Publication Information

{'id': 'https://openalex.org/W3123828447', 'doi': 'https://doi.org/10.3389/fnmol.2020.608001', 'title': 'NPY and Gene Therapy for Epilepsy: How, When,... and Y', 'display_name': 'NPY and Gene Therapy for Epilepsy: How, When,... and Y', 'publication_year': 2021, 'publication_date': '2021-01-22', 'ids': {'openalex': 'https://openalex.org/W3123828447', 'doi': 'https://doi.org/10.3389/fnmol.2020.608001', 'mag': '3123828447', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33551745', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7862707'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fnmol.2020.608001', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fnmol.2020.608001/pdf', 'source': {'id': 'https://openalex.org/S39538987', 'display_name': 'Frontiers in Molecular Neuroscience', 'issn_l': '1662-5099', 'issn': ['1662-5099'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fnmol.2020.608001/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5034624092', 'display_name': 'Stefano Cattaneo', 'orcid': 'https://orcid.org/0000-0002-4287-692X'}, 'institutions': [{'id': 'https://openalex.org/I154387261', 'display_name': 'Vita-Salute San Raffaele University', 'ror': 'https://ror.org/01gmqr298', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I154387261']}, {'id': 'https://openalex.org/I292310028', 'display_name': 'San Raffaele University of Rome', 'ror': 'https://ror.org/02rwycx38', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I292310028']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Stefano Cattaneo', 'raw_affiliation_strings': ['San Raffaele Scientific Institute, Milan, Italy', 'Vita-Salute San Raffaele University, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Vita-Salute San Raffaele University, Milan, Italy', 'institution_ids': ['https://openalex.org/I154387261']}, {'raw_affiliation_string': 'San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I292310028']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039534612', 'display_name': 'Gianluca Verlengia', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I292310028', 'display_name': 'San Raffaele University of Rome', 'ror': 'https://ror.org/02rwycx38', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I292310028']}, {'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Gianluca Verlengia', 'raw_affiliation_strings': ['Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy', 'San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I292310028']}, {'raw_affiliation_string': 'Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010682710', 'display_name': 'Pietro Marino', 'orcid': 'https://orcid.org/0000-0002-3465-3814'}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Pietro Marino', 'raw_affiliation_strings': ['Department of Medical Sciences, Section of Pediatrics, University of Ferrara, Ferrara, Italy', 'Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Sciences, Section of Pediatrics, University of Ferrara, Ferrara, Italy', 'institution_ids': ['https://openalex.org/I201324441']}, {'raw_affiliation_string': 'Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039256755', 'display_name': 'Michele Simonato', 'orcid': 'https://orcid.org/0000-0002-3586-2693'}, 'institutions': [{'id': 'https://openalex.org/I154387261', 'display_name': 'Vita-Salute San Raffaele University', 'ror': 'https://ror.org/01gmqr298', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I154387261']}, {'id': 'https://openalex.org/I292310028', 'display_name': 'San Raffaele University of Rome', 'ror': 'https://ror.org/02rwycx38', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I292310028']}, {'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Michele Simonato', 'raw_affiliation_strings': ['Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy', 'San Raffaele Scientific Institute, Milan, Italy', 'Vita-Salute San Raffaele University, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Vita-Salute San Raffaele University, Milan, Italy', 'institution_ids': ['https://openalex.org/I154387261']}, {'raw_affiliation_string': 'San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I292310028']}, {'raw_affiliation_string': 'Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5000207843', 'display_name': 'Barbara Bettegazzi', 'orcid': 'https://orcid.org/0000-0001-5842-105X'}, 'institutions': [{'id': 'https://openalex.org/I154387261', 'display_name': 'Vita-Salute San Raffaele University', 'ror': 'https://ror.org/01gmqr298', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I154387261']}, {'id': 