Publication Information

{'id': 'https://openalex.org/W3086988082', 'doi': 'https://doi.org/10.1186/s12974-020-01946-7', 'title': 'Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte', 'display_name': 'Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte', 'publication_year': 2020, 'publication_date': '2020-09-11', 'ids': {'openalex': 'https://openalex.org/W3086988082', 'doi': 'https://doi.org/10.1186/s12974-020-01946-7', 'mag': '3086988082', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32917229', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7488511'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12974-020-01946-7', 'pdf_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-020-01946-7', 'source': {'id': 'https://openalex.org/S199572710', 'display_name': 'Journal of Neuroinflammation', 'issn_l': '1742-2094', 'issn': ['1742-2094'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-020-01946-7', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100674204', 'display_name': 'Min Liu', 'orcid': 'https://orcid.org/0000-0002-8117-4808'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Min Liu', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083016192', 'display_name': 'Zhipeng Xu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhipeng Xu', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100447601', 'display_name': 'Long Wang', 'orcid': 'https://orcid.org/0000-0003-3891-0010'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Long Wang', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100350695', 'display_name': 'Lixia Zhang', 'orcid': 'https://orcid.org/0000-0002-9463-6039'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lixia Zhang', 'raw_affiliation_strings': ['Department of Burn and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Burn and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100736974', 'display_name': 'Yi Liu', 'orcid': 'https://orcid.org/0000-0001-8615-5991'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yi Liu', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105711040', 'display_name': 'Jiangbei Cao', 'orcid': 'https://orcid.org/0000-0003-1218-4639'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jiangbei Cao', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065353036', 'display_name': 'Qiang Fu', 'orcid': 'https://orcid.org/0000-0001-6022-8371'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qiang Fu', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100649504', 'display_name': 'Yanhong Liu', 'orcid': 'https://orcid.org/0000-0003-0749-2602'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yanhong Liu', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100348666', 'display_name': 'Hao Li', 'orcid': 'https://orcid.org/0000-0002-9759-2537'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hao Li', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033245701', 'display_name': 'Jingsheng Lou', 'orcid': 'https://orcid.org/0000-0002-0295-5105'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jingsheng Lou', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101579445', 'display_name': 'Wugang Hou', 'orcid': 'https://orcid.org/0000-0001-8307-1741'}, 'institutions': [{'id': 'https://openalex.org/I4210158926', 'display_name': 'Xijing Hospital', 'ror': 'https://ror.org/05cqe9350', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158926']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wugang Hou', 'raw_affiliation_strings': ["Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Air Force Military Medical University, Xi'an, 710032, China"], 'affiliations': [{'raw_affiliation_string': "Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Air Force Military Medical University, Xi'an, 710032, China", 'institution_ids': ['https://openalex.org/I4210158926']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037031307', 'display_name': 'Weidong Mi', 'orcid': 'https://orcid.org/0000-0001-9814-2450'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Weidong Mi', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5053653312', 'display_name': 'Yulong Ma', 'orcid': 'https://orcid.org/0000-0003-0982-9571'}, 'institutions': [{'id': 'https://openalex.org/I2802939634', 'display_name': 'Chinese PLA General Hospital', 'ror': 'https://ror.org/04gw3ra78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802939634']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yulong Ma', 'raw_affiliation_strings': ['Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China'], 'affiliations': [{'raw_affiliation_string': 'Anesthesia and Operation Center, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China', 