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'https://openalex.org/W2749629887', 'https://openalex.org/W2467784178', 'https://openalex.org/W2384547203', 'https://openalex.org/W2368386984', 'https://openalex.org/W2362633077', 'https://openalex.org/W2348638534', 'https://openalex.org/W2317124209', 'https://openalex.org/W2211023739', 'https://openalex.org/W2104334881', 'https://openalex.org/W2065888977', 'https://openalex.org/W2056527928', 'https://openalex.org/W1967725568'], 'abstract_inverted_index': {'目的': [0], '探讨125I粒子持续低剂量率照射诱导人前列腺癌细胞凋亡的作用机制.方法': [1], '用DNA琼脂糖凝胶电泳和流式细胞仪分析125I粒子持续低剂量率照射对PC3细胞的凋亡诱导作用,检测天冬酰胺特异酶切的半胱氨酸蛋白酶Caspase-3活性来观察其对PC3细胞的凋亡诱导途径,并通过间接免疫荧光技术检测其对Bcl-2表达的影响.结果': [2], 'DNA琼脂糖凝胶电泳可观察到清晰的DNA梯度,流式细胞仪检测125I粒子持续低剂量率照射对PC3细胞具有明显的凋亡诱导作用.Caspase-3活性检测表明,Caspase-3活性无明显变化.流式细胞仪分析表明Bcl-2的表达随125I粒子剂量的增加而下降.结论': [3], '125I粒子持续低剂量率照射可诱导PC3细胞凋亡,其诱导凋亡与Bcl-2表达有关,与Caspase-3活性无关。': [4]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030752136', 'counts_by_year': [], 'updated_date': '2024-08-21T22:14:38.244439', 'created_date': '2020-06-05'}