'https://openalex.org/I292310028', 'display_name': 'San Raffaele University of Rome', 'ror': 'https://ror.org/02rwycx38', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I292310028']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Barbara Bettegazzi', 'raw_affiliation_strings': ['San Raffaele Scientific Institute, Milan, Italy', 'Vita-Salute San Raffaele University, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Vita-Salute San Raffaele University, Milan, Italy', 'institution_ids': ['https://openalex.org/I154387261']}, {'raw_affiliation_string': 'San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I292310028']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5000207843'], 'corresponding_institution_ids': ['https://openalex.org/I154387261', 'https://openalex.org/I292310028'], 'apc_list': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'apc_paid': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'fwci': 1.645, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 39, 'citation_normalized_percentile': {'value': 0.998054, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '13', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9769, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10725', 'display_name': 'RNA Interference and Gene Delivery', 'score': 0.9753, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C93984277', 'wikidata': 'https://www.wikidata.org/wiki/Q24782073', 'display_name': 'Neuropeptide Y receptor', 'level': 4, 'score': 0.7889323}, {'id': 'https://openalex.org/C2778186239', 'wikidata': 'https://www.wikidata.org/wiki/Q41571', 'display_name': 'Epilepsy', 'level': 2, 'score': 0.7719679}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.71965843}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5498148}, {'id': 'https://openalex.org/C2779343474', 'wikidata': 'https://www.wikidata.org/wiki/Q3109175', 'display_name': 'Context (archaeology)', 'level': 2, 'score': 0.5117993}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.41107786}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.3993687}, {'id': 'https://openalex.org/C118303440', 'wikidata': 'https://www.wikidata.org/wiki/Q419968', 'display_name': 'Neuropeptide', 'level': 3, 'score': 0.2561153}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.12136024}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 7, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fnmol.2020.608001', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fnmol.2020.608001/pdf', 'source': {'id': 'https://openalex.org/S39538987', 'display_name': 'Frontiers in Molecular Neuroscience', 'issn_l': '1662-5099', 'issn': ['1662-5099'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/09e2b9dd9f6145ab94d7c3626cfafbbe', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc7862707', 'pdf_url': 'https://europepmc.org/articles/pmc7862707?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.frontiersin.org/articles/10.3389/fnmol.2020.608001/full', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fnmol.2020.608001/pdf?isPublishedV2=False', 'source': {'id': 'https://openalex.org/S4306400369', 'display_name': 'Institutional Research Information System University of Ferrara (University of Ferrara)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I201324441', 'host_organization_name': 'University of Ferrara', 'host_organization_lineage': ['https://openalex.org/I201324441'], 'host_organization_lineage_names': ['University of Ferrara'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/11392/2433606', 'pdf_url': 'https://iris.unife.it/bitstream/11392/2433606/2/fnmol-13-608001.pdf', 'source': {'id': 'https://openalex.org/S4306400369', 'display_name': 'Institutional Research Information System University of Ferrara (University of Ferrara)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I201324441', 'host_organization_name': 'University of Ferrara', 'host_organization_lineage': ['https://openalex.org/I201324441'], 'host_organization_lineage_names': ['University of Ferrara'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862707', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33551745', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fnmol.2020.608001', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fnmol.2020.608001/pdf', 'source': {'id': 'https://openalex.org/S39538987', 'display_name': 'Frontiers in Molecular Neuroscience', 'issn_l': '1662-5099', 'issn': ['1662-5099'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 