Rab11-mediated post-Golgi transport of the sialyltransferase ST3GAL4 suggests a new mechanism for regulating glycosylation

Name: Work Video:
Duration: 3 min 30 s
Masato Kitano; Yasuhiko Kizuka; Tomoaki Sobajima; Miyako Nakano; Kazuki Nakajima; Ryo Misaki; Saki Itoyama; Yoichiro Harada; Akihiro Harada; Eiji Miyoshi; Naoyuki Taniguchi
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'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': '19K06546'}, {'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': '16811705'}, {'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': '20H03207'}, {'funder': 'https://openalex.org/F4320334896', 'funder_display_name': 'Japan Agency for Marine-Earth Science and Technology', 'award_id': '18070267'}, {'funder': 'https://openalex.org/F4320338075', 'funder_display_name': 'Core Research for Evolutional Science and Technology', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 70, 'referenced_works': ['https://openalex.org/W1182461782', 'https://openalex.org/W145329232', 'https://openalex.org/W1491957044', 'https://openalex.org/W1504897409', 'https://openalex.org/W1556859285', 'https://openalex.org/W1971176785', 'https://openalex.org/W1972805365', 'https://openalex.org/W1995555888', 'https://openalex.org/W2011970960', 'https://openalex.org/W2012925346', 'https://openalex.org/W2013388387', 'https://openalex.org/W2018042261', 'https://openalex.org/W2024191848', 'https://openalex.org/W2025590149', 'https://openalex.org/W2032576506', 'https://openalex.org/W2032880667', 'https://openalex.org/W2034912626', 'https://openalex.org/W2034949980', 'https://openalex.org/W2035307153', 'https://openalex.org/W2036289080', 'https://openalex.org/W2044971043', 'https://openalex.org/W2046300928', 'https://openalex.org/W2050903170', 'https://openalex.org/W2072204570', 'https://openalex.org/W2075630737', 'https://openalex.org/W2076247294', 'https://openalex.org/W2077613860', 'https://openalex.org/W2078093422', 'https://openalex.org/W2078201172', 'https://openalex.org/W2080472139', 'https://openalex.org/W2083427126', 'https://openalex.org/W2085530286', 'https://openalex.org/W2096913878', 'https://openalex.org/W2098643925', 'https://openalex.org/W2100360786', 'https://openalex.org/W2104089191', 'https://openalex.org/W2104974480', 'https://openalex.org/W2106658916', 'https://openalex.org/W2107625241', 'https://openalex.org/W2109927672', 'https://openalex.org/W2119914706', 'https://openalex.org/W2127063126', 'https://openalex.org/W2133535267', 'https://openalex.org/W2134402025', 'https://openalex.org/W2140334807', 'https://openalex.org/W2145206503', 'https://openalex.org/W2145536695', 'https://openalex.org/W2159825863', 'https://openalex.org/W2167279371', 'https://openalex.org/W2288122185', 'https://openalex.org/W2328548905', 'https://openalex.org/W2334764705', 'https://openalex.org/W2338225276', 'https://openalex.org/W2343807687', 'https://openalex.org/W2413236228', 'https://openalex.org/W2519269112', 'https://openalex.org/W2564847909', 'https://openalex.org/W2625835802', 'https://openalex.org/W2791492430', 'https://openalex.org/W2797185557', 'https://openalex.org/W2892229369', 'https://openalex.org/W2949385799', 'https://openalex.org/W2966318873', 'https://openalex.org/W2968256998', 'https://openalex.org/W2990553909', 'https://openalex.org/W2990901547', 'https://openalex.org/W2999794628', 'https://openalex.org/W3021221751', 'https://openalex.org/W3040006904', 'https://openalex.org/W3085556589'], 'related_works': ['https://openalex.org/W426835635', 'https://openalex.org/W2422762874', 'https://openalex.org/W2141589632', 'https://openalex.org/W2114834312', 'https://openalex.org/W2103136263', 'https://openalex.org/W2090078255', 'https://openalex.org/W2060113385', 'https://openalex.org/W200653673', 'https://openalex.org/W1967899691', 'https://openalex.org/W1965387885'], 'abstract_inverted_index': {'Glycosylation,': [0, 248], 'the': [1, 23, 34, 39, 48, 76, 90, 114, 138, 147, 154, 164, 170, 192, 197, 201, 212, 219, 249, 271, 282, 287, 296, 324, 338, 362, 386, 395, 402, 412, 418, 440, 445, 449, 460, 467, 500, 514, 556, 721, 773, 777, 789, 809, 851, 856, 859, 862, 870, 918, 950, 956, 961, 967, 971, 982, 991, 994, 1007, 1043, 1056, 1062, 1106, 1132, 1232, 1237, 1269, 1289, 1343, 1354, 1361, 1372, 1407, 1434, 1470, 1489, 1492, 1500, 1525, 1533, 1547, 1589, 1638, 1689, 1692, 1700, 1737, 1785, 1893, 1913, 1947, 1991, 2032, 2038, 2070, 2083, 2090, 2094, 2100, 2116, 2120, 2126, 2150, 2158, 2170, 2179, 2201, 2218, 2221, 2225, 2230, 2244, 2300, 2312, 2394, 2403, 2407, 2430, 2434, 2448, 2481, 2498, 2545, 2554, 2586, 2618, 2622, 2636, 2642, 2672, 2699, 2708, 2712, 2721, 2784, 2788, 2796, 2799, 2816, 2823, 2842, 2849, 2854, 2858, 2902, 2912, 2927, 2949, 2954, 2974, 2983, 2989, 3033, 3051, 3056, 3066, 3091, 3182, 3225, 3231, 3234, 3241, 3258, 3265, 3274, 3304, 3328, 3339, 3367, 3376, 3389, 3418, 3424, 3488, 3519, 3531, 3554, 3558, 3591, 3648, 3654, 3664, 3684, 3687, 3699, 3704, 3724, 3733, 3749, 3753, 3789, 3792, 3812, 3832, 3851, 3870, 3873, 3882, 3885, 3888, 3894, 3899, 3908, 3917, 3945, 3960, 3967, 3975, 3996, 3999, 4052, 4071, 4075, 4095, 4111, 4127, 4171, 4224, 4250, 4306, 4327, 4332], 'most': [2, 250, 501], 'common': [3, 251, 502, 778], 'posttranslational': [4, 252, 503], 'modification': [5, 253], 'of': [6, 17, 25, 93, 116, 120, 140, 149, 166, 172, 222, 245, 254, 265, 273, 341, 364, 368, 388, 397, 414, 420, 470, 493, 499, 516, 531, 594, 672, 720, 726, 741, 757, 780, 808, 834, 853, 873, 888, 920, 936, 952, 964, 970, 984, 996, 1010, 1042, 1049, 1061, 1064, 1102, 1109, 1150, 1159, 1188, 1239, 1325, 1346, 1356, 1363, 1374, 1414, 1437, 1448, 1491, 1495, 1549, 1615, 1644, 1662, 1702, 1720, 1739, 1758, 1781, 1787, 1863, 1916, 1946, 1952, 1990, 2035, 2086, 2102, 2152, 2203, 2220, 2232, 2246, 2252, 2314, 2367, 2375, 2393, 2406, 2432, 2450, 2480, 2484, 2497, 2547, 2553, 2624, 2639, 2688, 2745, 2775, 2786, 2826, 2845, 2904, 2956, 2977, 2985, 3032, 3036, 3069, 3093, 3099, 3126, 3153, 3174, 3184, 3217, 3237, 3250, 3260, 3330, 3341, 3379, 3391, 3414, 3426, 3451, 3491, 3521, 3544, 3561, 3603, 3650, 3666, 3726, 3735, 3755, 3785, 3794, 3816, 3834, 3853, 3884, 3887, 3898, 3907, 3959, 