating Tumor Cells, YZY Medical Technological Company, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210151591']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029768249', 'display_name': 'Yong Li', 'orcid': 'https://orcid.org/0000-0002-8910-9787'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yong Li', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5115590655', 'display_name': 'Zhang Ye', 'orcid': 'https://orcid.org/0000-0003-3495-5596'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhang Ye', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100408478', 'display_name': 'Yixuan Wang', 'orcid': 'https://orcid.org/0000-0003-3079-5572'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yixuan Wang', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080272047', 'display_name': 'Fanen Yuan', 'orcid': 'https://orcid.org/0000-0001-9484-5183'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Fanen Yuan', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071232347', 'display_name': 'Ping Hu', 'orcid': 'https://orcid.org/0009-0008-4626-0162'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ping Hu', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039663089', 'display_name': 'Lun Gao', 'orcid': 'https://orcid.org/0000-0002-0933-212X'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lun Gao', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040294237', 'display_name': 'Hongxiang Jiang', 'orcid': 'https://orcid.org/0000-0002-6752-0946'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongxiang Jiang', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112737672', 'display_name': 'Wenya Wu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151591', 'display_name': 'Wuhan YZY Biopharma (China)', 'ror': 'https://ror.org/03wcqja14', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I4210151591']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenya Wu', 'raw_affiliation_strings': ['Department of Circulating Tumor Cells, YZY Medical Technological Company, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Circulating Tumor Cells, YZY Medical Technological Company, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210151591']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101775832', 'display_name': 'Baohui Liu', 'orcid': 'https://orcid.org/0000-0001-5821-6945'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Baohui Liu', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5108064843', 'display_name': 'Qianxue Chen', 'orcid': 'https://orcid.org/0000-0002-9413-1030'}, 'institutions': [{'id': 'https://openalex.org/I4210140357', 'display_name': 'Renmin Hospital of Wuhan University', 'ror': 'https://ror.org/03ekhbz91', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210140357']}, {'id': 'https://openalex.org/I37461747', 'display_name': 'Wuhan University', 'ror': 'https://ror.org/033vjfk17', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I37461747']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Qianxue Chen', 'raw_affiliation_strings': ['Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Key laboratory of Renmin hospital, Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747']}, {'raw_affiliation_string': 'Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P.R. China', 'institution_ids': ['https://openalex.org/I37461747', 'https://openalex.org/I4210140357']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5101775832', 'https://openalex.org/A5108064843'], 'corresponding_institution_ids': ['https://openalex.org/I4210140357', 'https://openalex.org/I37461747', 'https://openalex.org/I4210140357', 