Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3045867367', 'doi': 'https://doi.org/10.1091/mbc.e20-02-0160', 'title': 'XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions', 'display_name': 'XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions', 'publication_year': 2020, 'publication_date': '2020-09-15', 'ids': {'openalex': 'https://openalex.org/W3045867367', 'doi': 'https://doi.org/10.1091/mbc.e20-02-0160', 'mag': '3045867367', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32726183', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7550701'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1091/mbc.e20-02-0160', 'pdf_url': 'https://www.molbiolcell.org/doi/pdf/10.1091/mbc.E20-02-0160', 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.molbiolcell.org/doi/pdf/10.1091/mbc.E20-02-0160', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5052187666', 'display_name': 'Brianna R. King', 'orcid': 'https://orcid.org/0000-0002-2982-6936'}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Brianna R. King', 'raw_affiliation_strings': ['Department of Biochemistry, University of Washington, Seattle, WA 98195'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Washington, Seattle, WA 98195', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038155883', 'display_name': 'Michelle Moritz', 'orcid': 'https://orcid.org/0000-0003-3811-5623'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michelle Moritz', 'raw_affiliation_strings': ['Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035519845', 'display_name': 'Haein Kim', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Haein Kim', 'raw_affiliation_strings': ['Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081416783', 'display_name': 'David A. Agard', 'orcid': 'https://orcid.org/0000-0003-3512-695X'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David A. Agard', 'raw_affiliation_strings': ['Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074569982', 'display_name': 'Charles L. Asbury', 'orcid': 'https://orcid.org/0000-0002-0143-5394'}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Charles L. Asbury', 'raw_affiliation_strings': ['Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5022826364', 'display_name': 'Trisha N. Davis', 'orcid': 'https://orcid.org/0000-0003-4797-3152'}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Trisha N. Davis', 'raw_affiliation_strings': ['Department of Biochemistry, University of Washington, Seattle, WA 98195'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Washington, Seattle, WA 98195', 'institution_ids': ['https://openalex.org/I201448701']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5022826364'], 'corresponding_institution_ids': ['https://openalex.org/I201448701'], 'apc_list': None, 'apc_paid': None, 'fwci': 2.413, 'has_fulltext': False, 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.999862, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '31', 'issue': '20', 'first_page': '2187', 'last_page': '2194'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13526', 'display_name': '14-3-3 Proteins: Structure, Function, and Regulation', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin-Proteasome Proteolytic Pathway', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/microtubule-nucleation', 'display_name': 'Microtubule nucleation', 'score': 0.8554924}, {'id': 'https://openalex.org/keywords/microtubules', 'display_name': 'Microtubules', 'score': 0.570965}, {'id': 'https://openalex.org/keywords/microtubule-associated-protein', 'display_name': 'Microtubule-associated protein', 'score': 0.55045706}, {'id': 'https://openalex.org/keywords/apoptosis-regulation', 'display_name': 'apoptosis regulation', 'score': 0.512593}, {'id': 'https://openalex.org/keywords/cell-cycle-control', 'display_name': 'Cell Cycle Control', 'score': 0.507923}], 'concepts': [{'id': 'https://openalex.org/C84425145', 'wikidata': 'https://www.wikidata.org/wiki/Q422492', 'display_name': 'Tubulin', 'level': 3, 'score': 0.9294388}, {'id': 'https://openalex.org/C61048295', 'wikidata': 'https://www.wikidata.org/wiki/Q909022', 'display_name': 'Nucleation', 'level': 2, 'score': 0.9171266}, {'id': 'https://openalex.org/C20418707', 'wikidata': 'https://www.wikidata.org/wiki/Q189933', 'display_name': 'Microtubule', 'level': 2, 'score': 0.91537166}, {'id': 'https://openalex.org/C94921385', 'wikidata': 'https://www.wikidata.org/wiki/Q12134483', 'display_name': 'Microtubule nucleation', 'level': 5, 'score': 0.8554924}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.63509136}, {'id': 'https://openalex.org/C61081601', 'wikidata': 'https://www.wikidata.org/wiki/Q1102066', 'display_name': 'Microtubule-associated protein', 'level': 3, 'score': 0.55045706}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.50945765}, {'id': 'https://openalex.org/C82381507', 'wikidata': 'https://www.wikidata.org/wiki/Q416878', 'display_name': 'Polymerase', 'level': 3, 'score': 0.48176098}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.45726618}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.27835912}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.24970874}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.18873104}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.17838544}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.16641992}, {'id': 'https://openalex.org/C10447061', 'wikidata': 'https://www.wikidata.org/wiki/Q190769', 'display_name': 'Centrosome', 'level': 4, 'score': 0.1628989}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D008869', 'descriptor_name': 'Microtubule-Associated Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014404', 'descriptor_name': 'Tubulin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008869', 'descriptor_name': 'Microtubule-Associated Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008869', 'descriptor_name': 'Microtubule-Associated Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066329', 'descriptor_name': 'Protein