3977, 3979, 3998, 4018, 4026, 4054, 4074, 4100, 4114, 4168, 4228, 4268, 4308, 4329], 'proteins,': [7, 255, 1366, 2549], 'is': [8, 53, 129, 142, 153, 188, 215, 241, 256, 301, 377, 390, 401, 436, 463, 489, 497, 734, 744, 782, 794, 974, 998, 1286, 1451, 1510, 1515, 1552, 1582, 1600, 1642, 1752, 1852, 2063, 2143, 2155, 2161, 2207, 2239, 2264, 2293, 2487, 2574, 2692, 2738, 2958, 3024, 3074, 3157, 3204, 3244, 3360, 3546, 3640, 3712, 3728, 3748, 3818, 4002, 4028, 4041, 4163, 4293], 'a': [9, 66, 72, 110, 242, 257, 314, 320, 358, 490, 509, 717, 735, 978, 985, 1000, 1068, 1151, 1226, 1756, 1853, 2146, 2233, 2267, 2703, 2716, 2732, 2923, 2998, 3047, 3100, 3297, 3411, 3429, 3514, 3720, 4042, 4048, 4057], 'stepwise': [10, 258, 871], 'process': [11, 259], 'that': [12, 79, 105, 127, 133, 136, 157, 163, 227, 260, 327, 353, 375, 381, 384, 405, 411, 475, 1229, 1513, 1546, 1599, 1683, 1912, 2099, 2140, 2200, 2262, 2389, 2418, 2544, 2552, 2572, 2585, 2635, 2657, 2680, 2698, 2795, 2835, 2953, 3021, 3065, 3082, 3181, 3202, 3212, 3233, 3257, 3358, 3388, 3518, 3542, 3624, 3635, 3663, 3686, 3706, 3719, 3743, 3811, 3842, 3850, 3872, 3944, 3995, 4024, 4070, 4085, 4094, 4223, 4239, 4291], 'relies': [13, 261], 'on': [14, 159, 262, 407, 701, 3394, 3423, 3455], 'tight': [15, 263], 'regulation': [16, 264, 593, 1505, 3784], 'subcellular': [18, 266, 4112], 'glycosyltransferase': [19, 246, 267, 494, 973, 1258, 2238, 3721], 'location': [20, 268], 'to': [21, 218, 236, 269, 466, 484, 548, 784, 858, 976, 990, 1140, 1262, 1267, 1371, 1428, 1433, 1524, 1541, 1652, 1696, 1699, 2030, 2082, 2089, 2168, 2241, 2591, 2608, 2647, 2707, 2720, 3076, 3159, 3166, 3405, 3485, 3809, 3923, 3926, 3985, 4062, 4084, 4120, 4129], 'control': [22, 209, 270, 457, 1786, 2401, 2567, 2596, 2629, 2917, 3196, 3291, 3351, 3430, 3579, 3617, 3679, 3864, 3936, 3968, 3989, 4087, 4322], 'addition': [24, 272, 989, 1108, 2081], 'each': [26, 274, 1023, 1143, 1257, 3492], 'monosaccharide.': [27, 275], 'Glycosyltransferases': [28, 276], 'primarily': [29, 277], 'reside': [30, 278], 'and': [31, 38, 43, 55, 70, 83, 124, 203, 279, 286, 291, 303, 318, 331, 372, 451, 507, 518, 525, 545, 559, 572, 615, 641, 651, 674, 723, 806, 836, 867, 886, 913, 923, 966, 1019, 1161, 1185, 1193, 1223, 1235, 1292, 1330, 1352, 1376, 1417, 1424, 1474, 1519, 1532, 1649, 1668, 1691, 1743, 1761, 1769, 1777, 1926, 1998, 2024, 2184, 2193, 2325, 2369, 2379, 2458, 2493, 2528, 2597, 2612, 2630, 2667, 2711, 2743, 2772, 2798, 2806, 2832, 2837, 2909, 2919, 3053, 3058, 3133, 3145, 3164, 3301, 3303, 3316, 3324, 3333, 3336, 3343, 3573, 3580, 3590, 3661, 3779, 3848, 3896, 3937, 3969, 3990, 4046, 4097, 4203, 4284, 4288, 4298], 'function': [32, 280, 597, 887, 1651, 2744], 'in': [33, 75, 99, 109, 113, 191, 200, 204, 208, 281, 323, 347, 357, 361, 439, 448, 452, 456, 505, 512, 598, 633, 648, 669, 747, 788, 891, 955, 1047, 1138, 1231, 1272, 1288, 1300, 1406, 1554, 1588, 1602, 1665, 1686, 1722, 1745, 1763, 1784, 1921, 1933, 1948, 2027, 2037, 2069, 2093, 2105, 2115, 2157, 2182, 2186, 2210, 2224, 2235, 2299, 2317, 2327, 2371, 2410, 2425, 2438, 2443, 2532, 2562, 2576, 2579, 2641, 2664, 2783, 2848, 2857, 2867, 2901, 2911, 2926, 2931, 2939, 2948, 2960, 2991, 3001, 3004, 3026, 3040, 3061, 3071, 3086, 3095, 3170, 3187, 3193, 3206, 3214, 3264, 3277, 3327, 3338, 3346, 3362, 3375, 3459, 3530, 3537, 3549, 3563, 3642, 3659, 3674, 3690, 3698, 3709, 3760, 3782, 3820, 3845, 3859, 3876, 3935, 3950, 4016, 4051, 4079, 4086, 4233, 4261, 4296, 4300, 4317, 4331, 4337], 'endoplasmic': [35, 283, 774, 810, 1296], 'reticulum': [36, 284, 775, 1297], '(ER)': [37, 285], 'Golgi': [40, 202, 220, 288, 450, 468, 860, 957, 1233, 1291, 1364, 1410, 1693, 2850, 3266, 4172, 4193, 4207, 4252, 4333], 'apparatus;': [41, 289], 'whether': [42, 290, 1518, 2433], 'how': [44, 50, 56, 292, 298, 304, 729, 1520, 2153, 2862], 'they': [45, 293, 1650], 'traffic': [46, 294, 1667], 'beyond': [47, 295], 'Golgi,': [49, 297], 'this': [51, 299, 2166, 2237, 3014, 3825], 'trafficking': [52, 300, 1494, 1604, 1687, 2085, 4227], 'controlled,': [54, 302], 'it': [57, 305, 1908, 3993, 4257], 'impacts': [58, 306, 1349], 'glycosylation': [59, 307, 805, 1378, 1430, 1473, 1746, 2742, 3395], 'remain': [60, 308, 1506, 1955], 'unclear.': [61, 309, 1508], 'Our': [62, 102, 310, 350, 2227, 2254], 'previous': [63, 311, 1539, 2255, 2695], 'work': [64, 312], 'identified': [65, 313], 'connection': [67, 315], 'between': [68, 316, 1472, 1688, 3966, 3988], 'N-glycosylation': [69, 317, 743, 1548, 2142, 2159, 2263, 2436, 2469, 2479, 2500, 2573, 2649], 'Rab11,': [71, 94, 319, 342], 'key': [73, 321], 'player': [74, 322], 'post-Golgi': [77, 237, 325, 485, 1526, 4010, 4226], 'transport': [78, 326, 852, 1345, 1436, 1656, 1701, 4125], 'connects': [80, 328], 'recycling': [81, 329, 1447, 1606, 1759, 1765, 1891, 1895, 4130, 4301], 'endosomes': [82, 330, 1531, 1607, 1760, 4131, 4287, 4302], 'other': [84, 205, 332, 453, 1024, 1144, 3840], 'compartments.': [85, 333], 'To': [86, 334, 904, 1131, 2310, 2428, 2583, 2860, 2963, 3079, 3268, 3552, 3823, 4022], 'learn': [87, 335], 'more': [88, 336, 3270, 3503], 'about': [89, 337], 'specific': [91, 339, 1295], 'role': [92, 340, 511, 2531], 'we': [95, 161, 343, 409, 1544, 2017, 2097, 2177, 2198, 2319, 2446, 2870, 2920, 2966, 2996, 3089, 3280, 3482, 3516, 3566, 3717, 3830, 3931, 4034, 4221], 'knocked': [96, 344, 2321], 'down': [97, 345, 2322], 'Rab11': [98, 106, 150, 182, 223, 228, 346, 354, 398, 430, 471, 476, 1740, 1751, 1776, 1889, 1917, 1932, 1953, 2154, 2174, 2247, 2268, 2315, 2395, 2408, 2420, 2580, 2817, 3261, 3293, 3392, 4008, 4012, 4032, 4106, 4117, 4202], 'HeLa': [100, 348, 2188, 2328, 3582, 3761, 3939], 'cells.': [101, 349, 2189, 2427, 2582, 2962, 3028, 3171, 3208, 3551, 3644, 3822, 3940, 4235], 'findings': [103, 351, 2228, 3540], 'indicate': [104, 352, 4069], 'knockdown': [107, 185, 355, 433, 2331, 2818, 3259, 3393], 'results': [108, 356, 3556, 4068], 'dramatic': [111, 359], 'enhancement': [112, 360], 'sialylation': [115, 363, 2957, 3023, 3083, 3094, 3203, 3263, 3276, 3359, 3689, 3708], 'N-glycans.': [117, 365, 3421], 'Structural': [118, 366], 'analyses': [119, 367], 'glycans': [121, 369, 700, 925, 3127, 3176, 3186, 3321, 3335, 