Relation of Statin Use Prior to Admission to Severity and Recovery Among COVID-19 Inpatients

Name: Work Video:
Duration: 3 min 30 s
Lori B. Daniels; Amy M. Sitapati; Jing Zhang; Jingjing Zou; Quan M. Bui; Junting Ren; Chris Longhurst; Michael H. Criqui; Karen Messer
{'id': 'https://openalex.org/W3086446357', 'doi': 'https://doi.org/10.1016/j.amjcard.2020.09.012', 'title': 'Relation of Statin Use Prior to Admission to Severity and Recovery Among COVID-19 Inpatients', 'display_name': 'Relation of Statin Use Prior to Admission to Severity and Recovery Among COVID-19 Inpatients', 'publication_year': 2020, 'publication_date': '2020-09-16', 'ids': {'openalex': 'https://openalex.org/W3086446357', 'doi': 'https://doi.org/10.1016/j.amjcard.2020.09.012', 'mag': '3086446357', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32946859', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7492151'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.amjcard.2020.09.012', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S185186944', 'display_name': 'The American Journal of Cardiology', 'issn_l': '0002-9149', 'issn': ['0002-9149', '1879-1913'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://doi.org/10.1016/j.amjcard.2020.09.012', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5048308230', 'display_name': 'Lori B. Daniels', 'orcid': 'https://orcid.org/0000-0002-4841-9922'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Lori B. Daniels', 'raw_affiliation_strings': ['Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, California', 'Division of Epidemiology, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Division of Epidemiology, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083544656', 'display_name': 'Amy M. Sitapati', 'orcid': 'https://orcid.org/0000-0002-5737-5925'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Amy M. Sitapati', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100699977', 'display_name': 'Jing Zhang', 'orcid': 'https://orcid.org/0000-0002-1578-3760'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jing Zhang', 'raw_affiliation_strings': ['University of California San Diego Health Moores Cancer Center, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'University of California San Diego Health Moores Cancer Center, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039202077', 'display_name': 'Jingjing Zou', 'orcid': 'https://orcid.org/0000-0002-4749-105X'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jingjing Zou', 'raw_affiliation_strings': ['Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009450324', 'display_name': 'Quan M. Bui', 'orcid': 'https://orcid.org/0000-0001-6070-6978'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Quan M. Bui', 'raw_affiliation_strings': ['Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007542787', 'display_name': 'Junting Ren', 'orcid': 'https://orcid.org/0000-0002-7492-6864'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Junting Ren', 'raw_affiliation_strings': ['Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052938070', 'display_name': 'Chris Longhurst', 'orcid': 'https://orcid.org/0000-0003-4908-6856'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Christopher A. Longhurst', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002475361', 'display_name': 'Michael H. Criqui', 'orcid': 'https://orcid.org/0000-0003-0425-9661'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael H. Criqui', 'raw_affiliation_strings': ['Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, California', 'Division of Epidemiology, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'Division of Epidemiology, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072839298', 'display_name': 'Karen Messer', 'orcid': 'https://orcid.org/0000-0002-9298-2413'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Karen Messer', 'raw_affiliation_strings': ['Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California', 'University of California San Diego Health Moores Cancer Center, University of California San Diego, La Jolla, California'], 'affiliations': [{'raw_affiliation_string': 'University of California San Diego Health Moores Cancer Center, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California', 'institution_ids': ['https://openalex.org/I36258959']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5048308230'], 'corresponding_institution_ids': ['https://openalex.org/I36258959'], 'apc_list': {'value': 3310, 'currency': 'USD', 'value_usd': 3310, 'provenance': 'doaj'}, 'apc_paid': {'value': 3310, 'currency': 'USD', 'value_usd': 3310, 'provenance': 'doaj'}, 'fwci': 3.846, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 163, 'citation_normalized_percentile': {'value': 0.999951, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '136', 'issue': None, 'first_page': '149', 'last_page': '155'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10041', 'display_name': 'COVID-19 Clinical Research Studies', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10041', 'display_name': 'COVID-19 Clinical Research Studies', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11368', 'display_name': 'Long-Term Effects of COVID-19', 'score': 0.995, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10118', 'display_name': 'SARS-CoV-2 and COVID-19 Research', 'score': 0.9876, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.882895}, {'id': 'https://openalex.org/C2776376669', 'wikidata': 'https://www.wikidata.org/wiki/Q5094647', 'display_name': 'Intensive care unit', 'level': 2, 'score': 0.6623715}, {'id': 'https://openalex.org/C167135981', 'wikidata': 'https://www.wikidata.org/wiki/Q2146302', 'display_name': 'Retrospective cohort study', 'level': 2, 'score': 0.6546041}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6163997}, {'id': 'https://openalex.org/C3008058167', 'wikidata': 'https://www.wikidata.org/wiki/Q84263196', 'display_name': 'Coronavirus disease 2019 (COVID-19)', 'level': 4, 'score': 0.6026016}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.595544}, {'id': 'https://openalex.org/C30036603', 'wikidata': 'https://www.wikidata.org/wiki/Q17125150', 'display_name': 'Severity of illness', 'level': 2, 'score': 0.5726955}, {'id': 'https://openalex.org/C2776839432', 'wikidata': 'https://www.wikidata.org/wiki/Q954845', 'display_name': 'Statin', 'level': 2, 'score': 0.56864667}, {'id': 'https://openalex.org/C151956035', 'wikidata': 'https://www.wikidata.org/wiki/Q1132755', 'display_name': 'Logistic regression', 'level': 2, 'score': 0.5606154}, {'id': 'https://openalex.org/C72563966', 'wikidata': 'https://www.wikidata.org/wiki/Q1303415', 'display_name': 'Cohort', 'level': 2, 'score': 0.45586184}, {'id': 'https://openalex.org/C201903717', 'wikidata': 'https://www.wikidata.org/wiki/Q1778788', 'display_name': 'Cohort study', 'level': 2, 'score': 0.4294179}, {'id': 'https://openalex.org/C524204448', 'wikidata': 'https://www.wikidata.org/wiki/Q788926', 'display_name': 'Infectious disease (medical specialty)', 'level': 3, 'score': 0.06904155}], 'mesh': [{'descriptor_ui': 'D057911', 'descriptor_name': 'Angiotensin Receptor Antagonists', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000806', 'descriptor_name': 'Angiotensin-Converting Enzyme Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000073640', 'descriptor_name': 'Betacoronavirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D018352', 'descriptor_name': 'Coronavirus Infections', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D019161', 'descriptor_name': 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D011024', 'descriptor_name': 'Pneumonia, Viral', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057911', 'descriptor_name': 'Angiotensin Receptor Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000806', 'descriptor_name': 'Angiotensin-Converting Enzyme Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000086382', 'descriptor_name': 'COVID-19', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018352', 'descriptor_name': 'Coronavirus Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018352', 'descriptor_name': 'Coronavirus Infections', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D018352', 'descriptor_name': 'Coronavirus Infections', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D003422', 'descriptor_name': 'Critical Care', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006760', 'descriptor_name': 'Hospitalization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019161', 'descriptor_name': 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058873', 'descriptor_name': 'Pandemics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011024', 'descriptor_name': 'Pneumonia, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011024', 'descriptor_name': 'Pneumonia, Viral', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D011024', 'descriptor_name': 