Title: Relationship between anti-apoptotic mechanisms of Survivin and lung cancer
Abstract: Survivin has an ability to inhibit cell apotosis and regulate cell cycle.It is selectively over-expressed in most human neoplasmas.Recent researches have shown that survivin over expression is associated with the earcinogensis, development, poor prognosis and drug/radiation resistant of lung cancer.Survivin may become a target of early diagnosis and gene therapy for malignant tumors.
Key words:
Lung neoplasms; Apoptosis; Target therapy
Publication Year: 2009
Publication Date: 2009-01-08
Language: en
Type: article
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