'https://openalex.org/I37461747'], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.89723, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '11', 'issue': '2', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10336', 'display_name': 'Cancer Cells and Metastasis', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10336', 'display_name': 'Cancer Cells and Metastasis', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11255', 'display_name': 'Microfluidic and Bio-sensing Technologies', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11289', 'display_name': 'Single-cell and spatial transcriptomics', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/circulating-tumor-cell', 'display_name': 'Circulating tumor cell', 'score': 0.8512347}, {'id': 'https://openalex.org/keywords/isolation', 'display_name': 'Isolation', 'score': 0.4863046}, {'id': 'https://openalex.org/keywords/limiting', 'display_name': 'Limiting', 'score': 0.47817832}], 'concepts': [{'id': 'https://openalex.org/C61238886', 'wikidata': 'https://www.wikidata.org/wiki/Q5121689', 'display_name': 'Circulating tumor cell', 'level': 4, 'score': 0.8512347}, {'id': 'https://openalex.org/C2778227246', 'wikidata': 'https://www.wikidata.org/wiki/Q1365309', 'display_name': 'Glioma', 'level': 2, 'score': 0.82258093}, {'id': 'https://openalex.org/C2775941552', 'wikidata': 'https://www.wikidata.org/wiki/Q25212305', 'display_name': 'Isolation (microbiology)', 'level': 2, 'score': 0.4863046}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4856383}, {'id': 'https://openalex.org/C188198153', 'wikidata': 'https://www.wikidata.org/wiki/Q1613840', 'display_name': 'Limiting', 'level': 2, 'score': 0.47817832}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.41604507}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.41398954}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.33809036}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.24836984}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.20063046}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.18260738}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.18176305}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.15124741}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.15099916}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005910', 'descriptor_name': 'Glioma', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D009360', 'descriptor_name': 'Neoplastic Cells, Circulating', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005910', 'descriptor_name': 'Glioma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/ctm2.318', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ctm2.318', 'source': {'id': 'https://openalex.org/S2765071679', 'display_name': 'Clinical and Translational Medicine', 'issn_l': '2001-1326', 'issn': ['2001-1326'], 'is_oa': True, 'is_in_doaj': True, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/55dec0d06b784ae0ab0252a92ba105d6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862585', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33634975', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/ctm2.318', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ctm2.318', 'source': {'id': 'https://openalex.org/S2765071679', 'display_name': 'Clinical and Translational Medicine', 'issn_l': '2001-1326', 'issn': ['2001-1326'], 'is_oa': True, 'is_in_doaj': True, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.83, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81572489'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81502175'}], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W2111963329', 'https://openalex.org/W2128177155', 'https://openalex.org/W2140417249', 'https://openalex.org/W2148977460', 