'Pneumonia, Viral', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D020127', 'descriptor_name': 'Recovery of Function', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000086402', 'descriptor_name': 'SARS-CoV-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.amjcard.2020.09.012', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S185186944', 'display_name': 'The American Journal of Cardiology', 'issn_l': '0002-9149', 'issn': ['0002-9149', '1879-1913'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://escholarship.org/uc/item/1gn2g6jb', 'pdf_url': 'https://escholarship.org/content/qt1gn2g6jb/qt1gn2g6jb.pdf?t=qpn0wf', 'source': {'id': 'https://openalex.org/S4306400115', 'display_name': 'eScholarship (California Digital Library)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2801248553', 'host_organization_name': 'California Digital Library', 'host_organization_lineage': ['https://openalex.org/I2801248553'], 'host_organization_lineage_names': ['California Digital Library'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492151', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/32946859', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.amjcard.2020.09.012', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S185186944', 'display_name': 'The American Journal of Cardiology', 'issn_l': '0002-9149', 'issn': ['0002-9149', '1879-1913'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.87}], 'grants': [{'funder': 'https://openalex.org/F4320333677', 'funder_display_name': 'Office of the President, University of California', 'award_id': 'R00RG2499'}], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W1909441690', 'https://openalex.org/W1989138522', 'https://openalex.org/W1991622705', 'https://openalex.org/W2009428399', 'https://openalex.org/W2009470002', 'https://openalex.org/W2028521865', 'https://openalex.org/W2068814987', 'https://openalex.org/W2091671824', 'https://openalex.org/W2152165117', 'https://openalex.org/W2156506016', 'https://openalex.org/W2885396126', 'https://openalex.org/W2900829362', 'https://openalex.org/W3009314935', 'https://openalex.org/W3009723094', 'https://openalex.org/W3009799538', 'https://openalex.org/W3009912996', 'https://openalex.org/W3012813927', 'https://openalex.org/W3013231340', 'https://openalex.org/W3015726950', 'https://openalex.org/W3017002108', 'https://openalex.org/W3018087367', 'https://openalex.org/W3019360767', 'https://openalex.org/W3020646040', 'https://openalex.org/W3021992825', 'https://openalex.org/W3023640683', 'https://openalex.org/W3023751598', 'https://openalex.org/W3023838751', 'https://openalex.org/W3028967077', 'https://openalex.org/W3036683212'], 'related_works': ['https://openalex.org/W3162158865', 'https://openalex.org/W2978363435', 'https://openalex.org/W2923497059', 'https://openalex.org/W2593300661', 'https://openalex.org/W2471646736', 'https://openalex.org/W2270619898', 'https://openalex.org/W2129863591', 'https://openalex.org/W2111746513', 'https://openalex.org/W2070622963', 'https://openalex.org/W1596769710'], 'abstract_inverted_index': {'The': [0, 204, 276, 480, 974, 1268, 1327, 1499, 1567, 1691, 1768, 2076, 2136, 3020, 5289, 5359, 5795], 'impact': [1, 277, 5508], 'of': [2, 27, 42, 54, 77, 83, 139, 169, 227, 261, 278, 303, 318, 330, 353, 359, 415, 445, 503, 537, 565, 611, 620, 622, 669, 699, 774, 809, 918, 977, 1000, 1071, 1143, 1145, 1168, 1270, 1275, 1285, 1287, 1312, 1324, 1336, 1347, 1423, 1440, 1512, 1539, 1545, 1564, 1570, 1574, 1669, 1738, 1753, 1765, 1808, 1813, 1836, 1860, 1862, 1896, 1952, 1971, 1997, 2011, 2016, 2147, 2174, 2189, 2191, 2243, 2268, 2276, 2303, 2429, 2503, 2509, 2532, 2589, 2605, 2627, 2654, 2681, 2696, 2715, 2720, 2743, 2764, 2833, 2861, 2888, 2904, 2937, 2961, 3022, 3033, 3105, 3115, 3145, 3206, 3221, 3223, 3236, 3265, 3267, 3290, 3306, 3405, 3411, 3467, 3473, 3478, 3493, 3507, 3543, 3562, 3602, 3617, 3668, 3673, 3678, 3701, 3756, 3802, 3812, 3820, 3852, 3873, 3907, 3966, 3992, 4053, 4075, 4178, 4237, 4269, 4312, 4353, 4382, 4388, 4404, 4416, 4420, 4440, 4499, 4511, 4521, 4531, 4549, 4560, 4592, 4594, 4617, 4659, 4687, 4703, 4706, 4789, 4802, 4912, 4920, 4963, 4966, 4988, 5027, 5036, 5038, 5090, 5177, 5198, 5212, 5262, 5280, 5300, 5405, 5409, 5433, 5446, 5462, 5480, 5484, 5487, 5509, 5526, 5576, 5592, 5644, 5656, 5832], 'statins,': [3, 279, 775, 1288, 1575, 1814, 1998, 2655, 3034, 4359, 5447, 5488, 5510], 'angiotensin-converting': [4, 280, 709, 1072, 1082, 1146, 4595], 'enzyme': [5, 44, 281, 320, 710, 785, 1073, 1083, 1147, 3969, 4056, 4596, 4792], 'inhibitors': [6, 282, 712, 777, 993, 1148, 1816, 2000, 2098, 2722, 2766, 3238, 3509, 4087, 4307, 4553, 4597, 4656, 4793, 5449, 5490], 'and': [7, 19, 57, 92, 109, 127, 182, 209, 265, 283, 295, 333, 368, 385, 403, 458, 485, 541, 575, 585, 679, 707, 741, 780, 844, 846, 882, 951, 981, 994, 1031, 1075, 1149, 1179, 1187, 1247, 1306, 1341, 1454, 1530, 1548, 1559, 1578, 1686, 1747, 1773, 1794, 1811, 1817, 1833, 1843, 1858, 1888, 1916, 1933, 1986, 2001, 2007, 2071, 2086, 2099, 2165, 2281, 2298, 2525, 2542, 2577, 2582, 2591, 2613, 2624, 2640, 2648, 2658, 2837, 2882, 3037, 3110, 3130, 3292, 3317, 3445, 3503, 3609, 3619, 3699, 3727, 3818, 4088, 4180, 4234, 4261, 4284, 4292, 4320, 4373, 4450, 4466, 4554, 4598, 4657, 4684, 4994, 5001, 5122, 5243, 5274, 5283, 5305, 5329, 5342, 5452, 5566, 5578, 5608, 5623, 5659, 5669], 'angiotensin': [8, 284, 940, 1076, 1150, 2386, 2391, 2459, 2464, 3342, 3347, 3377, 3382, 3967, 4054, 4599, 4790, 4795], 'II': [9, 285, 715, 941, 1077, 1151, 2392, 2465, 3348, 3383, 4600, 4796], 'receptor': [10, 286, 716, 792, 922, 1078, 1096, 1152, 2393, 2466, 3349, 3384, 3760, 3815, 4098, 4601, 4797], 'blockers': [11, 287, 717, 1079, 1097, 1153, 4099, 4602, 4683, 4798], '(ARBs)': [12, 288], 'on': [13, 289, 617, 705, 842, 883, 939, 1080, 1255, 1657, 2516, 2521, 2527, 2803, 3077, 3550, 3622, 3735, 4799, 5033, 5302, 5476, 5515], 'coronavirus': [14, 290, 556, 566, 1158, 3707, 4607, 4969], 'disease': [15, 64, 120, 135, 148, 191, 211, 291, 340, 396, 411, 424, 467, 487, 567, 582, 1159, 1298, 1314, 1689, 1810, 1857, 1954, 1985, 2609, 2745, 2836, 2891, 3001, 3090, 3109, 3157, 3225, 3269, 3580, 4442, 4536, 4608, 4970, 5658], '2019': [16, 292, 568, 1160, 4609, 4971], '(COVID-19)': [17, 293], 'severity': [18, 294, 4236, 4559], 'recovery': [20, 155, 186, 195, 231, 270, 296, 431, 462, 471, 507, 546, 1987, 2006, 2094, 2103, 3025, 3067, 3146, 3163, 3277, 3431, 3441, 3589, 4993], 'is': [21, 297, 559, 783, 870, 3594, 4077, 4410, 4423, 4494, 4914, 5060, 5143, 5231, 5362, 5367, 5372], 'important': [22, 298], 'given': [23, 299], 'their': [24, 300], 'high': [25, 301, 594], 'prevalence': [26, 302, 2292, 5197], 'use': [28, 41, 160, 208, 234, 245, 304, 317, 436, 484, 510, 521, 773, 1144, 1286, 1573, 1588, 1637, 1812, 1859, 2073, 2653, 2763, 3032, 3114, 3138, 3177, 3190, 3214, 3425, 3448, 3477, 3506, 3524, 4177, 4233, 4345, 4375, 4390, 4395, 4406, 4422, 4527, 4548, 4593, 4705, 4911, 4987, 5321, 5445, 5461, 5544, 5643], 'among': [29, 66, 187, 271, 305, 342, 463, 547, 1961, 2545, 2907, 2922, 3075, 3149, 3565, 4182, 4922, 5137, 5185, 5558, 5638, 5690, 5834], 'individuals': [30, 306, 4923, 5170], 'at': [31, 81, 307, 357, 592, 744, 1034, 1345, 1508, 1735, 2149, 2171, 2968, 2992, 3475], 'risk': [32, 53, 168, 260, 308, 329, 444, 536, 595, 746, 1036, 2065, 2680, 2742, 2860, 2887, 2903, 2921, 3492, 4439, 4498, 4658, 4686, 4801, 4919, 5004, 5062, 5135, 5655], 'for': [33, 69, 100, 194, 219, 253, 309, 345, 376, 470, 495, 529, 561, 596, 747, 1037, 1157, 1278, 1334, 1394, 1451, 1493, 1542, 1555, 1560, 1778, 1791, 1798, 1827, 1883, 1908, 1983, 2049, 2096, 2105, 2423, 2496, 2651, 2852, 2895, 2994, 3132, 3162, 3312, 3471, 3499, 3504, 3537, 3555, 3598, 3892, 4309, 4463, 4606, 5006, 5064, 5088, 5319, 5333, 5383, 5420, 5428, 5465, 5606, 5620, 5641, 5667], 'severe': [34, 55, 61, 119, 132, 147, 170, 190, 210, 263, 274, 310, 331, 337, 395, 408, 423, 446, 466, 486, 539, 550, 598, 1297, 1313, 1325, 1695, 1715, 1730, 1766, 1772, 1809, 1856, 1953, 1984, 2012, 2156, 2181, 2194, 2220, 2335, 2424, 2438, 2497, 2548, 2565, 2569, 2608, 2628, 2682, 2717, 2744, 2835, 2862, 2890, 2905, 3028, 3084, 3089, 3156, 3224, 3268, 3315, 3495, 3546, 3563, 3579, 4000, 4354, 4441, 4500, 4535, 5007, 5065, 5192, 5303, 5657], 'COVID-19.': [35, 70, 311, 346, 781, 1723, 3547, 5468], 'We': [36, 71, 312, 347, 1464, 1616, 1905, 1993, 2209, 5402, 5469, 5581], 'studied': [37, 313], 'the': [38, 47, 215, 247, 314, 323, 491, 523, 562, 791, 810, 880, 919, 998, 1226, 1248, 1283, 1310, 1359, 1504, 1523, 1581, 1593, 1598, 1601, 1611, 1626, 1643, 1650, 1702, 1709, 1736, 1806, 1876, 1897, 1948, 1964, 1968, 1995, 2030, 2050, 2056, 2093, 2102, 2172, 2177, 2192, 2228, 2249, 2430, 2504, 2617, 2625, 2652, 2662, 2672, 2712, 2757, 2782, 2804, 2830, 2935, 2947, 2957, 2995, 3004, 3060, 3080, 3103, 3123, 3279, 3406, 3412, 3461, 3556, 3560, 3623, 3702, 3728, 3757, 3870, 3908, 3913, 4310, 4380, 4386, 4417, 4430, 4434, 4490, 4685, 4800, 4986, 5130, 