Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3107680699', 'doi': 'https://doi.org/10.3389/fneur.2020.551923', 'title': 'Evidence Limitations in Determining Sexually Dimorphic Outcomes in Pediatric Post-Traumatic Hypopituitarism and the Path Forward', 'display_name': 'Evidence Limitations in Determining Sexually Dimorphic Outcomes in Pediatric Post-Traumatic Hypopituitarism and the Path Forward', 'publication_year': 2020, 'publication_date': '2020-11-26', 'ids': {'openalex': 'https://openalex.org/W3107680699', 'doi': 'https://doi.org/10.3389/fneur.2020.551923', 'mag': '3107680699', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33324312', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7726201'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fneur.2020.551923', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fneur.2020.551923/pdf', 'source': {'id': 'https://openalex.org/S96975567', 'display_name': 'Frontiers in Neurology', 'issn_l': '1664-2295', 'issn': ['1664-2295'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fneur.2020.551923/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5016513396', 'display_name': 'Alina Nico West', 'orcid': 'https://orcid.org/0000-0003-1925-437X'}, 'institutions': [{'id': 'https://openalex.org/I160606119', 'display_name': 'University of Tennessee Health Science Center', 'ror': 'https://ror.org/0011qv509', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I160606119']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alina Nico West', 'raw_affiliation_strings': ['Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, United States'], 'affiliations': [{'raw_affiliation_string': 'Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, United States', 'institution_ids': ['https://openalex.org/I160606119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050243660', 'display_name': 'Alicia Diaz-Thomas', 'orcid': 'https://orcid.org/0000-0002-0168-6855'}, 'institutions': [{'id': 'https://openalex.org/I160606119', 'display_name': 'University of Tennessee Health Science Center', 'ror': 'https://ror.org/0011qv509', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I160606119']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alicia M. Diaz-Thomas', 'raw_affiliation_strings': ['Division of Endocrinology, Department of Pediatrics, University of Tennessee Health Science Center, United States'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology, Department of Pediatrics, University of Tennessee Health Science Center, United States', 'institution_ids': ['https://openalex.org/I160606119']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5016045622', 'display_name': 'Nadeem I. Shafi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I160606119', 'display_name': 'University of Tennessee Health Science Center', 'ror': 'https://ror.org/0011qv509', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I160606119']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nadeem I. Shafi', 'raw_affiliation_strings': ['Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, United States'], 'affiliations': [{'raw_affiliation_string': 'Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, United States', 'institution_ids': ['https://openalex.org/I160606119']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'apc_paid': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'fwci': 0.141, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.247038, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 78, 'max': 80}, 'biblio': {'volume': '11', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10748', 'display_name': 'Insulin-like Growth Factors in Health and Disease', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10748', 'display_name': 'Insulin-like Growth Factors in Health and Disease', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10529', 'display_name': 'Effects of Stress on Brain Function and Health', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/2802', 'display_name': 'Behavioral Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11967', 'display_name': 'Diagnosis and Management of Hyponatremia', 'score': 0.9933, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hypopituitarism', 'display_name': 'Hypopituitarism', 'score': 0.507504}, {'id': 'https://openalex.org/keywords/neuroendocrine-control', 'display_name': 'Neuroendocrine Control', 'score': 0.504279}], 'concepts': [{'id': 'https://openalex.org/C2778491484', 'wikidata': 'https://www.wikidata.org/wiki/Q922411', 'display_name': 'Hypopituitarism', 'level': 2, 'score': 0.7031276}, {'id': 'https://openalex.org/C169900460', 'wikidata': 'https://www.wikidata.org/wiki/Q2200417', 'display_name': 'Cognition', 'level': 2, 'score': 0.51575947}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.47824922}, {'id': 'https://openalex.org/C2781017439', 'wikidata': 'https://www.wikidata.org/wiki/Q1995526', 'display_name': 