153, 'referenced_works': ['https://openalex.org/W1487194851', 'https://openalex.org/W1520380966', 'https://openalex.org/W1528241356', 'https://openalex.org/W1530842932', 'https://openalex.org/W1541355642', 'https://openalex.org/W1606297570', 'https://openalex.org/W1624828016', 'https://openalex.org/W1672499007', 'https://openalex.org/W1744561736', 'https://openalex.org/W1903951249', 'https://openalex.org/W1921965655', 'https://openalex.org/W1933062462', 'https://openalex.org/W1936892273', 'https://openalex.org/W1937309249', 'https://openalex.org/W1938281796', 'https://openalex.org/W1942144965', 'https://openalex.org/W1958511432', 'https://openalex.org/W1966242968', 'https://openalex.org/W1966640589', 'https://openalex.org/W1967817569', 'https://openalex.org/W1968753905', 'https://openalex.org/W1969881895', 'https://openalex.org/W1969990009', 'https://openalex.org/W1970321055', 'https://openalex.org/W1972605153', 'https://openalex.org/W1980200864', 'https://openalex.org/W1981364522', 'https://openalex.org/W1982399527', 'https://openalex.org/W1986324555', 'https://openalex.org/W1987306390', 'https://openalex.org/W1988628530', 'https://openalex.org/W1993782990', 'https://openalex.org/W1995087873', 'https://openalex.org/W1996645236', 'https://openalex.org/W1996942493', 'https://openalex.org/W2001034344', 'https://openalex.org/W2002889079', 'https://openalex.org/W2006216839', 'https://openalex.org/W2008009531', 'https://openalex.org/W2008682721', 'https://openalex.org/W2009443158', 'https://openalex.org/W2009824033', 'https://openalex.org/W2009950176', 'https://openalex.org/W2010578728', 'https://openalex.org/W2011052987', 'https://openalex.org/W2012396017', 'https://openalex.org/W2013184139', 'https://openalex.org/W2013523224', 'https://openalex.org/W2014138879', 'https://openalex.org/W2014505983', 'https://openalex.org/W2014814466', 'https://openalex.org/W2017763577', 'https://openalex.org/W2021258327', 'https://openalex.org/W2021771893', 'https://openalex.org/W2021931052', 'https://openalex.org/W2025502308', 'https://openalex.org/W2026982802', 'https://openalex.org/W2029651085', 'https://openalex.org/W2033253852', 'https://openalex.org/W2034916864', 'https://openalex.org/W2036264239', 'https://openalex.org/W2040570622', 'https://openalex.org/W2040626092', 'https://openalex.org/W2044141202', 'https://openalex.org/W2044431563', 'https://openalex.org/W2045377887', 'https://openalex.org/W2045413817', 'https://openalex.org/W2045890604', 'https://openalex.org/W2048610961', 'https://openalex.org/W2049096060', 'https://openalex.org/W2049266316', 'https://openalex.org/W2049473220', 'https://openalex.org/W2050098144', 'https://openalex.org/W2050452127', 'https://openalex.org/W2051829755', 'https://openalex.org/W2052052752', 'https://openalex.org/W2053058176', 'https://openalex.org/W2054337977', 'https://openalex.org/W2055952563', 'https://openalex.org/W2057306553', 'https://openalex.org/W2063608942', 'https://openalex.org/W2068227743', 'https://openalex.org/W2068774971', 'https://openalex.org/W2072159468', 'https://openalex.org/W2073683673', 'https://openalex.org/W2075143387', 'https://openalex.org/W2075390326', 'https://openalex.org/W2077518606', 'https://openalex.org/W2077766248', 'https://openalex.org/W2077825677', 'https://openalex.org/W2078948823', 'https://openalex.org/W2079201209', 'https://openalex.org/W2079795703', 'https://openalex.org/W2079803201', 'https://openalex.org/W2082262682', 'https://openalex.org/W2082394182', 'https://openalex.org/W2083353215', 'https://openalex.org/W2084604177', 'https://openalex.org/W2084975523', 'https://openalex.org/W2085108790', 'https://openalex.org/W2085371153', 'https://openalex.org/W2085655953', 'https://openalex.org/W2085792819', 'https://openalex.org/W2087111008', 'https://openalex.org/W2090386023', 'https://openalex.org/W2094141131', 'https://openalex.org/W2094242137', 'https://openalex.org/W2096870121', 'https://openalex.org/W2098092258', 'https://openalex.org/W2100790556', 'https://openalex.org/W2107477632', 'https://openalex.org/W2109379016', 'https://openalex.org/W2110325111', 'https://openalex.org/W2112282765', 'https://openalex.org/W2119968602', 'https://openalex.org/W2120870776', 'https://openalex.org/W2125381530', 'https://openalex.org/W2126102278', 'https://openalex.org/W2127170155', 'https://openalex.org/W2131614422', 'https://openalex.org/W2133445440', 'https://openalex.org/W2135552976', 'https://openalex.org/W2137545323', 'https://openalex.org/W2139928989', 