5174, 5194, 5210, 5226, 5244, 5263, 5278, 5284, 5316, 5326, 5340, 5417, 5431, 5443, 5460, 5485, 5498, 5507, 5537, 5552, 5559, 5597, 5815], 'association': [39, 205, 315, 481, 1284, 1804, 1996, 2843, 3021, 3104, 3451, 3538, 4545], 'between': [40, 88, 206, 316, 364, 482, 771, 1338, 1771, 1805, 1913, 2621, 2880, 4176, 4546, 5120, 5339], 'statin/angiotensin-converting': [43, 319], 'inhibitors/ARB': [45, 321], 'in': [46, 137, 214, 322, 413, 490, 806, 876, 879, 924, 979, 1201, 1252, 1397, 1430, 1469, 1619, 1649, 1919, 2028, 2055, 2092, 2101, 2453, 2616, 2671, 2711, 2746, 2811, 2829, 2847, 2956, 2976, 3002, 3056, 3270, 3325, 3371, 3420, 3491, 3559, 3604, 3636, 3670, 3732, 3782, 3848, 3899, 3972, 4059, 4135, 4288, 4314, 4379, 4424, 4433, 4447, 4468, 4489, 4509, 4719, 5009, 5129, 5173, 5200, 5225, 5325, 5336, 5356, 5376, 5430, 5625, 5672, 5818, 5837], 'month': [48, 324], 'before': [49, 325], 'hospital': [50, 326, 1320, 1606, 1710, 2533], 'admission,': [51, 327, 1547, 1607, 2517], 'with': [52, 58, 166, 232, 257, 328, 334, 442, 508, 533, 579, 701, 739, 786, 1029, 1154, 1293, 1781, 1865, 1936, 2003, 2040, 2067, 2113, 2120, 2144, 2154, 2168, 2179, 2218, 2248, 2288, 2547, 2568, 2607, 2678, 2703, 2741, 2754, 2808, 2821, 2858, 2884, 2901, 2919, 3030, 3112, 3141, 3203, 3218, 3263, 3276, 3285, 3302, 3409, 3429, 3485, 3527, 3539, 4120, 4185, 4285, 4362, 4443, 4603, 4916, 4924, 4968, 5013, 5093, 5113, 5124, 5149, 5187, 5497, 5541, 5652, 5826, 5848, 5856, 5864], 'outcome,': [56, 332, 2182, 2758, 3280], 'time': [59, 128, 143, 153, 184, 229, 268, 335, 404, 419, 429, 460, 505, 544, 1308, 1737, 1949, 2004, 2008, 2173, 2970, 2997, 3023, 3065, 3087, 3313, 3318, 3530, 3575, 3587, 4364, 4383, 4512, 4532, 5152, 5175, 5599, 5662], 'to': [60, 115, 118, 129, 146, 154, 162, 177, 185, 199, 230, 240, 251, 269, 336, 391, 394, 405, 422, 430, 438, 453, 461, 475, 506, 516, 527, 545, 614, 942, 945, 1004, 1012, 1184, 1225, 1281, 1296, 1309, 1316, 1389, 1436, 1459, 1473, 1585, 1605, 1624, 1654, 1701, 1719, 1743, 1850, 1854, 1901, 1946, 1950, 1956, 2005, 2009, 2539, 2562, 2574, 2667, 2691, 2699, 2709, 2727, 2735, 2786, 2827, 2868, 2886, 2914, 2931, 2951, 2999, 3024, 3027, 3066, 3088, 3101, 3167, 3182, 3195, 3230, 3243, 3254, 3314, 3319, 3460, 3481, 3531, 3545, 3553, 3578, 3588, 3901, 3912, 3989, 3999, 4347, 4358, 4365, 4384, 4427, 4481, 4513, 4518, 4533, 4557, 4991, 5030, 5153, 5168, 5191, 5351, 5381, 5436, 5459, 5505, 5517, 5539, 5585, 5604, 5648, 5663, 5682, 5813], 'outcome': [62, 338, 1693, 1716, 2032, 2157, 2783, 2863, 3107, 3125, 3316], 'or': [63, 122, 339, 398, 713, 778, 1291, 1300, 1315, 1613, 1681, 1704, 1732, 1756, 1763, 1955, 1977, 2159, 2258, 2290, 2729, 2767, 3026, 3119, 3248, 3510, 4537, 4551, 4558, 5450, 5478, 5491, 5513, 5806], 'recovery,': [65, 341, 1317, 1957, 3291, 3320, 4385, 4514, 5664], 'patients': [67, 79, 272, 343, 355, 548, 624, 700, 738, 1028, 1276, 1332, 1468, 1485, 1618, 1892, 2142, 2195, 2269, 2305, 2563, 2788, 2909, 2950, 2989, 3469, 3566, 4183, 4405, 4967, 5040, 5092, 5295, 5562, 5639], 'hospitalized': [68, 80, 99, 344, 356, 375, 1277, 1333, 1450, 1633, 1886, 1891, 2143, 2806, 2949, 3470, 3572, 4184, 5294, 5640], 'performed': [72, 348, 2799, 2941], 'a': [73, 258, 266, 349, 534, 542, 696, 768, 850, 871, 1510, 1561, 1614, 1647, 1714, 1782, 1822, 1834, 1848, 1909, 2020, 2036, 2145, 2155, 2180, 2219, 2274, 2454, 2583, 2587, 2704, 2751, 2770, 2822, 2877, 2982, 3042, 3127, 3286, 3303, 3372, 3437, 3486, 3513, 3540, 3599, 3705, 4190, 4351, 4397, 4401, 4413, 4437, 4461, 4505, 4711, 4917, 5061, 5134, 5150, 5158, 5223, 5312, 5334, 5363, 5368, 5374, 5400, 5587, 5618, 5653, 5660, 5838], 'retrospective': [74, 350], 'single-center': [75, 351, 1272, 5674], 'study': [76, 352, 1274, 1328, 1500, 2138, 5265, 5439, 5500, 5530], 'all': [78, 354, 1331, 1441, 1484, 1556, 2087, 2106, 2110, 3571, 5593], 'University': [82, 358, 1346], 'California': [84, 360, 1348], 'San': [85, 361, 1349, 2977], 'Diego': [86, 362, 1350], 'Health': [87, 363, 1351], 'February': [89, 365, 1339, 1902, 2962], '10,': [90, 366], '2020': [91, 95, 367, 371, 1344, 2964], 'June': [93, 369, 1342], '17,': [94, 370, 1343], '(n': [96, 372, 1461, 2310, 2313, 2965, 3329, 3332], '=': [97, 103, 221, 373, 379, 497, 1462, 2311, 2314, 2385, 2390, 2396, 2400, 2405, 2411, 2415, 2420, 2458, 2463, 2469, 2473, 2478, 2484, 2488, 2493, 2871, 2893, 2966, 3170, 3185, 3198, 3233, 3246, 3257, 3330, 3333, 3341, 3346, 3352, 3356, 3361, 3365, 3376, 3381, 3387, 3391, 3396, 3400, 3433, 3443, 3453], '170': [98, 374, 2141, 3468], 'COVID-19,': [101, 264, 377, 540, 1494, 3496, 5193, 5642], 'n': [102, 378, 2308], '5,281': [104, 380], 'COVID-negative': [105, 216, 381, 492, 1565, 1634, 1885, 1890, 2213, 2805, 2816, 2926, 2948, 4451, 5131, 5293, 5360, 5594], 'controls).': [106, 382], 'Logistic': [107, 383], 'regression': [108, 384, 1879, 2024, 2058, 2801, 3098, 3310, 4492, 5841], 'competing': [110, 386, 1923, 2031, 2064, 3043, 3124, 3323, 3514, 5803], 'risks': [111, 387, 1924, 3044, 3515], 'analyses': [112, 388, 1631, 2062, 2066, 2130, 3408, 4369], 'were': [113, 389, 1415, 1445, 1449, 1491, 1552, 1572, 1622, 1717, 1741, 1748, 1846, 1868, 1894, 1988, 2043, 2047, 2131, 2184, 2226, 2242, 2270, 2512, 2520, 2571, 2579, 2598, 2610, 2615, 2630, 2669, 2737, 2760, 2778, 2819, 2856, 2925, 2954, 3013, 3457, 4118, 4376, 5207, 5583], 'used': [114, 390, 1945, 2027, 3100, 3568, 5403], 'investigate': [116, 392, 1282, 1947, 2934, 3102], 'progression': [117, 393, 1295, 3544], '(death': [121, 397, 1299], 'intensive': [123, 399, 1301], 'care': [124, 400, 1302, 2991], 'unit': [125, 401, 1303], 'admission),': [126, 402, 1305], 'discharge': [130, 406, 1321], 'without': [131, 189, 273, 407, 465, 549, 1322, 1711, 2564], 'disease.': [133, 275, 409, 551, 1326, 1767, 2013, 2498, 2718, 5178], 'Severe': [134, 410, 552], 'occurred': [136, 412], '53%': [138, 414, 3081], 'COVID-positive': [140, 416, 1418, 1557, 1802, 1962, 2223, 2304, 2848, 2908, 3326, 4449, 5138, 5327, 5341, 5835], 'inpatients.': [141, 417, 5139], 'Median': [142, 418, 2530], 'from': [144, 420, 625, 1522, 1708, 1722, 1870, 3147, 3576, 5041, 5569], 'hospitalization': [145, 421, 3577, 5406], 'was': [149, 156, 164, 212, 224, 255, 425, 432, 440, 488, 500, 531, 1280, 1421, 1435, 1501, 1515, 1589, 1638, 1694, 1819, 1881, 1944, 1967, 2026, 2033, 2080, 2125, 2231, 2535, 2543, 2675, 2701, 2784, 2839, 2844, 2876, 2899, 2917, 2972, 3039, 3068, 3073, 3091, 3099, 3139, 3200, 3209, 3215, 3259, 3283, 3294, 3300, 3426, 3483, 3519, 3525, 3534, 3581, 3590, 4349, 4360, 4391, 4445, 4528, 5117, 5147, 5182, 5322, 5331, 5396, 5650], '2': [150, 426, 557, 2018, 2166, 3092, 3583, 3970, 4057], 'days;': [151, 427], 'median': [152, 428, 3064, 3086, 3574, 3586], '7': [157, 433, 3069, 3591], 'days.': [158, 434, 3093, 3592], 'Statin': [159, 435, 1199, 3137, 3424, 3634, 3780, 4133], 'prior': [161, 250, 437, 526, 1472, 1584, 1604, 1653, 1900, 2666, 2698, 3480, 4346, 5014, 5435, 5647], 'admission': [163, 252, 439, 528, 1474, 1655, 1700, 2668, 2700, 3482, 4348, 5649], 'associated': [165, 256, 441, 532, 2677, 2702, 2740, 2820, 2857, 2900, 2918, 3140, 3202, 3217, 3262, 3284, 3301, 3428, 3484, 3500, 3526, 4119, 4361, 4915, 5148, 5651], 'reduced': [167, 443, 3219, 3288, 3304, 3541, 4121, 4918, 5654], 'COVID-19': [171, 254, 447, 530, 615, 673, 730, 748, 1038, 1202, 1249, 1279, 1337, 1425, 1438, 1460, 1527, 1914, 1975, 2148, 2570, 2629, 2683, 3029, 3148, 3474, 3605, 3637, 3729, 3783, 4093, 4136, 4803, 5010, 5031, 5066, 5412, 5518, 5691], '(adjusted': [172, 192, 235, 448, 468, 511, 2684], 'OR': [173, 449, 2419, 2492], '0.29,': [174, 450], '95%CI': [175, 197, 238, 451, 473, 514, 2689, 2725, 2733, 2866, 2912, 2929, 3165, 3180, 3193, 3228, 3241, 3252], '0.11': [176, 452], '0.71,': [178, 454], 'p': [179, 201, 455, 477, 2114, 2122, 2558, 2870, 3169, 3184, 3197, 3232, 3245, 3256], '<': [180, 202, 456, 478, 2115, 2123], '0.01)': [181, 457], 'faster': [183, 228, 267, 459, 504, 543, 3430, 3529, 4363, 5661], 'those': [188, 464, 2546, 2567, 2606, 2923, 2952, 3076, 5186, 5540], 'HR': [193, 236, 469, 512, 3160, 3364, 3399, 4623], '2.69,': [196, 472, 3164], '1.36': [198, 474, 3166], '5.33,': [200, 476, 3168], '0.01).': [203, 479], 'statin': [207, 244, 483, 520, 3052, 3213, 3523, 4232, 4374, 4394, 5320, 5645, 5685], 'smaller': [213, 489, 2603], 'cohort': [217, 493, 5132, 5202, 5361], '(p': [218, 494, 2850, 2892, 3432, 3442, 3452], 'interaction': [220, 496, 1911, 2853, 2879, 5119], '0.07).': [222, 498, 2854], 'There': [223, 499, 3208, 3593, 5116], 'potential': [225, 501, 1828, 2052, 2771, 3133, 4079, 5069], 'evidence': [226, 502, 1254, 2840, 3211, 3296, 3521, 3536, 3734, 5218, 5332], 'ARB': [233, 509, 2072, 2389, 2462, 2659, 3120, 3176, 3345, 3380, 3435, 4343, 4372, 4389, 4421], '1.92,': [237, 513, 3179], '0.81': [239, 515, 3181], '4.56).': [241, 517], 'In': [242, 518, 1479, 1629, 2750, 2873, 3172, 3464, 3512, 3797, 4114, 4337, 4367, 4523, 5104, 5345, 5636], 'conclusion,': [243, 519], 'during': [246, 522, 