Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3121405476', 'doi': 'https://doi.org/10.1101/2020.06.30.180018', 'title': 'Progression of the late-stage divisome is unaffected by the depletion of the cytoplasmic FtsZ pool', 'display_name': 'Progression of the late-stage divisome is unaffected by the depletion of the cytoplasmic FtsZ pool', 'publication_year': 2020, 'publication_date': '2020-07-01', 'ids': {'openalex': 'https://openalex.org/W3121405476', 'doi': 'https://doi.org/10.1101/2020.06.30.180018', 'mag': '3121405476'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2020.06.30.180018', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2021/01/19/2020.06.30.180018.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'type': 'preprint', 'type_crossref': 'posted-content', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.biorxiv.org/content/biorxiv/early/2021/01/19/2020.06.30.180018.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5042092220', 'display_name': 'Nadine Silber', 'orcid': 'https://orcid.org/0000-0002-4512-589X'}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Nadine Silber', 'raw_affiliation_strings': ['Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}, {'raw_affiliation_string': 'Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011992197', 'display_name': 'Christian T. Mayer', 'orcid': 'https://orcid.org/0000-0002-0256-9650'}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Christian Mayer', 'raw_affiliation_strings': ['Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}, {'raw_affiliation_string': 'Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085323598', 'display_name': 'Cruz L Matos de Opitz', 'orcid': 'https://orcid.org/0000-0002-0098-2783'}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Cruz L Matos de Opitz', 'raw_affiliation_strings': ['Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}, {'raw_affiliation_string': 'Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010824958', 'display_name': 'Peter Saß', 'orcid': 'https://orcid.org/0000-0002-4477-2382'}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'Peter Sass', 'raw_affiliation_strings': ['Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}, {'raw_affiliation_string': 'Cluster of Excellence - Controlling Microbes to Fight Infections, University of Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5010824958'], 'corresponding_institution_ids': ['https://openalex.org/I8087733'], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 6, 'citation_normalized_percentile': {'value': 0.749731, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10593', 'display_name': 'Bacterial biofilms and quorum sensing', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ftsz', 'display_name': 'FtsZ', 'score': 0.9988639}, {'id': 'https://openalex.org/keywords/treadmilling', 'display_name': 'Treadmilling', 'score': 0.70146906}, {'id': 'https://openalex.org/keywords/division-ring', 'display_name': 'Division ring', 'score': 0.4206068}], 'concepts': [{'id': 'https://openalex.org/C2776237524', 'wikidata': 'https://www.wikidata.org/wiki/Q24773445', 'display_name': 'FtsZ', 'level': 4, 'score': 0.9988639}, {'id': 'https://openalex.org/C85813293', 'wikidata': 'https://www.wikidata.org/wiki/Q188909', 'display_name': 'Cell division', 'level': 3, 'score': 0.818485}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.74926853}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.702019}, {'id': 'https://openalex.org/C205309164', 'wikidata': 'https://www.wikidata.org/wiki/Q201389', 'display_name': 'Treadmilling', 'level': 5, 'score': 0.70146906}, {'id': 'https://openalex.org/C45472230', 'wikidata': 'https://www.wikidata.org/wiki/Q1447198', 'display_name': 'Cytokinesis', 'level': 4, 'score': 0.66171837}, {'id': 'https://openalex.org/C2776634448', 'wikidata': 'https://www.wikidata.org/wiki/Q206920', 'display_name': 'Peptidoglycan', 'level': 3, 'score': 0.62157816}, {'id': 'https://openalex.org/C2777272437', 'wikidata': 'https://www.wikidata.org/wiki/Q131238', 'display_name': 'Bacillus subtilis', 'level': 3, 'score': 0.6039635}, {'id': 'https://openalex.org/C142669718', 'wikidata': 'https://www.wikidata.org/wiki/Q154626', 'display_name': 'Cytoskeleton', 'level': 3, 'score': 0.57440245}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5448078}, {'id': 'https://openalex.org/C31671303', 'wikidata': 'https://www.wikidata.org/wiki/Q650741', 'display_name': 'Division ring', 'level': 3, 'score': 0.4206068}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.3499405}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.24745414}, {'id': 'https://openalex.org/C60798267', 'wikidata': 'https://www.wikidata.org/wiki/Q1226939', 'display_name': 'Division (mathematics)', 'level': 2, 'score': 0.22100931}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.16667762}, {'id': 'https://openalex.org/C189040839', 'wikidata': 'https://www.wikidata.org/wiki/Q329638', 'display_name': 'Microfilament', 'level': 4, 'score': 0.1561901}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.12292859}, {'id': 'https://openalex.org/C94375191', 'wikidata': 'https://www.wikidata.org/wiki/Q11205', 'display_name': 'Arithmetic', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2020.06.30.180018', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2021/01/19/2020.06.30.180018.