Title: A rapid method for assessing ventilation post-perfusion: The use of Tc-99m DTPA aerosol and computer subtraction
Abstract:Aerosol ventilation studies currently require considerable cooperation on the part of the patient and may result in lengthy study periods or potentially high doses of radiation. This report validates ...Aerosol ventilation studies currently require considerable cooperation on the part of the patient and may result in lengthy study periods or potentially high doses of radiation. This report validates an aerosol method which minimizes patients study time and attempts to keep radiation exposure to a minimum. Seventeen patients underwent a control pre-perfusion Tc-99m DTPA aerosol multi-view study prior to a 2 mCi Tc-99m MMA multi-view perfusion study. The patient was then placed in an ''optimum position'' to maximize a visual abnormality seen on perfusion. Nebulized Tc-99m DTPA at two times the original concentration for the pre-perfusion aerosol was again inhaled. Images were obtained on film for two minutes and on computer in one minute frame increments for two minutes. The ''perfusion'' image consisted of counts from the Tc-99m MAA and Tc-99m DTPA pre-perfusion aerosol. This image was used as a ''mask'' and subtracted from the post-perfusion aerosol image. The resultant image represented the post-perfusion aerosol counts only. With the patient acting as his own control all 17 patients demonstrated no significant differences between the pre-perfusion image and the post perfusion computer subtracted image. The authors conclude that post-perfusion aerosol imaging equivalent to pre-perfusion may be obtained using as little asmore » one minute of imaging time. An entire study can be performed in 5-6 minutes or less allowing for all of the advantages of post-perfusion ventilation imaging while not sacrificing the quality of a pre-perfusion test.« lessRead More
Publication Year: 1984
Publication Date: 1984-01-01
Language: en
Type: article
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