1487, 1600, 5596], '30': [248, 524, 1582, 1602, 1651, 2664], 'days': [249, 525, 1583, 1603, 1652, 2665, 3070], 'lower': [259, 535], 'developing': [262, 538, 597, 2716, 2834, 2889, 3494], 'acute': [553, 5467], 'respiratory': [554, 4001], 'syndrome': [555, 564], '(SARS-CoV-2)': [558], 'responsible': [560], 'clinical': [563, 4982, 5678], '(COVID-19),': [569], 'which': [570, 794, 947, 1845, 2029, 2969, 3994, 4715, 5270, 5275, 5366, 5424, 5520, 5601], 'has': [571, 720, 948, 3995, 5532], 'caused': [572], 'significant': [573, 1910, 2878, 4402, 4506], 'morbidity': [574], 'mortality': [576, 612, 4181, 4263, 4921, 5028], 'worldwide.': [577], 'Individuals': [578], 'underlying': [580], 'cardiovascular': [581, 726, 2412, 2485, 3362, 3397], '(CVD),': [583], 'hypertension,': [584, 1664, 1840, 2277, 2645], 'diabetes': [586, 742, 1032, 1684, 2590, 5002], 'have': [587, 1015, 1180, 1744, 3896, 4542, 4709, 5473, 5573, 5800, 5811], 'been': [588, 721, 1733, 3897, 3996], 'identified': [589], 'as': [590, 790, 799, 801, 1098, 1177, 1319, 1353, 1417, 1495, 1608, 1667, 1698, 2035, 2054, 2348, 2445, 2756, 2960, 3126, 3278, 3322, 3612, 3614, 4085, 4100, 4265, 5127, 5189, 5311, 5416], 'groups': [591], 'particularly': [593], 'COVID-19.1Ruan': [599], 'Q': [600, 650, 4752, 4849, 5016], 'Yang': [601, 3929, 4016, 4733, 4747, 4765, 4828, 4868, 4870, 4888, 5017], 'K': [602, 1237, 3651, 3663, 3717, 3916, 4003, 4158, 4257, 5018], 'Wang': [603, 3941, 4028, 4759, 4777, 4878, 4902, 4953, 4957, 5019], 'W': [604, 666, 966, 3934, 4021, 4170, 4857, 5020], 'Jiang': [605, 651, 3959, 4046, 5021], 'L': [606, 732, 888, 896, 1022, 1137, 3936, 4023, 4154, 4304, 4586, 4819, 4831, 4835, 4845, 4855, 4871, 4950, 5022], 'Song': [607, 4832, 5023], 'J': [608, 644, 648, 902, 1057, 1205, 1926, 3640, 3786, 3834, 4139, 4160, 4168, 4220, 4662, 4690, 4728, 4738, 4766, 4784, 4841, 4869, 4889, 4901, 4905, 4907, 4956, 5024, 5247], 'Clinical': [609, 4228, 5025, 5086], 'predictors': [610, 5026], 'due': [613, 2998, 5029, 5167], 'based': [616, 1656, 5032], 'an': [618, 784, 803, 1398, 2522, 2528, 2794, 2942, 3142, 3751, 5034, 5118], 'analysis': [619, 2753, 2802, 2945, 5035, 5291, 5538], 'data': [621, 1356, 1739, 5037, 5454, 5475], '150': [623, 5039], 'Wuhan,': [626, 5042], 'China.Intensive': [627, 5043], 'Care': [628, 5044], 'Med.': [629, 751, 1041, 3977, 4064, 4663, 4691, 5045], '2020;': [630, 682, 752, 855, 929, 1042, 1104, 1163, 1208, 1260, 1406, 3643, 3740, 3789, 4106, 4142, 4612, 4664, 4692, 4805, 4927, 4974, 5046, 5071, 5096], '46:': [631, 5047], '846-848Crossref': [632, 5048], 'PubMed': [633, 690, 760, 864, 932, 987, 1050, 1088, 1107, 1211, 1263, 1409, 3646, 3686, 3743, 3792, 3861, 3882, 3981, 4068, 4109, 4145, 4198, 4247, 4279, 4332, 4474, 4667, 4695, 4936, 5049, 5074, 5099, 5256, 5631], 'Scopus': [634, 691, 761, 865, 933, 988, 1051, 1089, 1108, 1170, 1212, 1264, 1410, 3647, 3687, 3744, 3793, 3862, 3883, 3982, 4069, 4110, 4146, 4199, 4248, 4280, 4333, 4475, 4619, 4668, 4696, 4808, 4937, 4977, 5050, 5075, 5100, 5257, 5632], '(3221)': [635, 5051], 'Google': [636, 693, 763, 867, 935, 990, 1053, 1091, 1110, 1172, 1214, 1266, 1412, 3649, 3689, 3746, 3795, 3864, 3885, 3984, 4071, 4112, 4148, 4201, 4250, 4282, 4335, 4477, 4621, 4670, 4698, 4810, 4939, 4979, 5052, 5077, 5102, 5259, 5634], 'Scholar,2Zheng': [637], 'Z': [638, 1121, 1229, 3709, 3942, 4029, 4570, 4754, 4863, 4960], 'Peng': [639, 647, 4763, 4864], 'F': [640, 904, 1243, 3723, 3924, 4011, 4674, 4724, 4732, 4825, 4839, 5085], 'Xu': [641, 4751, 4848], 'B': [642, 894, 3769, 3926, 3938, 4013, 4025, 4212, 4259, 4294, 4742, 4861], 'Zhao': [643, 4820, 4890], 'Liu': [645, 655, 3837, 3939, 3945, 3955, 4026, 4032, 4042, 4725, 4775, 4854, 4866, 4894], 'H': [646, 664, 815, 892, 973, 3838, 3922, 4009, 4255, 4298, 4730, 4734, 4756, 4786, 4829, 4875, 4909, 4954], 'Li': [649, 4729, 4785, 4908], 'C': [652, 658, 835, 3958, 3960, 4045, 4047, 4627, 4748, 4873], 'Zhou': [653, 4838, 4840], 'Y': [654, 662, 3830, 3918, 3928, 3932, 3946, 4005, 4015, 4019, 4033, 4649, 4772, 4778, 4823, 4859, 4903, 4944], 'S': [656, 817, 823, 837, 914, 1119, 1131, 1196, 1378, 3631, 3655, 3777, 3920, 4007, 4130, 4174, 4568, 4580, 4625, 4641], 'Ye': [657, 4850], 'Zhang': [659, 3931, 3937, 4018, 4024, 4739, 4769, 4779, 4872, 4884, 4886, 4892, 4949], 'P': [660, 1123, 3930, 4017, 4164, 4206, 4572, 4780, 4851, 4893], 'Xing': [661], 'Guo': [663, 3831, 3923, 4010, 4906], 'Tang': [665], 'Risk': [667], 'factors': [668, 5005], 'critical': [670], '&': [671, 5712, 5728, 5745, 5754, 5764, 5778, 5793], 'mortal': [672], 'cases:': [674], 'A': [675, 831, 1115, 1133, 1245, 1922, 1928, 2187, 2602, 3725, 3950, 3963, 4037, 4050, 4156, 4317, 4564, 4582, 4635, 5140], 'systematic': [676, 4318, 5524], 'literature': [677], 'review': [678, 4319, 5395], 'meta-analysis.J': [680], 'Infect.': [681, 4323], '81:': [683, 1105, 4107], 'e16-e25Abstract': [684], 'Full': [685, 687, 755, 757, 859, 861, 1045, 1047, 4274, 4276, 4327, 4329, 4931, 4933], 'Text': [686, 688, 756, 758, 860, 862, 1046, 1048, 4275, 4277, 4328, 4330, 4932, 4934], 'PDF': [689, 759, 863, 1049, 4278, 4331, 4935], '(1447)': [692], 'Scholar': [694, 764, 868, 936, 991, 1173, 1215, 1267, 1413, 1943, 3690, 3747, 3796, 3886, 3985, 4072, 4113, 4283, 4336, 4478, 4699, 4980, 5103, 5260, 5635], 'Because': [695], 'large': [697, 5588], 'proportion': [698, 2585, 2604], 'these': [702, 725, 1007, 1920, 2017, 2200, 2596, 2747, 3271, 4707, 4989, 5453, 5463], 'conditions': [703, 1661, 1838, 2287, 2642, 3502, 5671], 'are': [704, 1758, 1776, 2117, 3054, 3418, 4984, 5003, 5011, 5503, 5680], 'statins': [706, 1217, 2515, 2697, 2818, 3479, 3603, 3804, 4082, 4117, 4179, 4913, 5301, 5347], 'either': [708, 1699, 1729, 1972, 4534, 4555], '(ACE)': [711], 'angiotensinogen': [714], '(ARBs),': [718], 'there': [719, 1420, 2183, 2838, 2875, 2971, 3293, 3518, 3533, 5330], 'speculation': [722], 'about': [723], 'whether': [724, 5684], 'medications': [727, 1008, 1471, 1861, 4708, 4990, 5464, 5577, 5686], 'may': [728, 766, 996, 1009, 1218, 3008, 3692, 3868, 5156, 5221, 5387, 5493, 5687], 'influence': [729, 5814], 'risk.3Fang': [731], 'Karakiulakis': [733, 1023], 'G': [734, 827, 970, 1024, 1198, 3633, 3653, 3779, 3940, 4027, 4132, 4651, 4672, 4678, 4680, 4764, 4853, 4865, 5079], 'Roth': [735, 1025], 'M': [736, 813, 906, 1026, 1127, 1192, 1194, 1231, 1233, 1235, 1380, 1382, 1930, 3627, 3629, 3659, 3711, 3713, 3715, 3773, 3775, 3944, 4031, 4126, 4128, 4453, 4576, 4676, 4744, 4837, 4867, 4946, 5081, 5610], 'Are': [737, 1027], 'hypertension': [740, 1030, 2091, 2592], 'mellitus': [743, 1033], 'increased': [745, 1035, 2679, 2859, 2902, 3143, 3204, 3440, 4497, 5114], 'infection?.Lancet': [749, 1039], 'Respir': [750, 1040], '8:': [753, 1043], 'e21Abstract': [754, 1044], '(2013)': [762, 1052], 'ACE2': [765, 782, 843, 869, 923, 937, 978, 1176, 3618, 3669, 3891, 3903, 3914, 3986, 4076, 5227], 'be': [767, 1477, 1720, 1851, 2575, 3009, 5166, 5349, 5388, 5457, 5494], 'mechanistic': [769], 'link': [770], 'CVD,': [772, 2280, 2647], 'ACE': [776, 992, 1289, 1576, 1815, 1999, 2069, 2097, 2457, 2523, 2656, 2721, 2765, 3035, 3117, 3188, 3237, 3446, 3508, 4086, 4525, 4552, 4722, 5448, 5489, 5511], 'ARBs,': [779, 1292], 'multiple': [787, 5068], 'roles,': [788], 'serving': [789], 'through': [793, 3606, 3754, 3810], 'SARS-CoV-2': [795, 838, 921, 1100, 1220, 3694, 4102], 'enters': [796], 'human': [797, 925, 2416, 2489], 'cells,': [798], 'well': [800, 3613, 4084], 'playing': [802], 'integral': [804], 'part': [805, 1895], 'countering': [807], 'activation': [808, 3755], 'renin-angiotensin-angiotensinogen': [811], 'system.4Hoffmann': [812], 'Kleine-Weber': [814], 'Schroeder': [816], 'Kruger': [818], 'N': [819, 1113, 4172, 4296, 4562, 5054], 'Herrler': [820, 826], 'T': [821, 908, 910, 1239, 3719, 3952, 4039, 4458, 4942, 4952, 5615], 'Erichsen': [822], 'Schiergens': [824], 'TS': [825], 'Wu': [828, 4741, 4947], 'NH': [829], 'Nitsche': [830], 'Muller': [832], 'MA': [833], 'Drosten': [834], 'Pohlmann': [836], 'Cell': [839, 915], 'Entry': [840], 'Depends': [841], 'TMPRSS2': [845], 'Is': [847], 'Blocked': [848], 'by': [849, 1355, 1503, 1610, 1761, 2082, 2306, 2988, 3051, 3675, 3696, 3844], 'Clinically': [851], 'Proven': [852], 'Protease': [853], 'Inhibitor.Cell.': [854], '181': [856], '(e278):': [857], '271-280Abstract': [858], '(12600)': [866], 'membrane-bound': [872], 'aminopeptidase': [873], 'expressed': [874], 'broadly': [875, 5389], 'humans,': [877], 'including': [878, 1632, 1830, 2151, 2215, 2643, 5292], 'heart': [881, 1682], 'lung': [884, 3975, 4062, 4094], 'alveolar': [885], 'epithelial': [886], 'cells.5Nicin': [887], 'Abplanalp': [889], 'WT': [890], 'Mellentin': [891], 'Kattih': [893], 'Tombor': [895], 'John': [897], 'D': [898, 1094, 1241, 3721, 3836, 3948, 3956, 4035, 4043, 4096, 4302, 4647, 4746, 4760, 4879], 'Schmitto': [899], 'JD': [900, 4637, 5237], 'Heineke': [901], 'Emrich': [903], 'Arsalan': [905], 'Holubec': [907], 'Walther': [909], 'Zeiher': [911], 'AM': [912], 