3381, 3526], 'using': [122, 370, 2257, 3827], 'lectins': [123, 371, 2876], 'LC-MS': [125, 373], 'revealed': [126, 374, 4238], 'α2,3-sialylation': [128, 232, 376, 480, 3543, 3560, 3725, 3754, 3793, 3875, 3947], 'selectively': [130, 378], 'enhanced,': [131, 379], 'suggesting': [132, 380, 2139, 2571, 2834, 2952, 3387, 4342], 'an': [134, 382, 785, 1016, 2028, 2387, 3247, 3497, 3696, 3903, 3913], 'α2,3-sialyltransferase': [135, 156, 383, 404, 2222], 'catalyzes': [137, 385, 1236], 'sialyation': [139, 387], 'glycoproteins': [141, 389, 517, 1551, 2104, 2578, 2640, 3070], 'activated': [143, 391, 3729, 4201], 'or': [144, 176, 392, 424, 1368, 2808, 2898, 3292, 3588, 3730, 3814], 'upregulated': [145, 393, 3731, 3858], 'as': [146, 394, 554, 1755, 2249, 2455, 3837, 3839, 4275], 'result': [148, 396], 'knockdown.': [151, 224, 399, 472, 4107], 'ST3GAL4': [152, 187, 235, 400, 435, 483, 2223, 3747, 3817, 3835, 3854, 3889, 3900, 3909, 3919, 3934, 3962, 3982, 4000, 4027, 4077, 4101, 4229, 4241, 4269, 4292, 4330], 'major': [155, 403, 510, 1001, 3419], 'acts': [158, 406], 'N-glycans;': [160, 408], 'demonstrated': [162, 410], 'localization': [165, 413, 995, 3815, 4113], 'ST3GAL4,': [167, 415, 3778], 'but': [168, 416, 2550, 2777, 3637, 3714], 'not': [169, 417, 1748, 2162, 2551, 2778, 3398, 3638, 3715, 3857, 4029, 4103], 'levels': [171, 419, 916, 2366, 2405, 3329, 3340, 3833, 3958, 3976, 4099], 'its': [173, 421, 1263, 1301, 3927, 4019, 4064], 'mRNA,': [174, 422], 'protein,': [175, 423, 2737, 3901], 'donor': [177, 425, 3655, 3700], 'substrate,': [178, 426], 'was': [179, 427, 2111, 2214, 2441, 2559, 2645, 2819, 3043, 3084, 3596, 3612, 3627, 3668, 3693, 3856, 3879, 3921, 3948, 4118, 4242, 4258, 4314, 4334], 'altered': [180, 428, 733, 1553, 2648, 2866, 3819], 'by': [181, 233, 429, 481, 869, 1053, 1067, 1111, 1619, 1860, 2130, 2145, 2172, 2217, 2266, 2383, 2462, 2614, 2815, 3046, 3097, 3168, 3177, 3246, 3285, 3296, 3310, 3598, 3695, 3732, 3881, 4031, 4105], 'depletion.': [183, 431], 'In': [184, 432, 629, 772, 948, 988, 1006, 1403, 1537, 1636, 2080, 2165, 3370], 'cells,': [186, 210, 434, 458, 519, 2212, 2402, 2445, 2869, 2918, 2951, 3088, 3279, 3364, 3565, 3992], 'densely': [189, 437], 'distributed': [190, 438, 4260], 'trans-Golgi': [193, 441], 'network,': [194, 442], 'compared': [195, 443, 2565, 2915, 3349, 3615, 3677, 3862, 4320], 'with': [196, 444, 1022, 1055, 1142, 2132, 2386, 2391, 2400, 2566, 2602, 2694, 2763, 2804, 2874, 2877, 2907, 2916, 2929, 2941, 2970, 2979, 2988, 2993, 3128, 3150, 3195, 3224, 3240, 3350, 3366, 3507, 3570, 3586, 3610, 3616, 3625, 3678, 3703, 3863, 4170, 4200, 4245, 4270, 4321], 'wider': [198, 446], 'distribution': [199, 447], 'peripheral': [206, 454], 'puncta': [207, 455], 'whereas': [211, 459, 3623], 'α2,6-sialyltransferase': [213, 461], 'ST6GAL1': [214, 462], 'predominantly': [216, 464], 'localized': [217, 465, 954, 1287, 2706, 2719, 4295], 'regardless': [221, 469], 'This': [225, 473, 2678, 3806, 3868], 'indicates': [226, 474, 2679], 'may': [229, 477], 'negatively': [230, 478], 'regulate': [231, 479, 1653, 2839], 'transporting': [234, 482], 'compartments': [238, 486, 1527], '(PGCs),': [239, 487, 1528], 'which': [240, 488, 2173, 2213, 2236, 2465, 2691, 2768, 3156], 'novel': [243, 491, 1152, 2250, 4191], 'mechanism': [244, 492], 'regulation.': [247, 495], 'Glycosylation': [496, 647, 668, 1101], 'one': [498, 3505], 'modifications': [504], 'eukaryotes': [506], 'has': [508, 1747, 1909], 'regulating': [513], 'functions': [515, 1762, 1951, 3787], 'including': [520, 639, 1529], 'folding,': [521], 'activity,': [522], 'cell': [523, 596, 617, 702, 1616, 1669, 2709, 3456], 'adhesion,': [524], 'communication': [526], '(1Varki': [527], 'A.': [528, 1146, 1179, 1247, 1380, 1440, 1580, 1707, 1711, 1812, 1836, 2061, 2291, 2346, 2753, 3119, 3445], 'Biological': [529], 'roles': [530, 725, 1915, 2034, 2245, 2313], 'glycans.Glycobiology.': [532], '2017;': [533, 1334, 1792], '27:': [534, 4215], '3-49Crossref': [535], 'PubMed': [536, 581, 605, 624, 659, 684, 710, 818, 845, 943, 1081, 1126, 1169, 1205, 1251, 1315, 1337, 1398, 1460, 1483, 1631, 1675, 1732, 1795, 1826, 1874, 1902, 2012, 2360, 2514, 2537, 2757, 3139, 3801, 4179], 'Scopus': [537, 582, 606, 625, 660, 685, 711, 819, 846, 900, 944, 1082, 1127, 1170, 1206, 1252, 1316, 1338, 1399, 1461, 1484, 1595, 1632, 1676, 1733, 1796, 1827, 1875, 1903, 2013, 2076, 2306, 2361, 2515, 2538, 2758, 3140, 3475, 3802, 4180, 4217], '(971)': [538], 'Google': [539, 584, 608, 627, 662, 687, 713, 821, 848, 902, 946, 1084, 1129, 1172, 1208, 1254, 1318, 1340, 1401, 1463, 1486, 1597, 1634, 1678, 1735, 1798, 1829, 1877, 1905, 1943, 2015, 2078, 2308, 2363, 2517, 2540, 2760, 3142, 3477, 3804, 4182, 4219], 'Scholar).': [540, 628, 714, 771, 849, 903, 947, 1130, 1255, 1341, 1402, 1487, 1635, 1679, 1906, 2079, 2309, 2364, 2541, 2761, 3143, 3805], 'Glycan': [541], 'structures': [542, 635, 731, 1066, 2864, 3284], 'are': [543, 732, 865, 958, 1522, 1684, 1694, 1919, 1963, 2684, 2802, 2865, 3397, 3402, 3843, 3983], 'diverse': [544], 'dynamically': [546], 'change': [547], 'enable': [549], 'complex': [550, 1157, 1228, 1412, 2779, 2805], 'multicellular': [551], 'systems': [552], 'such': [553, 2454, 4274], 'immunity,': [555], 'nervous': [557], 'system,': [558], 'development': [560], '(2Moremen': [561], 'K.W.': [562, 927], 'Tiemeyer': [563], 'M.': [564, 613, 690, 754, 877, 1034, 1091, 1181, 1566, 1568, 1834, 1844, 1886, 2047, 2049, 2277, 2279, 2520, 2726, 2730, 3441, 3447, 4141], 'Nairn': [565], 'A.V.': [566], 'Vertebrate': [567], 'protein': [568, 1190, 1455, 1586, 1815, 2067, 2297, 2349, 2556, 3910, 3920, 3963, 4001, 4043, 4050, 4078, 4098, 4198], 'glycosylation:': [569], 'Diversity,': [570], 'synthesis': [571, 935, 1238, 3978, 4044], 'function.Nat.': [573], 'Rev.': [574, 600, 619, 654, 1671], 'Mol.': [575, 840, 895, 1937], 'Cell': [576, 813, 1332, 1477, 1621, 1727, 1821, 1897, 2355], 'Biol.': [577, 814, 939, 1071, 1116, 1195, 1305, 1333, 1388, 1479, 1622, 1790, 1822, 1898, 2002, 2356, 2504, 4174, 4212], '2012;': [578, 1118, 1390], '13:': [579], '448-462Crossref': [580], '(1008)': [583], 'Scholar,': [585, 609, 663, 688, 822, 1085, 1173, 1209, 1319, 1464, 1799, 1830, 1878, 2518, 