Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3111459776', 'doi': 'https://doi.org/10.3389/fvets.2020.00527', 'title': 'Licochalcone a Exhibits Leishmanicidal Activity in vitro and in Experimental Model of Leishmania (Leishmania) Infantum', 'display_name': 'Licochalcone a Exhibits Leishmanicidal Activity in vitro and in Experimental Model of Leishmania (Leishmania) Infantum', 'publication_year': 2020, 'publication_date': '2020-12-10', 'ids': {'openalex': 'https://openalex.org/W3111459776', 'doi': 'https://doi.org/10.3389/fvets.2020.00527', 'mag': '3111459776', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33363224', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7758436'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fvets.2020.00527', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fvets.2020.00527/pdf', 'source': {'id': 'https://openalex.org/S2594976040', 'display_name': 'Frontiers in Veterinary Science', 'issn_l': '2297-1769', 'issn': ['2297-1769'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fvets.2020.00527/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5034524666', 'display_name': 'Jeovane Henrique de Souza', 'orcid': 'https://orcid.org/0000-0002-0922-3214'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Julia M. Souza', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022740044', 'display_name': 'Érica A. A. de Carvalho', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Érica A. A. de Carvalho', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038363397', 'display_name': 'Ana Carolina Bolela Bovo Cândido', 'orcid': 'https://orcid.org/0000-0002-1431-5375'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Ana Carolina B. B. Candido', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031865881', 'display_name': 'Rafael Paranhos de Mendonça', 'orcid': 'https://orcid.org/0000-0002-7694-2817'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Rafael P. de Mendonça', 'raw_affiliation_strings': ['Pós Graduação em Ciência Animal, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Pós Graduação em Ciência Animal, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051648568', 'display_name': 'Maria Fernanda da Silva', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Maria Fernanda da Silva', 'raw_affiliation_strings': ['Pós Graduação em Ciência Animal, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Pós Graduação em Ciência Animal, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057038303', 'display_name': 'Renato L. T. Parreira', 'orcid': 'https://orcid.org/0000-0002-5623-9833'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Renato L. T. Parreira', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086150728', 'display_name': 'Fernanda Gosuen Gonçalves Dias', 'orcid': 'https://orcid.org/0000-0001-6072-4789'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Fernanda G. G. Dias', 'raw_affiliation_strings': ['Pós Graduação em Ciência Animal, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Pós Graduação em Ciência Animal, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010784964', 'display_name': 'Sérgio Ricardo Ambrósio', 'orcid': 'https://orcid.org/0000-0001-5032-3930'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Sérgio R. Ambrósio', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084740015', 'display_name': 'Andrea T. Arantes', 'orcid': None}, 'institutions': [], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Andrea T. Arantes', 'raw_affiliation_strings': ['Centro Tecnológico Agropecuário, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Centro Tecnológico Agropecuário, Brazil', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088131994', 'display_name': 'Ademar Alves da Silva Filho', 'orcid': 'https://orcid.org/0000-0002-9096-1336'}, 'institutions': [{'id': 'https://openalex.org/I101100930', 'display_name': 'Universidade Federal de Juiz de Fora', 'ror': 'https://ror.org/04yqw9c44', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I101100930']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Ademar A. da Silva Filho', 'raw_affiliation_strings': ['Departamento de Ciências Farmacêuticas, Universidade Federal de Juiz de Fora, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Ciências Farmacêuticas, Universidade Federal de Juiz de Fora, Brazil', 