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/s42003-021-01789-9', 'pdf_url': 'https://www.nature.com/articles/s42003-021-01789-9.pdf', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2020.06.30.180018', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2021/01/19/2020.06.30.180018.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1651953691', 'https://openalex.org/W1992102420', 'https://openalex.org/W1998601289', 'https://openalex.org/W2019226454', 'https://openalex.org/W2036158497', 'https://openalex.org/W2076272826', 'https://openalex.org/W2090051748', 'https://openalex.org/W2108596213', 'https://openalex.org/W2110191238', 'https://openalex.org/W2114546212', 'https://openalex.org/W2142050501', 'https://openalex.org/W2144497462', 'https://openalex.org/W2152375302', 'https://openalex.org/W2154191173', 'https://openalex.org/W2163562422', 'https://openalex.org/W2266194320', 'https://openalex.org/W2551929191', 'https://openalex.org/W2588204280', 'https://openalex.org/W2588858142', 'https://openalex.org/W2594619756', 'https://openalex.org/W2740281799', 'https://openalex.org/W2790556376', 'https://openalex.org/W2951525168', 'https://openalex.org/W3002464534', 'https://openalex.org/W3045443897', 'https://openalex.org/W3108719152', 'https://openalex.org/W3121405476'], 'related_works': ['https://openalex.org/W4387006745', 'https://openalex.org/W3005271159', 'https://openalex.org/W2995215278', 'https://openalex.org/W2609716862', 'https://openalex.org/W2588858142', 'https://openalex.org/W2588204280', 'https://openalex.org/W2565752920', 'https://openalex.org/W2555403270', 'https://openalex.org/W2024435948', 'https://openalex.org/W2018696676'], 'abstract_inverted_index': {'Abstract': [0], 'Cell': [1], 'division': [2, 50, 151, 156], 'is': [3, 65], 'a': [4, 26, 57, 147], 'central': [5], 'and': [6, 12, 18, 123, 130, 168, 182], 'essential': [7, 116], 'process': [8], 'in': [9, 32, 95, 110], 'most': [10], 'bacteria,': [11], 'also': [13], 'due': [14], 'to': [15, 56], 'its': [16], 'complexity': [17], 'highly': [19], 'coordinated': [20], 'nature,': [21], 'it': [22], 'has': [23], 'emerged': [24], 'as': [25], 'promising': [27], 'new': [28], 'antibiotic': [29], 'target': [30], 'pathway': [31], 'recent': [33], 'years.': [34], 'We': [35], 'have': [36], 'previously': [37], 'shown': [38], 'that': [39, 64, 160], 'ADEP': [40, 78, 86, 108], 'antibiotics': [41], 'preferably': [42], 'induce': [43], 'the': [44, 47, 60, 74, 83, 88, 92, 101, 119, 133, 142, 155, 161, 164, 176], 'degradation': [45], 'of': [46, 59, 77, 85, 91, 103, 118, 132, 163, 179], 'major': [48], 'cell': [49, 150], 'protein': [51], 'FtsZ,': [52], 'thereby': [53], 'primarily': [54], 'leading': [55], 'depletion': [58], 'cytoplasmic': [61, 120, 165], 'FtsZ': [62, 69, 93, 105, 121, 125, 137, 166, 169], 'pool': [63, 122, 167], 'needed': [66], 'for': [67], 'treadmilling': [68], 'rings.': [70], 'To': [71], 'further': [72], 'investigate': [73], 'physiological': [75], 'consequences': [76], 'treatment,': [79], 'we': [80], 'here': [81], 'studied': [82], 'effect': [84], 'on': [87], 'different': [89], 'stages': [90, 178], 'ring': [94, 126, 170], 'rod-shaped': [96], 'bacteria.': [97], 'Our': [98], 'data': [99], 'reveal': [100], 'disintegration': [102], 'early': [104], 'rings': [106, 138], 'during': [107, 128, 175], 'treatment': [109], 'Bacillus': [111], 'subtilis': [112], ',': [113], 'indicating': [114], 'an': [115], 'role': [117], 'thus': [124, 158], 'dynamics': [127, 171], 'initiation': [129], 'maturation': [131], 'divisome.': [134], 'However,': [135], 'progressed': [136], 'finalized': [139], 'cytokinesis': [140], 'once': [141], 'septal': [143], 'peptidoglycan': [144], 'synthase': [145], 'PBP2b,': [146], 'late': [148, 177], 'stage': [149], 'protein,': [152], 'colocalized': [153], 'at': [154], 'site,': [157], 'implying': [159], 'concentration': [162], 'are': [172], 'less': [173], 'critical': [174], 'divisome': [180], 'assembly': [181], 'progression.': [183]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3121405476', 'counts_by_year': [{'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 3}], 'updated_date': '2024-12-31T00:02:40.659464', 'created_date': '2021-02-01'}