4183], '3MacAuley': [586], 'M.S.': [587], 'Crocker': [588], 'P.R.': [589], 'Paulson': [590], 'J.C.': [591], 'Siglec-mediated': [592], 'immune': [595], 'disease.Nat.': [599], 'Immunol.': [601], '2014;': [602, 1623, 2004], '14:': [603, 2535], '653-666Crossref': [604], '(536)': [607], '4Kleene': [610], 'R.': [611, 803, 1038, 1975, 3443, 4187], 'Schachner': [612], 'Glycans': [614], 'neural': [616], 'interactions.Nat.': [618], 'Neurosci.': [620], '2004;': [621, 4176], '5:': [622], '195-208Crossref': [623], '(417)': [626], 'addition,': [630, 1404], 'undesirable': [631], 'changes': [632, 2181, 2925], 'glycan': [634, 730, 1004, 1018, 1270, 1350, 1498, 3283, 3452, 3493, 3506], 'cause': [636, 3912], 'various': [637, 739, 874, 2577, 2875], 'diseases,': [638], 'cancer': [640, 1927], 'diabetes': [642], '(5Pinho': [643], 'S.S.': [644], 'Reis': [645], 'C.A.': [646], 'cancer:': [649], 'Mechanisms': [650], 'clinical': [652], 'implications.Nat.': [653], 'Cancer.': [655], '2015;': [656, 1592, 1940, 2073, 2303], '15:': [657, 941, 1167, 4177], '540-555Crossref': [658], '(1331)': [661], '6Ohtsubo': [664], 'K.': [665, 694, 1036, 1148, 1175, 1709], 'Marth': [666], 'J.D.': [667], 'cellular': [670, 1328], 'mechanisms': [671, 1501, 2171], 'health': [673, 835], 'disease.Cell.': [675], '2006;': [676, 1197, 1307, 1457, 3136], '126:': [677], '855-867Abstract': [678], 'Full': [679, 681, 1076, 1078, 1121, 1123, 1200, 1202, 1310, 1312, 1393, 1395, 1626, 1628, 1869, 1871, 2007, 2009, 2509, 2511, 3470, 3472], 'Text': [680, 682, 1077, 1079, 1122, 1124, 1201, 1203, 1311, 1313, 1394, 1396, 1627, 1629, 1870, 1872, 2008, 2010, 2510, 2512, 3471, 3473], 'PDF': [683, 1080, 1125, 1204, 1314, 1397, 1630, 1873, 2011, 2513, 3474], '(1937)': [686], '7Takahashi': [689], 'Kizuka': [691, 827, 882], 'Y.': [692, 824, 826, 828, 879, 883, 1028, 1576, 2057, 2287, 2474, 3772], 'Ohtsubo': [693], 'Gu': [695, 2477, 3775], 'J.': [696, 839, 894, 1611, 1705, 1936, 1971, 2478, 2728, 3770, 3776, 3797], 'Taniguchi': [697, 751, 829, 880, 1039], 'N.': [698, 752, 799, 830, 881, 1040, 1570, 1987, 2051, 2281, 4145], 'Disease-associated': [699], 'surface': [703, 1617, 2710], 'proteins.Mol.': [704], 'Aspects': [705], 'Med.': [706, 1939], '2016;': [707, 815, 1480], '51:': [708], '56-70Crossref': [709], '(48)': [712, 1171, 1734], 'Therefore,': [715, 1256], 'for': [716, 796, 960, 981, 1003, 1453, 1497, 1503, 1584, 1856, 2065, 2295, 2489, 2502, 2740, 2822, 3131, 3273, 3417, 3657, 3723, 3752, 3791, 4056, 4123, 4165, 4249, 4272], 'further': [718, 2793, 3019, 3080, 3200, 3408], 'understanding': [719], 'physiological': [722, 1950, 2033], 'pathological': [724, 1914], 'glycans,': [727, 1011], 'elucidating': [728], 'pivotal': [736], 'issue.': [737], 'Among': [738], 'types': [740, 2774], 'glycosylation,': [742], 'highly': [745], 'conserved': [746, 1408], 'mammals': [748], '(8Stanley': [749], 'P.': [750, 1466, 1977, 2524, 4134, 4155], 'Aebi': [753], 'N-glycans.in:': [755], 'Essentials': [756], 'Glycobiology': [758], '[Internet].': [759], '3rd': [760], 'Ed.': [761], 'Cold': [762, 767], 'Spring': [763, 768], 'Harbor': [764], 'Laboratory': [765], 'Press,': [766], 'Harbor,': [769], 'NY2017Google': [770], '(ER),': [776], 'form': [779, 1136, 1225, 2705, 2718, 2825], 'oligosaccharide': [781], 'attached': [783, 863], 'asparagine': [786], 'residue': [787], 'consensus': [790], 'sequence': [791], '(Asn-X-Ser/Thr,': [792], 'X': [793], 'except': [795], 'Pro)': [797], '(9Cherepanova': [798], 'Shrimal': [800], 'S.': [801, 1026, 1030, 1246, 1442, 1572, 1715, 1717, 1803, 1882, 1884, 1967, 2053, 2283, 2337, 2752], 'Gilmore': [802], 'N-linked': [804], 'homeostasis': [807], 'reticulum.Curr.': [811], 'Opin.': [812], '41:': [816], '57-65Crossref': [817], '(110)': [820], '10Harada': [823], 'Ohkawa': [825], 'Oligosaccharyltransferase:': [831], 'A': [832, 1779, 3010, 3737, 4190], 'gatekeeper': [833], 'tumor': [837, 1220], 'progression.Int.': [838, 1935], 'Sci.': [841, 896, 1244, 2750], '2019;': [842, 940], '20:': [843], '6074Crossref': [844], '(21)': [847, 901], 'During': [850], 'proteins': [854, 1416, 1618, 1682, 1741, 1918, 1954, 2088, 2248, 2316, 2453, 2527, 2594, 2906, 3213, 3458], 'from': [855, 2595, 2628, 3290, 3428, 3578, 3607, 4126], 'ER': [857, 1690, 2722], 'apparatus,': [861], 'N-glycans': [864, 2127, 2183, 2611, 2776, 3287, 3345, 3427, 3545, 3562, 3727, 3759], 'processed': [866], 'modified': [868, 2803], 'action': [872], 'glycosyltransferases': [875, 889, 909, 953, 997, 1013, 1135, 1347, 1375, 1438, 1450, 1496, 1521, 1703, 2185], '(11Nagae': [876], 'Yamaguchi': [878], '3D': [884], 'structure': [885, 3453], 'involved': [890, 1601, 1685, 1920, 2156, 3844, 4015], 'N-glycan': [892, 2846, 2863, 3305, 3846], 'maturation.Int.': [893], '2020;': [897, 3798], '21:': [898], '1-23Crossref': [899], 'date,': [905], 'approximately': [906], '180': [907], 'human': [908, 1189], 'have': [910, 2466, 3436], 'been': [911, 1749, 1910, 3438], 'identified,': [912], 'their': [914, 1418, 1504, 2529, 3783], 'expression': [915, 968, 992, 1046, 1355, 2404, 2492, 3813, 3852, 3886, 3929], 'impact': [917], 'biosynthesis': [919, 983, 1063, 1351, 2847, 3847], 'protein-,': [921], 'cell-type-,': [922], 'disease-specific': [924], '(12Moremen': [926], 'Haltiwanger': [928], 'R.S.': [929], 'Emerging': [930], 'structural': [931, 962], 'insights': [932], 'into': [933], 'glycosyltransferase-mediated': [934], 'glycans.Nat.': [937], 'Chem.': [938, 1072, 1117, 1196, 1306, 1389, 2003, 2505], '853-864Crossref': [942], '(53)': [945], 'particular,': [949], 'actions': [951], 'responsible': [959, 972, 1502, 3722], 'diversity': [963], 'N-glycans,': [965, 2781, 2810], 'level': [969, 3092, 3183, 3665, 3895, 4328], 'considered': [975, 3984], 'be': [977, 1260, 1697, 2655, 3986, 4014, 4121, 4231], 'primary': [979, 1854], 'factor': [980, 1002], 'certain': [986, 4058], 'glycan.': [987], 'level,': [993, 3930], 'also': [999, 1426, 2654, 3044, 3210, 3220, 3646, 4003, 4259], 'biosynthesis.': [1005], 'biosynthetic': [1008], 'pathways': [1009, 3396], 'Golgi-localized': [1012], 'often': [1014], 'share': [1015], 'acceptor': [1017], 'can': [1020], 'compete': [1021], '(13Koyota': [1025], 'Ikeda': [1027], 'Miyagawa': [1029], 'Ihara': [1031], 