Title: Modern applications of cryosurgery in oncology
Abstract: Brief history of cryosurgeryIn 11 th century, 980-1037 Cold is used for anesthetic property [4].Hippocrate stated that the use of cold water in an acute gout attack was used with success on himself [5], in 1650.In 16th century , 1661 effect of cold as an anaesthetic [6].In Russian campaign cold and snow applied to reduce pain and haemorrhage.During the Russian campaign the temperature below -50° C , the effect of cold has a sedative effect on the brain and nervous system.in1777 cold showed the destructive effect when used in the treatment of tumours.[7][8][9][10] In 1851 so many studies has been conducted on cold or ice and it applications as anesthetic and in cancer at -12 o C to -55 o C. In 1882 Paris , use extreme cold as produced by methyl chloride to treat tumours [11].In 1833 ice cold water is used to treat chronic cervicitis.In 19th century , certain tumours are treated by freezing,the effects of cold have been used in medicine for a very long time.The term "cryo" is used incorrectly in