'institution_ids': ['https://openalex.org/I101100930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089826966', 'display_name': 'Aline N. Nascimento', 'orcid': 'https://orcid.org/0000-0002-5079-3120'}, 'institutions': [{'id': 'https://openalex.org/I71715416', 'display_name': 'Universidade Federal do ABC', 'ror': 'https://ror.org/028kg9j04', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I71715416']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Aline N. Nascimento', 'raw_affiliation_strings': ['Centro de Ciências Naturais e Humanas, Universidade Federal Do ABC, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Centro de Ciências Naturais e Humanas, Universidade Federal Do ABC, Brazil', 'institution_ids': ['https://openalex.org/I71715416']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013376699', 'display_name': 'Monique Rodrigues da Costa', 'orcid': 'https://orcid.org/0000-0002-7575-2464'}, 'institutions': [{'id': 'https://openalex.org/I71715416', 'display_name': 'Universidade Federal do ABC', 'ror': 'https://ror.org/028kg9j04', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I71715416']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Monique R. Costa', 'raw_affiliation_strings': ['Centro de Ciências Naturais e Humanas, Universidade Federal Do ABC, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Centro de Ciências Naturais e Humanas, Universidade Federal Do ABC, Brazil', 'institution_ids': ['https://openalex.org/I71715416']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049184770', 'display_name': 'Mirela Inês de Sairre', 'orcid': 'https://orcid.org/0000-0002-6931-4214'}, 'institutions': [{'id': 'https://openalex.org/I71715416', 'display_name': 'Universidade Federal do ABC', 'ror': 'https://ror.org/028kg9j04', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I71715416']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Mirela I. Sairre', 'raw_affiliation_strings': ['Centro de Ciências Naturais e Humanas, Universidade Federal Do ABC, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Centro de Ciências Naturais e Humanas, Universidade Federal Do ABC, Brazil', 'institution_ids': ['https://openalex.org/I71715416']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019211813', 'display_name': 'Rodrigo Cássio Sola Veneziani', 'orcid': 'https://orcid.org/0000-0001-7057-9706'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Rodrigo C. S. Veneziani', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072639236', 'display_name': 'Lizandra Guidi Magalhães', 'orcid': 'https://orcid.org/0000-0003-2959-6752'}, 'institutions': [{'id': 'https://openalex.org/I3017598443', 'display_name': 'Universidade de Franca', 'ror': 'https://ror.org/04zyja509', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I3017598443']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Lizandra G. Magalhães', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'Pós Graduação em Ciência Animal, Universidade de Franca, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Pós Graduação em Ciência Animal, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}, {'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Exatas e Tecnológica, Universidade de Franca, Brazil', 'institution_ids': ['https://openalex.org/I3017598443']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'apc_paid': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'fwci': 1.981, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 14, 'citation_normalized_percentile': {'value': 0.871422, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '7', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10823', 'display_name': 'Global Burden of Leishmaniasis Incidence and Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10823', 'display_name': 'Global Burden of Leishmaniasis Incidence and Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12817', 'display_name': 'Pharmacological Effects of Licorice Roots', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12477', 'display_name': 'Immunotoxin Therapy for Cancer Treatment', 'score': 0.9932, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/amastigote', 'display_name': 'Amastigote', 'score': 0.9670923}, {'id': 'https://openalex.org/keywords/ic50', 'display_name': 'IC50', 'score': 0.68881685}, {'id': 'https://openalex.org/keywords/leishmaniasis', 