Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3084039995', 'doi': 'https://doi.org/10.1186/s12859-020-03731-y', 'title': 'Automated classification of protein subcellular localization in immunohistochemistry images to reveal biomarkers in colon cancer', 'display_name': 'Automated classification of protein subcellular localization in immunohistochemistry images to reveal biomarkers in colon cancer', 'publication_year': 2020, 'publication_date': '2020-09-09', 'ids': {'openalex': 'https://openalex.org/W3084039995', 'doi': 'https://doi.org/10.1186/s12859-020-03731-y', 'mag': '3084039995', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32907537', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7487883'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-020-03731-y', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03731-y', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03731-y', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080527274', 'display_name': 'Zhen‐Zhen Xue', 'orcid': 'https://orcid.org/0000-0001-8183-088X'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhen-Zhen Xue', 'raw_affiliation_strings': ['School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, China'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, China', 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101834900', 'display_name': 'Yanxia Wu', 'orcid': 'https://orcid.org/0009-0006-2226-5757'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yanxia Wu', 'raw_affiliation_strings': ['Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China', 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019652201', 'display_name': 'Qingzu Gao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210115182', 'display_name': 'First Affiliated Hospital of Xinxiang Medical University', 'ror': 'https://ror.org/0278r4c85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210115182']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qing-Zu Gao', 'raw_affiliation_strings': ['The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China', 'institution_ids': ['https://openalex.org/I4210115182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101780128', 'display_name': 'Liang Zhao', 'orcid': 'https://orcid.org/0000-0002-1429-0884'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Liang Zhao', 'raw_affiliation_strings': ['Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China', 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063096622', 'display_name': 'Ying‐Ying Xu', 'orcid': 'https://orcid.org/0000-0002-3185-811X'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ying-Ying Xu', 'raw_affiliation_strings': ['School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, China'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, China', 'institution_ids': ['https://openalex.org/I58200834']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1690, 'currency': 'GBP', 'value_usd': 2072, 'provenance': 'doaj'}, 'apc_paid': {'value': 1690, 'currency': 'GBP', 'value_usd': 2072, 'provenance': 'doaj'}, 'fwci': 1.459, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.999982, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '21', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12254', 'display_name': 'Prediction of Protein Subcellular Localization', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12254', 'display_name': 'Prediction of Protein Subcellular Localization', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10015', 'display_name': 'RNA Sequencing Data Analysis', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12576', 'display_name': 'Prediction of Peptide-MHC Binding Affinity', 'score': 0.9886, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/human-protein-atlas', 'display_name': 'Human Protein Atlas', 'score': 0.81868017}, {'id': 'https://openalex.org/keywords/subcellular-localization', 'display_name': 'Subcellular Localization', 'score': 0.630838}, {'id': 'https://openalex.org/keywords/biomarker-discovery', 'display_name': 'Biomarker discovery', 'score': 0.59806806}, {'id': 'https://openalex.org/keywords/tissue-microarray', 'display_name': 'Tissue microarray', 'score': 0.44506007}, {'id': 'https://openalex.org/keywords/cancer-biomarkers', 'display_name': 'Cancer biomarkers', 