'https://openalex.org/W2140767046', 'https://openalex.org/W2151679423', 'https://openalex.org/W2156566914', 'https://openalex.org/W2158790858', 'https://openalex.org/W2184875208', 'https://openalex.org/W2199739252', 'https://openalex.org/W2253014309', 'https://openalex.org/W2341751247', 'https://openalex.org/W2409926284', 'https://openalex.org/W2470134062', 'https://openalex.org/W2543569114', 'https://openalex.org/W2552151356', 'https://openalex.org/W2611091164', 'https://openalex.org/W2792318883', 'https://openalex.org/W2794530037', 'https://openalex.org/W2802089023', 'https://openalex.org/W2848432531', 'https://openalex.org/W2885968272', 'https://openalex.org/W2898329333', 'https://openalex.org/W2902714952', 'https://openalex.org/W2914823219', 'https://openalex.org/W2955720713', 'https://openalex.org/W2973304723', 'https://openalex.org/W2973361192', 'https://openalex.org/W2996699425', 'https://openalex.org/W3013130019', 'https://openalex.org/W3045165633', 'https://openalex.org/W3143202161', 'https://openalex.org/W4250887695'], 'related_works': ['https://openalex.org/W4228999517', 'https://openalex.org/W2462414993', 'https://openalex.org/W2460679215', 'https://openalex.org/W2374764865', 'https://openalex.org/W2367619245', 'https://openalex.org/W2152916740', 'https://openalex.org/W2092743131', 'https://openalex.org/W2040994074', 'https://openalex.org/W2034986159', 'https://openalex.org/W1974652345'], 'abstract_inverted_index': {'Neuropeptide': [0], 'Y': [1], '(NPY)': [2], 'is': [3, 17, 85, 166], 'a': [4, 18, 41, 62, 129, 163, 188], 'neuropeptide': [5], 'abundantly': [6], 'expressed': [7], 'in': [8, 73, 106, 118], 'the': [9, 34, 80, 107, 110, 133, 145, 150, 156, 200], 'mammalian': [10], 'central': [11, 35], 'and': [12, 26, 30, 76, 99, 141], 'peripheral': [13], 'nervous': [14, 36], 'system.': [15], 'NPY': [16, 38, 60, 84, 154, 160, 180], 'pleiotropic': [19], 'molecule,': [20], 'which': [21], 'influences': [22], 'cell': [23], 'proliferation,': [24], 'cardiovascular': [25], 'metabolic': [27], 'function,': [28], 'pain': [29, 58], 'neuronal': [31], 'excitability.': [32], 'In': [33, 79, 102], 'system,': [37], 'acts': [39], 'as': [40, 89, 162], 'neuromodulator,': [42], 'affecting': [43], 'pathways': [44, 72], 'that': [45, 93, 194], 'range': [46], 'from': [47], 'cellular': [48, 77], '(excitability,': [49], 'neurogenesis)': [50], 'to': [51, 87, 179, 198], 'circuit': [52], 'level': [53], '(food': [54], 'intake,': [55], 'stress': [56], 'response,': [57], 'perception).': [59], 'has': [61], 'broad': [63], 'repertoire': [64], 'of': [65, 82, 112, 121, 135, 144, 153, 158, 169, 191], 'receptor': [66], 'subtypes,': [67], 'each': [68], 'activating': [69], 'specific': [70], 'signaling': [71], 'different': [74], 'tissues': [75], 'sub-regions.': [78], 'context': [81], 'epilepsy,': [83], 'thought': [86], 'act': [88], 'an': [90], 'endogenous': [91], 'anticonvulsant': [92], 'performs': [94], 'its': [95, 104, 184], 'action': [96], 'through': [97], 'Y2': [98], 'Y5': [100], 'receptors.': [101], 'fact,': [103], 'overexpression': [105], 'brain': [108], 'with': [109, 187], 'aid': [111], 'viral': [113], 'vectors': [114], 'can': [115], 'suppress': [116], 'seizures': [117], 'animal': [119], 'models': [120], 'epilepsy.': [122, 208], 'Therefore,': [123], 'NPY-based': [124, 203], 'gene': [125, 204], 'therapy': [126, 205], 'may': [127], 'represent': [128], 'novel': [130], 'approach': [131], 'for': [132, 139, 207], 'treatment': [134], 'epilepsy': [136], 'patients,': [137], 'particularly': [138], 'pharmaco-resistant': [140], 'genetic': [142], 'forms': [143], 'disease.': [146], 'Nonetheless,': [147], 'considering': [148], 'all': [149], 'aforementioned': [151], 'aspects': [152], 'signaling,': [155], 'study': [157], 'possible': [159], 'applications': [161], 'therapeutic': [164], 'molecule': [165], 'not': [167], 'devoid': [168], 'critical': [170, 189], 'aspects.': [171], 'The': [172], 'present': [173], 'review': [174], 'will': [175], 'summarize': [176], 'data': [177], 'related': [178], 'biology,': [181], 'focusing': [182], 'on': [183], 'anti-epileptic': [185], 'effects,': [186], 'appraisal': [190], 'key': [192], 'elements': [193], 'could': [195], 'be': [196], 'exploited': [197], 'improve': [199], 'already': [201], 'existing': [202], 'approaches': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3123828447', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 15}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 6}], 'updated_date': '2025-01-06T16:58:01.886294', 'created_date': '2021-02-01'}