'display_name': 'Leishmaniasis', 'score': 0.488897}], 'concepts': [{'id': 'https://openalex.org/C2781257258', 'wikidata': 'https://www.wikidata.org/wiki/Q1950789', 'display_name': 'Leishmania infantum', 'level': 4, 'score': 0.98537016}, {'id': 'https://openalex.org/C98319499', 'wikidata': 'https://www.wikidata.org/wiki/Q455445', 'display_name': 'Amastigote', 'level': 4, 'score': 0.9670923}, {'id': 'https://openalex.org/C2781092759', 'wikidata': 'https://www.wikidata.org/wiki/Q524818', 'display_name': 'Leishmania', 'level': 3, 'score': 0.71261805}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.70168895}, {'id': 'https://openalex.org/C2777752497', 'wikidata': 'https://www.wikidata.org/wiki/Q286779', 'display_name': 'IC50', 'level': 3, 'score': 0.68881685}, {'id': 'https://openalex.org/C109316439', 'wikidata': 'https://www.wikidata.org/wiki/Q246181', 'display_name': 'Cytotoxicity', 'level': 3, 'score': 0.6417458}, {'id': 'https://openalex.org/C2776555147', 'wikidata': 'https://www.wikidata.org/wiki/Q331283', 'display_name': 'Leishmaniasis', 'level': 2, 'score': 0.5399992}, {'id': 'https://openalex.org/C2778689377', 'wikidata': 'https://www.wikidata.org/wiki/Q2046113', 'display_name': 'Visceral leishmaniasis', 'level': 3, 'score': 0.51190794}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.4689913}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.43994614}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42895532}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.37287354}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.27665508}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.268284}, {'id': 'https://openalex.org/C71928629', 'wikidata': 'https://www.wikidata.org/wiki/Q804206', 'display_name': 'Parasite hosting', 'level': 2, 'score': 0.09002668}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fvets.2020.00527', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fvets.2020.00527/pdf', 'source': {'id': 'https://openalex.org/S2594976040', 'display_name': 'Frontiers in Veterinary Science', 'issn_l': '2297-1769', 'issn': ['2297-1769'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/d81a61290d4c4c848f2b3eb4621d1d40', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758436', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33363224', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fvets.2020.00527', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fvets.2020.00527/pdf', 'source': {'id': 'https://openalex.org/S2594976040', 'display_name': 'Frontiers in Veterinary Science', 'issn_l': '2297-1769', 'issn': ['2297-1769'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2016/24456-1'}, {'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2013/11164-4'}, {'funder': 'https://openalex.org/F4320321091', 'funder_display_name': 'Coordenação de Aperfeiçoamento de Pessoal de Nível Superior', 'award_id': '88881.133783/2016-01'}, {'funder': 'https://openalex.org/F4320321091', 'funder_display_name': 'Coordenação de Aperfeiçoamento de Pessoal de Nível Superior', 'award_id': '88882.36577/2019-01'}, {'funder': 'https://openalex.org/F4320321091', 'funder_display_name': 'Coordenação de Aperfeiçoamento de Pessoal de Nível Superior', 'award_id': '001'}, {'funder': 'https://openalex.org/F4320322025', 'funder_display_name': 'Conselho Nacional de Desenvolvimento Científico e Tecnológico', 'award_id': '303946/2018-0'}], 'datasets': [], 'versions': [], 'referenced_works_count': 48, 'referenced_works': ['https://openalex.org/W1733625577', 'https://openalex.org/W1772992353', 'https://openalex.org/W1904731249', 'https://openalex.org/W1937464541', 'https://openalex.org/W1975961722', 'https://openalex.org/W1981526535', 'https://openalex.org/W1995127073', 'https://openalex.org/W1999498172', 'https://openalex.org/W1999927633', 'https://openalex.org/W2007306038', 'https://openalex.org/W2011716103', 'https://openalex.org/W2014815058', 'https://openalex.org/W2018794689', 'https://openalex.org/W2022298723', 'https://openalex.org/W2023912731', 'https://openalex.org/W2034595196', 'https://openalex.org/W2045728318', 'https://openalex.org/W2056131072', 'https://openalex.org/W2058732808', 'https://openalex.org/W2093071092', 'https://openalex.org/W2103323903', 'https://openalex.org/W2107781488', 'https://openalex.org/W2134531520', 