'score': 0.41877353}], 'concepts': [{'id': 'https://openalex.org/C2776879804', 'wikidata': 'https://www.wikidata.org/wiki/Q7630919', 'display_name': 'Subcellular localization', 'level': 3, 'score': 0.89766043}, {'id': 'https://openalex.org/C158163496', 'wikidata': 'https://www.wikidata.org/wiki/Q5937310', 'display_name': 'Human Protein Atlas', 'level': 4, 'score': 0.81868017}, {'id': 'https://openalex.org/C2781197716', 'wikidata': 'https://www.wikidata.org/wiki/Q864574', 'display_name': 'Biomarker', 'level': 2, 'score': 0.7120666}, {'id': 'https://openalex.org/C124535831', 'wikidata': 'https://www.wikidata.org/wiki/Q4915074', 'display_name': 'Biomarker discovery', 'level': 4, 'score': 0.59806806}, {'id': 'https://openalex.org/C140051345', 'wikidata': 'https://www.wikidata.org/wiki/Q7251501', 'display_name': 'Protein subcellular localization prediction', 'level': 3, 'score': 0.5674191}, {'id': 'https://openalex.org/C46111723', 'wikidata': 'https://www.wikidata.org/wiki/Q471857', 'display_name': 'Proteomics', 'level': 3, 'score': 0.5287264}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.48585293}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.47858405}, {'id': 'https://openalex.org/C193270364', 'wikidata': 'https://www.wikidata.org/wiki/Q17141925', 'display_name': 'Tissue microarray', 'level': 3, 'score': 0.44506007}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.439878}, {'id': 'https://openalex.org/C2777002142', 'wikidata': 'https://www.wikidata.org/wiki/Q5031432', 'display_name': 'Cancer biomarkers', 'level': 3, 'score': 0.41877353}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.41085163}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39730453}, {'id': 'https://openalex.org/C154945302', 'wikidata': 'https://www.wikidata.org/wiki/Q11660', 'display_name': 'Artificial intelligence', 'level': 1, 'score': 0.39681208}, {'id': 'https://openalex.org/C153180895', 'wikidata': 'https://www.wikidata.org/wiki/Q7148389', 'display_name': 'Pattern recognition (psychology)', 'level': 2, 'score': 0.36034948}, {'id': 'https://openalex.org/C6856738', 'wikidata': 'https://www.wikidata.org/wiki/Q331672', 'display_name': 'Protein expression', 'level': 3, 'score': 0.20483667}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.20142269}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.093592376}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.07317647}], 'mesh': [{'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003110', 'descriptor_name': 'Colonic Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003110', 'descriptor_name': 'Colonic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003110', 'descriptor_name': 'Colonic Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D030562', 'descriptor_name': 'Databases, Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000069550', 'descriptor_name': 'Machine Learning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000145', 'qualifier_name': 'classification', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-020-03731-y', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03731-y', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/244c51764bb84e18ac86f76828774e1e', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487883', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/32907537', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-020-03731-y', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-020-03731-y', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.44}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '61803196'}, {'funder': 'https://openalex.org/F4320321921', 'funder_display_name': 'Natural Science Foundation of Guangdong Province', 'award_id': '2018030310282'}], 'datasets': ['https://openalex.org/W4394081148'], 'versions': [], 'referenced_works_count': 42, 'referenced_works': ['https://openalex.org/W1943620659', 'https://openalex.org/W1987206765', 'https://openalex.org/W2012758140', 'https://openalex.org/W2070852189', 'https://openalex.org/W2090894302', 'https://openalex.org/W2097117768', 'https://openalex.org/W2108598243', 'https://openalex.org/W2108835658', 'https://openalex.org/W2116633773', 'https://openalex.org/W2118765266', 'https://openalex.org/W2150363947', 'https://openalex.org/W2152482858', 