'https://openalex.org/W2508865759', 'https://openalex.org/W2560273089', 'https://openalex.org/W2883806203', 'https://openalex.org/W2912696928', 'https://openalex.org/W2970109182', 'https://openalex.org/W2982601398', 'https://openalex.org/W4234865248'], 'related_works': ['https://openalex.org/W4205796194', 'https://openalex.org/W3214677928', 'https://openalex.org/W3208778134', 'https://openalex.org/W3005931108', 'https://openalex.org/W2923544662', 'https://openalex.org/W2604647756', 'https://openalex.org/W2234322404', 'https://openalex.org/W2169223304', 'https://openalex.org/W2085056052', 'https://openalex.org/W1986811797'], 'abstract_inverted_index': {'Dear': [0], 'editor:': [1], 'Diffused': [2], 'glioma': [3, 70, 154, 248, 265, 401, 410, 503, 528, 647, 691, 883, 967, 992], 'is': [4, 113, 920, 1205], 'the': [5, 87, 145, 191, 320, 336, 395, 406, 471, 496, 502, 522, 596, 616, 636, 711, 781, 834, 921, 927, 956, 987, 1016, 1037, 1071, 1079, 1100, 1108, 1120, 1142, 1155, 1162, 1167, 1177, 1180, 1183, 1191, 1209, 1219, 1231, 1235], 'leading': [6], 'cause': [7], 'of': [8, 90, 106, 126, 148, 179, 322, 335, 347, 349, 397, 473, 498, 524, 612, 620, 639, 643, 687, 720, 814, 836, 864, 890, 923, 929, 959, 990, 1021, 1040, 1065, 1078, 1082, 1099, 1103, 1110, 1171, 1182, 1199, 1213], 'central': [9], 'nervous': [10], 'system': [11], 'tumor-related': [12], 'deaths': [13], 'worldwide.1': [14], 'As': [15], 'a': [16, 64, 100, 117, 123, 130, 345, 540, 577, 590, 640, 675, 718, 900, 938, 1000], 'non-invasive': [17], 'and': [18, 27, 36, 40, 72, 83, 85, 158, 162, 185, 200, 212, 258, 292, 316, 325, 354, 369, 380, 484, 518, 632, 670, 785, 800, 816, 839, 866, 885, 893, 913, 949, 978, 994, 997, 1027, 1045, 1075, 1128, 1139, 1152, 1159, 1169, 1174, 1186, 1189], 'convenient': [19], 'bio-marker,': [20], 'despite': [21], 'that': [22, 236, 253, 272, 357, 508, 535, 558, 580, 652, 683, 735, 765, 792, 824, 861], 'circulating': [23, 69, 991], 'tumor': [24, 34, 81, 108, 139, 277, 584], 'cells': [25, 71, 109, 173, 187, 217, 332, 429, 456], '(CTC)': [26], 'their': [28, 38, 73, 78, 886, 980, 995], 'clusters': [29, 74, 624, 645, 694, 737, 817, 841, 867, 887], 'show': [30], 'great': [31], 'feasibility': [32, 396, 472], 'in': [33, 56, 80, 232, 366, 400, 413, 476, 491, 501, 509, 526, 563, 567, 589, 646, 747, 937, 946, 966, 1166], 'diagnosis': [35, 82, 597], 'management,2': [37], 'isolation': [39, 102, 112], 'identification': [41, 245, 260, 273, 297], 'remain': [42, 968], 'challenging,': [43], 'limiting': [44], 'further': [45, 76, 469, 779, 944], 'clinical': [46, 93, 403, 787, 933, 981, 988, 1008, 1156], 'application.3-7': [47], 'Therefore,': [48, 339], 'more': [49, 383, 598, 626], 'efficient': [50, 879], 'detection': [51], 'platforms': [52], 'are': [53, 868, 973, 1113], 'urgently': [54, 974], 'required': [55, 975], 'this': [57, 96, 149, 414, 492, 1066, 1111, 1115, 1131], 'field.': [58], 'This': [59, 574, 634, 918], 'inspired': [60], 'us': [61], 'to': [62, 67, 330, 549, 603, 666, 714, 797, 845, 911, 915, 1007, 1230], 'fabricate': [63], 'novel': [65, 101], 'platform': [66, 399, 475, 880], 'detect': [68], 'for': [75, 92, 135, 247, 352, 545, 759, 872, 881, 905, 932, 976, 1002, 1208, 1234], 'evaluated': [77], 'value': [79, 287, 523], 'management,': [84], 'highlight': [86], 'wider': [88], 'potential': [89, 579, 928, 1197], 'CTC': [91, 227, 266, 281, 315, 500, 525, 529, 537, 559, 582, 606, 653, 766, 784, 793, 815, 828, 838, 865, 884, 898, 941, 1003], 'application.': [94, 934], 'In': [95, 169, 708, 874], 'study,': [97, 415, 551, 925], 'we': [98, 340, 556, 809, 876], 'performed': [99, 1141, 1154], 'method': [103], 'by': [104, 303, 659, 1015, 1057, 1070, 1218], 