Title: Research progress of chemokine CXCL13 and its receptor CXCR5 in diseases
Abstract:Chemokines are a group of small molecule proteins that belong to the cytokine family and interact with G-protein coupled receptor superfamily. Chemokines interact with their receptors and their primar...Chemokines are a group of small molecule proteins that belong to the cytokine family and interact with G-protein coupled receptor superfamily. Chemokines interact with their receptors and their primary function is to recruit immune cells, activate lymphocytes and induce inflammatory response. In recent years, a large number of studies have shown that chemotactic factor CXCL13 and its receptor CXCR5 are involved in autoimmune diseases as well as tumor growth, invasion, and metastasis. In this article, recent advances in research on related diseases of CXCL13 and its receptor CXCR5 are reviewed.
Key words:
Chemokine CXCL13; Receptors, CXCR5; Autoimmune diseases; NeoplasmsRead More
Publication Year: 2019
Publication Date: 2019-12-10
Language: en
Type: article
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