'Dimmeler': [913], 'type-specific': [916], 'expression': [917, 999, 3817, 3826, 3904], 'putative': [920], 'hearts.Eur': [926], 'Heart': [927, 1204, 3639, 3785, 4138], 'J.': [928], '41:': [930], '1804-1806Crossref': [931], '(207)': [934], 'acts': [938], 'form': [943], 'angiotensin-(1': [944], '7)': [946], 'anti-inflammatory,': [949], 'anti-fibrotic,': [950], 'vasodilatory': [952], 'effects.6Hamming': [953], 'I': [954], 'Cooper': [955], 'ME': [956], 'Haagmans': [957], 'BL': [958, 4218], 'Hooper': [959], 'NM': [960], 'Korstanje': [961], 'R': [962, 1376, 2134, 4166, 4897], 'Osterhaus': [963], 'AD': [964], 'Timens': [965], 'Turner': [967], 'AJ': [968], 'Navis': [969], 'van': [971], 'Goor': [972], 'emerging': [975, 5126], 'role': [976, 3601, 3677, 3965, 4052, 5224], 'physiology': [980], 'disease.J': [982], 'Pathol.': [983], '2007;': [984, 4271], '212:': [985], '1-11Crossref': [986], '(334)': [989], 'ARBs': [995, 1579, 1818, 2002, 2730, 2768, 2855, 3038, 3249, 4444, 4550, 4720, 5451, 5492, 5514], 'increase': [997, 1010], 'ACE2,': [1001], 'leading': [1002], 'some': [1003, 3210, 3295, 3595, 4516, 5217, 5384, 5483], 'speculate': [1005], 'that': [1006, 2841, 3212, 3297, 3522, 4412, 4485, 4999, 5144, 5219, 5377, 5386, 5555, 5798, 5809], 'susceptibility': [1011, 4556, 5516], 'COVID-19;': [1013], 'others': [1014], 'postulated': [1016], 'protective': [1017, 2772, 3600, 5128], 'effects': [1018, 1183, 3549, 3611, 3621, 4268, 5111, 5299, 5486], 'via': [1019, 1222, 1519, 3615, 5545], 'anti-inflammatory': [1020, 3608], 'actions.3Fang': [1021], 'Scholar,7Ferrario': [1054], 'CM': [1055], 'Jessup': [1056], 'Chappell': [1058, 3943, 4030], 'MC': [1059], 'Averill': [1060], 'DB': [1061], 'Brosnihan': [1062], 'KB': [1063], 'Tallant': [1064], 'EA': [1065], 'Diz': [1066], 'DI': [1067], 'Gallagher': [1068], 'PE': [1069], 'Effect': [1070, 3455], 'inhibition': [1074, 3700, 3811], 'cardiac': [1081], '2.Circulation.': [1084], '2005;': [1085, 3978, 4065], '111:': [1086], '2605-2610Crossref': [1087], '(1238)': [1090], 'Scholar,': [1092, 1111, 4202, 4251, 4811, 4940], '8Gurwitz': [1093], 'Angiotensin': [1095, 4097], 'tentative': [1099, 4101], 'therapeutics.Drug': [1101, 4103], 'Dev': [1102, 4104], 'Res.': [1103, 4105], '537-540Crossref': [1106, 4108], '(597)': [1109, 4111], '9Mehta': [1112], 'Kalra': [1114, 4563], 'Nowacki': [1116, 4565], 'AS': [1117, 3954, 4041, 4566], 'Anjewierden': [1118, 4567], 'Han': [1120, 4569], 'Bhat': [1122, 4571], 'Carmona-Rubio': [1124, 4573], 'AE': [1125, 4574], 'Jacob': [1126, 4575], 'Procop': [1128, 4577], 'GW': [1129, 4578], 'Harrington': [1130, 4579], 'Milinovich': [1132, 4581], 'Svensson': [1134, 4583], 'LG': [1135, 4584], 'Jehi': [1136, 4585], 'Young': [1138, 4587], 'JB': [1139, 4588], 'Chung': [1140, 4589], 'MK': [1141, 4590], 'Association': [1142, 4175, 4591], 'testing': [1155, 4604, 5525], 'positive': [1156, 1424, 1974, 4605, 5411], '(COVID-19).JAMA': [1161, 4610, 4972], 'Cardiol.': [1162, 4611, 4973], 'May': [1164, 4613], '5': [1165, 4614], '(Online': [1166, 4615], 'ahead': [1167, 4616], 'print)e201855https://doi.org/10.1001/jamacardio.2020.1855Crossref': [1169, 4618], '(314)': [1171, 4620], 'Statins': [1174, 1246, 3691, 3726, 3867], 'upregulate': [1175], 'well,': [1178], 'additional': [1181, 2795, 2943], 'pleotropic': [1182], 'counter': [1185], 'inflammation': [1186], 'oxidative': [1188], 'stress.10Castiglione': [1189], 'V': [1190, 3625, 3661, 3771, 4124], 'Chiriaco': [1191, 3626, 3772, 4125], 'Emdin': [1193, 3628, 3774, 4127], 'Taddei': [1195, 3630, 3776, 4129], 'Vergaro': [1197, 3632, 3778, 4131], 'therapy': [1200, 3635, 3781, 4134], 'infection.Eur': [1203, 3638, 3784, 4137], 'Cardiovasc': [1206, 3641, 3787, 4140], 'Pharmacother.': [1207, 3642, 3788, 4141], '6:': [1209, 3644, 3790, 3880, 4143, 4245], '258-259Crossref': [1210, 3645, 3791, 4144], '(51)': [1213, 3648, 3794, 4147, 4809], 'Further,': [1216], 'block': [1219], 'infectivity': [1221, 3695], 'direct': [1223, 1256, 3620, 3697, 3736], 'binding': [1224, 3698, 3906], 'main': [1227, 1250, 3703, 3730], 'protease.11Reiner': [1228], 'Hatamipour': [1230, 3710], 'Banach': [1232, 3712], 'Pirro': [1234, 3714], 'Al-Rasadi': [1236, 3716], 'Jamialahmadi': [1238, 3718], 'Radenkovic': [1240, 3720], 'Montecucco': [1242, 3722], 'Sahebkar': [1244, 3724], 'protease:': [1251, 3731], 'silico': [1253, 3733], 'interaction.Arch': [1257, 3737], 'Med': [1258, 1403, 3738], 'Sci.': [1259, 3739], '16:': [1261, 3741], '490-496Crossref': [1262, 3742], '(200)': [1265, 3745], 'purpose': [1269], 'this': [1271, 1488, 1871, 2842, 3465, 3807, 5201, 5213, 5371, 5673, 5819], 'observational': [1273, 4115, 4469, 4540, 4701, 5268, 5626, 5675], 'inhibitors,': [1290, 1577, 2657, 3036, 5512], '(1)': [1294, 1884], '[ICU]': [1304], '(2)': [1307, 1889], 'onset': [1311, 1951, 2010], 'defined': [1318, 1697, 2347, 2444], 'development': [1323, 2626, 3222, 3266], 'population': [1329, 2139, 2336, 2439, 5591], 'included': [1330, 1483, 1525, 1662, 2063, 2140, 2293, 2637, 2670], 'treatment': [1335, 3472, 4311], '10': [1340, 3338], '(UCSDH),': [1352], 'ascertained': [1354], 'capture': [1357], 'within': [1358, 1580, 2661], 'system-wide': [1360], 'electronic': [1361, 3005], 'health': [1362, 1391, 1400, 3006], 'record': [1363, 3007], '(EHR)': [1364], 'system': [1365, 4655, 4682], '(Epic': [1366], 'Systems,': [1367], 'Verona,': [1368], 'Wisconsin).12Reeves': [1369], 'JJ': [1370, 4736, 4815], 'Hollandsworth': [1371], 'HM': [1372], 'Torriani': [1373], 'FJ': [1374, 4253], 'Taplitz': [1375], 'Abeles': [1377], 'Tai-Seale': [1379], 'Millen': [1381], 'Clay': [1383], 'BJ': [1384], 'Longhurst': [1385], 'CA': [1386], 'Rapid': [1387], 'response': [1388, 3764, 3809, 3823], 'COVID-19:': [1390], 'informatics': [1392], 'support': [1393, 4517], 'outbreak': [1395], 'management': [1396], 'academic': [1399], 'system.J': [1401], 'Am': [1402], 'Inform': [1404], 'Assoc.': [1405], '27:': [1407], '853-859Crossref': [1408], '(267)': [1411], 'Patients': [1414, 1444, 1706, 1724, 1864, 2039], 'designated': [1416], 'if': [1419, 1447, 1592, 1642, 5414], 'history': [1422, 1668, 2275, 2588], 'polymerase': [1426], 'chain': [1427], 'reaction.': [1428], 'Beginning': [1429], 'mid-March': [1431], '2020,': [1432], 'UCSDH': [1433, 1898, 2958, 2993], 'policy': [1434], 'ascertain': [1437], 'status': [1439, 1731, 1746, 1867, 1915, 2042, 2170], 'admitted': [1442, 1486], 'patients.': [1443, 1566, 5358, 5692], 'excluded': [1446, 1466, 1617], 'they': [1448, 3895, 5799], 'reasons': [1452], 'unrelated,': [1453], 'exhibited': [1455], 'no': [1456, 3450, 4544, 5801], 'symptoms': [1457, 5434], 'attributable,': [1458], '28).': [1463], 'also': [1465, 1639, 1906, 2044, 2210, 2779, 3216, 5165, 5296, 5373, 5470, 5531, 5582], '21': [1467], 'whom': [1470, 1620, 3003], 'could': [1475, 5164, 5810], 'not': [1476, 1727, 2599, 2738, 3014, 3153, 3260, 4350, 4529, 5426, 5441, 5456, 5472], 'verified.': [1478], 'sensitivity': [1480, 1630, 1874, 2061, 2752, 2796, 2944, 3407, 5290], 'analyses,': [1481, 1875, 2111, 5423], 'we': [1482, 1621, 2798, 2940, 4503, 5306, 5502, 5550], 'timeframe': [1489], 'who': [1490, 1725, 1893, 2163, 2924, 2953, 3062, 3082, 3151, 3567], 'negative': [1492, 1497, 4482, 5589], 'contemporaneous': [1496], 'controls.': [1498], 'approved': [1502], 'Institutional': [1505], 'Review': [1506, 5711, 5727, 5744, 5753, 5763, 5777, 5792], 'Board': [1507], 'UCSD;': [1509], 'waiver': [1511], 'informed': [1513], 'consent': [1514], 'granted.': [1516], 'Data': [1517, 1551, 5703, 5723], 'collected': [1518], 'automatic': [1520], 'extraction': [1521], 'EHR': [1524], 'demographics,': [1526], 'test': [1528, 1976, 5413], 'dates': [1529, 1538, 1544], 'results,': [1531], 'past': [1532, 2663], 'medical': [1533, 5579], 'diagnoses,': [1534], 'outpatient': [1535, 3031, 3113, 4547], 'medication': [1536, 1599, 1627, 1636, 2660, 3414, 4344, 5481, 5543, 5646], 'history,': [1537], 'hospitalization,': [1540, 1543], 'reason': [1541], 'ICU': [1546, 1703, 2197, 2787], 'vital': [1549], 'status.': [1550], 'verified': [1553], 'manually': [1554], 'patients,': [1558, 1635, 1803, 1887, 2202, 2224, 3573], 'random': [1562], 'sample': [1563, 5287], 'primary': [1568, 1692, 2137, 2507, 3462], 'exposures': [1569, 2508, 3415], 'interest': [1571], 'admission.': [1586, 2198], 'Medication': [1587], 'considered': [1590, 1640, 1718, 1742, 1847, 2126, 4341], 'present': [1591, 1641, 5264, 5499], 'patient': [1594, 1612, 1644, 2622], 'had': [1595, 1645, 1726, 2273, 2279, 2283, 2586, 3152, 5109], 'regularly': [1596], 'taken': [1597], 'reported': [1609, 2118, 5817], 'caregiver.': [1615], 'unable': [1623, 5504], 'verify': [1625], 'history.': [1628, 5580], 'filled': [1646], 'prescription': [1648], 'dispense': [1658], 'data.': [1659], 'Comorbid': [1660], 'obesity,': [1663, 2644, 5123], 'CVD': [1665, 2410, 2483, 3360, 3395, 5353], '(defined': [1666], 'coronary': [1670], 'artery': [1671], 'disease,': [1672, 1680, 1696, 2566, 3085, 4355, 4501], 'stroke': [1673], 'and/or': [1674, 2246, 2260], 