Publication Information

{'id': 'https://openalex.org/W3031106749', 'doi': 'https://doi.org/10.3760/cma.j.issn.1673-4378.2013.09.003', 'title': 'The protective effects of sodium butyrate on acute lung injury induced by lipopolysaccharide in rats', 'display_name': 'The protective effects of sodium butyrate on acute lung injury induced by lipopolysaccharide in rats', 'publication_year': 2013, 'publication_date': '2013-09-15', 'ids': {'openalex': 'https://openalex.org/W3031106749', 'doi': 'https://doi.org/10.3760/cma.j.issn.1673-4378.2013.09.003', 'mag': '3031106749'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN32176120133409/368753.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764984328', 'display_name': 'Guoji mazuixue yu fusu zazhi', 'issn_l': '1673-4378', 'issn': ['1673-4378'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067092853', 'display_name': 'Ze-jun Ding', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210119987', 'display_name': 'Qingdao Municipal Hospital', 'ror': 'https://ror.org/02jqapy19', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210119987']}, {'id': 'https://openalex.org/I108688024', 'display_name': 'Qingdao University', 'ror': 'https://ror.org/021cj6z65', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I108688024']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ze-jun Ding', 'raw_affiliation_strings': ['Departement of Anesthesiology, Qingdao Municipal Hospital,Qingdao 266011, China'], 'affiliations': [{'raw_affiliation_string': 'Departement of Anesthesiology, Qingdao Municipal Hospital,Qingdao 266011, China', 'institution_ids': ['https://openalex.org/I4210119987', 'https://openalex.org/I108688024']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5015293656', 'display_name': 'Mingjie Sun', 'orcid': 'https://orcid.org/0000-0001-9122-3987'}, 'institutions': [{'id': 'https://openalex.org/I4210119987', 'display_name': 'Qingdao Municipal Hospital', 'ror': 'https://ror.org/02jqapy19', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210119987']}, {'id': 'https://openalex.org/I108688024', 'display_name': 'Qingdao University', 'ror': 'https://ror.org/021cj6z65', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I108688024']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ming-jie Sun', 'raw_affiliation_strings': ['Departement of Anesthesiology, Qingdao Municipal Hospital,Qingdao 266011, China'], 'affiliations': [{'raw_affiliation_string': 'Departement of Anesthesiology, Qingdao Municipal Hospital,Qingdao 266011, China', 'institution_ids': ['https://openalex.org/I4210119987', 'https://openalex.org/I108688024']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 65}, 'biblio': {'volume': '34', 'issue': '09', 'first_page': '779', 'last_page': '782'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.7813, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.7813, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10631', 'display_name': 'Cancer, Hypoxia, and Metabolism', 'score': 0.7466, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11072', 'display_name': 'Peroxisome Proliferator-Activated Receptors', 'score': 0.7449, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/sodium-butyrate', 'display_name': 'Sodium butyrate', 'score': 0.5679259}], 'concepts': [{'id': 'https://openalex.org/C2778754761', 'wikidata': 'https://www.wikidata.org/wiki/Q421804', 'display_name': 'Lipopolysaccharide', 'level': 2, 'score': 0.8036761}, {'id': 'https://openalex.org/C203565725', 'wikidata': 'https://www.wikidata.org/wiki/Q420012', 'display_name': 'Myeloperoxidase', 'level': 3, 'score': 0.73957324}, {'id': 'https://openalex.org/C2777397205', 'wikidata': 'https://www.wikidata.org/wiki/Q275792', 'display_name': 'Saline', 'level': 2, 'score': 0.62710124}, {'id': 'https://openalex.org/C2778942008', 'wikidata': 'https://www.wikidata.org/wiki/Q305004', 'display_name': 'Sodium butyrate', 'level': 3, 'score': 0.5679259}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.5399648}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5075785}, {'id': 'https://openalex.org/C519581460', 'wikidata': 'https://www.wikidata.org/wiki/Q207843', 'display_name': 'Nitric oxide', 'level': 2, 'score': 0.49495214}, {'id': 'https://openalex.org/C17991360', 'wikidata': 'https://www.wikidata.org/wiki/Q21173843', 'display_name': 'Tumor necrosis factor alpha', 'level': 2, 'score': 0.48934335}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4772684}, {'id': 'https://openalex.org/C125473707', 'wikidata': 'https://www.wikidata.org/wiki/Q9914', 'display_name': 'H&E stain', 'level': 3, 'score': 0.46801388}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.44549844}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.41936672}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.33242956}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.2527879}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.11711112}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.09784934}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN32176120133409/368753.