Diaphragmatic atrophy and dysfunction in critically ill mechanically ventilated children

Name: Work Video:
Duration: 3 min 30 s
Sabyasachi Mistri; Nitin Dhochak; Manisha Jana; Kana Ram Jat; Jhuma Sankar; Sushil K. Kabra; Rakesh Lodha
{'id': 'https://openalex.org/W3087084165', 'doi': 'https://doi.org/10.1002/ppul.25076', 'title': 'Diaphragmatic atrophy and dysfunction in critically ill mechanically ventilated children', 'display_name': 'Diaphragmatic atrophy and dysfunction in critically ill mechanically ventilated children', 'publication_year': 2020, 'publication_date': '2020-09-17', 'ids': {'openalex': 'https://openalex.org/W3087084165', 'doi': 'https://doi.org/10.1002/ppul.25076', 'mag': '3087084165', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32940958'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/ppul.25076', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S144578311', 'display_name': 'Pediatric Pulmonology', 'issn_l': '1099-0496', 'issn': ['1099-0496', '8755-6863'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027960886', 'display_name': 'Sabyasachi Mistri', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I63739035', 'display_name': 'All India Institute of Medical Sciences', 'ror': 'https://ror.org/02dwcqs71', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I63739035']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Sabyasachi Mistri', 'raw_affiliation_strings': ['Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India', 'institution_ids': ['https://openalex.org/I63739035']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044400518', 'display_name': 'Nitin Dhochak', 'orcid': 'https://orcid.org/0000-0002-3676-8930'}, 'institutions': [{'id': 'https://openalex.org/I63739035', 'display_name': 'All India Institute of Medical Sciences', 'ror': 'https://ror.org/02dwcqs71', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I63739035']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Nitin Dhochak', 'raw_affiliation_strings': ['Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India', 'institution_ids': ['https://openalex.org/I63739035']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012500112', 'display_name': 'Manisha Jana', 'orcid': 'https://orcid.org/0000-0001-7449-6596'}, 'institutions': [{'id': 'https://openalex.org/I63739035', 'display_name': 'All India Institute of Medical Sciences', 'ror': 'https://ror.org/02dwcqs71', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I63739035']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Manisha Jana', 'raw_affiliation_strings': ['Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India', 'institution_ids': ['https://openalex.org/I63739035']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004241031', 'display_name': 'Kana Ram Jat', 'orcid': 'https://orcid.org/0000-0003-3642-246X'}, 'institutions': [{'id': 'https://openalex.org/I63739035', 'display_name': 'All India Institute of Medical Sciences', 'ror': 'https://ror.org/02dwcqs71', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I63739035']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Kana R. Jat', 'raw_affiliation_strings': ['Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India', 'institution_ids': ['https://openalex.org/I63739035']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005816703', 'display_name': 'Jhuma Sankar', 'orcid': 'https://orcid.org/0000-0002-9807-6550'}, 'institutions': [{'id': 'https://openalex.org/I63739035', 'display_name': 'All India Institute of Medical Sciences', 'ror': 'https://ror.org/02dwcqs71', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I63739035']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Jhuma Sankar', 'raw_affiliation_strings': ['Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India', 'institution_ids': ['https://openalex.org/I63739035']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047620786', 'display_name': 'Sushil K. Kabra', 'orcid': 'https://orcid.org/0000-0002-8890-8261'}, 'institutions': [{'id': 'https://openalex.org/I63739035', 'display_name': 'All India Institute of Medical Sciences', 'ror': 'https://ror.org/02dwcqs71', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I63739035']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Sushil K. Kabra', 'raw_affiliation_strings': ['Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India', 'institution_ids': ['https://openalex.org/I63739035']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5039572099', 