'H.': [1032, 1177, 1808, 2342], 'Koma': [1033], 'Honke': [1035], 'Shirakura': [1037], 'Down-regulation': [1041], 'α-Gal': [1044], 'epitope': [1045], 'N-Glycans': [1048], 'swine': [1050], 'endothelial': [1051], 'cells': [1052, 1273, 2329, 2377, 2564, 2568, 2599, 2632, 2644, 2933, 3006, 3042, 3073, 3096, 3147, 3189, 3197, 3219, 3239, 3295, 3348, 3352, 3583, 3609, 3618, 3660, 3676, 3680, 3692, 3711, 3762, 3861, 3865, 3878, 3953, 3971, 4081, 4088, 4319, 4323, 4339], 'transfection': [1054], 'N-Acetylglucosaminyltransferase': [1057], 'III': [1058], 'gene:': [1059], 'Modulation': [1060], 'terminal': [1065, 2975, 3022], 'bisecting': [1069], 'GlcNAc.J.': [1070], '2001;': [1073], '276:': [1074], '32867-32874Abstract': [1075], '(44)': [1083], '14Tran': [1086], 'D.T.': [1087], 'Lim': [1088], 'J.M.': [1089, 3109], 'Liu': [1090], 'Stalnaker': [1092], 'S.H.': [1093], 'Wells': [1094], 'L.': [1095], 'Ten': [1096], 'Hagen': [1097], 'K.G.': [1098], 'Live': [1099], 'D.': [1100, 1468], 'α-dystroglycan:': [1103], 'O-mannosylation': [1104], 'influences': [1105], 'subsequent': [1107], 'GalNAc': [1110], 'UDP-GalNAc': [1112], 'polypeptide': [1113], 'N-': [1114], 'acetylgalactosaminyltransferases.J.': [1115], '287:': [1119, 1391], '20967-20974Abstract': [1120], '(15)': [1128], 'contrary,': [1133], 'some': [1134, 2905], 'heterocomplexes': [1137], 'order': [1139], 'cooperate': [1141], '(15Seko': [1145], 'Yamashita': [1147], 'Characterization': [1149], 'galactose': [1153], 'β1,3-N-acetylglucosaminyltransferase': [1154], '(β3Gn-T8):': [1155], 'The': [1156, 1218, 1282, 1813, 1849, 2347, 2365, 2812, 3029, 3172, 3601, 3956, 4067], 'formation': [1158, 1771], 'β3Gn-T2': [1160], 'β3Gn-T8': [1162], 'enhances': [1163, 3262], 'enzymatic': [1164], 'activity.Glycobiology.': [1165], '2005;': [1166], '943-951Crossref': [1168], '16Akasaka-Manya': [1174], 'Manya': [1176], 'Nakajima': [1178], 'Kawakita': [1180], 'Endo': [1182], 'T.': [1183, 1560, 1564, 1609, 1713, 1801, 1806, 1929, 2041, 2045, 2271, 2275, 2335, 2340, 2472, 2476, 3766, 3774], 'Physical': [1184], 'functional': [1186, 4166], 'association': [1187, 4167], 'O-mannosyltransferases': [1191], '1': [1192, 2461, 2627, 2660, 3039, 3595, 3606, 3758], '2.J.': [1194], '281:': [1198, 1308], '19339-19345Abstract': [1199], '(82)': [1207], '17McCormick': [1210], 'C.': [1211, 1832, 3768], 'Duncan': [1212, 4186], 'G.': [1213, 1969], 'Goutsos': [1214], 'K.T.': [1215], 'Tufaro': [1216], 'F.': [1217, 3764], 'putative': [1219], 'suppressors': [1221], 'EXT1': [1222], 'EXT2': [1224], 'stable': [1227], 'accumulates': [1230], 'apparatus': [1234, 2851], 'heparan': [1240], 'sulfate.Proc.': [1241], 'Natl.': [1242, 2748], 'Acad.': [1243, 2749], 'U.': [1245, 2751], '2000;': [1248], '97:': [1249], '668-673Crossref': [1250], '(356)': [1253], 'should': [1259, 2653], 'trafficked': [1261, 1523, 2240], 'own': [1264], 'appropriate': [1265, 1493], 'place': [1266], 'maintain': [1268], 'profiles': [1271], '(18Zhao': [1274], 'W.': [1275, 1985], 'Chen': [1276], 'T.L.L.': [1277], 'Vertel': [1278], 'B.M.': [1279, 4149], 'Colley': [1280, 1322], 'K.J.': [1281, 1323], 'CMP-sialic': [1283], 'acid': [1284, 2981, 3162, 3652], 'transporter': [1285], 'medial-trans': [1290], 'possesses': [1293], 'two': [1294, 2372, 2662, 2682], 'export': [1298, 4194], 'motifs': [1299], 'carboxyl-terminal': [1302], 'cytoplasmic': [1303], 'tail.J.': [1304], '31106-31118Abstract': [1309], '(36)': [1317], '19Bhide': [1320], 'G.P.': [1321], 'Sialylation': [1324], 'N-glycans:': [1326], 'Mechanism,': [1327], 'compartmentalization': [1329], 'function.Histochem.': [1331], '147:': [1335], '149-174Crossref': [1336], '(120)': [1339], 'Indeed,': [1342], 'abnormal': [1344, 2141, 2435, 2592], 'significantly': [1348, 4315, 4335], 'causes': [1353], 'aberrant': [1357, 1429], 'glycans.': [1358], 'For': [1359], 'example,': [1360], 'deletion': [1362], 'scaffold': [1365], 'Giantin': [1367], 'GM130,': [1369], 'leads': [1370], 'mislocalization': [1373], 'impaired': [1377, 1435, 2084, 3248, 4232], '(20Petrosyan': [1379], 'Ali': [1381], 'M.F.': [1382], 'Cheng': [1383], 'P.W.': [1384], 'Glycosyltransferase-specific': [1385], 'Golgi-targeting': [1386], 'mechanisms.J.': [1387], '37621-37627Abstract': [1392], '(33)': [1400, 2759], 'defects': [1405], 'oligomeric': [1409], '(COG)': [1411], 'comprised': [1413], 'COG': [1415, 1445], 'interacting': [1419], 'partners': [1420], '(Rab': [1421], 'GTPases,': [1422], 'golgins,': [1423], 'SNAREs)': [1425], 'lead': [1427], 'probably': [1431], 'due': [1432, 2590, 2646, 3075, 3925], '(21Shestakova': [1439], 'Zolov': [1441], 'Lupashin': [1443], 'V.': [1444], 'complex-mediated': [1446], 'golgi': [1449], 'essential': [1452, 2488], 'normal': [1454], 'glycosylation.Traffic.': [1456], '7:': [1458], '191-204Crossref': [1459], '(118)': [1462], '22Fisher': [1465], 'Ungar': [1467], 'Bridging': [1469], 'gap': [1471], 'vesicle': [1475], 'traffic.Front.': [1476], 'Dev.': [1478], '4:': [1481, 1593, 1941, 2074, 2304], '1-12Crossref': [1482], '(34)': [1485, 1797], 'Despite': [1488], 'importance': [1490], 'expression,': [1499], 'largely': [1507], 'It': [1509, 2652], 'particularly': [1511, 2205, 2944, 4299], 'noteworthy': [1512], 'little': [1514], 'known': [1516], 'concerning': [1517], 'early/late/recycling': [1530], 'plasma': [1534, 4209], 'membrane': [1535, 1655, 1666, 1725, 2092, 2526, 3457, 4124, 4210], '(PM).': [1536], 'our': [1538, 1542], 'report,': [1540], 'surprise,': [1543], 'found': [1545, 2199, 2437, 2543, 2997, 3211, 3325, 3517, 3662, 3849], 'several': [1550, 2103, 3745], 'mutant': [1555, 2117], 'mice': [1556, 1962, 2023, 2259, 2440], 'lacking': [1557], 'Rab11a': [1558, 1581, 1959, 1993, 2020, 2036, 2062, 2147, 2292, 2324, 2368, 2836], '(23Sobajima': [1559, 2040, 2270], 'Yoshimura': [1561, 1802, 2042, 2272, 2336], 'S.I.': [1562, 2043, 2273], 'Iwano': [1563, 2044, 2274], 'Kunii': [1565, 2046, 2276], 'Watanabe': [1567, 2048, 2278], 'Atik': [1569, 2050, 2280], 'Mushiake': [1571, 2052, 2282], 'Morii': [1573, 2054, 2284], 'E.': [1574, 1578, 1613, 1775, 1810, 1973, 2055, 2059, 2285, 2289, 2344], 'Koyama': [1575, 2056, 2286], 'Miyoshi': [1577, 1809, 2058, 2288, 2343], 'Harada': [1579, 1811, 2060, 2290, 2345], 'required': [1583, 