Title: Relationship between diameter of liver hemangioma and operation risk
Abstract:Objective
To explore the relationship between diameter of liver hemangioma and operation risk.
Methods
The clinical data of 362 patients with liver hemangioma who were admitted to the PLA Gener...Objective
To explore the relationship between diameter of liver hemangioma and operation risk.
Methods
The clinical data of 362 patients with liver hemangioma who were admitted to the PLA General Hospital from January 2006 to January 2014 were retrospectively analyzed. All patients were divided into the 3 groups according to diameter of gross specimen, 217 with tumor diameter≥5 cm and ≤10 cm in the large hemangioma group, 119 with tumor diameter>10 cm and ≤20 cm in the giant hemangioma group and 26 with tumor diameter≥20 cm in the extremely large hemangioma group. The operation method included open surgery and laparoscopic surgery. Hepatectomy and enucleation of liver hemangioma were major operation procedures. The operation time, volume of intraoperative blood loss, number of patients with intraoperative blood transfusion, number of patients with postoperative complications and duration of hospital stay were evaluated. Count data were analyzed using the chi-square test. Measurement data with normal distribution were presented as ±s, and comparison among groups was analyzed using the ANOVA. Skewed distribution data were described as M(P25, P75), comparison among groups was analyzed by Kruskal-wallis test and pairwise comparison was done by the Mann-Whitney U test.
Results
All patients underwent operation successfully without perioperative death, including 315 receiving open surgery (175 in the large hemangioma group, 114 in the giant hemangioma group and 26 in the extremely large hemangioma group) and 47 receiving laparoscopic surgery (42 in the large hemangioma group and 5 in the giant hemangioma group). The operation time, volume of intraoperative blood loss, number of patients with blood transfusion, number of patients with postoperative complications and duration of hospital stay were 160 minutes (125 minutes, 205 minutes), 300 mL (100 mL, 500 mL), 31, 5 and 8 days (7 days, 9 days) in the large hemangioma group, 220 minutes (175 minutes, 275 minutes), 500 mL (300 mL, 1 000mL), 36, 5 and 9 days (8 days, 10 days) in the giant hemangioma group, 330 minutes (280 minutes, 420 minutes), 1 975 mL (800 mL, 4 000mL), 20, 7 and 11 days (9 days, 13 days) in the extremely large hemangioma group, respectively, with significant differences (χ2=84.24, 80.94, 53.65, 31.54, 47.67, P 0.05). There were significant differences in the number of patients with postoperative complications between large hemangioma group and extremely large hemangioma group and between giant hemangioma group and extremely large hemangioma group (χ2=24.96, 11.67, P<0.05).
Conclusions
Diameber of liver hemangioma is associated with operation time, volume of intraoperative blood loss, number of patients with intraoperative blood transfusion, number of patients with postoperative complications and duration of hospital stay, and there is a high risk in the surgical treatment of patients with liver hemangioma diameter≥20 cm.
Key words:
Liver hemangioma; Hepatectomy; ComplicationRead More
Publication Year: 2015
Publication Date: 2015-09-20
Language: en
Type: article
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