'size': [105], 'epithelial': [107], 'device.': [110], 'The': [111, 203, 1010, 1032, 1051, 1062, 1193, 1203], 'carried': [114], 'out': [115], 'using': [116, 581], 'biocompatible': [118], 'parylene': [119], 'polymer': [120], 'membrane': [121], 'with': [122, 344, 443, 481, 486, 615, 661, 678, 689, 717, 772, 888, 1179], 'pore': [124], 'diameter': [125], '8': [127], 'μm': [128], 'under': [129, 1094], 'high': [131, 326, 891], 'flow': [132], 'rate,': [133], 'enriching': [134], 'CTCs': [136, 451], 'without': [137], 'requiring': [138], 'cell-specific': [140], 'capture': [141, 146, 192, 204], 'antibodies.': [142], 'To': [143, 468], 'test': [144], 'efficiency': [147, 193, 205], 'device,': [150], 'two': [151], 'common': [152], 'malignant': [153, 350], 'cell': [155, 656, 993], 'lines,': [156], 'U87': [157, 172], 'U251,': [159], 'were': [160, 194, 206, 489, 769, 842, 1068, 1087, 1164], 'selected': [161], 'spiked': [163, 171], 'into': [164], 'healthy': [165, 331, 370, 1092], "donors'": [166], 'blood': [167, 175, 219, 755], 'samples.': [168], 'detecting': [170, 215, 882], 'from': [174, 218, 267, 668, 1004, 1089, 1119], 'samples': [176, 220], 'at': [177, 221, 818], 'concentrations': [178, 223], '5,': [180], '10,': [181], '20,': [182], '50,': [183], '100,': [184], '150': [186], 'per': [188, 430, 457, 698, 723], '5': [189, 431, 458, 724], 'ml,': [190, 432, 459], '86.0%,': [195, 198], '87.0%,': [196], '86.5%,': [197], '91.3%,': [199], '92.9%,': [201], 'respectively.': [202], '80.0%,': [207], '77.0%,': [208], '81.5%,': [209], '78.6%,': [210], '84.3%,': [211], '86.2%': [213], 'when': [214], 'U251': [216], 'above': [222, 452], '(Figure': [224, 288, 372, 388, 437, 464, 516, 530, 569, 628, 704, 730, 751, 775, 806, 831, 856], '1A-C).': [225], 'Besides,': [226], 'cluster': [228, 607, 697, 722], 'was': [229, 238, 381, 504, 561, 608, 635, 745, 757, 795, 1013, 1054], 'not': [230, 239, 263, 869, 1206], 'observed': [231, 746, 810], 'any': [233, 1214], 'test,': [234], 'confirming': [235], 'it': [237, 593], 'artifact.': [240], 'We': [241, 392, 494, 600, 681, 777, 895], 'then': [242, 778], 'investigate': [243, 470, 780], 'feasible': [244, 259], 'methods': [246, 274, 298], 'CTC.': [249], 'Our': [250, 789, 983], 'data': [251, 790, 1086, 1157], 'showed': [252], "Wright's": [254, 386], 'staining,': [255, 305, 763], 'one': [256, 754], 'convincing': [257], 'method,8': [261], 'could': [262, 538, 594, 738, 942], 'distinguish': [264], 'other': [268], 'brain': [269, 487, 511], "tumors',": [270], 'indicating': [271, 734, 823], 'based': [275, 309], 'on': [276, 310], 'features': [278, 351], 'cannot': [279], 'define': [280], 'origin,': [282], 'which': [283, 907], 'limit': [284], 'its': [285], 'diagnostic': [286, 543, 903], '4A-C;': [289], 'Tables': [290], 'S1': [291], 'S2).': [293], 'However,': [294, 742], 'highly': [295, 541, 901], 'specific': [296, 542, 902], 'targeted': [299], 'GBM-derived': [300], 'CTC,': [301, 421], 'represented': [302], 'STEAM': [304, 342, 359], 'an': [306, 609, 811, 878], 'antibody': [307], 'cocktail': [308], 'differential': [311, 477], 'expressed': [312], 'genes': [313], 'between': [314, 783], 'WBC,': [317], 'would': [318], 'increase': [319, 813], 'risk': [321], 'false': [323], 'positives': [324], 'background': [327, 364], 'levels': [328, 365, 560, 835, 863], 'due': [329], 'expressing': [333], 'several': [334], 'included': [337], 'markers.3': [338], 'combined': [341], 'staining': [343, 360, 387], 'series': [346], 'criteria': [348], 'CTC,8': [353], 'subsequently': [355], 'proved': [356], 'modified': [358], 'can': [361, 654], 'remarkably': [362, 422], 'decrease': [363], 'mouse': [367], 'experiments': [368, 1064], 'donors': [371, 1093], '1D-F;': [373], 