Title: Side effects of lopinavir/ritonavir for COVID-19
Abstract: AIM: To study the regularity and characteristics of side effects of lopinavir/ritonavir for COVID-19 METHODS: The type of side effects, general information, medical history and prognosis in 61 confirmed and suspected COVID-19 patients with lopinavir/ritonavir were analyzed RESULTS: Among the 61 patients, 41(67 21%) had lopinavir/ritonavir related side effects, mainly manifested as gastrointestinal reactions (82 93%) and liver function damage (53 66%) Old age, long course of disease and chronic gastrointestinal disease are independent risk factors for side effects CONCLUSION: Lopinavir/ritonavir has a high incidence of side effects and can be used in COVID-19 patients under the condition of close observation of the patient's symptoms and test results Special population should improve pharmaceutical care to ensure the safety of drug use
Publication Year: 2020
Publication Date: 2020-01-01
Language: en
Type: article
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