2064, 2294, 2739, 4122], 'apical': [1585, 2066, 2087, 2091, 2296], 'localisation': [1587, 2068, 2298], 'intestine.Biol.': [1590, 2071, 2301], 'Open.': [1591, 2072, 2302], '86-94Crossref': [1594, 2075, 2305], '(62)': [1596, 2077, 2307], 'Scholar)': [1598, 3478], 'vesicular': [1603, 1788], 'via': [1605, 3788], '(24Welz': [1608], 'Wellbourne-Wood': [1610], 'Kerkhoff': [1612], 'Orchestration': [1614], 'Rab11.Trends': [1620], '24:': [1624], '407-415Abstract': [1625], '(168)': [1633], 'mammals,': [1637], 'Rab': [1639, 1663, 1681], 'GTPase': [1640], 'family': [1641], 'composed': [1643], 'at': [1645, 2841], 'least': [1646], '60': [1647], 'members,': [1648], 'intracellular': [1654, 1764, 1818, 2352], '(25Hutagalung': [1657], 'A.H.': [1658], 'Novick': [1659], 'P.J.': [1660, 4147], 'Role': [1661], 'GTPases': [1664], 'physiology.Physiol.': [1670], '2011;': [1672, 3467, 4214], '91:': [1673], '119-149Crossref': [1674], '(970)': [1677], 'Although': [1680, 1907], 'likely': [1695, 2215], 'committed': [1698], '(26Yamane': [1704], 'Kubo': [1706], 'Nakayama': [1708], 'Yuba-Kubo': [1710], 'Katsuno': [1712], 'Tsukita': [1714, 1716], 'Functional': [1718], 'involvement': [1719, 1738], 'TMF/ARA160': [1721], 'Rab6-dependent': [1723], 'retrograde': [1724], 'traffic.Exp.': [1726], 'Res.': [1728], '2007;': [1729, 2754], '313:': [1730], '3472-3485Crossref': [1731], 'Scholar),': [1736, 1944, 2016, 4220], '(Rab11a': [1742], 'Rab11b)': [1744], 'elucidated.': [1750], 'frequently': [1753], 'used': [1754, 2025], 'marker': [1757, 4248], 'pathways,': [1766], 'cholesterol': [1767, 1819, 2353], 'transport,': [1768], 'autophagosome': [1770, 1857], '(27Campa': [1772], 'C.C.': [1773], 'Hirsch': [1774], 'phosphoinositides:': [1778], 'synergy': [1780], 'signal': [1782, 4195], 'transducers': [1783], 'trafficking.Adv.': [1789], 'Regul.': [1791], '63:': [1793], '132-139Crossref': [1794], '28Sobajima': [1800], 'ichiro': [1804, 2338], 'Maeda': [1805, 2339], 'Miyata': [1807, 2341], 'Rab11-binding': [1814, 2348], 'RELCH/KIAA1468': [1816, 2350], 'controls': [1817, 2351], 'distribution.J.': [1820, 2354], '2018;': [1823, 1866, 2357], '217:': [1824, 2358], '1777-1796Crossref': [1825, 2359], '(19)': [1828, 2362], '29Puri': [1831], 'Vicinanza': [1833], 'Ashkenazi': [1835], 'Gratian': [1837], 'M.J.': [1838, 3117], 'Zhang': [1839], 'Q.': [1840], 'Bento': [1841], 'C.F.': [1842], 'Renna': [1843], 'Menzies': [1845], 'F.M.': [1846], 'Rubinsztein': [1847], 'D.C.': [1848], 'RAB11A-positive': [1850], 'compartment': [1851], 'platform': [1855], 'assembly': [1858], 'mediated': [1859], 'WIPI2': [1861], 'recognition': [1862], 'PI3P-RAB11A.Dev.': [1864], 'Cell.': [1865, 1938, 3465, 4175, 4213], '45:': [1867], '114-131.e8Abstract': [1868], '(83)': [1876], '30Ullrich': [1879], 'O.': [1880], 'Reinsch': [1881], 'Urbé': [1883], 'Zerial': [1885], 'Parton': [1887], 'R.G.': [1888], 'regulates': [1890, 2175, 4009], 'through': [1892], 'pericentriolar': [1894], 'endosome.J.': [1896], '1996;': [1899], '135:': [1900], '913-924Crossref': [1901], '(1035)': [1904], 'reported': [1911], "Alzheimer's": [1922], 'disease,': [1923, 1925], "Huntington's": [1924], '(31Bhuin': [1928], 'Roy': [1930], 'J.K.': [1931], 'disease': [1934], '1-8PubMed': [1942], 'details': [1945], 'vivo': [1949], 'poorly': [1956], 'understood.': [1957], 'Since': [1958, 3916, 4116], 'systemic': [1960], 'knockout': [1961, 2021, 3739], 'embryonically': [1964], 'lethal': [1965], '(32Yu': [1966], 'Yehia': [1968], 'Wang': [1970, 3771], 'Stypulkowski': [1972], 'Sakamori': [1974], 'Jiang': [1976], 'Hernandez-Enriquez': [1978], 'B.': [1979, 2522], 'Tran': [1980], 'T.S.': [1981], 'Bonder': [1982], 'E.M.': [1983], 'Guo': [1984], 'Gao': [1986], 'Global': [1988], 'ablation': [1989], 'mouse': [1992], 'gene': [1994], 'impairs': [1995], 'early': [1996, 2855], 'embryogenesis': [1997], 'matrix': [1999], 'metalloproteinase': [2000], 'secretion.J.': [2001], '289:': [2005], '32030-32043Abstract': [2006], '(27)': [2014], 'generated': [2018], 'intestine-specific': [2019], '(IKO)': [2022], 'them': [2026], 'attempt': [2029], 'elucidate': [2031, 2311], 'gut': [2039], 'IKO': [2095, 2258], 'mice,': [2096], 'discovered': [2098], 'mobility': [2101, 2121, 2449, 2546, 2587, 2623, 2638, 2813, 3030, 3068], 'SDS-polyacrylamide': [2106], 'gel': [2107, 2110], 'electrophoresis': [2108], '(SDS-PAGE)': [2109], 'commonly': [2112], 'shifted': [2113], 'up': [2114], 'mice.': [2118], 'Furthermore,': [2119, 4305], 'shifts': [2122, 2588], 'were': [2123, 2128, 2381, 2414, 2422, 2589, 2600, 2946, 3148, 3288, 3307, 3382, 3483, 3527, 3584, 3964, 4082, 4102], 'canceled': [2124, 3013, 3045], 'when': [2125], 'removed': [2129], 'treatment': [2131, 2675, 3012, 3049, 3300], 'peptide': [2133, 2603], 'N-glycosidase': [2134, 2604], 'F': [2135, 2605, 2620, 2674, 3299], '(PNGase': [2136, 2606], 'F),': [2137], 'strongly': [2138, 2260], 'caused': [2144, 2216, 3245, 3694, 3880], 'deficiency.': [2148], 'However,': [2149, 4006], 'issue': [2151, 2431], 'pathway': [2160, 2234], 'completely': [2163], 'clear.': [2164], 'study,': [2167], 'reveal': [2169], 'N-glycosylation,': [2176, 2318, 2593], 'investigated': [2178], 'detailed': [2180], 'Rab11-knockdown': [2187, 2211], 'Using': [2190], 'lectin': [2191, 2872, 2968, 3227, 3243], 'blotting': [2192, 2385, 2873, 2969], 'mass': [2194], 'spectrometry': [2195], '(MS)': [2196], 'analyses,': [2197], 'extent': [2202], 'sialylation,': [2204, 3658], 'α2,3-sialylation,': [2206], 'strikingly': [2208, 3528], 'increased': [2209, 3192, 3222, 3235, 3614, 3673, 4336], 'accumulation': [2219], 'Golgi.': [2226], 'suggest': [2229], 'existence': [2231], 'PGCs,': [2242, 4273], 'highlighting': [2243], 'regulators': [2251], 'N-glycosylation.': [2253], 'study': [2256, 3740], 'suggested': [2261], 'dysregulated': [2265], 'deficiency': [2269], 'stably': [2320], 'both': [2323, 2392, 2411, 2419, 2668], 'Rab11b': [2326, 2370, 2838], '(double': [2330], '(DKD)': [2332], 'cells)': [2333], '(28Sobajima': [2334], 'representative': [2373], 'clones': [2374, 2413], 'DKD': [2376, 2412, 2444, 2563, 2581, 2598, 2631, 2643, 2868, 2913, 2932, 2950, 2961, 3005, 3027, 3041, 3072, 3087, 3146, 3188, 3207, 3218, 3238, 3278, 3294, 3347, 3363, 3532, 3550, 