Publication Information

{'id': 'https://openalex.org/W3080884461', 'doi': 'https://doi.org/10.1093/cid/ciaa1204', 'title': 'A Randomized Phase 2 Study of VT-1161 for the Treatment of Acute Vulvovaginal Candidiasis', 'display_name': 'A Randomized Phase 2 Study of VT-1161 for the Treatment of Acute Vulvovaginal Candidiasis', 'publication_year': 2020, 'publication_date': '2020-08-13', 'ids': {'openalex': 'https://openalex.org/W3080884461', 'doi': 'https://doi.org/10.1093/cid/ciaa1204', 'mag': '3080884461', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32818963', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8492116'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/cid/ciaa1204', 'pdf_url': 'https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa1204/33890841/ciaa1204.pdf', 'source': {'id': 'https://openalex.org/S72350973', 'display_name': 'Clinical Infectious Diseases', 'issn_l': '1058-4838', 'issn': ['1058-4838', '1537-6591'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa1204/33890841/ciaa1204.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5041510712', 'display_name': 'Stephen Brand', 'orcid': 'https://orcid.org/0000-0002-1796-5584'}, 'institutions': [{'id': 'https://openalex.org/I4210151457', 'display_name': 'Viamet Pharmaceuticals (United States)', 'ror': 'https://ror.org/0511egv62', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210151457']}, {'id': 'https://openalex.org/I4210161705', 'display_name': 'Mycovia Pharmaceuticals (United States)', 'ror': 'https://ror.org/04j9kzt69', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210161705']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Stephen R Brand', 'raw_affiliation_strings': ['Mycovia Pharmaceuticals, Durham, North Carolina, USA', 'Viamet Pharmaceuticals, Durham, North Carolina, USA'], 'affiliations': [{'raw_affiliation_string': 'Viamet Pharmaceuticals, Durham, North Carolina, USA', 'institution_ids': ['https://openalex.org/I4210151457']}, {'raw_affiliation_string': 'Mycovia Pharmaceuticals, Durham, North Carolina, USA', 'institution_ids': ['https://openalex.org/I4210161705']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054286469', 'display_name': 'Jack D. Sobel', 'orcid': 'https://orcid.org/0000-0002-5589-4609'}, 'institutions': [{'id': 'https://openalex.org/I185443292', 'display_name': 'Wayne State University', 'ror': 'https://ror.org/01070mq45', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I185443292']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jack D Sobel', 'raw_affiliation_strings': ['School of Medicine, Wayne State University, Detroit, Michigan, USA'], 'affiliations': [{'raw_affiliation_string': 'School of Medicine, Wayne State University, Detroit, Michigan, USA', 'institution_ids': ['https://openalex.org/I185443292']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022890391', 'display_name': 'Paul Nyirjesy', 'orcid': 'https://orcid.org/0000-0001-5309-2971'}, 'institutions': [{'id': 'https://openalex.org/I149251103', 'display_name': 'Thomas Jefferson University', 'ror': 'https://ror.org/00ysqcn41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I149251103']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Paul Nyirjesy', 'raw_affiliation_strings': ['Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA'], 'affiliations': [{'raw_affiliation_string': 'Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA', 'institution_ids': ['https://openalex.org/I149251103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089635085', 'display_name': 'Mahmoud A. Ghannoum', 'orcid': 'https://orcid.org/0000-0002-8833-7323'}, 'institutions': [{'id': 'https://openalex.org/I2799343972', 'display_name': 'University Hospitals of Cleveland', 'ror': 'https://ror.org/0130jk839', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799343972']}, {'id': 'https://openalex.org/I58956616', 'display_name': 'Case Western Reserve University', 'ror': 'https://ror.org/051fd9666', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I58956616']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mahmoud A Ghannoum', 'raw_affiliation_strings': ['Center for Medical Mycology, Case Western Reserve University, and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA'], 'affiliations': [{'raw_affiliation_string': 'Center for Medical Mycology, Case Western Reserve University, and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA', 'institution_ids': ['https://openalex.org/I2799343972', 'https://openalex.org/I58956616']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073464082', 'display_name': 'Robert J. Schotzinger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151457', 'display_name': 'Viamet Pharmaceuticals (United States)', 'ror': 'https://ror.org/0511egv62', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210151457']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert J Schotzinger', 'raw_affiliation_strings': ['Viamet Pharmaceuticals, Durham, North