'transient': [1675], 'ischemic': [1676], 'attack,': [1677], 'peripheral': [1678], 'arterial': [1679], 'failure),': [1683], 'mellitus,': [1685], 'chronic': [1687, 2401, 2406, 2474, 2479, 3357, 3392, 3845], 'kidney': [1688, 2402, 2475, 3358, 3393], '(CKD).': [1690], 'death.': [1705], 'discharged': [1707, 1734], 'ever': [1712], 'experiencing': [1713], 'recovered': [1721], 'reached': [1728], 'lock': [1740], 'unresolved': [1745, 1866, 2041, 2169], 'censored.': [1749, 2045], 'For': [1750, 2014, 2109], 'each': [1751, 1779, 1917, 2015, 3106, 3410], 'predictor': [1752, 4352], 'interest,': [1754, 2510], 'means': [1755], 'proportions': [1757], 'presented,': [1759], 'stratified': [1760, 3050], 'presence': [1762, 1807, 2426, 2500], 'absence': [1764, 2428, 2502], 'mean': [1769, 2333, 2436], 'difference': [1770, 2334, 2437, 5335], 'non-severe': [1774], 'subjects': [1775, 3150], 'presented': [1777], 'predictor,': [1780], '95%': [1783], 'confidence': [1784, 2397, 2470, 3353, 3388], 'interval': [1785], '(CI)': [1786], 'computed': [1787], 'using': [1788, 1821, 1990, 2133, 2632, 3041], 't': [1789], 'tests': [1790, 1797], 'continuous': [1792], 'variables': [1793, 2088], "Fisher's": [1795], 'exact': [1796], 'categorical': [1799], 'variables.': [1800], 'Among': [1801, 2222, 2264, 2815, 3059, 3079, 3570], 'investigated': [1820, 1994, 2631, 3040], 'multivariable': [1823, 2633, 4368, 5839], 'logistic': [1824, 1878, 2057, 2634, 2800, 4435, 4491, 5840], 'regression,': [1825], 'adjusting': [1826, 3131, 5666], 'confounders': [1829, 2053, 3134], 'age,': [1831, 2638], 'sex,': [1832, 2639], 'list': [1835], 'comorbid': [1837, 2265, 2286, 2641, 3501, 5670], '(obesity,': [1839], 'diabetes,': [1841, 2646], 'CKD': [1842, 2296, 2399, 2472, 3355, 3390], 'CVD)': [1844], 'priori': [1849], 'potentially': [1852], 'related': [1853], 'both': [1855, 4371, 4407, 4448], 'interest.': [1863], 'omitted': [1869], 'analysis.': [1872, 2059, 2175, 3045, 3463], 'As': [1873, 2793, 4400], 'same': [1877, 2051, 5598], 'model': [1880, 2025, 2095, 2104, 3672, 4381], 'fit': [1882], 'registry': [1899], '1,': [1903, 2963], '2020.': [1904], 'checked': [1907], 'term': [1912], 'variable': [1918], 'models.': [1921, 2749, 3273], 'analysis13Beyersmann': [1925], 'Allignol': [1927], 'Schumacher': [1929], 'Competing': [1931], 'Risks': [1932], 'Multistate': [1934], 'Models': [1935, 2046], 'R.': [1937], 'xi.': [1938], 'Springer,': [1939], 'New': [1940], 'York2012:': [1941], '245Google': [1942], 'whichever': [1958], 'came': [1959], 'first,': [1960], 'patients;': [1963], 'starting': [1965], 'timepoint': [1966, 5419], 'earliest': [1969], 'date': [1970, 5404, 5408], 'first': [1973, 2996, 5410], 'hospitalization.': [1978, 5437], 'Cause-specific': [1979, 3046], 'cumulative': [1980, 3047], 'incidence': [1981, 3048], 'curves': [1982], 'calculated': [1989], 'Aalen-Johansen': [1991], 'estimators.': [1992], 'outcomes,': [2019, 5304], 'Cox': [2021, 3095], 'proportional': [2022, 2077, 3096], 'hazards': [2023, 2078, 3097], 'treated': [2034, 3321], 'censoring': [2037, 3128], 'event.': [2038], 'adjusted': [2048, 2713, 2748, 2831, 3159, 3173, 3272], 'Additional': [2060], 'statin,': [2068, 3116], 'inhibitor,': [2070], 'modelled': [2074], 'separately.': [2075], 'assumption': [2079], 'tested': [2081], 'examining': [2083], 'Schoenfeld': [2084], 'residuals': [2085], 'passed': [2089], 'except': [2090, 2762], 'obesity': [2100, 2883, 2898, 5000, 5125], '3': [2107, 3413], 'drugs.': [2108], 'associations': [2112], '0.10': [2116], 'along': [2119], '95%CIs;': [2121], '0.05': [2124], 'statistically': [2127, 2600], 'significant.': [2128, 2601], 'All': [2129], 'conducted': [2132], 'v3.4.4.': [2135], 'diagnosis': [2146], 'UCSDH,': [2150, 3476], '90': [2152, 2178, 2193], '(53%)': [2153], '(ICU': [2158], 'death),': [2160], '78': [2161], '(46%)': [2162], 'recovered,': [2164, 3063], '(1%)': [2167], 'Of': [2176, 2199], '22': [2185], 'deaths.': [2186], 'total': [2188], '88': [2190, 2201, 3825], 'required': [2196, 2205], '61': [2203], '(69%)': [2204], 'invasive': [2206, 2790], 'mechanical': [2207, 2791], 'ventilation.': [2208, 2792], 'analyzed': [2211], '5281': [2212], 'subjects,': [2214], '1278': [2216], '(24%)': [2217], 'outcome.': [2221], '58%': [2225], 'male;': [2227], 'average': [2229], 'age': [2230, 3282, 5146], '59': [2232], '±': [2233, 2330, 2340, 2342, 2433], '19': [2234], 'years': [2235], '(Table': [2236, 2593, 3135], '1).': [2237, 2694, 2776], 'Just': [2238], 'over': [2239], 'half': [2240], '(55%)': [2241], 'Hispanic': [2244], 'race': [2245, 2262], 'ethnicity,': [2247], 'remainder': [2250], 'non-Hispanic': [2251, 2611], 'white': [2252], '(21%),': [2253], 'African-American': [2254], '(6%),': [2255], 'Asian': [2256], '(5%),': [2257], 'other': [2259, 4431], 'mixed': [2261], '(12%).': [2263], 'conditions,': [2266], '56%': [2267], 'obese,': [2271, 2578], '44%': [2272], '21%': [2278, 2519, 2823], '20%': [2282], 'diabetes.': [2284], 'Other': [2285], '5%': [2289], 'greater': [2291, 2584], 'asthma': [2294], '(8%),': [2295], '(18%),': [2297], 'cancer': [2299], '(14%).Table': [2300], '1Baseline': [2301], 'characteristics': [2302, 2623], 'outcomeOutcomeCharacteristic': [2307], '(%)Mild': [2309], '80)Severe': [2312], '90)OR95%CIpMen44': [2315], '(55%)54': [2316], '(60%)1.230.64-2.360.54Black5': [2317], '(6%)5': [2318], '(6%)0.880.20-4.001.00Non-Hispanic': [2319], 'white19': [2320], '(24%)17': [2321], '(19%)0.750.33-1.670.46Asian4': [2322], '(5%)5': [2323], '(6%)1.120.23-5.841.00Hispanic45': [2324], '(56%)49': [2325], '(54%)0.930.48-1.780.88Other/mixed7': [2326], '(9%)14': [2327], '(16%)1.910.68-5.940.24Age': [2328], '(years)*Mean': [2329], 'standard': [2331, 2434], 'deviation;': [2332, 2435], '-': [2337, 2440, 4316], 'mild': [2338, 2441, 5188], 'population.58.7': [2339], '19.960.1': [2341], '17.31.44-4.24-7.120.62Current': [2343], 'smoker7': [2344], '(9%)1': [2345], '(1%)0.120.00-0.960.03Obesity†Obesity': [2346], 'body': [2349, 2446], 'mass': [2350, 2447], 'index': [2351, 2448], '≥30': [2352, 2449], 'kg/m2.41': [2353], '(51%)54': [2354], '(60%)1.420.74-2.740.28Diabetes': [2355], 'mellitus12': [2356], '(15%)22': [2357], '(24%)1.830.79-4.400.18Hypertension32': [2358], '(40%)43': [2359], '(48%)1.370.71-2.640.35CVD17': [2360], '(21%)18': [2361], '(20%)0.930.41-2.090.85Heart': [2362], 'failure4': [2363], '(5%)8': [2364], '(9%)1.850.47-8.730.38Stroke5': [2365], '(6%)4': [2366], '(4%)0.700.13-3.380.74CKD13': [2367], '(16%)17': [2368], '(19%)1.200.50-2.910.69Asthma4': [2369], '(5%)9': [2370], '(10%)2.100.56-9.740.26COPD3': [2371], '(4%)4': [2372, 2376], '(4%)1.190.20-8.401.00Cancer12': [2373], '(15%)11': [2374], '(12%)0.790.29-2.100.66HIV3': [2375], '(4%)1.190.20-8.401.00Statin26': [2377], '(32%)20': [2378], '(22%)0.600.28-1.240.17ACE': [2379], 'inhibitor15': [2380], '(19%)20': [2381], '(22%)1.240.55-2.830.70ARB8': [2382], '(10%)12': [2383], '(13%)1.380.49-4.140.63ACE': [2384], 'converting': [2387, 2460, 3343, 3378, 3968, 4055, 4791], 'enzyme;': [2388, 2461, 3344, 3379], 'blocker;': [2394, 2467, 3350, 3385], 'CI': [2395, 2468, 3351, 3386], 'interval;': [2398, 2471, 3354, 3389], 'disease;': [2403, 2409, 2413, 2476, 2482, 2486, 3359, 3363, 3394, 3398], 'COPD': [2404, 2477, 4262], 'obstructive': [2407, 2480], 'pulmonary': [2408, 2481], 'HIV': [2414, 2487], 'immunodeficiency': [2417, 2490], 'virus;': [2418, 2491], 'odds': [2421, 2494, 2685, 2714, 2832], 'ratio': [2422, 2495, 2686], 'disease.Comparing': [2425], 'vs': [2427, 2501, 2552], 'characteristic.': [2431, 2505], 'Mean': [2432], 'population.†': [2442], 'Obesity': [2443, 5059], 'kg/m2.': [2450], 'Open': [2451, 3369], 'table': [2452, 3370], 'new': [2455, 3373], 'tab': [2456, 3374], 'Comparing': [2499], 'Considering': [2506, 3274], '27%': [2511], 'actively': [2513], 'taking': [2514], 'while': [2518, 3585, 4393], 'inhibitor': [2524, 3118, 3189, 3447, 4526], '12%': [2526], 'ARB.': [2529], 'length': [2531], 'stay': [2534], '9.7': [2536], '(IQR': [2537], '3.9': [2538], '19.7)': [2540], 'days,': [2541, 2554, 3584], 'higher': [2544, 4438], 'infection': [2549], '(median': [2550], '16.8': [2551], '5.0': [2553], 'Wilcoxon': [2555], 'rank': [2556], 'sum': [2557], 'value': [2559, 2851], '<0.001).': [2560], 'Compared': [2561], 'more': [2572, 2614, 3487, 4717, 5159, 5183], 'likely': [2573], 'male': [2576, 3298, 5106], 'slightly': [2580], 'older,': [2581], '1),': [2594], 'although': [2595], 'differences': [2597], 'white,': [2612], 'category': [2618], '"other/mixed."': [2619], 'Associations': [2620], 'regression.': [2635], 'Covariates': [2636], 'CKD.': [2649], 'Indicators': [2650], 'model.': [2673, 5842], 'Diabetes': [2674], 'independently': [2676], '[aOR]': [2687], '3.36,': [2688], '1.14': [2690], '10.87)': [2692], '(Figure': [2693], 'Use': [2695, 2719, 3235], '71%': [2705], 'reduction': [2706, 2824, 3490, 3558], '(95%CI': [2707, 2825], '29%': [2708], '89%)': [2710], '(aOR': [2723, 2731, 2864, 2910, 2927], '1.31,': [2724], '0.55': [2726], '3.19)': [2728], '1.77,': [2732], '0.60': [2734], '5.59)': [2736], 