Publication Information

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'the': [20, 56, 130, 157, 163, 179, 189, 200, 207, 214], 'nucleotide-binding': [21], 'domain-like': [22], 'receptor': [23], 'protein': [24, 143, 166], '3': [25], '(NLRP3)': [26], 'inflammasome': [27, 132], 'major': [30], 'pathogenic': [31], 'mechanism': [32], 'AKI': [34, 72], 'induced': [35, 74], 'by': [36, 77, 196], 'lipopolysaccharide': [37], '(LPS).': [38], 'Autophagy,': [39], 'process': [41], 'intracellular': [43], 'degradation': [44], 'related': [45], 'to': [46], 'renal': [47, 123, 215], 'homeostasis,': [48], 'effectively': [49], 'restricts': [50], 'inflammatory': [51], 'responses.': [52], 'Herein,': [53], 'we': [54, 155, 212], 'explored': [55], 'potential': [57], 'protective': [58, 180, 190, 216], 'mechanisms': [59], 'dexmedetomidine': [61], '(DEX),': [62], 'which': [63, 203], 'has': [64], 'confirmed': [65], 'anti-inflammatory': [66], 'effects,': [67], 'on': [68, 162], 'LPS-induced': [69], 'AKI.': [70, 227], 'Methods.': [71], 'was': [73], 'in': [75], 'rats': [76, 86], 'injecting': [78], '10': [79], 'mg/kg': [80], 'LPS': [82], 'intraperitoneally': [83, 112], '(i.p.).': [84], 'Wistar': [85], 'received': [87], 'intraperitoneal': [88, 98], 'injection': [89, 99], 'DEX': [91, 117, 120, 126, 149, 161, 193, 219], '(30': [92], 'µg/kg)': [93, 105], '30': [94, 114], 'min': [95, 115], 'before': [96, 116], 'an': [97], 'LPS.': [101], 'Atipamezole': [102], '(ATI)': [103], '(250': [104], 'and': [106, 133, 138, 144, 175, 220], '3-methyladenine': [107], '(3-MA)': [108], '(15': [109], 'mg/kg)': [110], 'were': [111, 194], 'injected': [113], 'injection.': [118], 'Results.': [119], 'significantly': [121, 151, 177], 'attenuated': [122], 'injury.': [124], 'Furthermore,': [125], 'decreased': [127, 204], 'activation': [128, 205], 'NLRP3': [131, 208], 'expression': [134], 'interleukins': [136], '1β': [137], '18.': [139], 'In': [140], 'addition,': [141], 'autophagy-related': [142], 'gene': [145], 'analysis': [146], 'indicated': [147], 'that': [148, 188], 'could': [150], 'enhance': [152], 'autophagy.': [153], 'Finally,': [154], 'verified': [156, 213], 'pharmacological': [158], 'effects': [159, 181, 191, 217], "5'-adenosine": [164], 'monophosphate-activated': [165], 'kinase': [167], '(AMPK)/mechanistic': [168], 'target': [169], 'rapamycin': [171], '(mTOR)': [172], 'pathway.': [173], 'Atip': [174], '3-MA': [176], 'reversed': [178], 'DEX.': [183], 'Conclusions.': [184], 'Our': [185], 'results': [186], 'suggest': [187], 'mediated': [195], 'enhanced': [197], 'autophagy': [198], 'via': [199], 'α2-adrenoreceptor/AMPK/mTOR': [201], 'pathway,': [202], 'inflammasome.': [209], 'Above': [210], 'all,': [211], 'offer': [221], 'new': [223], 'treatment': [224], 'strategy': [225], 'for': [226]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3037112829', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 19}, {'year': 2022, 'cited_by_count': 16}, {'year': 2021, 'cited_by_count': 8}], 'updated_date': '2024-12-24T00:45:37.984545', 'created_date': '2020-07-02'}