'https://openalex.org/W2153349010', 'https://openalex.org/W2153635508', 'https://openalex.org/W2154477800', 'https://openalex.org/W2156691430', 'https://openalex.org/W2165698076', 'https://openalex.org/W2183341477', 'https://openalex.org/W2194775991', 'https://openalex.org/W2263523065', 'https://openalex.org/W2469738399', 'https://openalex.org/W2566825588', 'https://openalex.org/W2606209624', 'https://openalex.org/W2608745162', 'https://openalex.org/W2616487990', 'https://openalex.org/W2805367049', 'https://openalex.org/W2886555678', 'https://openalex.org/W2900490197', 'https://openalex.org/W2906946803', 'https://openalex.org/W2908360938', 'https://openalex.org/W2910124299', 'https://openalex.org/W2930484514', 'https://openalex.org/W2946026608', 'https://openalex.org/W2949648625', 'https://openalex.org/W2950695830', 'https://openalex.org/W2963446712', 'https://openalex.org/W2972737141', 'https://openalex.org/W2982028254', 'https://openalex.org/W2991083105', 'https://openalex.org/W2995455303', 'https://openalex.org/W4236965008', 'https://openalex.org/W4246105018'], 'related_works': ['https://openalex.org/W4313340440', 'https://openalex.org/W4205775722', 'https://openalex.org/W2991044112', 'https://openalex.org/W2726477821', 'https://openalex.org/W2613629789', 'https://openalex.org/W2351398203', 'https://openalex.org/W2306419033', 'https://openalex.org/W2135565251', 'https://openalex.org/W2065906032', 'https://openalex.org/W2012210483'], 'abstract_inverted_index': {'Protein': [0], 'biomarkers': [1, 119, 176], 'play': [2], 'important': [3], 'roles': [4], 'in': [5, 18, 108, 189], 'cancer': [6, 23, 118], 'diagnosis.': [7], 'Many': [8], 'efforts': [9], 'have': [10], 'been': [11, 45], 'made': [12], 'on': [13, 62, 178], 'measuring': [14], 'abnormal': [15], 'expression': [16], 'intensity': [17], 'biological': [19], 'samples': [20], 'to': [21, 56, 76, 85, 147, 186], 'identity': [22], 'types': [24], 'and': [25, 41, 69, 96, 100, 124, 138, 156, 159, 170, 196], 'stages.': [26], 'However,': [27], 'the': [28, 71, 74, 125, 141, 164], 'change': [29, 148], 'of': [30, 33, 65, 73, 81, 110, 116, 140, 166], 'subcellular': [31, 59, 78, 168, 180, 192], 'location': [32, 79, 200], 'proteins,': [34], 'which': [35], 'is': [36, 184], 'also': [37], 'critical': [38], 'for': [39, 194], 'understanding': [40], 'detecting': [42], 'diseases,': [43], 'has': [44], 'rarely': [46], 'studied.In': [47], 'this': [48], 'work,': [49], 'we': [50], 'developed': [51], 'a': [52], 'machine': [53], 'learning': [54, 102], 'model': [55, 75, 89, 172], 'classify': [57], 'protein': [58, 127, 167, 179], 'locations': [60], 'based': [61, 177], 'immunohistochemistry': [63], 'images': [64], 'human': [66, 126], 'colon': [67, 86, 117], 'tissues,': [68], 'validated': [70], 'ability': [72], 'detect': [77, 175], 'changes': [80], 'biomarker': [82, 142], 'proteins': [83, 143, 195], 'related': [84], 'cancer.': [87], 'The': [88], 'uses': [90], 'representative': [91], 'image': [92, 154], 'patches': [93, 155], 'as': [94], 'inputs,': [95], 'integrates': [97], 'feature': [98], 'engineering': [99], 'deep': [101, 160], 'methods.': [103], 'It': [104, 133], 'achieves': [105], '92.69%': [106], 'accuracy': [107], 'classification': [109], 'new': [111, 198], 'proteins.': [112], 'Two': [113], 'validation': [114], 'datasets': [115], 'derived': [120], 'from': [121], 'published': [122], 'literatures': [123], 'atlas': [128], 'database': [129], 'respectively': [130], 'are': [131], 'employed.': [132], 'turns': [134], 'out': [135], 'that': [136, 152], '81.82': [137], '65.66%': [139], 'can': [144, 162, 173], 'be': [145, 187], 'identified': [146], 'locations.Our': [149], 'results': [150], 'demonstrate': [151], 'using': [153], 'combining': [157], 'predefined': [158], 'features': [161], 'improve': [163], 'performance': [165], 'localization,': [169], 'our': [171], 'effectively': [174], 'translocations.': [181], 'This': [182], 'study': [183], 'anticipated': [185], 'useful': [188], 'annotating': [190], 'unknown': [191], 'localization': [193], 'discovering': [197], 'potential': [199], 'biomarkers.': [201]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3084039995', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}], 'updated_date': '2024-09-14T17:18:16.474248', 'created_date': '2020-09-14'}