Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3105659513', 'doi': None, 'title': 'TDP-43 induces EMT and promotes hepatocellular carcinoma metastasis via activating Wnt/β-catenin signaling pathway.', 'display_name': 'TDP-43 induces EMT and promotes hepatocellular carcinoma metastasis via activating Wnt/β-catenin signaling pathway.', 'publication_year': 2020, 'publication_date': '2020-01-01', 'ids': {'openalex': 'https://openalex.org/W3105659513', 'mag': '3105659513', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33163270', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7642658'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33163270', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5053061779', 'display_name': 'Feixia Guo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801769982', 'display_name': 'First Affiliated Hospital of Wenzhou Medical University', 'ror': 'https://ror.org/03cyvdv85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801769982']}, {'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Feixia Guo', 'raw_affiliation_strings': ['Precision Medical Center Laboratory, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, Zhejiang Province, China.', 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Precision Medical Center Laboratory, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I2801769982', 'https://openalex.org/I27781120']}, {'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100779538', 'display_name': 'Hongwei Wang', 'orcid': 'https://orcid.org/0000-0003-0697-5100'}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}, {'id': 'https://openalex.org/I2801769982', 'display_name': 'First Affiliated Hospital of Wenzhou Medical University', 'ror': 'https://ror.org/03cyvdv85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801769982']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongwei Wang', 'raw_affiliation_strings': ['Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120', 'https://openalex.org/I2801769982']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101625383', 'display_name': 'Min Jiang', 'orcid': 'https://orcid.org/0000-0002-0932-4904'}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Min Jiang', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083816155', 'display_name': 'Qingguo Yang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qingguo Yang', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040556753', 'display_name': 'Qi Xiang', 'orcid': 'https://orcid.org/0000-0001-9790-5823'}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qi Xiang', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001276099', 'display_name': 'Hongyin Zhou', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongyin Zhou', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012117882', 'display_name': 'Xuemei Hu', 'orcid': 'https://orcid.org/0000-0003-3584-5639'}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xuemei Hu', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037145389', 'display_name': 'Kaixuan Hao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Kaixuan Hao', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066204165', 'display_name': 'Jie Yang', 'orcid': 'https://orcid.org/0000-0002-2240-8504'}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jie Yang', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048696261', 'display_name': 'Hongwen Cao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongwen Cao', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5031118611', 'display_name': 'Zhifa Shen', 'orcid': 'https://orcid.org/0000-0003-4707-8772'}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhifa Shen', 'raw_affiliation_strings': ['Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.'], 'affiliations': [{'raw_affiliation_string': 'Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou 325035, Zhejiang Province, China.', 'institution_ids': ['https://openalex.org/I27781120']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.024, 'has_fulltext': False, 'cited_by_count': 20, 'citation_normalized_percentile': {'value': 0.690713, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '10', 'issue': '10', 'first_page': '3285', 'last_page': '3301'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/beta-catenin', 'display_name': 'Beta-catenin', 'score': 0.49546158}], 'concepts': [{'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.8477607}, {'id': 'https://openalex.org/C173396325', 'wikidata': 'https://www.wikidata.org/wiki/Q1501275', 'display_name': 'Gene knockdown', 'level': 3, 'score': 0.7867993}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.7592182}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.69405425}, {'id': 'https://openalex.org/C76419328', 'wikidata': 'https://www.wikidata.org/wiki/Q74419', 'display_name': 'Epithelial–mesenchymal transition', 'level': 4, 'score': 0.66605484}, {'id': 'https://openalex.org/C30145163', 'wikidata': 'https://www.wikidata.org/wiki/Q384104', 'display_name': 'Catenin', 'level': 4, 'score': 0.6032482}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.49733713}, {'id': 'https://openalex.org/C2779324961', 'wikidata': 'https://www.wikidata.org/wiki/Q1634046', 'display_name': 'Beta-catenin', 'level': 4, 'score': 0.49546158}, {'id': 'https://openalex.org/C2778019345', 'wikidata': 'https://www.wikidata.org/wiki/Q1148337', 'display_name': 'Hepatocellular carcinoma', 'level': 2, 'score': 