'institution_ids': ['https://openalex.org/I2802939634']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2390, 'currency': 'GBP', 'value_usd': 2931, 'provenance': 'doaj'}, 'apc_paid': {'value': 2390, 'currency': 'GBP', 'value_usd': 2931, 'provenance': 'doaj'}, 'fwci': 10.197, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 151, 'citation_normalized_percentile': {'value': 0.770867, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '17', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T14144', 'display_name': 'Neurological Disease Mechanisms and Treatments', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13796', 'display_name': 'Neurological Disorders and Treatments', 'score': 0.9776, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/stroke', 'display_name': 'Stroke', 'score': 0.5734288}], 'concepts': [{'id': 'https://openalex.org/C2777542381', 'wikidata': 'https://www.wikidata.org/wiki/Q502961', 'display_name': 'Astrocyte', 'level': 3, 'score': 0.7889839}, {'id': 'https://openalex.org/C2779830541', 'wikidata': 'https://www.wikidata.org/wiki/Q1622829', 'display_name': 'Microglia', 'level': 3, 'score': 0.7484927}, {'id': 'https://openalex.org/C25498285', 'wikidata': 'https://www.wikidata.org/wiki/Q1981368', 'display_name': 'Neuroprotection', 'level': 2, 'score': 0.72562224}, {'id': 'https://openalex.org/C2780495277', 'wikidata': 'https://www.wikidata.org/wiki/Q905442', 'display_name': 'Glial fibrillary acidic protein', 'level': 3, 'score': 0.69373524}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.681039}, {'id': 'https://openalex.org/C2780645631', 'wikidata': 'https://www.wikidata.org/wiki/Q671554', 'display_name': 'Stroke (engine)', 'level': 2, 'score': 0.5734288}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.5484319}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.47793534}, {'id': 'https://openalex.org/C87753298', 'wikidata': 'https://www.wikidata.org/wiki/Q17157137', 'display_name': 'Neuroinflammation', 'level': 3, 'score': 0.4703073}, {'id': 'https://openalex.org/C2776070231', 'wikidata': 'https://www.wikidata.org/wiki/Q14914098', 'display_name': 'TLR4', 'level': 3, 'score': 0.46667778}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.4052336}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.31897366}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.12779191}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.06794307}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12974-020-01946-7', 'pdf_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-020-01946-7', 'source': {'id': 'https://openalex.org/S199572710', 'display_name': 'Journal of Neuroinflammation', 'issn_l': '1742-2094', 'issn': ['1742-2094'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/ac35b5e2f7d042e1909234fd69437123', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488511', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.21203/rs.3.rs-21921/v1', 'pdf_url': 'https://www.researchsquare.com/article/rs-21921/v1.pdf', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12974-020-01946-7', 'pdf_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-020-01946-7', 'source': {'id': 'https://openalex.org/S199572710', 'display_name': 'Journal of Neuroinflammation', 'issn_l': '1742-2094', 'issn': ['1742-2094'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.85}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81971226'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81671039'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81471119'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81801138'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81801193'}], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1572092691', 'https://openalex.org/W160981812', 'https://openalex.org/W1647861543', 'https://openalex.org/W1866068290', 'https://openalex.org/W1975727650', 'https://openalex.org/W1977529472', 'https://openalex.org/W1991495749', 'https://openalex.org/W2011706619', 'https://openalex.org/W2024861314', 'https://openalex.org/W2039602397', 'https://openalex.org/W2059153254', 'https://openalex.org/W2076034559', 'https://openalex.org/W2077186969', 'https://openalex.org/W2086642874', 'https://openalex.org/W2103525815', 'https://openalex.org/W2144324967', 'https://openalex.org/W2274157226', 'https://openalex.org/W2351673993', 'https://openalex.org/W2402881283', 'https://openalex.org/W2572710398', 'https://openalex.org/W2589764628', 'https://openalex.org/W2592378998', 'https://openalex.org/W2620901112', 'https://openalex.org/W2625336672', 'https://openalex.org/W2700330585', 'https://openalex.org/W2775137932', 'https://openalex.org/W2879097257', 'https://openalex.org/W2903346602', 'https://openalex.org/W2946163626', 'https://openalex.org/W2946776998', 