Title: Analysis of factors for lateral neck lymph node metastasis in cN0 papillary thyroid carcinoma
Abstract: Objective
To explore the lateral neck lymph node metastasis (LNM) in patients affected by papillary thyroid carcinoma (PTC) with clinically negative neck (cN0-PTC) and to discuss the necessity of prophylactic lateral neck lymph node dissection.
Methods
Clinical data of 651 cN0-PTC patients who underwnt surgical procedure in Tumor Hospital of Zhengzhou University from Jan. 2012 to May. 2015 were retrospectively analyzed. Chi-square test was used for univariate analysis.
Results
Of the 651 cN0-PTC patients, 62.9% had LNM (51.3% in central neck, 41.0% in lateral neck, and 11.7% with skip metastasis) . The lateral neck metastasis rate was 50.9% in men and 37.7% in women (P 1.0 cm and 25.9% in patients with tumor diameter ≤1.0 cm (P 45 years (P>0.05) .
Conclusion
Central neck dissection should be performed in all cN0-PTC patients. Prophylactic lateral neck dissection should beselectively performed in cN0-PTC patients with following high-risk factors: male, tumor diameter >1.0 cm, multifocal cancer, extrathyroidal extention, ≥3 positive nodes in central neck and upper lobe cancer.
Key words:
Papillary thyroid carcinoma; Lateral neck compartment; Lymph node metastasis; Lymph node dissection
Publication Year: 2017
Publication Date: 2017-12-25
Language: en
Type: article
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