3564, 3581, 3608, 3643, 3675, 3691, 3710, 3821, 3860, 3877, 3938, 3952, 3970, 3991, 4080, 4234, 4318, 4338], '(#22': [2378], '#27)': [2380], 'analyzed': [2382, 2613, 3282, 3309, 3597], 'western': [2384, 2463, 2615, 2665, 3599], 'antibody': [2388], 'reacts': [2390], 'isoforms': [2396, 2409, 2421], '(Fig.': [2397, 2569, 2650, 2676, 2791, 2829, 2893, 2934, 3007, 3016, 3198, 3228, 3312, 3353, 3384, 3479, 3511, 3534, 3619, 3630, 3681, 3866, 3954, 3972, 4089, 4255, 4264, 4303, 4312, 4324, 4340], '1A).': [2398], 'Compared': [2399], 'essentially': [2415], 'negligible,': [2416], 'confirming': [2417, 2794, 3020, 3634], 'successfully': [2423, 3486], 'silenced': [2424], 'these': [2426, 2548, 2681], 'examine': [2429], 'Rab11-deficient': [2439], 'recapitulated': [2442], 'examined': [2447, 3893, 4110], 'heavily': [2451], 'N-glycosylated': [2452], 'Lamp1,': [2456], 'Lamp2,': [2457], 'integrin': [2459, 2486, 2491, 2625, 2658, 2689, 2746, 2827, 3037, 3593, 3604, 3756], 'beta': [2460, 2626, 2659, 3038, 3594, 3605, 3757], 'blotting,': [2464, 2666], 'over': [2467], '10': [2468], 'sites': [2470], '(33Isaji': [2471], 'Sato': [2473], 'Fukuda': [2475, 3773], 'I-like': [2482], 'domain': [2483], 'β1': [2485, 2490], 'biological': [2494, 3786], 'function.': [2495], 'Identification': [2496, 3450], 'minimal': [2499], 'requirement': [2501], 'α5β1.J.': [2503], '2009;': [2506], '284:': [2507], '12207-12216Abstract': [2508], '(76)': [2516], '34Schwake': [2519], 'Schröder': [2521], 'Saftig': [2523], 'Lysosomal': [2525], 'central': [2530], 'physiology.Traffic.': [2533], '2013;': [2534], '739-748Crossref': [2536], '(121)': [2539], 'We': [2542, 2895, 3209, 3318, 3407, 3645, 3891, 3941, 4108], 'non-N-glycosylated': [2555], 'Lamin': [2557], 'B,': [2558], 'markedly': [2560], 'slower': [2561, 2637], '1B),': [2570], 'disturbed': [2575], 'confirm': [2584, 2964, 3081, 4023], 'treated': [2601], 'F)': [2607], 'remove': [2609], 'all': [2610], 'blotting.': [2616, 3600], 'After': [2617], 'PNGase': [2619, 2673, 3298], 'treatment,': [2621], 'converged,': [2633], 'demonstrating': [2634], '1C).': [2651, 2677], 'noted': [2656], 'showed': [2661, 3180, 3742, 4290], 'bands': [2663, 2683], 'forms': [2669, 2687, 2801], 'converged': [2670], 'after': [2671], 'differentially': [2685], 'glycosylated': [2686], 'beta1,': [2690], 'consistent': [2693, 3365], 'reports': [2696], 'showing': [2697, 3201, 3357, 3557], 'upper': [2700, 3034], 'band': [2701, 2714, 2790, 3035], 'represents': [2702, 2715], 'mature': [2704, 2797, 2824], 'lower': [2713, 2789], 'premature': [2717], '(35Shen': [2723], 'X.': [2724], 'Hong': [2725], 'Moss': [2727], 'Vaughan': [2729], 'BIG1,': [2731], 'brefeldin': [2733], 'A-inhibited': [2734], 'guanine': [2735], 'nucleotide-exchange': [2736], 'correct': [2741], 'b1?.Proc.': [2747], '104:': [2755], '1230-1235Crossref': [2756], 'Treatment': [2762], 'endoglycosidase': [2764], 'H': [2765], '(Endo': [2766], 'H),': [2767], 'cleaves': [2769], 'only': [2770, 2787, 2820, 2922], 'oligomannose': [2771, 2807, 2882], 'hybrid': [2773, 2809], 'type': [2780], 'resulted': [2782], 'downshift': [2785], '1D),': [2792], 'immature': [2800], 'respectively.': [2811], 'shift': [2814, 3031], 'observed': [2821, 2896, 2921, 2947, 3383, 3949], 'beta1': [2828], '1,': [2830], 'B': [2831, 3461], 'D),': [2833], 'steps': [2840], 'late': [2843], 'stage': [2844, 2856], 'rather': [2852, 3523, 3670], 'than': [2853, 3504, 3524, 3671], 'ER.': [2859], 'investigate': [2861], 'conducted': [2871], 'different': [2878, 3508], 'binding': [2879, 2984], 'preferences': [2880], '(ConA,': [2881], 'glycans;': [2883], 'PhoSL,': [2884], 'core': [2885], 'fucose;': [2886], 'L4-PHA,': [2887], 'β1,6-GlcNAc;': [2888], 'SSA,': [2889], 'α2,6Sia;': [2890], 'MAM,': [2891, 2945], 'α2,3Sia)': [2892], '2A).': [2894, 2935], 'slight': [2897], 'moderate': [2899], 'increases': [2900, 2938, 2990, 3326], 'reactivity': [2903, 2928, 2940, 2992, 3003, 3223, 3236, 3602], 'ConA': [2908], 'L4-PHA': [2910], 'samples': [2914, 3533], 'few': [2924], 'PhoSL': [2930], 'More': [2936], 'striking': [2937], 'Sia-recognizing': [2942, 2994], 'lectins,': [2943, 2995], 'degree': [2955], 'enhanced': [2959, 3025, 3077, 3205, 3275, 3361, 3548, 3559, 3641, 3688, 3707, 3874, 3914, 3946], 'this,': [2965], 'performed': [2967, 3567, 4035], 'β1,4Gal-recognizing': [2971], 'RCA120,': [2972], 'since': [2973, 3902, 4007], 'capping': [2976], 'β1,4Gal': [2978], 'sialic': [2980, 3161, 3415], 'blocks': [2982], 'RCA120.': [2986], 'Consistent': [2987], 'substantial': [2999], 'reduction': [3000, 3015], 'RCA120': [3002], '2B,': [3008, 3017], 'left).': [3009], 'neuraminidase': [3011, 3048], 'right),': [3018, 3386], '(compare': [3050], 'second': [3052], 'seventh': [3054], 'lanes,': [3055], 'third': [3057], 'eighth': [3059], 'lanes': [3060], 'Fig.': [3062], '2C),': [3063], 'indicating': [3064], 'decreased': [3067, 4316], 'sialylation.': [3078, 3406], 'potentiated': [3085], 'visualized': [3090], 'means': [3098], 'click': [3101, 3178], 'chemistry': [3102, 3179], 'approach': [3103], '(36Laughlin': [3104], 'S.T.': [3105], 'Agard': [3106], 'N.J.': [3107], 'Baskin': [3108], 'Carrico': [3110], 'I.S.': [3111], 'Chang': [3112], 'P.V.': [3113], 'Ganguli': [3114], 'A.S.': [3115], 'Hangauer': [3116], 'Lo': [3118], 'Prescher': [3120], 'J.A.': [3121], 'Bertozzi': [3122], 'C.R.': [3123], 'Metabolic': [3124], 'labeling': [3125], 'azido': [3129], 'sugars': [3130], 'visualization': [3132], 'glycoproteomics.Methods': [3134], 'Enzymol.': [3135], '415:': [3137], '230-250Crossref': [3138], '(100)': [3141], 'Control': [3144], 'incubated': [3149, 3585], 'equivalent': [3151], 'amounts': [3152, 3378, 3520, 3649], 'N-azidoacetylmannosamine': [3154], '(ManNAz),': [3155], 'converted': [3158], 'CMP-N-azidoacetyl': [3160], '(SiaNAz)': [3163], 'transferred': [3165], 'glycoconjugates': [3167], 'sialyltransferases': [3169, 3841], 'detection': [3173], 'SiaNAz-labeled': [3175], 'labeled': [3185], 'had': [3190], 'dramatically': [3191], 'comparison': [3194], '2D),': [3199], 'culture': [3215], 'media': [3216], 'displayed': [3221], 'MAM': [3226, 3242, 3574, 3611], '2E),': [3229], 'excluding': [3230, 3683], 'possibility': [3232, 3685, 3871], 'secretion': [3249], 