'https://openalex.org/W2957360511', 'https://openalex.org/W2982694967', 'https://openalex.org/W4251358128'], 'related_works': ['https://openalex.org/W4281290245', 'https://openalex.org/W3195981340', 'https://openalex.org/W3193914952', 'https://openalex.org/W3107395714', 'https://openalex.org/W2995828647', 'https://openalex.org/W2965172925', 'https://openalex.org/W2886765439', 'https://openalex.org/W2804482952', 'https://openalex.org/W2803817550', 'https://openalex.org/W2076206894'], 'abstract_inverted_index': {'Abstract': [0], 'Background': [1], 'Ischemic': [2], 'stroke': [3, 39, 74, 260], 'is': [4, 57], 'the': [5, 22, 67, 118, 131, 162, 180, 214, 226, 241, 274, 280, 297], 'second': [6], 'leading': [7], 'cause': [8], 'of': [9, 69, 113, 133, 140, 148, 164, 216, 228, 243, 276, 282, 299], 'death': [10], 'globally.': [11], 'The': [12], 'narrow': [13], 'time': [14], 'window': [15], 'for': [16, 24, 63, 96], 'administering': [17], 'effective': [18], 'thrombolytic': [19], 'therapy': [20], 'motivates': [21], 'search': [23], 'alternative': [25], 'prevention': [26, 298], 'strategies.': [27], 'Microglia': [28], 'and': [29, 99, 125, 142, 159, 161, 168, 186, 194, 203, 208, 212, 219, 235, 239, 246, 265, 268, 279], 'astrocyte': [30, 286], 'activation-mediated': [31], 'inflammation': [32], 'play': [33], 'a': [34, 61, 102, 293], 'pivotal': [35], 'role': [36, 68], 'in': [37, 71, 296], 'ischemic': [38, 259, 300], 'injury.': [40], 'Cottonseed': [41], 'oil': [42], '(CSO)': [43], 'has': [44, 75], 'been': [45, 77], 'shown': [46], 'to': [47, 273], 'exert': [48], 'anti-inflammatory': [49], 'effects': [50], 'against': [51, 73], 'peripheral': [52], 'tissue': [53], 'injury,': [54, 124], 'although': [55], 'CSO': [56, 70, 87, 176, 198, 222, 256, 290], 'mostly': [58], 'used': [59], 'as': [60], 'solvent': [62], 'lipid-soluble': [64], 'drugs.': [65], 'However,': [66], 'neuroprotection': [72], 'not': [76], 'previously': [78], 'reported.': [79], 'Methods': [80], 'We': [81, 173], 'treated': [82], 'adult': [83], 'male': [84], 'rats': [85], 'with': [86], '(1.3': [88], 'ml/kg,': [89], 'subcutaneous': [90], 'injection,': [91], 'once': [92], 'every': [93], 'other': [94], 'day': [95], '3': [97], 'weeks)': [98], 'then': [100], 'constructed': [101], 'middle': [103], 'cerebral': [104], 'artery': [105], 'occlusion': [106], '(MCAO)': [107], 'model': [108], 'followed': [109], 'by': [110, 262], '24': [111], 'h': [112], 'reperfusion.': [114], 'Then,': [115], 'we': [116, 128], 'measured': [117, 130], 'neurological': [119, 181], 'scores,': [120], 'infarction': [121, 184], 'volume,': [122, 185], 'neuronal': [123, 188], 'brain': [126, 195], 'edema;': [127], 'also': [129], 'levels': [132, 147], 'pro-inflammatory': [134], 'cytokines': [135], '(IL-1β,': [136], 'IL-6,': [137, 218], 'TNF-α),': [138], 'degree': [139], 'microglial': [141, 202, 264], 'astrocytic': [143, 204, 266], 'activation,': [144, 205, 287], 'protein': [145, 210, 232, 237, 248], 'expression': [146], 'Toll-like': [149], 'receptor': [150], '4': [151], '(TLR4),': [152], 'nuclear': [153], 'factor': [154], 'kappa': [155], 'B': [156], '(NF-κB),': [157], 'C3d': [158, 236], 'S100A10,': [160], 'presence': [163], 'A1': [165, 283], 'type': [166, 170], 'astrocytes': [167], 'A2': [169], 'astrocytes.': [171], 'Results': [172], 'found': [174, 254], 'that': [175, 255, 289], 'treatment': [177, 199, 223, 257], 'significantly': [178, 200, 224], 'improved': [179], 'deficit,': [182], 'reduced': [183, 201, 213], 'alleviated': [187, 258], 'injuries,': [189], 'blood–brain': [190], 'barrier': [191], '(BBB)': [192], 'disruption,': [193], 'edema.': [196], 'Additionally,': [197], 'inhibited': [206], 'TLR4': [207], 'NF-κB': [209], 'expression,': [211, 238], 'release': [215], 'IL-1β,': [217], 'TNF-α.': [220], 'Finally,': [221], 'decreased': [225], 'number': [227, 242], 'C3d/glial': [229], 'fibrillary': [230], 'acidic': [231], '(GFAP)-positive': [233], 'cells': [234, 245], 'increased': [240], 'S100A10/GFAP-positive': [244], 'S100A10': [247], 'expression.': [249], 'Conclusion': [250], 'Our': [251], 'results': [252], 'first': [253], 'injury': [261], 'reducing': [263], 'activation': [267], 'inflammation,': [269], 'which': [270], 'was': [271], 'related': [272], 'inhibition': [275], 'TLR4/NF-κB': [277], 'pathway': [278], 'reduction': [281], 'phenotype': [284], 'neurotoxic': [285], 'suggesting': [288], 'could': [291], 'be': [292], 'new': [294], 'strategy': [295], 'stroke.': [301]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3086988082', 'counts_by_year': [{'year': 2024, 'cited_by_count': 50}, {'year': 2023, 'cited_by_count': 53}, {'year': 2022, 'cited_by_count': 37}, {'year': 2021, 'cited_by_count': 11}], 'updated_date': '2025-01-03T10:14:50.410669', 'created_date': '2020-09-21'}