'display_name': 'Rakesh Lodha', 'orcid': 'https://orcid.org/0000-0003-2608-1163'}, 'institutions': [{'id': 'https://openalex.org/I63739035', 'display_name': 'All India Institute of Medical Sciences', 'ror': 'https://ror.org/02dwcqs71', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I63739035']}], 'countries': ['IN'], 'is_corresponding': True, 'raw_author_name': 'Rakesh Lodha', 'raw_affiliation_strings': ['Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India', 'institution_ids': ['https://openalex.org/I63739035']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5039572099'], 'corresponding_institution_ids': ['https://openalex.org/I63739035'], 'apc_list': {'value': 4740, 'currency': 'USD', 'value_usd': 4740, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.142, 'has_fulltext': False, 'cited_by_count': 31, 'citation_normalized_percentile': {'value': 0.840019, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '55', 'issue': '12', 'first_page': '3457', 'last_page': '3464'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10322', 'display_name': 'Respiratory Support and Mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10322', 'display_name': 'Respiratory Support and Mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10549', 'display_name': 'Neonatal Respiratory Health Research', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10867', 'display_name': 'Intensive Care Unit Cognitive Disorders', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/2706', 'display_name': 'Critical Care and Intensive Care Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/interquartile-range', 'display_name': 'Interquartile range', 'score': 0.6519852}, {'id': 'https://openalex.org/keywords/spontaneous-breathing-trial', 'display_name': 'Spontaneous breathing trial', 'score': 0.49946737}, {'id': 'https://openalex.org/keywords/respiratory-rate', 'display_name': 'Respiratory Rate', 'score': 0.4531144}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8783109}, {'id': 'https://openalex.org/C2781172350', 'wikidata': 'https://www.wikidata.org/wiki/Q194520', 'display_name': 'Atrophy', 'level': 2, 'score': 0.7424377}, {'id': 'https://openalex.org/C20463939', 'wikidata': 'https://www.wikidata.org/wiki/Q811123', 'display_name': 'Diaphragmatic breathing', 'level': 3, 'score': 0.73331213}, {'id': 'https://openalex.org/C2777080012', 'wikidata': 'https://www.wikidata.org/wiki/Q3766250', 'display_name': 'Mechanical ventilation', 'level': 2, 'score': 0.7018584}, {'id': 'https://openalex.org/C119060515', 'wikidata': 'https://www.wikidata.org/wiki/Q1916617', 'display_name': 'Interquartile range', 'level': 2, 'score': 0.6519852}, {'id': 'https://openalex.org/C200457457', 'wikidata': 'https://www.wikidata.org/wiki/Q584049', 'display_name': 'Ventilation (architecture)', 'level': 2, 'score': 0.58879673}, {'id': 'https://openalex.org/C2778584172', 'wikidata': 'https://www.wikidata.org/wiki/Q7579051', 'display_name': 'Spontaneous breathing trial', 'level': 3, 'score': 0.49946737}, {'id': 'https://openalex.org/C8213797', 'wikidata': 'https://www.wikidata.org/wiki/Q754250', 'display_name': 'Respiratory rate', 'level': 4, 'score': 0.4531144}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.41802254}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.36158004}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.3416593}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.33991215}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.090927035}, {'id': 'https://openalex.org/C2777953023', 'wikidata': 'https://www.wikidata.org/wiki/Q1073121', 'display_name': 'Heart rate', 'level': 3, 'score': 0.08742663}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/ppul.25076', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S144578311', 'display_name': 'Pediatric Pulmonology', 'issn_l': '1099-0496', 'issn': ['1099-0496', '8755-6863'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Partnerships for the goals', 'id': 'https://metadata.un.org/sdg/17', 'score': 0.48}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W1556450850', 'https://openalex.org/W1898281635', 'https://openalex.org/W1978702633', 'https://openalex.org/W1985256054', 'https://openalex.org/W2019049913', 'https://openalex.org/W2096644147', 'https://openalex.org/W2138697408', 'https://openalex.org/W2149189574', 'https://openalex.org/W2176593277', 'https://openalex.org/W2186752172', 