'Figure': [374, 376, 571, 630], '2A,B;': [375], '4D;': [377], 'Table': [378, 390, 439, 466, 706, 732], 'S3),': [379, 733], 'also': [382, 998, 1034], 'sensitive': [384], 'than': [385, 424, 507, 853, 1224], '2C;': [389], 'S4).': [391], 'next': [393, 601], 'examine': [394], 'our': [398, 474, 924], 'through': [402, 673], 'test.': [404], 'Of': [405], '42': [407], 'primary': [408, 690], 'diffused': [409, 546], 'patients': [411, 442, 448, 480, 688, 1090], 'enrolled': [412, 490], 'nearly': [416, 684], '85.7%': [417], '(36/42)': [418], 'had': [419, 449, 692], 'detectable': [420, 450], 'higher': [423, 506, 562, 862], 'previous': [425, 550, 773, 953], 'study': [426, 650, 774, 954, 1012, 1112], '(median:': [427, 454, 695], '5.0': [428], 'range:': [433, 460, 700], '0–13,': [434], 'mean:': [435, 462, 702, 728], '5.5±3.0)': [436], '2D;': [438, 465], 'S5).': [440], 'For': [441], 'recurred': [444], 'glioma,': [445, 710, 906], '7/8': [446], '(87.5%)': [447], 'threshold': [453], '5.5': [455], '0–18,': [461], '7.3±6.3)': [463], 'S3).': [467, 707], 'diagnosis,': [478], '20': [479], 'benign': [482], 'tumors': [483, 512], 'eight': [485], 'metastasis': [488], 'study.': [493, 1132], 'found': [495, 557, 682], 'level': [497, 794], 'STEAM-positive': [499, 536, 897], 'significantly': [505], 'above-mentioned': [510], '(P': [513, 803, 848], '<': [514, 804, 849], '.0001)': [515], '2E)': [517], 'ROC': [519], 'curves': [520], 'revealed': [521, 791], 'predicting': [527, 583], '2F).': [531], 'These': [532], 'findings': [533, 859, 984, 1109], 'demonstrated': [534], 'be': [539, 909, 943, 1228], 'bio-marker': [544], 'glioma.': [547, 613, 873], 'Contrary': [548], 'among': [552], 'five': [553], 'pathological': [554, 585, 947], 'subtypes,': [555], 'astrocytoma': [564], 'while': [565], 'lower': [566], 'oligodendroglioma': [568], '2G-I;': [570], '4E).4,': [572], '7': [573], 'finding': [575, 919], 'shed': [576], 'new': [578], 'subtypes.': [586], 'After': [587, 935], 'verified': [588], 'larger': [591, 939], 'cohort,': [592, 940], 'make': [595], 'accurate.': [599], 'sought': [602], 'determine': [604], 'whether': [605], 'intrinsic': [610], 'property': [611], 'Compared': [614], 'extremely': [617, 985], 'low': [618], 'proportion': [619, 712], 'CTC-CTC': [621], 'clusters,9': [622], 'CTC-WBC': [623, 644, 693, 736, 840, 960], 'occurred': [625], 'frequently': [627], '3A;': [629], '4F': [631], '4G).': [633], 'first': [637], 'report': [638], 'large': [641], 'number': [642], 'patients.': [648], 'Previous': [649], 'reported': [651], 'enable': [655], 'cycle': [657], 'progression': [658], 'binding': [660], 'neutrophils,': [662, 770], 'highlighting': [663, 926], "CTC's": [664], 'ability': [665], 'escape': [667], 'anoikis': [669], 'immune': [671], 'surveillance': [672], 'making': [674], 'stable': [676], 'niche': [677], 'non-tumor': [679], 'cells.10': [680], '33.3%': [685], '(14/42)': [686], '0': [696], 'mL,': [699], '0–3,': [701], '0.6±0.9)': [703], '3B,': [705, 731], 'recurrent': [709], 'increased': [713], '75%': [715], '(6/8),': [716], 'median': [719], '1': [721], 'ml': [725], '(range:': [726], '0–2,': [727], '0.9±0.6)': [729], 'help': [739, 1181], 'monitoring': [740], 'recurrence.': [741], 'no': [743, 1196], 'difference': [744], 'different': [748], 'pathologic': [749], 'subtypes': [750, 948], '3C).': [752], 'Subsequently,': [753], 'sample': [756], 'presented': [758], 'Wright': [760], '&': [761], 'Giemsa': [762], 'showing': [764], 'associated': [767], 'WBCs': [768], 'consistent': [771], '3D).10': [776], 'correlation': [782], "patients'": [786], 'features.': [788], 'related': [796, 844, 971], 'IDH': [798, 854], 'status': [799, 855], 'poor': [801], 'outcomes': [802], '.05)': [805], '3E).': [807], 