Carolina, USA'], 'affiliations': [{'raw_affiliation_string': 'Viamet Pharmaceuticals, Durham, North Carolina, USA', 'institution_ids': ['https://openalex.org/I4210151457']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068329483', 'display_name': 'Thorsten P. Degenhardt', 'orcid': 'https://orcid.org/0000-0002-9424-0931'}, 'institutions': [{'id': 'https://openalex.org/I4210151457', 'display_name': 'Viamet Pharmaceuticals (United States)', 'ror': 'https://ror.org/0511egv62', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210151457']}, {'id': 'https://openalex.org/I4210161705', 'display_name': 'Mycovia Pharmaceuticals (United States)', 'ror': 'https://ror.org/04j9kzt69', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210161705']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Thorsten P Degenhardt', 'raw_affiliation_strings': ['Mycovia Pharmaceuticals, Durham, North Carolina, USA', 'Viamet Pharmaceuticals, Durham, North Carolina, USA'], 'affiliations': [{'raw_affiliation_string': 'Viamet Pharmaceuticals, Durham, North Carolina, USA', 'institution_ids': ['https://openalex.org/I4210151457']}, {'raw_affiliation_string': 'Mycovia Pharmaceuticals, Durham, North Carolina, USA', 'institution_ids': ['https://openalex.org/I4210161705']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5041510712'], 'corresponding_institution_ids': ['https://openalex.org/I4210151457', 'https://openalex.org/I4210161705'], 'apc_list': {'value': 4320, 'currency': 'USD', 'value_usd': 4320, 'provenance': 'doaj'}, 'apc_paid': {'value': 4320, 'currency': 'USD', 'value_usd': 4320, 'provenance': 'doaj'}, 'fwci': 1.058, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 49, 'citation_normalized_percentile': {'value': 0.788489, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '73', 'issue': '7', 'first_page': 'e1518', 'last_page': 'e1524'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10150', 'display_name': 'Antifungal resistance and susceptibility', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10150', 'display_name': 'Antifungal resistance and susceptibility', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11037', 'display_name': 'Fungal Infections and Studies', 'score': 0.9913, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11253', 'display_name': 'Nail Diseases and Treatments', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/discontinuation', 'display_name': 'Discontinuation', 'score': 0.76007235}, {'id': 'https://openalex.org/keywords/vulvovaginal-candidiasis', 'display_name': 'Vulvovaginal Candidiasis', 'score': 0.5714378}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9251209}, {'id': 'https://openalex.org/C2780651595', 'wikidata': 'https://www.wikidata.org/wiki/Q411478', 'display_name': 'Fluconazole', 'level': 3, 'score': 0.8877417}, {'id': 'https://openalex.org/C2778715236', 'wikidata': 'https://www.wikidata.org/wiki/Q55622662', 'display_name': 'Discontinuation', 'level': 2, 'score': 0.76007235}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.7335357}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6190535}, {'id': 'https://openalex.org/C2910082039', 'wikidata': 'https://www.wikidata.org/wiki/Q977090', 'display_name': 'Vulvovaginal Candidiasis', 'level': 3, 'score': 0.5714378}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.5062079}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.42715612}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.42133883}, {'id': 'https://openalex.org/C2779548794', 'wikidata': 'https://www.wikidata.org/wiki/Q578726', 'display_name': 'Antifungal', 'level': 2, 'score': 0.21889612}, {'id': 'https://openalex.org/C16005928', 'wikidata': 'https://www.wikidata.org/wiki/Q171171', 'display_name': 'Dermatology', 'level': 1, 'score': 0.17400214}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002181', 'descriptor_name': 'Candidiasis, Vulvovaginal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000284', 'descriptor_name': 'Administration, Oral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000935', 'descriptor_name': 'Antifungal Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000935', 'descriptor_name': 'Antifungal Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002181', 'descriptor_name': 'Candidiasis, Vulvovaginal', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015725', 'descriptor_name': 'Fluconazole', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015725', 'descriptor_name': 'Fluconazole', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011725', 'descriptor_name': 'Pyridines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011725', 'descriptor_name': 'Pyridines', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D013777', 'descriptor_name': 'Tetrazoles', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D013777', 'descriptor_name': 'Tetrazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/cid/ciaa1204', 'pdf_url': 'https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa1204/33890841/ciaa1204.pdf', 'source': {'id': 'https://openalex.org/S72350973', 'display_name': 'Clinical Infectious Diseases', 'issn_l': '1058-4838', 'issn': ['1058-4838', '1537-6591'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc8492116', 'pdf_url': 'https://europepmc.org/articles/pmc8492116?