'significantly': [2739, 3201, 3261, 3287], 'death': [2755, 5833], 'results': [2759, 2809], 'similar': [2761, 3459, 4357], 'showed': [2769, 3449, 5297], 'effect': [2773, 4387, 4419, 4508, 4520, 5317, 5337], '(Appendix': [2774, 3017], 'Figure': [2775, 3057, 5829], 'Results': [2777, 3012, 3404], 'unchanged': [2780], 'when': [2781, 4340, 4370], 'limited': [2785], 'requiring': [2789], 'analysis,': [2797, 3517, 4339], 'population,': [2807, 5161], 'summarized': [2810], 'Appendix': [2812, 3421, 5828], 'Table': [2813, 3018], '1.': [2814, 5830], 'inpatients,': [2817], '7%': [2826], '34%)': [2828], 'weaker': [2845, 3535], 'than': [2846, 3488, 4721], 'inpatients': [2849, 5595, 5836], '1.35,': [2865], '1.11': [2867], '1.65,': [2869], '0.003.)': [2872], 'addition,': [2874, 5105, 5346], 'COVID-status': [2881, 5121], 'respect': [2885], '0.03': [2894], 'interaction).': [2896], 'Although': [2897, 3887, 5179, 5391], 'outcomes': [2906, 3564, 4287, 4965, 5008, 5354, 5689], '1.50,': [2911], '0.76': [2913], '3.01)': [2915], 'it': [2916, 4409, 5163, 5378], 'decreased': [2920], '0.94,': [2928], '0.82': [2930], '1.07).': [2932], 'To': [2933], 'possibility': [2936, 5279], 'misclassification': [2938, 5398, 5553], 'bias,': [2939], 'limiting': [2946, 2986], 'already': [2955], 'Registry': [2959], '1,313)': [2967], 'little': [2973], 'COVID': [2974], 'circulating': [2975], 'Diego.': [2978], 'This': [2979, 4479, 5155, 5529], 'subpopulation': [2980], 'represents': [2981], 'well-characterized': [2983], 'cohort,': [2984, 5328], 'thus': [2985], 'confounding': [2987, 4465, 4488, 5310, 5607, 5622], 'seeking': [2990], 'COVID-related': [3000], 'less': [3010], 'reliable.': [3011], 'materially': [3015], 'changed': [3016], '2).': [3019, 3136], 'curves,': [3049], 'use,': [3053], 'displayed': [3055], '2.': [3058], '46%': [3061], 'overall,': [3071], 'but': [3072, 4356, 5133], 'shorter': [3074, 5151], 'statins.': [3078, 3569, 4428], 'developed': [3083], 'Multivariable': [3094], '(severe': [3108], 'recovery)': [3111], 'medication,': [3121], 'treating': [3122, 5466], 'event': [3129], 'rate': [3144, 3205, 3220, 3264, 3289, 3305, 3542, 3872], 'yet': [3154], 'experienced': [3155], '(cause-specific': [3158], '[aHR]': [3161], '0.004).': [3171], 'models,': [3174], 'neither': [3175], '(aHR': [3178, 3191, 3226, 3239, 3250], '4.56,': [3183], '0.14),': [3186], 'nor': [3187], '1.32,': [3192], '0.69': [3194], '2.50,': [3196], '0.39)': [3199], 'recovery.': [3207, 4366, 4538, 5154], '0.55,': [3227], '0.28': [3229], '1.08,': [3231], '0.08).': [3234], '1.14,': [3240], '0.65': [3242], '1.98,': [3244], '0.65)': [3247], '1.57,': [3251], '0.78': [3253], '3.17,': [3255], '0.21)': [3258], 'covariates,': [3275], 'older': [3281], 'sex': [3299, 5107], 'recovery.Table': [3307], '2Multivariable': [3308], 'cox': [3309], 'models': [3311, 3799, 4493, 4510], 'risks,': [3324], 'inpatientsSevere': [3327], 'Outcome': [3328], '90)Recovery': [3331], '78)HR95%CIp': [3334], 'valueHR95%CIp': [3335], 'valueMen1.200.76-1.890.430.650.40-1.070.09Age': [3336], '(per': [3337], 'years)0.980.86-1.130.790.730.63-0.86<0.001Hypertension1.120.68-1.850.670.980.56-1.730.94CVD1.110.59-2.080.740.700.35-1.400.31CKD0.790.42-1.500.470.860.38-1.900.70Diabetes1.840.94-3.610.070.780.34-1.800.56Obesity1.310.81-2.110.270.700.42-1.170.18Statins0.550.28-1.080.082.691.36-5.330.004ACE': [3339], 'inhibitors1.140.65-1.980.651.320.69-2.500.39ARBs1.570.78-3.170.211.920.81-4.560.14ACEi': [3340], 'cause-specific': [3366, 3401], 'hazard': [3367, 3402], 'ratio.': [3368, 3403], 'ACEi': [3375], 'modeled': [3416], 'separately': [3417], 'shown': [3419, 3898], 'Tables': [3422], '3a-c.': [3423], 'again': [3427], '0.002).': [3434], 'demonstrated': [3436], 'trend': [3438], 'towards': [3439], '0.06),': [3444], '0.78).': [3454], 'sizes': [3456, 5338], 'overall': [3458, 3557], 'series': [3466], '50%': [3489], 'after': [3497, 5665], 'controlling': [3498], 'concomitant': [3505], 'ARBs.': [3511, 4522], 'time-to-event': [3516, 4338, 5422], 'strong': [3520], 'considerably': [3528], 'recovery;': [3532], 'These': [3548], 'timing': [3551], 'combine': [3552], 'account': [3554, 5427], 'occurrence': [3561], 'only': [3582], 'biologic': [3596], 'plausibility': [3597], 'known': [3607, 5802], 'immunomodulator': [3610], 'upregulation': [3616, 4074], 'virus.10Castiglione': [3624], 'Scholar,14Tikoo': [3650], 'Patel': [3652], 'Kumar': [3654], 'Karpe': [3656], 'PA': [3657], 'Sanghavi': [3658], 'Malek': [3660], 'Srinivasan': [3662], 'Tissue': [3664], 'specific': [3665], 'up': [3666], 'regulation': [3667], 'rabbit': [3671], 'atherosclerosis': [3674], 'atorvastatin:': [3676], 'epigenetic': [3679], 'histone': [3680], 'modifications.Biochem': [3681], 'Pharmacol.': [3682], '2015;': [3683, 3879], '93:': [3684], '343-351Crossref': [3685], '(135)': [3688], 'inhibit': [3693], 'protease,': [3704], 'key': [3706], 'enzyme.11Reiner': [3708], 'Coronaviruses': [3748], 'can': [3749, 3805, 5556], 'induce': [3750], 'inflammatory': [3752], 'cascade': [3753], 'toll': [3758, 3813], 'like': [3759, 3814], '4': [3761, 3816], 'myeloid': [3762, 3821], 'differentiation': [3763, 3822], 'protein': [3765, 3824, 3911], '88-nuclear': [3766], 'factor': [3767, 5063, 5136], 'kappa': [3768], 'pathway.10Castiglione': [3770], 'murine': [3798], 'under': [3800], 'periods': [3801], 'stress,': [3803], 'disrupt': [3806], 'pro-inflammatory': [3808], 'stabilization': [3819], 'levels.15Yuan': [3827], 'X': [3828, 3832, 4758, 4762, 4768, 4774, 4817, 4833, 4847, 4877, 4881, 4883, 4887, 4948, 4958, 5083, 5241], 'Deng': [3829, 3933, 4020], 'Shang': [3833], 'Zhu': [3835, 4844], 'Atorvastatin': [3839], 'attenuates': [3840], 'myocardial': [3841], 'remodeling': [3842], 'induced': [3843], 'intermittent': [3846], 'hypoxia': [3847], 'rats:': [3849], 'partly': [3850], 'involvement': [3851], 'TLR-4/MYD88': [3853], 'pathway.Biochem': [3854], 'Biophys': [3855], 'Res': [3856], 'Commun.': [3857], '2014;': [3858], '446:': [3859], '292-297Crossref': [3860], '(57)': [3863], 'Scholar,16Yuan': [3865], 'S.': [3866], 'decrease': [3869], 'fatality': [3871, 5089], 'Middle': [3874], 'East': [3875], 'Respiratory': [3876], 'Syndrome': [3877], 'infection.mBio.': [3878], 'e01120Crossref': [3881], '(74)': [3884], 'SARS-CoV': [3888], 'viruses': [3889], 'employ': [3890], 'cell': [3893], 'entry,': [3894], 'vivo': [3900], 'reduce': [3902], 'upon': [3905], 'viral': [3909], 'spike': [3910], 'receptor.17Kuba': [3915], 'Imai': [3917, 4004], 'Rao': [3919, 4006], 'Gao': [3921, 4008], 'Guan': [3925, 4012], 'Huan': [3927, 4014], 'Bao': [3935, 4022], 'Zheng': [3947, 4034], 'Leibbrandt': [3949, 4036], 'Wada': [3951, 4038], 'Slutsky': [3953, 4040], 'Qin': [3957, 4044, 4735, 4814], 'Penninger': [3961, 4048], 'JM': [3962, 4049, 5233], 'crucial': [3964, 4051], '(ACE2)': [3971, 4058], 'SARS': [3973, 4060], 'coronavirus-induced': [3974, 4061], 'injury.Nat': [3976, 4063], '11:': [3979, 4066], '875-879Crossref': [3980, 4067], '(2546)': [3983, 4070], 'downregulation': [3987], 'leads': [3988], 'excessive': [3990], 'production': [3991], 'angiotensin,': [3993], 'causally': [3997], 'linked': [3998], 'failure.17Kuba': [4002], 'Therefore,': [4073], 'another': [4078], 'mechanism': [4080], 'whereby': [4081], '(as': [4083], 'ARBs)': [4089], 'might': [4090], 'protect': [4091], 'against': [4092], 'injury.8Gurwitz': [4095], 'studies,': [4116], 'influenza-related': [4122], 'hospitalizations,10Castiglione': [4123], 'Scholar,18Vandermeer': [4149], 'ML': [4150], 'Thomas': [4151], 'AR': [4152], 'Kamimoto': [4153], 'Reingold': [4155], 'Gershman': [4157], 'Meek': [4159], 'Farley': [4161], 'MM': [4162, 4827], 'Ryan': [4163], 'Lynfield': [4165], 'Baumbach': [4167], 'Schaffner': [4169], 'Bennett': [4171], 'Zansky': [4173], 'laboratory-confirmed': [4186], 'influenza': [4187, 4240], 'virus': [4188], 'infections:': [4189], 'multistate': [4191], 'study.J': [4192], 'Infect': [4193], 'Dis.': [4194], '2012;': [4195], '205:': [4196], '13-19Crossref': [4197], '(176)': [4200], '19Brett': [4203], 'SJ': [4204], 'Myles': [4205], 'Lim': [4207], 'WS': [4208], 'Enstone': [4209], 'JE': [4210], 'Bannister': [4211], 'Semple': [4213], 'MG': [4214], 'Read': [4215], 'RC': [4216], 'Taylor': [4217], 'McMenamin': [4219], 'Nicholson': [4221], 'KG': [4222], 'Nguyen-Van-Tam': [4223], 'JS': [4224, 4639, 4653], 'Openshaw': [4225], 'PJ': [4226], 'Influenza': [4227, 4260], 'Information': [4229], 'N.': [4230], 'Pre-admission': [4231], 'in-hospital': [4235, 5444], '2009': [4238], 'pandemic': [4239], 'A(H1N1)': [4241], 'disease.PLoS': [4242], 'One.': [4243], '2011;': [4244], 'e18120Crossref': [4246], '(47)': [4249], '20Frost': [4252], 'Petersen': [4254], 'Tollestrup': [4256], 'Skipper': [4258], 'protection': [4264], 'pleiotropic,': [4266], 'dose-dependent': [4267], 'statins.Chest.': [4270], '131:': [4272], '1006-1012Abstract': [4273], '(251)': [4281], 'improved': [4286], 'community': [4289], 'acquired': [4290], 'pneumonia': [4291], 'sepsis.21Pertzov': [4293], 