Title: Anti‐obesity potentiality of Tapra fish ( <i>Opisthopterus tardoore</i> ) oil
Abstract: Journal of Food BiochemistryVolume 44, Issue 11 e13448 FULL ARTICLE Anti-obesity potentiality of Tapra fish (Opisthopterus tardoore) oil Shrabani Pradhan, Shrabani Pradhan Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorTitli Panchali, Titli Panchali Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorBani Paul, Bani Paul Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorAmina Khatun, Amina Khatun Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorSreenivasa Rao Jarapala, Sreenivasa Rao Jarapala Food Chemistry and Nutrient Analysis, National Institute of Nutrition (ICMR), Hyderabad, IndiaSearch for more papers by this authorKeshab Chandra Mondal, Keshab Chandra Mondal Department of Microbiology, Vidyasagar University, Midnapore, IndiaSearch for more papers by this authorKuntal Ghosh PhD, Corresponding Author Kuntal Ghosh PhD [email protected] Department of Biological Sciences, Midnapore City College, Midnapore, India Correspondence Sudipta Chakrabarti and Kuntal Ghosh, Department of Biological Sciences, Midnapore City College, Midnapore, West Bengal, India. Email: [email protected] (S. C.) and [email protected] (K. G.)Search for more papers by this authorSudipta Chakrabarti PhD, Corresponding Author Sudipta Chakrabarti PhD [email protected] orcid.org/0000-0002-4867-160X Department of Biological Sciences, Midnapore City College, Midnapore, India Correspondence Sudipta Chakrabarti and Kuntal Ghosh, Department of Biological Sciences, Midnapore City College, Midnapore, West Bengal, India. Email: [email protected] (S. C.) and [email protected] (K. G.)Search for more papers by this author Shrabani Pradhan, Shrabani Pradhan Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorTitli Panchali, Titli Panchali Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorBani Paul, Bani Paul Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorAmina Khatun, Amina Khatun Department of Biological Sciences, Midnapore City College, Midnapore, IndiaSearch for more papers by this authorSreenivasa Rao Jarapala, Sreenivasa Rao Jarapala Food Chemistry and Nutrient Analysis, National Institute of Nutrition (ICMR), Hyderabad, IndiaSearch for more papers by this authorKeshab Chandra Mondal, Keshab Chandra Mondal Department of Microbiology, Vidyasagar University, Midnapore, IndiaSearch for more papers by this authorKuntal Ghosh PhD, Corresponding Author Kuntal Ghosh PhD [email protected] Department of Biological Sciences, Midnapore City College, Midnapore, India Correspondence Sudipta Chakrabarti and Kuntal Ghosh, Department of Biological Sciences, Midnapore City College, Midnapore, West Bengal, India. Email: [email protected] (S. C.) and [email protected] (K. G.)Search for more papers by this authorSudipta Chakrabarti PhD, Corresponding Author Sudipta Chakrabarti PhD [email protected] orcid.org/0000-0002-4867-160X Department of Biological Sciences, Midnapore City College, Midnapore, India Correspondence Sudipta Chakrabarti and Kuntal Ghosh, Department of Biological Sciences, Midnapore City College, Midnapore, West Bengal, India. Email: [email protected] (S. C.) and [email protected] (K. G.)Search for more papers by this author First published: 03 September 2020 https://doi.org/10.1111/jfbc.13448Citations: 3 Funding information The authors are grateful for the financial assistance from the Indian Council of Medical Research (ICMR), Govt. of India (Sanction No. 5/9/1223/2019-Nut. dated July 23, 2019). Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract In this present investigation, we have extracted and characterized the Tapra fish oil as well as applied it to evaluate anti-obesity potentiality. The Tapra fish oil had 1.14 ± 0.10 mg KOH/g of acid value, 129.8 ± 5.09 mg KOH/g of saponification number, 2.67 ± 0.67 mEq/kg of peroxide value, 121.9 ± 2.14 mg of iodine value, and 17.67 ± 1.45 totox value. Gas Chromatography-Mass Spectrometric analysis clearly revealed the presence of nine different fatty acids. When the fish oil was applied to high-fat diet-induced obese mice, it showed significant reduction of body weight, Body Mass Index, and serum lipid profiles compared to the high-fat diet-induced obese mice. The levels of leptin and TNF-α were moderately reduced in fish oil treated high-fat diet-induced obese mice than control obese mice. In conclusion, the Tapra fish oil was enriched with essential fatty acids and it could be used as an antiobese food supplement. Practical applications Considering the adverse effects of drugs used for the treatment of obesity, there is always a need to find out the alternatives. While the anti-obesity potentialities of different sea fish oil have been documented, the same for the Tapra fish (Opisthopterus tardoore) oil has not been studied at all. The extracted Tapra fish oil was found good in quality. Administration of fish oil in the mice exhibited anti-obesity effect in terms of lowering body weight, Body Mass Index, and serum lipid profiles, leptin, and TNF-α in mice model. These findings are fostering new therapeutic approaches to obesity treatment. CONFLICT OF INTEREST The authors declare no potential conflict of interest. Citing Literature Supporting Information Filename Description jfbc13448-sup-0001-FigS1.docxWord document, 43.2 KB Fig S1 Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume44, Issue11November 2020e13448 RelatedInformation