'https://openalex.org/W2138539976', 'https://openalex.org/W2165602931', 'https://openalex.org/W2175917342', 'https://openalex.org/W2198907191', 'https://openalex.org/W2277440858', 'https://openalex.org/W2417921765', 'https://openalex.org/W2559798560', 'https://openalex.org/W2609425092', 'https://openalex.org/W2635199482', 'https://openalex.org/W2730840378', 'https://openalex.org/W2749939814', 'https://openalex.org/W2783841473', 'https://openalex.org/W2790312388', 'https://openalex.org/W2792279154', 'https://openalex.org/W2800853513', 'https://openalex.org/W2904775765', 'https://openalex.org/W2911111696', 'https://openalex.org/W2912348619', 'https://openalex.org/W2919646825', 'https://openalex.org/W2920836773', 'https://openalex.org/W2939367718', 'https://openalex.org/W2953279470', 'https://openalex.org/W4237570491', 'https://openalex.org/W4248850222', 'https://openalex.org/W4250179682'], 'related_works': ['https://openalex.org/W77589466', 'https://openalex.org/W4285798762', 'https://openalex.org/W324504601', 'https://openalex.org/W2924523848', 'https://openalex.org/W2427615828', 'https://openalex.org/W2283453949', 'https://openalex.org/W2171805457', 'https://openalex.org/W2126683399', 'https://openalex.org/W2113811423', 'https://openalex.org/W1139037058'], 'abstract_inverted_index': {'The': [0], 'efficacy': [1], 'of': [2, 27, 44, 59, 77, 91, 102, 123, 148, 175, 180, 234, 243], 'Licochalcone': [3], 'A': [4], '(LicoA)': [5], 'and': [6, 16, 23, 36, 61, 66, 99, 125, 130, 171, 188, 210, 214, 246], 'its': [7, 37], 'two': [8], 'analogs': [9, 38], 'were': [10, 39], 'reported': [11], 'against': [12, 41, 97, 116, 134, 157], 'Leishmania': [13, 17], '(Leishmania)': [14, 18], 'amazonensis': [15, 47], 'infantum': [19, 30, 105], 'in': [20, 24, 31, 95, 114, 207, 212, 240], 'vitro': [21, 32, 96, 115], ',': [22], 'experimental': [25], 'model': [26], 'L.': [28, 45, 103, 183], '(L.)': [29, 46, 104, 184], '.': [33, 48, 106], 'Initially,': [34], 'LicoA': [35, 49, 78, 92, 110, 152, 191], 'screened': [40], 'promastigote': [42, 98, 117], 'forms': [43, 101, 118, 136], 'was': [50, 79, 93, 141, 165, 199], 'the': [51, 73, 86, 89, 137, 161, 204, 241], 'most': [52], 'active': [53], 'compound,': [54], 'with': [55, 119, 190, 219], 'IC': [56, 74, 120, 138], '50': [57, 75, 121, 139, 163, 193], 'values': [58, 122], '20.26': [60], '3.88': [62], 'μM': [63, 81, 127, 143, 167], 'at': [64, 82, 128, 144, 168, 178, 192], '24': [65, 129], '48': [67, 83, 131, 145, 169], 'h,': [68, 132], 'respectively.': [69], 'Against': [70], 'amastigote': [71, 100, 135], 'forms,': [72], 'value': [76, 140, 164], '36.84': [80], 'h.': [84, 146], 'In': [85], 'next': [87], 'step,': [88], 'effectivity': [90], 'evaluated': [94], 'Results': [107], 'demonstrated': [108, 150], 'that': [109, 151, 226], 'exhibited': [111, 153], 'leishmanicidal': [112], 'activity': [113, 177], '41.10': [124], '12.47': [126], 'respectively;': [133], '29.58': [142], 'Assessment': [147], 'cytotoxicity': [149, 156], 'moderate': [154], 'mammalian': [155], 'peritoneal': [158], 'murine': [159], 'macrophages;': [160], 'CC': [162], '123.21': [166], 'h': [170], 'showed': [172], 'about': [173], '30%': [174], 'hemolytic': [176], 'concentration': [179], '400': [181], 'μM.': [182], 'infantum-': [185], 'infected': [186], 'hamsters': [187], 'treated': [189], 'mg/kg': [194], 'for': [195], 'eight': [196], 'consecutive': [197], 'days': [198], 'able': [200], 'to': [201, 237, 250], 'significantly': [202], 'reduce': [203], 'parasite': [205], 'burden': [206], 'both': [208], 'liver': [209], 'spleen': [211], '43.67': [213], '39.81%,': [215], 'respectively,': [216], 'when': [217], 'compared': [218], 'negative': [220], 'control': [221], 'group.': [222], 'These': [223], 'findings': [224], 'suggest': [225], 'chalcone-type': [227], 'flavonoids': [228], 'can': [229], 'be': [230, 238], 'a': [231], 'promising': [232], 'class': [233], 'natural': [235], 'products': [236], 'considered': [239], 'search': [242], 'new,': [244], 'safe,': [245], 'effective': [247], 'compounds': [248], 'capable': [249], 'treat': [251], 'canine': [252], 'visceral': [253], 'leishmaniosis': [254], '(CVL).': [255]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3111459776', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 2}], 'updated_date': '2024-09-19T12:59:03.185453', 'created_date': '2020-12-21'}