Aggregates', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D066329', 'descriptor_name': 'Protein Aggregates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014404', 'descriptor_name': 'Tubulin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D014404', 'descriptor_name': 'Tubulin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1091/mbc.e20-02-0160', 'pdf_url': 'https://www.molbiolcell.org/doi/pdf/10.1091/mbc.E20-02-0160', 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://escholarship.org/uc/item/78v4q272', 'pdf_url': 'https://escholarship.org/content/qt78v4q272/qt78v4q272.pdf?t=rja4g0', 'source': {'id': 'https://openalex.org/S4306400115', 'display_name': 'eScholarship (California Digital Library)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2801248553', 'host_organization_name': 'California Digital Library', 'host_organization_lineage': ['https://openalex.org/I2801248553'], 'host_organization_lineage_names': ['California Digital Library'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550701', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2020.05.21.109561', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/32726183', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1091/mbc.e20-02-0160', 'pdf_url': 'https://www.molbiolcell.org/doi/pdf/10.1091/mbc.E20-02-0160', 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W1503916414', 'https://openalex.org/W1555174091', 'https://openalex.org/W1633549441', 'https://openalex.org/W1888780705', 'https://openalex.org/W1974111066', 'https://openalex.org/W1978492020', 'https://openalex.org/W1987637559', 'https://openalex.org/W1993485613', 'https://openalex.org/W1993572893', 'https://openalex.org/W1997535646', 'https://openalex.org/W1997589405', 'https://openalex.org/W2002267883', 'https://openalex.org/W2002603998', 'https://openalex.org/W2010286179', 'https://openalex.org/W2012083512', 'https://openalex.org/W2013995570', 'https://openalex.org/W2015507510', 'https://openalex.org/W2016283389', 'https://openalex.org/W2022046477', 'https://openalex.org/W2030808769', 'https://openalex.org/W2032920533', 'https://openalex.org/W2033306271', 'https://openalex.org/W2037415133', 'https://openalex.org/W2041672262', 'https://openalex.org/W2046134480', 'https://openalex.org/W2046518122', 'https://openalex.org/W2048982317', 'https://openalex.org/W2063734769', 'https://openalex.org/W2075734600', 'https://openalex.org/W2090834457', 'https://openalex.org/W2093012794', 'https://openalex.org/W2100455255', 'https://openalex.org/W2104929139', 'https://openalex.org/W2109777125', 'https://openalex.org/W2117121945', 'https://openalex.org/W2118562210', 'https://openalex.org/W2120558717', 'https://openalex.org/W2132629607', 'https://openalex.org/W2145264628', 'https://openalex.org/W2159447001', 'https://openalex.org/W2162956972', 'https://openalex.org/W2258283902', 'https://openalex.org/W2294993303', 'https://openalex.org/W2620662403', 'https://openalex.org/W2802035309', 'https://openalex.org/W2804899594', 'https://openalex.org/W2995545804', 'https://openalex.org/W3034693706', 'https://openalex.org/W3138289039'], 'related_works': ['https://openalex.org/W4388784901', 'https://openalex.org/W4388784889', 'https://openalex.org/W2528453622', 'https://openalex.org/W2107561141', 'https://openalex.org/W2079016385', 'https://openalex.org/W2070191397', 'https://openalex.org/W2031263977', 'https://openalex.org/W2024145976', 'https://openalex.org/W1974089612', 'https://openalex.org/W1901412126'], 'abstract_inverted_index': {'Microtubule': [0], 'nucleation': [1, 24, 53, 130, 165], 'is': [2, 25], 'spatiotemporally': [3], 'regulated': [4], 'in': [5, 23, 56, 83, 117, 143], 'cells': [6], 'by': [7, 147, 152, 171], 'several': [8], 'known': [9], 'molecules,': [10], 'including': [11], 'the': [12, 16, 52, 66, 99, 159], 'template': [13], 'γ-tubulin': [14, 113, 148], 'and': [15, 94, 112, 149], 'polymerase': [17, 35], 'XMAP215.': [18, 153], 'The': [19], 'role': [20], 'of': [21, 101, 126, 161, 173], 'XMAP215': [22, 44, 70, 111, 157], 'under': [26], 'debate,': [27], 'specifically': [28], 'whether': [29], 'it': [30], 'acts': [31, 37], 'independently': [32], 'as': [33, 45], 'a': [34, 46], 'or': [36, 170], 'dependently': [38], 'with': [39, 87], 'γ-tubulin.': [40, 174], 'We': [41, 75, 154], 'first': [42], 'confirm': [43], 'classically': [47], 'defined': [48], 'nucleator': [49], 'that': [50, 77, 110, 156], 'reduces': [51], 'lag': [54], 'seen': [55], 'bulk': [57], 'tubulin': [58], 'assembly.': [59], 'Secondly,': [60], 'using': [61], 'deletion': [62], 'constructs,': [63], 'we': [64, 108], 'probe': [65], 'domain': [67], 'requirements': [68], 'for': [69], 'to': [71, 80, 90, 163], 'promote': [72, 114], 'microtubule': [73, 129], 'nucleation.': [74], 'show': [76, 109], 'its': [78, 88], 'ability': [79, 89], 'nucleate': [81], 'microtubules': [82, 93], 'purified': [84], 'solutions': [85], 'correlates': [86], 'elongate': [91], 'existing': [92, 164], 'does': [95], 'not': [96, 120], 'depend': [97], 'on': [98], 'number': [100], 'tumor': [102], 'overexpressed': [103], 'gene': [104], '(TOG)': [105], 'domains.': [106], 'Finally,': [107], 'αβ-tubulin': [115], 'assembly': [116], 'an': [118], 'additive,': [119], 'synergistic,': [121], 'manner.': [122], 'Thus,': [123], 'their': [124], 'modes': [125], 'action': [127], 'during': [128], 'are': [131, 137], 'distinct.': [132], 'These': [133], 'findings': [134], 'suggest': [135], 'there': [136], 'at': [138], 'least': [139], 'two': [140], 'independent': [141], 'processes': [142], 'nucleation,': [144], 'one': [145, 150], 'promoted': [146, 151], 'propose': [155], 'accelerates': [158], 'addition': [160], 'subunits': [162], 'intermediates': [166], 'formed': [167], 'either': [168], 'spontaneously': [169], 'oligomers': [172], '[Media:': [175], 'see': [176], 'text].': [177]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3045867367', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 2}], 'updated_date': '2024-09-01T08:35:24.171808', 'created_date': '2020-08-03'}