Title: Assessment of left ventricular volume and function in patients with left ventricular non-compaction by contrast-enhanced three-dimensional echocardiography
Abstract: Objective To evaluate the value of echo-contrast RT-3DE for assessment of left ventricular volume and function in patients with left ventricular non-compaction(LVNC).Methods Twenty- one patients of LVNC were involved and underwent non-enhanced and contrast-enhanced RT-3DE to evaluate left ventricular end-diastolic volume (LVEDV),left ventricular end-systolic volume (LVESV),left ventricular ejection fraction (LVEF).The endoeardial border definition of LV was graded for each of the 16 LV segments as follows: 0 = border invisible, 1 = border visualized only partially, and 2 = complete visualization of the border. Three image-quality groups (good, fair, and uninterpretable) were identified. Results ① During contrast-enhanced RT-3DE, as compared with non-enhanced RT-3DE, the number of segments with complete visualization of the endocardial border increased significantly (55 % vs 82%, P〈 0.01), and the number of patients with a good-quality echocardiogram increased significantly (33 % vs 81 %, P 〈0.01).②Contrast-enhanced RT-3DE provided significantly larger values of LVEDV ( P 〈0.01) and LVESV ( P 〈0.01) as compared with non-enhanced RT-3DE, the values of LVEF were not statistically different between the two techniques ( P = 0.07).③Intra- and inter-observer agreement for assessment of LV volumes and systolic function improved during contrast-enhanced RT-3DE, as compared with non- enhanced RT-3DE. Conclusions Contrast-enhanced RT-3DE can increase the prevalence of good-quality echocardiograms and significantly improve the reproducibility of LV volumes and function measurements.
Key words:
Echocardiography, real-time three-dimensional; Microbubbles; Noncompaction ofventricular myocardium ; Ventricular function,left
Publication Year: 2014
Publication Date: 2014-11-25
Language: en
Type: article
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Cited By Count: 1
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