'sialylated': [3251], 'proteins.': [3252, 4021], 'These': [3253, 3539, 4091], 'collective': [3254], 'data': [3255, 4092], 'demonstrate': [3256], 'apparatus.': [3267], 'obtain': [3269], 'convincing': [3271], 'evidence': [3272], 'next': [3281, 3892, 4109], 'MS.': [3286], 'released': [3289], 'reduced,': [3302], 'alditols': [3306], 'then': [3308], 'LC-ESI-MS': [3311], '3A,': [3313], 'Figs.': [3314], 'S1': [3315], 'S2).': [3317], 'detected': [3319], '202': [3320], '(Table': [3322], 'S1)': [3323], 'di-,': [3331], 'tri-,': [3332], 'tetra-sialylated': [3334], 'decreases': [3337], 'mono-': [3342], 'nonsialylated': [3344], '3B,': [3354, 3385], 'left),': [3355, 3481], 'clearly': [3356, 3741], 'above': [3368], 'results.': [3369], 'contrast,': [3371], 'no': [3372], 'remarkable': [3373], 'differences': [3374], 'relative': [3377], 'fucosylated': [3380], 'effects': [3390], 'global': [3399], 'but,': [3400], 'rather,': [3401], 'somewhat': [3403], 'selective': [3404], 'carried': [3409], 'out': [3410], 'linkage-specific': [3412, 3713], 'analysis': [3413], 'acids': [3416], 'biantennary': [3420], 'Based': [3422], 'chromatograms': [3425], 'fetuin': [3431], 'sample': [3432], 'whose': [3433], 'Sia': [3434, 3489, 3509], 'linkages': [3435, 3490, 3510], 'already': [3437], 'determined': [3439], '(37Nakano': [3440], 'Saldanha': [3442], 'Göbel': [3444], 'Kavallaris': [3446], 'Packer': [3448], 'N.H.': [3449], 'alterations': [3454], 'desoxyepothilone': [3460], 'resistant': [3462], 'leukemia': [3463], 'cells.Mol.': [3464], 'Proteomics.': [3466], '10:': [3468], '1-12Abstract': [3469], '(72)': [3476], 'S1,': [3480], 'able': [3484], 'assign': [3487], 'isomer,': [3494], 'even': [3495], 'though': [3496], 'extracted': [3498], 'ion': [3499], 'chromatogram': [3500], '(EIC)': [3501], 'included': [3502], 'S1).': [3512], 'As': [3513, 3974], 'result,': [3515], 'α2,3-': [3522, 3636], 'α2,6-sialylated': [3525], 'elevated': [3529], '3C,': [3535], 'indicated': [3536], 'pink).': [3538], 'show': [3541, 4093], 'especially': [3547], 'ensure': [3553], 'MS': [3555], 'pull-down': [3568], 'assays': [3569], 'SSA': [3571, 3626], '(α2,6Sia)': [3572], '(α2,3Sia)': [3575], 'lectins.': [3576], 'Lysates': [3577], 'SSA-': [3587], 'MAM-agarose,': [3589], 'bound': [3592], 'drastically': [3613], '4A,': [3620, 3631], 'right': [3621], 'panel),': [3622, 3633], 'barely': [3628], 'changed': [3629], 'middle': [3632], 'α2,6-sialylation': [3639], 'measured': [3647, 3831], 'CMP-N-acetylneuraminic': [3651], '(NeuAc),': [3653], 'substrate': [3656], 'CMP-NeuAc': [3667], 'decreased,': [3669], 'being': [3672], '4B),': [3682], 'increase': [3697], 'substrate.': [3701], 'Combined': [3702], 'fact': [3705], 'global,': [3716], 'reasoned': [3718], 'depletion': [3734], 'Rab11.': [3736], 'recent': [3738], 'among': [3744], 'α2,3-siayltransferases,': [3746], 'dominant': [3750], 'enzyme': [3751], '(38Qi': [3763], 'Isaji': [3765], 'Duan': [3767], 'Yang': [3769], 'ST3GAL3,': [3777], 'ST3GAL6': [3780], 'differ': [3781], 'specificities': [3790], 'target': [3795, 4020, 4049], 'proteins.FASEB': [3796], '34:': [3799], '881-897Crossref': [3800], '(20)': [3803], 'prompted': [3807], 'us': [3808, 4061], 'hypothesize': [3810], 'address': [3824], 'issue,': [3826], 'real-time': [3828], 'PCR,': [3829], 'mRNA': [3836, 3855, 4096], 'well': [3838], '4C).': [3867], 'excludes': [3869], 'upregulation': [3883], 'gene.': [3890], 'half-life': [3897], 'aberrantly': [3904], 'high': [3905], 'stability': [3906, 3997], 'might': [3911, 4013], 'α2,3-sialylation.': [3915], 'endogenous': [3918], 'difficult': [3922], 'detect': [3924], 'low': [3928], 'overexpressed': [3932], 'myc-tagged': [3933], 'first': [3942], 'confirmed': [3943], 'ST3GAL4-myc-expressing': [3951], 'S3).': [3955], 'steady-state': [3957], 'expressed': [3961, 3981, 4076], 'comparable': [3965], '4D).': [3973], 'exogenously': [3980], 'similar': [3987, 4083], 'suggests': [3994], 'unlikely': [4004], 'altered.': [4005], 'trafficking,': [4011], 'degradation': [4017, 4025, 4065, 4072], 'affected': [4030, 4104], 'knockdown,': [4033], 'cycloheximide': [4036], '(CHX)': [4037], 'chase': [4038], 'experiments.': [4039], 'CHX': [4040, 4055], 'inhibitor,': [4045], 'chasing': [4047], 'presence': [4053], 'time': [4059], 'enables': [4060], 'estimate': [4063], 'speed.': [4066], 'rates': [4073], '4E).': [4090], 'ST3GAL4.': [4115], 'shown': [4119], 'TGN': [4128], '(39De': [4132], 'Graaf': [4133], 'Zwart': [4135], 'W.T.': [4136], 'Van': [4137, 4152, 4156], 'Dijken': [4138], 'R.A.J.': [4139], 'Deneka': [4140], 'Schulz': [4142], 'T.K.F.': [4143], 'Geijsen': [4144], 'Coffer': [4146], 'Gadella': [4148], 'Verkleij': [4150], 'A.J.': [4151], 'Der': [4153], 'Sluijs': [4154], 'Bergen': [4157], 'En': [4158], 'Henegouwen': [4159], 'P.M.P.': [4160], 'Phosphatidylinositol': [4161], '4-kinaseβ': [4162], 'critical': [4164], 'rab11': [4169], 'complex.Mol.': [4173], '2038-2047Crossref': [4178], '(114)': [4181], '40Parmar': [4184], 'H.B.': [4185], 'Barr': [4188], 'F.A.': [4189], 'tribasic': [4192], 'directs': [4196], 'cargo': [4197], 'interaction': [4199], 'AP-1': [4204], '–': [4205, 4208], 'dependent': [4206], 'trafficking.Mol.': [4211], '1320-1331Crossref': [4216], '(16)': [4218], 'hypothesized': [4222], 'Rab11-mediated': [4225], 'could': [4230], 'Immunofluorescence': [4236], 'staining': [4237], 'although': [4240], 'mainly': [4243], 'colocalized': [4244], 'TGN46': [4246], '(a': [4247], 'trans': [4251], 'network': [4253], '(TGN))': [4254], '5A),': [4256], 'non-Golgi': [4262, 4310], 'vesicles': [4263], '5B,': [4265], 'arrowheads).': [4266], 'Costaining': [4267], 'markers': [4271], 'Transferrin': [4276], 'receptor': [4277], '(TfR)': [4278], '(recycling': [4279], 'endosomes),': [4280, 4283], 'EEA1': [4281], '(early': [4282], 'LAMP2': [4285], '(late': [4286], 'lysosomes),': [4289], 'partially': [4294], 'PGCs': [4297], '5C).': [4304], 'number': [4307], 'ST3GAL4-positive': [4309], 'dots': [4311], '5A)': [4313], '5D),': [4325], 'while': [4326], '5E),': [4341]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3127744119', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-12-30T10:36:53.769414', 'created_date': '2021-02-15'}
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