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492116', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/32818963', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/cid/ciaa1204', 'pdf_url': 'https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa1204/33890841/ciaa1204.pdf', 'source': {'id': 'https://openalex.org/S72350973', 'display_name': 'Clinical Infectious Diseases', 'issn_l': '1058-4838', 'issn': ['1058-4838', '1537-6591'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W1984612322', 'https://openalex.org/W1999876505', 'https://openalex.org/W2006658793', 'https://openalex.org/W2017724775', 'https://openalex.org/W2026505095', 'https://openalex.org/W2085986706', 'https://openalex.org/W2106311471', 'https://openalex.org/W2135182325', 'https://openalex.org/W2135486637', 'https://openalex.org/W2141563676', 'https://openalex.org/W2162847806', 'https://openalex.org/W2174399815', 'https://openalex.org/W2185069069', 'https://openalex.org/W2216117396', 'https://openalex.org/W2229168473', 'https://openalex.org/W2507739565', 'https://openalex.org/W2790841582', 'https://openalex.org/W615254675'], 'related_works': ['https://openalex.org/W4386640344', 'https://openalex.org/W2408941662', 'https://openalex.org/W2388650260', 'https://openalex.org/W2379625169', 'https://openalex.org/W2368283414', 'https://openalex.org/W2367231396', 'https://openalex.org/W2359884329', 'https://openalex.org/W2318402467', 'https://openalex.org/W2111915950', 'https://openalex.org/W2052760550'], 'abstract_inverted_index': {'Acute': [0], 'vulvovaginal': [1], 'candidiasis': [2], '(VVC)': [3], 'is': [4, 23], 'common': [5], 'among': [6], 'women,': [7], 'but': [8], 'current': [9], 'azole': [10], 'antifungal': [11], 'treatments': [12], 'are': [13], 'often': [14], 'associated': [15], 'with': [16, 27, 51, 58, 125], 'safety': [17, 44], 'and': [18, 43, 128, 157, 176, 187], 'resistance': [19], 'issues.': [20], 'VT-1161': [21, 46, 71, 147, 152, 158, 183, 225], '(oteseconazole)': [22], 'an': [24, 59], 'oral': [25], 'agent': [26], 'increased': [28], 'selectivity': [29], 'for': [30, 77, 83, 92, 114], 'fungal': [31], 'CYP51.': [32], 'In': [33], 'this': [34], 'phase': [35], '2': [36], 'clinical': [37], 'study,': [38], 'we': [39], 'evaluated': [40], 'the': [41, 121, 139, 146, 165, 182, 190], 'efficacy': [42], 'of': [45, 62, 101, 123, 136, 196, 213, 236], 'vs': [47, 164, 185], 'fluconazole': [48, 102, 166, 191], 'in': [49, 138, 145, 181, 189], 'participants': [50, 124, 137, 180, 214], 'moderate': [52], 'to': [53, 69, 96, 107, 208], 'severe': [54], 'acute': [55, 60, 109], 'VVC.Participants': [56], 'presenting': [57], 'episode': [61], 'VVC': [63], '(n': [64], '=': [65], '55)': [66], 'were': [67, 112, 170, 210], 'randomized': [68], 'receive': [70, 97], '300': [72, 148], 'mg': [73, 81, 88, 104, 149, 154, 160], 'once': [74], 'daily': [75, 90], '(q.d.)': [76], '3': [78, 84, 93, 175], 'days,': [79, 85], '600': [80, 87, 153, 159], 'q.d.': [82, 150, 155], 'or': [86, 95, 203], 'twice': [89], '(b.i.d.)': [91], 'days': [94], 'a': [98], 'single': [99], 'dose': [100, 106, 231], '150': [103], '(FDA-approved': [105], 'treat': [108], 'VVC).': [110], 'Participants': [111], 'followed': [113], '6': [115, 177, 234], 'months.': [116], 'The': [117], 'primary': [118], 'outcome': [119], 'was': [120, 226], 'proportion': [122, 135], 'therapeutic': [126, 143, 220], '(clinical': [127], 'mycological)': [129], 'cure': [130, 144, 221], 'at': [131, 222, 229], 'day': [132, 223], '28.A': [133], 'larger': [134], 'per-protocol': [140], 'population': [141], 'experienced': [142], '(75.0%),': [151], '(85.7%),': [156], 'b.i.d.': [161], '(78.6%)': [162], 'groups': [163, 184, 218], 'group': [167], '(62.5%);': [168], 'differences': [169], 'not': [171], 'statistically': [172], 'significant.': [173], 'At': [174], 'months,': [178], 'no': [179], '28.5%': [186], '46.1%': [188], 'group,': [192], 'respectively,': [193], 'had': [194], 'evidence': [195], 'mycological': [197], 'recurrence.': [198], 'No': [199], 'serious': [200], 'adverse': [201, 205], 'events': [202, 206], 'treatment-emergent': [204], 'leading': [207], 'discontinuation': [209], 'reported.The': [211], 'majority': [212], 'across': [215], 'all': [216, 230], 'treatment': [217], 'achieved': [219], '28.': [224], 'well': [227], 'tolerated': [228], 'levels': [232], 'through': [233], 'months': [235], 'follow-up.NCT01891331.': [237]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3080884461', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 15}, {'year': 2022, 'cited_by_count': 17}, {'year': 2021, 'cited_by_count': 9}], 'updated_date': '2024-12-13T00:51:38.295760', 'created_date': '2020-09-01'}