'Interestingly,': [808], 'impressive': [812], '2': [819], 'weeks': [820], 'after': [821], 'resection,': [822], 'resection': [825], 'might': [826, 908], 'promote': [827], 'entering': [829], 'circulation': [830], '3F).': [832], 'Moreover,': [833], 'postoperative': [837], 'positively': [843], 'P53': [846], 'mutation': [847], '.05,': [850], 'respectively)': [851], 'rather': [852], '3G).': [857], 'Above': [858], 'suggested': [860], 'favorable': [870], 'predictors': [871], 'conclusion,': [875], 'present': [877, 1011], 'advantages': [889], 'sensitivity': [892], 'specificity.': [894], 'identified': [896], 'as': [899], 'marker': [904], 'superior': [910], 'MRI': [912], 'biopsy': [914, 931], 'some': [916], 'extent.': [917], 'strength': [922], 'liquid': [930], 'validation': [936], 'used': [945], 'molecular': [950], 'diagnosis.': [951], 'Despite': [952], 'highlighted': [955], 'pro-tumor': [957], 'effects': [958], 'clusters,10': [961], 'what': [962], 'role': [963], 'they': [964], 'have': [965], 'unclear.': [969], 'Thus': [970], 'research': [972, 1006, 1067], 'understanding': [977], 'evaluating': [979], 'value.': [982], 'expanded': [986], 'application': [989], 'clusters,': [996], 'supply': [999], 'bridge': [1001], 'basic': [1005], 'practice.': [1009], 'supported': [1014], 'National': [1017], 'Natural': [1018], 'Science': [1019, 1044], 'Foundation': [1020], 'China': [1022], '(no.': [1023, 1028], '81572489)': [1024], '(to': [1025, 1030], 'QC)': [1026], '81502175)': [1029], 'BL).': [1031], 'authors': [1033, 1122, 1163, 1194], 'gratefully': [1035], 'acknowledge': [1036], 'technological': [1038], 'supports': [1039], 'Wuhan': [1041, 1083, 1104], 'YZY': [1042, 1058], 'Medical': [1043, 1059], 'Technology': [1046], 'Co.,': [1047], 'Ltd.': [1048], '(Wuhan,': [1049], 'China).': [1050], 'ISET': [1052], 'device': [1053], 'kindly': [1055], 'provided': [1056], 'Technological': [1060], 'Company.': [1061], 'animal': [1063], 'approved': [1069], 'Institutional': [1072, 1095], 'Animal': [1073], 'Care': [1074], 'Use': [1076], 'Committee': [1077], 'Renmin': [1080, 1101], 'Hospital': [1081, 1102], 'University.': [1084, 1105], 'Clinical': [1085], 'obtained': [1088], 'or': [1091, 1117, 1211], 'Review': [1096], 'Board-approved': [1097], 'protocols': [1098], 'Data': [1106], 'supporting': [1107, 1215], 'within': [1114], 'manuscript': [1116], 'available': [1118], 'corresponding': [1121, 1232], 'upon': [1123], 'reasonable': [1124], 'request.': [1125], 'Y.Q,': [1126, 1133, 1144], 'B.L,': [1127], 'Q.C': [1129, 1187], 'designed': [1130], 'Q.S,': [1134], 'G.D,': [1135], 'Y.L,': [1136, 1137], 'Z.Y,': [1138], 'Y.W': [1140], 'experiments.': [1143], 'H.Z,': [1145], 'Y.X,': [1146], 'S.H,': [1147], 'F.Y,': [1148], 'P.H,': [1149], 'L.G,': [1150], 'H.J,': [1151], 'W.W': [1153], 'collection': [1158], 'collation.': [1160], 'All': [1161], 'involved': [1165], 'analysis': [1168], 'interpretation': [1170], 'data.': [1172], 'Y.Q': [1173], 'G.D': [1175], 'wrote': [1176], 'paper,': [1178], 'co-authors.': [1184], 'B.L': [1185], 'reviewed': [1188], 'revised': [1190], 'manuscript.': [1192], 'declare': [1195], 'conflicts': [1198], 'interest': [1200], 'Please': [1201], 'note:': [1202], 'publisher': [1204], 'responsible': [1207], 'content': [1210], 'functionality': [1212], 'information': [1216], 'supplied': [1217], 'authors.': [1220], 'Any': [1221], 'queries': [1222], '(other': [1223], 'missing': [1225], 'content)': [1226], 'should': [1227], 'directed': [1229], 'author': [1233], 'article.': [1236]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3128128613', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2025-01-19T17:21:12.873252', 'created_date': '2021-02-15'}