Publication Information

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'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3207159343', 'https://openalex.org/W3107471208', 'https://openalex.org/W3102552033', 'https://openalex.org/W3037494779', 'https://openalex.org/W3032821990', 'https://openalex.org/W3031518867', 'https://openalex.org/W3031465342', 'https://openalex.org/W2901740909', 'https://openalex.org/W2901738685', 'https://openalex.org/W2884574799', 'https://openalex.org/W2792705357', 'https://openalex.org/W2765553242', 'https://openalex.org/W2552531062', 'https://openalex.org/W2467199490', 'https://openalex.org/W2393979885', 'https://openalex.org/W2377668232', 'https://openalex.org/W2373126011', 'https://openalex.org/W2357124737', 'https://openalex.org/W2110712886', 'https://openalex.org/W1997773579'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'investigate': [1], 'the': [2, 63, 82, 107, 116, 124, 128, 141, 149, 159, 178, 219, 227, 234, 246, 257, 268, 287], 'expression': [3, 64, 83, 129, 165, 201], 'and': [4, 12, 15, 17, 25, 49, 68, 87, 103, 133, 169, 190, 195, 205, 243, 253, 262, 276], 'clinical': [5, 188], 'significance': [6], 'of': [7, 65, 84, 97, 123, 130, 148, 158, 166, 180, 192, 202, 226, 236, 240, 259, 290], 'CXC': [8], 'chemokine': [9], 'receptors': [10], '1': [11], '2': [13], '(CXCR1': [14], 'CXCR2)': [16], 'CXCL8': [18, 69, 88, 134, 170, 206, 244, 280], 'in': [19, 73, 92, 106, 138, 171, 197, 210, 218, 222, 245, 264, 286, 303], 'peripheral': [20], 'blood': [21], 'mononuclear': [22], 'cells': [23], '(PBMCs)': [24], 'liver': [26, 47, 93, 160, 211], 'biopsy': [27, 94, 212], 'tissues': [28, 213], 'from': [29, 39, 140], 'patients': [30, 41, 45, 172, 247], 'with': [31, 42, 46, 173, 177, 224, 248, 256], 'primary': [32], 'hepatocellular': [33, 304], 'carcinoma': [34], '(PHC).\r\n\r\n\r\nMethods\r\nSerum': [35], 'specimens': [36, 109], 'were': [37, 110, 121, 144, 175, 214], 'collected': [38], '36': [40], 'PHC,': [43], '30': [44], 'cirrhosis': [48, 161], '28': [50], 'healthy': [51, 150, 228], 'subjects.': [52], 'Quantitative': [53], 'real-time': [54], 'polymerase': [55], 'chain': [56], 'reaction': [57], '(qRT-PCR)': [58], 'was': [59, 78], 'performed': [60], 'to': [61, 80], 'measure': [62], 'CXCR1,': [66, 85, 131, 167, 203, 241, 274], 'CXCR2': [67, 86, 132, 168, 204, 242, 275], 'at': [70, 89, 135, 207], 'mRNA': [71, 136], 'level': [72, 91, 137, 209], 'PBMCs.': [74], 'Streptavidin-perosidase': [75], '(SP)': [76], 'immunohistochemistry': [77, 238], 'used': [79], 'detect': [81], 'protein': [90, 99, 208], 'tissues.': [95], 'Levels': [96], 'C-reactive': [98], '(CRP),': [100], 'alpha-fetoprotein': [101], '(AFP)': [102], 'ferritin': [104], '(FER)': [105], 'serum': [108, 198], 'detected': [111], 'by': [112, 233, 273], 'chemiluminescence': [113], 'immunoassay.': [114], 'Then': [115], 'correlations': [117], 'between': [118], 'these': [119], 'markers': [120], 'analyzed.\r\n\r\n\r\nResults\r\nAll': [122], 'results': [125], 'showed': [126], 'that': [127, 267], 'PBMCs': [139], 'PHC': [142, 174, 220, 249], 'group': [143, 152, 162, 221, 230], 'higher': [145], 'than': [146], 'those': [147, 157, 225], 'control': [151, 229], '(P<0.01)': [153], 'as': [154, 156, 231], 'well': [155], '(P<0.05).': [163, 199], 'Up-regulated': [164], 'associated': [176], 'depth': [179], 'tumor': [181], 'invasion,': [182], 'lymph': [183], 'node': [184], 'or': [185], 'distant': [186], 'metastasis,': [187], 'stage': [189], 'levels': [191, 258], 'CRP,': [193], 'AFP': [194], 'FER': [196, 261], 'The': [200], 'also': [215], 'significantly': [216, 251], 'increased': [217, 252], 'comparison': [223], 'indicated': [232], 'result': [235], 'SP': [237], '(P<0.05).\r\n\r\n\r\nConclusion\r\nLevels': [239], 'are': [250], 'positively': [254], 'correlated': [255], 'AFP,': [260], 'CRP': [263], 'serum,': [265], 'suggesting': [266], 'signal': [269], 'transduction': [270], 'process': [271, 289], 'mediated': [272], 'their': [277], 'common': [278], 'ligand': [279], 'may': [281, 294], 'play': [282], 'a': [283, 296], 'key': [284], 'role': [285], 'pathological': [288], 'PHC.': [291], 'This': [292], 'study': [293], 'provide': [295], 'potential': [297], 'new': [298], 'strategy': [299], 'for': [300], 'immune': [301], 'intervention': [302], 'cancer.\r\n\r\n\r\nKey': [305], 'words:': [306], '\r\nPHC;\xa0CXCR1;\xa0CXCR2;\xa0CXCL8;\xa0mRNA;\xa0AFP;\xa0FER;\xa0CRP': [307]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031513180', 'counts_by_year': [], 'updated_date': '2024-12-15T21:08:05.539524', 'created_date': '2020-06-05'}