0.45064223}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.44412374}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39275822}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37686744}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.3641842}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.3265214}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.2824913}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.18623784}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.15069342}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08881116}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33163270', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.83, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 50, 'referenced_works': ['https://openalex.org/W1575439062', 'https://openalex.org/W1959450586', 'https://openalex.org/W1964373656', 'https://openalex.org/W1967137553', 'https://openalex.org/W1967443709', 'https://openalex.org/W1967932847', 'https://openalex.org/W1969489445', 'https://openalex.org/W1970606504', 'https://openalex.org/W1978265813', 'https://openalex.org/W1984145170', 'https://openalex.org/W1985955085', 'https://openalex.org/W1998700667', 'https://openalex.org/W2029492851', 'https://openalex.org/W2036581163', 'https://openalex.org/W2040942754', 'https://openalex.org/W2041643931', 'https://openalex.org/W2045459429', 'https://openalex.org/W2064014317', 'https://openalex.org/W2066952414', 'https://openalex.org/W2069349104', 'https://openalex.org/W2073073462', 'https://openalex.org/W2088751003', 'https://openalex.org/W2105504178', 'https://openalex.org/W2108646620', 'https://openalex.org/W2126422295', 'https://openalex.org/W2127954799', 'https://openalex.org/W2135457495', 'https://openalex.org/W2139267086', 'https://openalex.org/W2142522741', 'https://openalex.org/W2148074532', 'https://openalex.org/W2163403599', 'https://openalex.org/W2169502787', 'https://openalex.org/W2281981495', 'https://openalex.org/W2331292670', 'https://openalex.org/W2419193153', 'https://openalex.org/W2463233151', 'https://openalex.org/W2518422135', 'https://openalex.org/W2530417471', 'https://openalex.org/W2543950675', 'https://openalex.org/W2583642351', 'https://openalex.org/W2595685820', 'https://openalex.org/W2619194747', 'https://openalex.org/W2752950559', 'https://openalex.org/W2756089649', 'https://openalex.org/W2789956212', 'https://openalex.org/W2792389153', 'https://openalex.org/W2811009228', 'https://openalex.org/W2884626935', 'https://openalex.org/W2889646458', 'https://openalex.org/W393883301'], 'related_works': ['https://openalex.org/W4290964239', 'https://openalex.org/W318955610', 'https://openalex.org/W3158129358', 'https://openalex.org/W3138932163', 'https://openalex.org/W3105659513', 'https://openalex.org/W2807440658', 'https://openalex.org/W2778605831', 'https://openalex.org/W2285033765', 'https://openalex.org/W2256109025', 'https://openalex.org/W2092780583'], 'abstract_inverted_index': {'The': [0], 'trans-activation': [1], 'response': [2], 'DNA-binding': [3], 'protein': [4, 12, 130, 142, 162], 'of': [5, 25, 34, 58, 64, 72, 80, 94, 103, 113, 122, 140, 160, 170, 185], '43': [6], 'kDa': [7], '(TDP-43)': [8], 'is': [9], 'a': [10, 179], 'nuclear': [11], 'that': [13, 46, 128, 149], 'has': [14], 'been': [15], 'shown': [16], 'to': [17], 'be': [18], 'involved': [19], 'in': [20, 51], 'the': [21, 32, 68, 78, 95, 101, 114, 120, 138, 153, 158, 166, 183], 'growth': [22], 'and': [23, 29, 55, 62, 70, 88, 108, 136, 168], 'metastasis': [24, 40, 71, 169], 'breast': [26], 'cancer,': [27], 'neuroblastoma,': [28], 'melanoma.': [30], 'However,': [31], 'effect': [33, 102, 121], 'TDP-43': [35, 47, 65, 104, 123, 129, 150], 'on': [36, 106], 'hepatocellular': [37], 'carcinoma': [38], '(HCC)': [39], 'remains': [41], 'unclear.': [42], 'Here,': [43], 'we': [44, 126], 'demonstrated': [45], 'was': [48], 'highly': [49], 'upregulated': [50], 'both': [52], 'clinical': [53], 'samples': [54], 'cell': [56], 'lines': [57], 'HCC.': [59, 187], 'Moreover,': [60], 'knockdown': [61, 105], 'overexpression': [63], 'efficiently': [66], 'affected': [67], 'proliferation': [69, 167], 'HCC': [73, 109, 171], 'cells': [74], 'as': [75, 77, 178], 'well': [76], 'expression': [79], 'some': [81], 'proteins': [82], 'associated': [83], 'with': [84, 133], 'epithelial-mesenchymal': [85], 'transition': [86], '(EMT)': [87], 'Wnt/β-catenin': [89, 96, 115, 154], 'signaling': [90], 'pathway.': [91], 'Furthermore,': [92], 'activation': [93], 'pathway': [97, 116, 155], 'by': [98, 117, 156], 'LiCl': [99], 'restored': [100], 'EMT': [107], 'cells,': [110, 172], 'whereas': [111], 'inhibition': [112, 159], 'XAV939': [118], 'negated': [119], 'overexpression.': [124], 'Importantly,': [125], 'found': [127], 'could': [131], 'interact': [132], 'GSK3β': [134, 141, 161], 'mRNA': [135], 'regulate': [137], 'level': [139], 'translation.': [143], 'Taken': [144], 'together,': [145], 'our': [146], 'findings': [147], 'suggest': [148], 'may': [151], 'activate': [152], 'targeting': [157], 'translation,': [163], 'thus': [164], 'inducing': [165], 'which': [173], 'supports': [174], 'its': [175], 'potential': [176], 'value': [177], 'therapeutic': [180], 'target': [181], 'for': [182], 'treatment': [184], 'metastatic': [186]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3105659513', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 6}], 'updated_date': '2024-12-15T21:58:41.660722', 'created_date': '2020-11-23'}