Title: Karyotype Analysis of 58 cases myelodysplastie synarom
Abstract: Objective To explore theralue of karyotype analysis in MDS for diagnosis, cure and progno-sis. Methods Chromosome analysis was performed in 58 cases of MDS using the short-term culture of bone marrow eell and R-banding technique, meanwhile,their clinical progress was followed up. Results Karyotype a-nalysis showed that 31 eases(53.4%) had elonal Karyotypie abnormalities. The nost common chromosomal ab-errations included +8 and high complex karyotypic, and then-7/7q-In the following up, 19 eases (30.5%) transformed into acute leukemia. Conclusion The Karyotype analysis is very important for diagnosis, cure and prognosis of MDS.
Key words:
Myelodysplastic syndrome; Chromosome; Karyotype
Publication Year: 2009
Publication Date: 2009-03-25
Language: en
Type: article
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