'Eliakim-Raz': [4295], 'Atamna': [4297], 'Trestioreanu': [4299], 'AZ': [4300], 'Yahav': [4301], 'Leibovici': [4303], 'Hydroxymethylglutaryl-CoA': [4305], 'reductase': [4306], '(statins)': [4308], 'sepsis': [4313], 'adults': [4315], 'meta-analysis.Clin': [4321], 'Microbiol': [4322], '2019;': [4324], '25:': [4325], '280-289Abstract': [4326], '(33)': [4334], 'alone': [4342], 'entered': [4377], 'jointly': [4378], 'attenuated,': [4392], 'retained': [4396], 'robust': [4398, 4718], 'effect.': [4399], 'percentage': [4403], 'medications,': [4408], 'plausible': [4411], 'major': [4414], 'portion': [4415], 'observed': [4418], 'fact': [4425], 'attributable': [4426], 'On': [4429], 'hand,': [4432], 'regressions': [4436], 'seen': [4446], 'cohorts.22Lipsitch': [4452], 'Tchetgen': [4454, 4455, 5611, 5612], 'E': [4456, 4631, 5239, 5613], 'Cohen': [4457, 5614], 'Negative': [4459, 5616], 'controls:': [4460, 5617], 'tool': [4462, 5619], 'detecting': [4464, 5621], 'bias': [4467, 5554, 5624], 'studies.Epidemiology.': [4470, 5627], '2010;': [4471, 5628], '21:': [4472, 5629], '383-388Crossref': [4473, 5630], '(739)': [4476, 5633], 'comparison': [4480], 'controls': [4483], 'suggests': [4484], 'any': [4486], 'residual': [4487, 5281, 5309], 'biased': [4495], 'toward': [4496], 'whereas': [4502], 'found': [4504, 4543], 'beneficial': [4507, 4519, 4713, 5298], 'lending': [4515], 'contrast,': [4524], 'predictive': [4530], 'Previous': [4539], 'studies': [4541, 4702], 'COVID-19.9Mehta': [4561], 'Scholar,23Reynolds': [4622], 'Adhikari': [4624], 'Pulgarin': [4626], 'Troxel': [4628], 'AB': [4629], 'Iturrate': [4630], 'Johnson': [4632], 'SB': [4633], 'Hausvater': [4634], 'Newman': [4636], 'Berger': [4638], 'Bangalore': [4640], 'Katz': [4642], 'SD': [4643], 'Fishman': [4644], 'GI': [4645], 'Kunichoff': [4646], 'Chen': [4648, 4826, 4852, 4945, 5082], 'Ogedegbe': [4650], 'Hochman': [4652], 'Renin-angiotensin-aldosterone': [4654, 4681], 'covid-19.N': [4660, 4688], 'Engl': [4661, 4689], '382:': [4665, 4693], '2441-2448Crossref': [4666], '(813)': [4669], 'Scholar,24Mancia': [4671], 'Rea': [4673], 'Ludergnani': [4675], 'Apolone': [4677], 'Corrao': [4679], '2431-2440Crossref': [4694], '(815)': [4697], 'Some': [4700], 'inpatient': [4704], 'suggested': [4710], 'possible': [4712], 'effect,': [4714], 'appears': [4716], 'inhibitors.25Zhou': [4723], 'YM': [4726], 'Xie': [4727], 'Lei': [4731, 4824], 'Cai': [4737, 4904], 'XJ': [4740, 4813], 'Xia': [4743, 4757, 4783, 4836, 4876, 4900], 'Xiang': [4745], 'Ma': [4749, 4846], 'XL': [4750], 'Lu': [4753, 4755, 4862, 4874, 4959], 'Liao': [4761, 4880], 'Huang': [4767], 'BH': [4770, 4885], 'Yuan': [4771, 4822], 'Wei': [4773, 4882], 'PP': [4776, 4895], 'She': [4781, 4842], 'ZG': [4782, 4843], 'Comparative': [4787], 'impacts': [4788], 'versus': [4794], 'mortality.Hypertension.': [4804], '76': [4806], '(e15–7)Crossref': [4807], '26Zhang': [4812], 'Cheng': [4816], 'Shen': [4818], 'YC': [4821], 'Bai': [4830], 'Lin': [4834], 'Mao': [4856], 'Yan': [4858], 'Xiao': [4860], 'GN': [4891], 'Loomba': [4896], 'Ji': [4898], 'YX': [4899], 'In-hospital': [4910], 'COVID-19.Cell': [4925], 'Metab.': [4926], '32': [4928], '(e174):': [4929], '176-187Abstract': [4930], '(337)': [4938], '27Guo': [4941], 'Fan': [4943], 'He': [4951], 'Wan': [4955], 'Cardiovascular': [4961], 'implications': [4962], 'fatal': [4964], '5:': [4975], '1-8Crossref': [4976], '(2703)': [4978], 'Ongoing': [4981], 'trials': [4983, 5679], 'evaluating': [4985], 'speed': [4992], 'improve': [4995, 5688], 'outcomes.': [4996], 'Our': [4997, 5438], 'findings': [4998], 'consistent': [5012, 5112], 'reports.1Ruan': [5015], 'Scholar,28Sattar': [5053], 'McInnes': [5055], 'IB': [5056], 'McMurray': [5057], 'JJV': [5058], 'infection:': [5067], 'mechanisms.Circulation.': [5070], '142:': [5072], '4-6Crossref': [5073], '(473)': [5076], 'Scholar,29Deng': [5078], 'Yin': [5080], 'Zeng': [5084], 'determinants': [5087], '44,672': [5091], 'COVID-19.Crit': [5094], 'Care.': [5095], '24:': [5097], '179Crossref': [5098], '(165)': [5101], 'consistently': [5108], 'estimated': [5110], 'risk.': [5115], 'novel': [5141], 'finding': [5142, 5214], 'younger': [5145, 5169], 'reflect': [5157], 'resilient': [5160], 'though': [5162], 'presenting': [5171], 'later': [5172], 'course': [5176], 'current': [5180, 5205], 'smoking': [5181, 5199], 'prevalent': [5184], 'opposed': [5190], 'very': [5195], 'low': [5196], '(only': [5203], '8': [5204], 'smokers': [5206], 'identified)': [5208], 'makes': [5209], 'validity': [5211], 'questionable.': [5215], 'Given': [5216], 'nicotine': [5220], 'play': [5222], 'pathway,': [5228], 'further': [5229], 'investigation': [5230], 'warranted.30Oakes': [5232], 'Fuchs': [5234], 'RM': [5235], 'Gardner': [5236], 'Lazartigues': [5238], 'Yue': [5240], 'Nicotine': [5242], 'renin-angiotensin': [5245], 'system.Am': [5246], 'Physiol': [5248], 'Regul': [5249], 'Integr': [5250], 'Comp': [5251], 'Physiol.': [5252], '2018;': [5253], '315:': [5254], 'R895-R906Crossref': [5255], '(194)': [5258], 'Limitations': [5261], 'include': [5266], 'its': [5267], 'design': [5269, 5501], 'cannot': [5271, 5307], 'prove': [5272], 'causality': [5273], 'leaves': [5276], 'open': [5277], 'confounding,': [5282], 'relatively': [5285], 'small': [5286], 'size.': [5288], 'exclude': [5308], 'contributing': [5313], 'factor;': [5314], 'however': [5315, 5370], 'size': [5318], 'much': [5323], 'larger': [5324], '-negative': [5343], 'cohorts.': [5344], 'would': [5348, 5521], 'expected': [5350], 'affect': [5352], 'favorably': [5355], 'non-COVID-19': [5357], 'heterogeneous': [5364], 'group': [5365], 'limitation,': [5369], 'strength': [5375], 'allows': [5379], 'us': [5380, 5603], 'control': [5382, 5590], 'biases': [5385], 'present.': [5390], 'extensive': [5392], 'manual': [5393, 5547], 'chart': [5394, 5548], 'performed,': [5397], 'remains': [5399], 'possibility.': [5401], '(or': [5407], 'earlier)': [5415], 'beginning': [5418], 'our': [5421], 'does': [5425], 'variation': [5429], 'duration': [5432, 5479], 'did': [5440, 5471], 'evaluate': [5442], 'should': [5455], 'extrapolated': [5458], 'reliable': [5474], 'dose': [5477], 'use;': [5482], 'time-dependent.': [5495], 'Similarly,': [5496], 'assess': [5506, 5605, 5683], 'infection,': [5519], 'require': [5522], 'widespread,': [5523], 'asymptomatic': [5527], 'individuals.': [5528], 'many': [5533], 'strengths.': [5534], 'By': [5535], 'restricting': [5536], 'documented': [5542], 'careful': [5546], 'review,': [5549], 'eliminated': [5551], 'occur': [5557], 'most': [5560], 'ill': [5561], 'who,': [5563], 'since': [5564], 'intubated': [5565], 'often': [5567, 5572], 'transferred': [5568], 'outside': [5570], 'facilities,': [5571], 'incomplete': [5574], 'documentation': [5575], 'able': [5584], 'leverage': [5586], 'period,': [5600], 'enabled': [5602], 'bias.22Lipsitch': [5609], 'summary,': [5637], 'demographics': [5668], 'study.': [5676], 'Randomized': [5677], 'underway': [5681], 'Lori': [5693], 'B.': [5694], 'Daniels:': [5695], 'Conceptualization,': [5696, 5743, 5773, 5782], 'Methodology,': [5697, 5774, 5783], 'Validation,': [5698], 'Formal': [5699, 5732, 5736, 5749, 5784], 'Analysis,': [5700, 5750, 5785], 'Investigation,': [5701], 'Resources,': [5702, 5762], 'Curation,': [5704, 5724], 'Writing': [5705, 5709, 5725, 5741, 5751, 5760, 5775, 5786, 5790], '–': [5706, 5710, 5726, 5742, 5752, 5761, 5776, 5787, 5791], 'Original': [5707, 5788], 'Draft,': [5708, 5789], 'Editing,': [5713, 5755, 5765], 'Visualization,': [5714], 'Supervision,': [5715], 'Project': [5716, 5766], 'Administration,': [5717, 5767], 'Funding': [5718, 5768], 'Acquisition;': [5719, 5769], 'Amy': [5720], 'M.': [5721, 5739], 'Sitapati:': [5722], 'Editing;': [5729, 5746, 5779], 'Jing': [5730], 'Zhang:': [5731], 'Analysisl;': [5733], 'Jingjing': [5734], 'Zou:': [5735], 'Analysis;': [5737], 'Quan': [5738], 'Bui:': [5740], 'Junting': [5747], 'Ren:': [5748], 'Visualization;': [5756], 'Christopher': [5757], 'A.': [5758], 'Longhurst:': [5759], 'Michael': [5770], 'H.': [5771], 'Criqui:': [5772], 'Karen': [5780], 'Messer:': [5781], 'Editing.': [5794], 'authors': [5796], 'declare': [5797], 'financial': [5804], 'interests': [5805], 'personal': [5807], 'relationships': [5808], 'appeared': [5812], 'work': [5816], 'paper.': [5820], 'Download': [5821, 5843, 5851, 5859], '.jpg': [5822], '(.46': [5823], 'MB)': [5824, 5846, 5854, 5862], 'Help': [5825, 5847, 5855, 5863], 'files': [5827, 5850, 5858, 5866], 'Predictors': [5831], '.docx': [5844, 5852, 5860], '(.01': [5845, 5853], 'docx': [5849, 5857, 5865], '(.02': [5861]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3086446357', 'counts_by_year': [{'year': 2024, 'cited_by_count': 13}, {'year': 2023, 'cited_by_count': 21}, {'year': 2022, 'cited_by_count': 32}, {'year': 2021, 'cited_by_count': 81}, {'year': 2020, 'cited_by_count': 15}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2025-01-03T00:52:19.997713', 'created_date': '2020-09-21'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
