Publication Information

{'id': 'https://openalex.org/W3031440685', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2017.12.015', 'title': 'The effect and mechanism of salinomycin on the proliferation and apoptosis of adrenal cortical carcinoma SW13 cell line', 'display_name': 'The effect and mechanism of salinomycin on the proliferation and apoptosis of adrenal cortical carcinoma SW13 cell line', 'publication_year': 2017, 'publication_date': '2017-12-08', 'ids': {'openalex': 'https://openalex.org/W3031440685', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2017.12.015', 'mag': '3031440685'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN421213201712/1013726.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764660617', 'display_name': 'Zhonghua shiyan waike zazhi', 'issn_l': '1001-9030', 'issn': ['1001-9030'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 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Zhao', 'raw_affiliation_strings': ['Department of Urology, General Hospital of Guangzhou Military Command of PLA, Guangzhou 510010, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Urology, General Hospital of Guangzhou Military Command of PLA, Guangzhou 510010, China', 'institution_ids': ['https://openalex.org/I4210099466']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101560437', 'display_name': 'Weilie Hu', 'orcid': 'https://orcid.org/0009-0000-0664-6126'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Weilie Hu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5000296373', 'display_name': 'Yi Zhu', 'orcid': 'https://orcid.org/0000-0003-1650-1363'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yi Zhu', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 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[{'score': 0.49, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032662486', 'https://openalex.org/W3029402900', 'https://openalex.org/W3029259567', 'https://openalex.org/W2413690625', 'https://openalex.org/W2388434900', 'https://openalex.org/W2386832524', 'https://openalex.org/W2380071131', 'https://openalex.org/W2379255386', 'https://openalex.org/W2372908771', 'https://openalex.org/W2371312746', 'https://openalex.org/W2370342628', 'https://openalex.org/W2369717833', 'https://openalex.org/W2361640381', 'https://openalex.org/W2361496732', 'https://openalex.org/W2360880591', 'https://openalex.org/W2359277081', 'https://openalex.org/W2356850352', 'https://openalex.org/W2355352234', 'https://openalex.org/W2348769965', 'https://openalex.org/W2347272947'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'study': [1], 'the': [2, 9, 106, 122, 153, 175], 'effect': [3], 'and': [4, 16, 30, 47, 66, 85, 103, 114, 118, 121, 142, 152, 166, 185, 193, 208, 223], 'mechanism': [5], 'of': [6, 18, 83, 98, 108, 177, 191, 211], 'salinomycin': [7, 33, 64, 99], 'on': [8], 'cell': [10, 12, 14, 26, 52, 58, 61, 202, 204], 'proliferation,': [11, 203], 'cycle,': [13, 205], 'apoptosis': [15, 67, 159, 210], 'invasion': [17, 75, 171], 'human': [19, 212], 'adrenal': [20, 213], 'cortical': [21, 214, 230], 'carcinoma': [22, 215], 'SW13': [23, 25, 216], 'cells.\r\n\r\n\r\nMethods\r\nCulture': [24], 'line': [27], 'in': [28], 'vitro': [29], 'treated': [31, 62, 94], 'with': [32, 63, 70, 95], '(30.000,': [34], '20.000,': [35], '10.000,': [36], '5.000,': [37], '2.500,': [38], '1.250,': [39], '0.625,': [40], '0': [41], 'μmol/L)': [42], 'for': [43], '24,': [44, 100], '48,': [45, 101], '72': [46, 102], '96': [48, 104], 'h,': [49], 'then': [50], 'use': [51], 'counting': [53], 'kit-8': [54], '(CCK-8)': [55], 'to': [56, 77], 'assay': [57, 78], 'proliferation.': [59], 'The': [60, 81, 158, 189], 'cycle': [65], 'were': [68, 89, 111, 148, 161, 180, 197], 'determined': [69], 'flow': [71], 'cytometry.': [72], 'Use': [73], 'transwell': [74], 'experiment': [76, 172], 'invasive': [79, 178, 206], 'ability.': [80], 'expression': [82], 'β-catenin': [84, 192], 'B-cell': [86], 'lymphoma/leukemia-2': [87], '(bcl-2)': [88], 'detected': [90], 'by': [91, 218], 'Western': [92], 'blotting.\r\n\r\n\r\nResults\r\nAfter': [93], 'different': [96], 'concentrations': [97], 'hours,': [105], 'proliferation': [107], 'SW-13': [109], 'cells': [110, 146, 179, 217], 'significantly': [112, 200], 'inhibited': [113], 'showed': [115, 136, 173], 'a': [116], 'time': [117], 'concentration': [119, 126], 'dependence': [120], 'corresponding': [123], '50%': [124], 'inhibitory': [125], '(IC50)': [127], 'was': [128, 155], '25.65,': [129], '7.97,': [130], '2.89,': [131], '0.40': [132], 'μmol/L.': [133], 'Flow': [134], 'cytometry': [135], 'that': [137, 174], '4,': [138], '8': [139], 'μmol/L': [140], 'group': [141, 144], 'control': [143], 'G1-period': [145], 'percentage': [147], '(66.250±1.162)%,': [149], '(71.693±0.849)%,': [150], '(59.837±3.043)%': [151], 'difference': [154], 'statistically': [156], 'significant.': [157], 'rates': [160], 'respectively': [162, 184], '9.9%,': [163], '30.3%,': [164], '3.4%': [165], 'have': [167, 186], 'significant': [168, 187], 'difference.': [169, 188], 'Transwell': [170], 'number': [176], '66.800±5.263,': [181], '30.400±2.881,': [182], '17.600±3.050': [183], 'expressions': [190], 'anti-apoptosis': [194, 226], 'bcl-2': [195, 225], 'proteins': [196], 'down-regulated.\r\n\r\n\r\nConclusion\r\nSalinomycin': [198], 'may': [199], 'inhibit': [201], 'ability': [207], 'induce': [209], 'disturb': [219], 'Wnt/β-catenin': [220], 'signal': [221], 'pathway': [222], 'down-regulate': [224], 'protein.\r\n\r\n\r\nKey': [227], 'words:': [228], '\r\nSalinomycin;\xa0Adrenal': [229], 'carcinoma;\xa0SW13': [231], 'cell;\xa0Proliferation;\xa0Cycle;\xa0Apoptosis;\xa0Invasion': [232]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031440685', 'counts_by_year': [], 'updated_date': '2024-12-15T08:18:48.448501', 'created_date': '2020-06-05'}