'Traumatic brain injury', 'level': 2, 'score': 0.44008714}, {'id': 'https://openalex.org/C207886595', 'wikidata': 'https://www.wikidata.org/wiki/Q1456138', 'display_name': 'Pathological', 'level': 2, 'score': 0.4369709}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.42124745}, {'id': 'https://openalex.org/C138496976', 'wikidata': 'https://www.wikidata.org/wiki/Q175002', 'display_name': 'Developmental psychology', 'level': 1, 'score': 0.36588627}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.26164162}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.22317147}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.15544593}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.09413004}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fneur.2020.551923', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fneur.2020.551923/pdf', 'source': {'id': 'https://openalex.org/S96975567', 'display_name': 'Frontiers in Neurology', 'issn_l': '1664-2295', 'issn': ['1664-2295'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/6af42742f4974be1b4b16bc260c1d978', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726201', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33324312', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fneur.2020.551923', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fneur.2020.551923/pdf', 'source': {'id': 'https://openalex.org/S96975567', 'display_name': 'Frontiers in Neurology', 'issn_l': '1664-2295', 'issn': ['1664-2295'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.41, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 151, 'referenced_works': ['https://openalex.org/W1021387213', 'https://openalex.org/W1545440122', 'https://openalex.org/W1788223594', 'https://openalex.org/W1815011115', 'https://openalex.org/W1953578575', 'https://openalex.org/W1966439088', 'https://openalex.org/W1967164782', 'https://openalex.org/W1970255866', 'https://openalex.org/W1970558511', 'https://openalex.org/W1972326895', 'https://openalex.org/W1975474352', 'https://openalex.org/W1977778567', 'https://openalex.org/W1978813592', 'https://openalex.org/W1980217620', 'https://openalex.org/W1981225388', 'https://openalex.org/W1981998396', 'https://openalex.org/W1984943674', 'https://openalex.org/W1985355315', 'https://openalex.org/W1987322500', 'https://openalex.org/W1991040972', 'https://openalex.org/W1991582925', 'https://openalex.org/W1992058795', 'https://openalex.org/W1992265363', 'https://openalex.org/W1994121177', 'https://openalex.org/W1999280329', 'https://openalex.org/W2004073350', 'https://openalex.org/W2005196522', 'https://openalex.org/W2005966256', 'https://openalex.org/W2012043101', 'https://openalex.org/W2014868305', 'https://openalex.org/W2016184699', 'https://openalex.org/W2017953485', 'https://openalex.org/W2017953641', 'https://openalex.org/W2021159550', 'https://openalex.org/W2021208825', 'https://openalex.org/W2021326159', 'https://openalex.org/W2021601561', 'https://openalex.org/W2025943556', 'https://openalex.org/W2027957701', 'https://openalex.org/W2035483698', 'https://openalex.org/W2035800940', 'https://openalex.org/W2038415709', 'https://openalex.org/W2039148071', 'https://openalex.org/W2042179970', 'https://openalex.org/W2042592081', 'https://openalex.org/W2045436441', 'https://openalex.org/W2048103562', 'https://openalex.org/W2049222478', 'https://openalex.org/W2049607038', 'https://openalex.org/W2049746238', 'https://openalex.org/W2054235149', 'https://openalex.org/W2054659813', 'https://openalex.org/W2060719656', 'https://openalex.org/W2061509967', 'https://openalex.org/W2062581271', 'https://openalex.org/W2065926146', 'https://openalex.org/W2069160705', 'https://openalex.org/W2069663854', 'https://openalex.org/W2070497752', 'https://openalex.org/W2072528652', 'https://openalex.org/W2072668066', 'https://openalex.org/W2073434076', 'https://openalex.org/W2077490225', 'https://openalex.org/W2077603659', 'https://openalex.org/W2077970879', 'https://openalex.org/W2078521160', 'https://openalex.org/W2079211198', 'https://openalex.org/W2079266996', 'https://openalex.org/W2089341009', 'https://openalex.org/W2091973725', 'https://openalex.org/W2096333008', 'https://openalex.org/W2096395933', 'https://openalex.org/W2097632478', 'https://openalex.org/W2103564728', 'https://openalex.org/W2104383544', 'https://openalex.org/W2107137258', 'https://openalex.org/W2109931368', 'https://openalex.org/W2110535212', 'https://openalex.org/W2111035027', 'https://openalex.org/W2115976287', 'https://openalex.org/W2120673928', 'https://openalex.org/W2121036968', 'https://openalex.org/W2121854592', 'https://openalex.org/W2123150159', 'https://openalex.org/W2125665709', 'https://openalex.org/W2125967646', 'https://openalex.org/W2126623505', 'https://openalex.org/W2133301528', 'https://openalex.org/W2141464042', 'https://openalex.org/W2149453230', 'https://openalex.org/W2150552625', 'https://openalex.org/W2154379123', 