Title: Prevention of Mother to Child Transmission of Zika Virus and Associated Teratogenic Effects
Abstract: Background: Zika virus (ZIKV), a mosquito-borne flavivirus the same vector that causes Dengue and Chikungunya. ZIKV originated from Uganda and was first discovered in monkeys at Zika forest in 1947. Historically, ZIKV causes mild and self-limiting symptoms which can be observed in only 20folds of infected individuals. Recently, in 2015, ZIKV imaged in Brazil and has been linked to serious neurological complications including microcephaly. In 2016, the World Health Organization declared this fact as “Public Health Emergency” Objective: Review on possible mother to child transmission of ZIKV in utero and its related teratogenic effect. Method: Studies both in human and animal models revealed a relationship between ZIKV infection in pregnancy and neurological effects such as microcephaly in fetus and neonates.
Result: ZIKV has been linked with microcephaly especially when symptoms emerged in a pregnant woman during first and early second trimester.
Conclusion: Although there is a linkage between ZIKV and neurological effects such as microcephaly, most people still doubting as to whether the emerging problem of microcephaly is related to ZIKV infections which is known to present with mild and self-limiting symptoms.
Publication Year: 2020
Publication Date: 2020-06-02
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot