Title: The relationship between testosterone levels and Peyronie’s disease
Abstract: AndrologiaVolume 52, Issue 9 e13727 ORIGINAL ARTICLE The relationship between testosterone levels and Peyronie's disease Osman Can, Corresponding Author Osman Can [email protected] orcid.org/0000-0003-1329-6034 Department of Urology, Basaksehir City Hospital, Istanbul, Turkey Correspondence Osman Can, Okmeydani Training and Research Hospital, Kaptanpasa District, Sisli, Istanbul, Turkey. Email: [email protected] for more papers by this authorSait Özbir, Sait Özbir orcid.org/0000-0002-9300-6860 Department of Urology, Cemil Taşcıoglu City Hospital, Istanbul, TurkeySearch for more papers by this authorHasan Anil Atalay, Hasan Anil Atalay orcid.org/0000-0002-2977-1680 Department of Urology, Beylikduzu State Hospital, Istanbul, TurkeySearch for more papers by this authorSüleyman Sami Çakır, Süleyman Sami Çakır orcid.org/0000-0002-0211-3450 Department of Urology, Atlas University, Medicine Hospital, Istanbul, TurkeySearch for more papers by this authorMehmet Gökhan Culha, Mehmet Gökhan Culha orcid.org/0000-0003-4059-2293 Department of Urology, Cemil Taşcıoglu City Hospital, Istanbul, TurkeySearch for more papers by this authorHalil Lütfi Canat, Halil Lütfi Canat orcid.org/0000-0001-6481-7907 Department of Urology, Cemil Taşcıoglu City Hospital, Istanbul, TurkeySearch for more papers by this author Osman Can, Corresponding Author Osman Can [email protected] orcid.org/0000-0003-1329-6034 Department of Urology, Basaksehir City Hospital, Istanbul, Turkey Correspondence Osman Can, Okmeydani Training and Research Hospital, Kaptanpasa District, Sisli, Istanbul, Turkey. Email: [email protected] for more papers by this authorSait Özbir, Sait Özbir orcid.org/0000-0002-9300-6860 Department of Urology, Cemil Taşcıoglu City Hospital, Istanbul, TurkeySearch for more papers by this authorHasan Anil Atalay, Hasan Anil Atalay orcid.org/0000-0002-2977-1680 Department of Urology, Beylikduzu State Hospital, Istanbul, TurkeySearch for more papers by this authorSüleyman Sami Çakır, Süleyman Sami Çakır orcid.org/0000-0002-0211-3450 Department of Urology, Atlas University, Medicine Hospital, Istanbul, TurkeySearch for more papers by this authorMehmet Gökhan Culha, Mehmet Gökhan Culha orcid.org/0000-0003-4059-2293 Department of Urology, Cemil Taşcıoglu City Hospital, Istanbul, TurkeySearch for more papers by this authorHalil Lütfi Canat, Halil Lütfi Canat orcid.org/0000-0001-6481-7907 Department of Urology, Cemil Taşcıoglu City Hospital, Istanbul, TurkeySearch for more papers by this author First published: 26 June 2020 https://doi.org/10.1111/and.13727Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Aetiologic and predisposing factors are still controversial about Peyronie's disease (PD). However, it is thought to be the result of connective tissue disorder or healing defect. Androgens are known to affect collagen metabolism and wound healing in the body. The aim of this study was to investigate the relationship between PD and low testosterone levels. One hundred and forty-seven Peyronie patients and 137 healthy volunteers were included in the study. In both groups, demographic data, medical history, physical examination and erectile capacity were recorded. Blood samples were collected from all subjects in the early morning hours after an overnight fast. The mean level of serum total testosterone was lower in men with PD compared with the controls (3.9 ± 1.1 vs. 4.2 ± 1.7 ng/ml respectively) (p = .062). However, statistically significant relationship was not found between PD and low serum testosterone levels. There was no significant correlation between penile plaque dimension or penile curvature degree and testosterone levels. Large randomised-controlled prospective studies are needed to reveal this possible association. Volume52, Issue9October 2020e13727 RelatedInformation