'https://openalex.org/W2188143949', 'https://openalex.org/W2297268244', 'https://openalex.org/W2613713161', 'https://openalex.org/W2749016829', 'https://openalex.org/W2754147990', 'https://openalex.org/W2781362678', 'https://openalex.org/W2794198846', 'https://openalex.org/W2830602399', 'https://openalex.org/W2884980368', 'https://openalex.org/W2888342026', 'https://openalex.org/W2903925660', 'https://openalex.org/W2939873104', 'https://openalex.org/W2963143000', 'https://openalex.org/W2996846296'], 'related_works': ['https://openalex.org/W4386093547', 'https://openalex.org/W4327984426', 'https://openalex.org/W4307282758', 'https://openalex.org/W3045929568', 'https://openalex.org/W3044422173', 'https://openalex.org/W3031745179', 'https://openalex.org/W2921627022', 'https://openalex.org/W2901269754', 'https://openalex.org/W2524056318', 'https://openalex.org/W2344756607'], 'abstract_inverted_index': {'Abstract': [0], 'Rationale': [1], 'The': [2, 237], 'extent': [3], 'of': [4, 26, 33, 42, 62, 83, 96, 162, 176, 246], 'diaphragmatic': [5, 27, 43, 63, 72, 171, 222, 262], 'atrophy': [6, 90, 93, 172, 174, 188, 241], 'and': [7, 39, 68, 71, 85, 87, 92, 106, 135, 146, 173, 180, 226, 229], 'dysfunction': [8], 'in': [9, 23, 98, 156, 192, 221, 231, 249], 'critically': [10, 250], 'ill': [11, 251], 'children': [12, 51, 111, 120], 'from': [13], 'developing': [14], 'countries': [15], 'is': [16], 'not': [17], 'established.': [18], 'Objectives': [19], 'To': [20, 36], 'estimate': [21], 'changes': [22], 'ultrasound': [24], 'measurements': [25, 61], 'thickness': [28, 64], 'over': [29, 158], 'the': [30, 80, 159, 243, 261], 'first': [31, 81, 160, 244], 'week': [32, 82, 161, 245], 'mechanical': [34, 56, 163, 247], 'ventilation.': [35], 'assess': [37], 'magnitude': [38], 'risk': [40], 'factors': [41], 'atrophy.': [44, 263], 'Methods': [45], 'In': [46], 'an': [47], 'observational': [48], 'cohort': [49], 'study,': [50], 'aged': [52], '1–18': [53], 'years,': [54], 'requiring': [55], 'ventilation': [57, 164, 195, 206, 248, 257], 'were': [58, 76, 103, 137], 'included.': [59], 'Ultrasound': [60], 'at': [65], 'end‐expiration': [66], '(DTe)': [67], 'end‐inspiration': [69], '(DTi),': [70], 'thickening': [73], 'fraction': [74], '(DTF)': [75], 'performed': [77], 'daily': [78], 'during': [79, 242], 'admission,': [84], 'pre‐': [86], 'post‐extubation.': [88], 'Diaphragmatic': [89, 187], '(%)': [91], 'rate': [94, 175, 189], '(rate': [95], 'decline': [97], 'DTe,': [99, 133], '%': [100], 'per': [101, 184], 'day)': [102], 'calculated.': [104], 'Measurements': [105], 'Main': [107], 'Results': [108], 'Of': [109, 118], '55': [110], '(74.6%': [112], 'boys)': [113], 'enrolled,': [114], '20': [115], '(36.4%)': [116], 'died.': [117], '35': [119], 'with': [121], 'planned': [122], 'extubation,': [123], '5': [124], '(14.3%)': [125], 'required': [126], 'reintubation.': [127], 'Baseline': [128], 'median': [129, 169], '(interquartile': [130], 'range': [131], '[IQR])': [132], 'DTi,': [134], 'DTF': [136], '1.27': [138], 'mm': [139, 143], '(1,': [140], '1.6),': [141], '1.76': [142], '(1.35,': [144], '2.10),': [145], '33.75%': [147], '(26.90,': [148], '44.60),': [149], 'respectively.': [150, 186], 'There': [151, 217], 'was': [152, 190, 218], 'a': [153], 'significant': [154], 'reduction': [155], 'DTe': [157, 228], '(': [165, 196, 207], 'p': [166, 214], '&lt;': [167], '.001),': [168], '(IQR)': [170], '9.91%': [177], '(5.26,': [178], '17.35)': [179], '2.01%': [181], '(1.08,': [182], '3.04)': [183], 'day,': [185], 'lower': [191], 'pressure': [193], 'targeted': [194, 205], 'n': [197, 208], '=': [198, 209, 215], '44;': [199], '1.79%': [200], '[1.03,': [201], '2.87])': [202], 'than': [203], 'volume': [204], '11;': [210], '3.10%': [211], '[1.31,': [212], '5.49]),': [213], '.038.': [216], 'no': [219], 'difference': [220], 'parameters': [223], '(atrophy': [224], 'rate,': [225], 'peri‐extubation': [227], 'DTF)': [230], 'extubation': [232], 'success': [233], 'versus': [234], 'failure.': [235], 'Conclusions': [236], 'diaphragm': [238], 'undergoes': [239], 'progressive': [240], 'children.': [252], 'Future': [253], 'studies': [254], 'should': [255], 'evaluate': [256], 'strategies': [258], 'to': [259], 'reduce': [260]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3087084165', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 5}], 'updated_date': '2025-01-06T04:06:15.847842', 'created_date': '2020-09-25'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
