Title: Prognostic factors for surgical margin status and recurrence in partial nephrectomy
Abstract: International Journal of Clinical PracticeVolume 74, Issue 10 e13587 ORIGINAL PAPER Prognostic factors for surgical margin status and recurrence in partial nephrectomy Hüseyin C. Demirel, Hüseyin C. Demirel Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorSedat Çakmak, Sedat Çakmak Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorAbdullah H. Yavuzsan, Abdullah H. Yavuzsan Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorCumhur Yeşildal, Cumhur Yeşildal Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorSemih Türk, Semih Türk Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorAyhan Dalkılınç, Ayhan Dalkılınç Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorSinan L. Kireççi, Sinan L. Kireççi Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorEmre Tokuç, Corresponding Author Emre Tokuç [email protected] orcid.org/0000-0002-5885-9278 Department of Urology, Sultanbeyli State Hospital, Istanbul, Turkey Correspondence Emre Tokuç, Battalgazi Mah. No. 64, Sultanbeyli, Istanbul, Turkey. Email: [email protected] for more papers by this authorKaya Horasanlı, Kaya Horasanlı Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this author Hüseyin C. Demirel, Hüseyin C. Demirel Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorSedat Çakmak, Sedat Çakmak Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorAbdullah H. Yavuzsan, Abdullah H. Yavuzsan Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorCumhur Yeşildal, Cumhur Yeşildal Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorSemih Türk, Semih Türk Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorAyhan Dalkılınç, Ayhan Dalkılınç Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorSinan L. Kireççi, Sinan L. Kireççi Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this authorEmre Tokuç, Corresponding Author Emre Tokuç [email protected] orcid.org/0000-0002-5885-9278 Department of Urology, Sultanbeyli State Hospital, Istanbul, Turkey Correspondence Emre Tokuç, Battalgazi Mah. No. 64, Sultanbeyli, Istanbul, Turkey. Email: [email protected] for more papers by this authorKaya Horasanlı, Kaya Horasanlı Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, TurkeySearch for more papers by this author First published: 18 June 2020 https://doi.org/10.1111/ijcp.13587Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Purpose To evaluate the prognostic factors affecting the surgical margin and recurrence in patients who underwent partial nephrectomy (PN) for renal masses. Materials and Methods Data of 125 patients who underwent open or laparoscopic PN because of renal mass between January 2006 and January 2019 were analysed retrospectively. Demographic data, habits, additional diseases, clinical and laboratory findings, operational data, the morphology of the tumour in computerised tomography or magnetic-resonance imaging and follow-up data were scanned and acquired via our hospital's system and archive. Results Average age was 54.4, male-female ratio was 1.55 and average tumour size was 3.31 cm. One hundred and four patients had malignant pathology and 21 were benign. Positive surgical margin (PSM) rate was 5.6% and recurrence rate was 3.2%. Average follow-up was 47.4 months. Pathological size of the tumour was larger (P = .006), warm-ischemia period was lower (P = .003) and PADUA score was higher (P = .015) in open technique. Tumour size and tumour stage were statistically higher in patients with recurrence (P = .009, P < .001, respectively). There was a significantly higher PSM ratio in mandatory indication group than elective indication group (P = .025). No statistically significant difference was observed between surgical margin positivity and tumour size, Fuhrman grades, PADUA scores, RENAL scores and C-index. (P > .05). Conclusion Surgical margin positivity after PN is not significantly associated with tumour characteristics and anatomical scoring systems. Surgical indication for PN has a direct influence on PSM rates. Tumour size and stage after PN are valuable parameters in evaluating the recurrence risk. Volume74, Issue10October 2020e13587 RelatedInformation