'https://openalex.org/W2163267780', 'https://openalex.org/W2163559038', 'https://openalex.org/W2164237558', 'https://openalex.org/W2166596836', 'https://openalex.org/W2195512504', 'https://openalex.org/W2210815217', 'https://openalex.org/W2232658986', 'https://openalex.org/W2274911843', 'https://openalex.org/W2301703005', 'https://openalex.org/W2319435874', 'https://openalex.org/W2326987135', 'https://openalex.org/W2338590126', 'https://openalex.org/W2338977091', 'https://openalex.org/W2419590095', 'https://openalex.org/W2551995636', 'https://openalex.org/W2588883201', 'https://openalex.org/W2592778466', 'https://openalex.org/W2604392635', 'https://openalex.org/W2606052196', 'https://openalex.org/W2606539517', 'https://openalex.org/W2621986376', 'https://openalex.org/W262751529', 'https://openalex.org/W2762430769', 'https://openalex.org/W2765080371', 'https://openalex.org/W2767718077', 'https://openalex.org/W2788388413', 'https://openalex.org/W2790322976', 'https://openalex.org/W2799889334', 'https://openalex.org/W2802228122', 'https://openalex.org/W2805871423', 'https://openalex.org/W2807543147', 'https://openalex.org/W2810098278', 'https://openalex.org/W2883164881', 'https://openalex.org/W2891121957', 'https://openalex.org/W2896729901', 'https://openalex.org/W2897651473', 'https://openalex.org/W2898773817', 'https://openalex.org/W2900424636', 'https://openalex.org/W2911208202', 'https://openalex.org/W2911566178', 'https://openalex.org/W2914907618', 'https://openalex.org/W2915478013', 'https://openalex.org/W2923531367', 'https://openalex.org/W2925264157', 'https://openalex.org/W2925751533', 'https://openalex.org/W2926840448', 'https://openalex.org/W2940578551', 'https://openalex.org/W2941140846', 'https://openalex.org/W2964275005', 'https://openalex.org/W2981903391', 'https://openalex.org/W2997603215', 'https://openalex.org/W2999792216', 'https://openalex.org/W3004207215', 'https://openalex.org/W3004483333', 'https://openalex.org/W3004492333', 'https://openalex.org/W3005367582', 'https://openalex.org/W3010299545', 'https://openalex.org/W389665830', 'https://openalex.org/W4241790463'], 'related_works': ['https://openalex.org/W789511655', 'https://openalex.org/W2765156354', 'https://openalex.org/W2385034723', 'https://openalex.org/W2342284090', 'https://openalex.org/W2330591497', 'https://openalex.org/W2170244820', 'https://openalex.org/W2078488883', 'https://openalex.org/W2064205118', 'https://openalex.org/W1957551755', 'https://openalex.org/W1788223594'], 'abstract_inverted_index': {'Neuroendocrine': [0], 'dysfunction': [1], 'can': [2, 18], 'occur': [3], 'as': [4], 'a': [5], 'consequence': [6], 'of': [7, 26, 46, 78, 84, 115, 121, 128], 'traumatic': [8], 'brain': [9], 'injury': [10, 85], '(TBI),': [11], 'and': [12, 50, 66, 80, 86, 106, 109], 'disruptions': [13], 'to': [14, 22, 30, 35, 91, 144], 'the': [15, 76, 82, 122, 133], 'hypothalamic-pituitary': [16], 'axis': [17], 'be': [19], 'especially': [20], 'consequential': [21], 'children.': [23], 'The': [24], 'purpose': [25], 'our': [27], 'review': [28], 'is': [29, 52], 'summarize': [31], 'current': [32], 'literature': [33], 'relevant': [34], 'studying': [36], 'sex': [37], 'differences': [38], 'in': [39, 125, 142, 147], 'pediatric': [40], 'post-traumatic': [41], 'hypopituitarism': [42], '(PTHP).': [43], 'Our': [44], 'understanding': [45, 148], 'incidence,': [47], 'time': [48], 'course,': [49], 'impact': [51], 'constrained': [53], 'by': [54, 62], 'studies': [55], 'which': [56, 137], 'are': [57, 60, 112], 'primarily': [58], 'small,': [59], 'disadvantaged': [61], 'significant': [63], 'methodological': [64], 'challenges,': [65], 'have': [67], 'investigated': [68], 'limited': [69], 'temporal': [70], 'windows.': [71], 'Because': [72], 'hormonal': [73], 'changes': [74], 'underpin': [75], 'basis': [77], 'growth': [79], 'development,': [81], 'timing': [83], 'PTHP': [87], 'testing': [88], 'with': [89, 132], 'respect': [90], 'pubertal': [92], 'stage': [93], 'gains': [94], 'particular': [95], 'importance.': [96], 'Reciprocal': [97], 'relationships': [98], 'among': [99], 'neuroendocrine': [100], 'function,': [101], 'TBI,': [102], 'adverse': [103], 'childhood': [104], 'events,': [105], 'physiological,': [107], 'psychological': [108], 'cognitive': [110], 'sequelae': [111], 'underconsidered': [113], 'influencers': [114], 'sexually': [116], 'dimorphic': [117], 'outcomes.': [118], 'In': [119], 'light': [120], 'tremendous': [123], 'heterogeneity': [124], 'this': [126], 'body': [127], 'literature,': [129], 'we': [130, 138], 'conclude': [131], 'common': [134], 'path': [135], 'upon': [136], 'must': [139], 'collectively': [140], 'arrive': [141], 'order': [143], 'make': [145], 'progress': [146], 'PTHP.': [149]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3107680699', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}], 'updated_date': '2024-08-22T17:44:36.467736', 'created_date': '2020-12-07'}