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764984328', 'display_name': 'Guoji mazuixue yu fusu zazhi', 'issn_l': '1673-4378', 'issn': ['1673-4378'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032656063', 'https://openalex.org/W3030762617', 'https://openalex.org/W3030759614', 'https://openalex.org/W3029933832', 'https://openalex.org/W3029430980', 'https://openalex.org/W3029378453', 'https://openalex.org/W3028904601', 'https://openalex.org/W2461997138', 'https://openalex.org/W2386982324', 'https://openalex.org/W2379061262', 'https://openalex.org/W2377073190', 'https://openalex.org/W2376509517', 'https://openalex.org/W2371448156', 'https://openalex.org/W2367292031', 'https://openalex.org/W2363668279', 'https://openalex.org/W2359340327', 'https://openalex.org/W2358706576', 'https://openalex.org/W2354842328', 'https://openalex.org/W2352617254', 'https://openalex.org/W2349779310'], 'abstract_inverted_index': {'Objective': [0], 'To': [1], 'investigate': [2], 'the': [3, 60, 86], 'protective': [4, 240], 'effects': [5, 241], 'of': [6, 66, 108, 130, 226], 'sodium': [7], 'butyrate': [8, 238, 258, 273], 'on': [9], 'acute': [10], 'lung': [11, 102, 142, 155, 176, 252, 270], 'injury': [12, 157], '(ALI)': [13], 'induced': [14, 153], 'by': [15, 98, 147, 232, 242], 'lipopolysaccharide': [16], '(LPS)': [17], 'in': [18, 80, 141, 162, 175, 204], 'rats.Methods': [19], 'Totally': [20], 'forty': [21], 'male': [22], 'SD': [23], 'rats': [24, 40], 'were': [25, 41, 54, 83, 88, 96, 106, 145, 229], 'randomly': [26], 'divided': [27], 'into': [28], 'control': [29, 36], 'group,SB': [30], 'group,LPS': [31], 'group': [32, 53, 62, 82, 123], 'and': [33, 37, 48, 73, 101, 113, 116, 118, 120, 128, 134, 138, 158, 165, 172, 198, 246, 255, 264], 'SB+LPS': [34, 61], 'group.In': [35], 'SB': [38, 49, 67, 235], 'group,the': [39], 'given': [42], 'normal': [43], 'saline': [44], '(2': [45], 'ml/kg)': [46], 'intravenously': [47], '(500': [50, 68], 'mg/kg)intraperitoneally.The': [51], 'LPS': [52, 56, 77, 152, 196], 'injected': [55], '(6': [57], 'mg/kg)': [58, 69], 'intravenously,while': [59], 'received': [63], 'intraperitoneally': [64], 'injection': [65], 'at': [70], '0': [71], 'h': [72, 75], '4': [74], 'after': [76, 85], 'administration.The': [78], 'animals': [79], 'each': [81], 'sacrificed': [84], 'models': [87], 'completed': [89], 'successfully': [90], 'for': [91], 'six': [92], 'hours.Pulmonary': [93], 'histological': [94, 156], 'changes': [95, 228], 'evaluated': [97], 'hematoxylin-eosin': [99], 'stain': [100], 'wet/dry': [103], 'weight': [104], 'ratios': [105], 'observed.Concentrations': [107], 'tumor': [109], 'necrosis': [110], 'factor': [111], '(TNF-α)': [112], 'interleukin': [114], '(IL)-1β': [115], 'IL-8': [117], 'IL-10': [119, 219], 'high': [121], 'mobility': [122], 'box': [124], '1': [125], '(HMGB-1)in': [126], 'plasma': [127], 'concentrations': [129], 'nitric': [131], 'oxide': [132], '(NO)': [133], 'myeloperoxidase': [135], '(MPO)': [136], 'activity': [137, 167], 'malonaldehyde': [139], '(MDA)': [140], 'tissue': [143, 177], 'homogenates': [144, 178], 'measured': [146], 'enzyme-linked': [148], 'immunosorbent': [149], 'assay': [150], '(ELISA).Results': [151], 'marked': [154], 'a': [159, 201, 221], 'significant': [160], 'increase': [161], 'W/D': [163], 'ratio': [164], 'MPO': [166], 'as': [168, 170, 249, 251], 'well': [169, 250], 'MDA': [171], 'NO': [173], 'levels': [174], '(4.48': [179], '±0.23)': [180], 'vs': [181, 188], '(4.20': [182], '±0.11),(0.84': [183], '±0.05)vs': [184], '(0.68': [185], '±0.03),(5.75': [186], '±0.19)': [187], '(2.74': [189], '±0.20),(41': [190], '±4)vs': [191], '(33': [192], '±7)': [193], '(P＜0.01).Compared': [194], 'with': [195, 234], 'group,TNF-α,IL-1β,IL-8': [197], 'HMGB-1': [199], 'showed': [200, 220], 'decreasing': [202], 'trend': [203, 223], 'LPS+SB': [205], 'group(2350.23±120.76)vs': [206], '(1150.45': [207], '±153.78),(395.13': [208], '±20.39)vs': [209], '(202.69': [210], '±18.21),(89.34': [211], '±7.32)vs': [212], '(49.65': [213], '±5.09),(115.28': [214], '±12.37)vs': [215], '(62.18': [216], '±15.89)': [217], '(P＜0.05),while': [218], 'rising': [222], '(281.23±24.56)vs(100.78±14.47)(P＜0.05).However': [224], 'all': [225], 'these': [227], 'significantly': [230], 'attenuated': [231, 261], 'posttreatment': [233], '(P＜0.05).Conclusions': [236], 'Sodium': [237, 272], 'exert': [239], 'inhibiting': [243], 'neutrophil': [244], 'aggregation': [245], 'cytokine': [247], 'production': [248], 'lipid': [253], 'peroxidation': [254], 'nitro': [256], 'effect.Sodium': [257], 'can': [259], 'also': [260], 'pulmonary': [262], 'edema': [263], 'cell': [265], 'damage.\r\n\r\nKey': [266], 'words:': [267], '\r\nLipopolysaccharide;\xa0': [268], 'Acute': [269], 'injury;\xa0': [271]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031106749', 'counts_by_year': [], 'updated_date': '2024-12-15T21:06:53.453910', 'created_date': '2020-06-05'}