Title: Treatment of infections in patients with primary immunodeficiency disease
Abstract: Primary immunodeficiency disease (PID) is a heterogeneous group of congenital disorders of the immune system.The impaired immune response is caused by defect of immune active cells and moleculars,which results in increased susceptibility to pathogens.Recurrent infection is the predominant presenting complaint for patients with PID.Early diagnosis,immunoglobulin replacement therapy,antimicrobial treatment,haematopoietic stem cell transplantation and gene therapy,genetic conselling and prenatal diagnosis will help to prevent and control infections in patients with PID.In addition,we should strengthen the education of paediatricians,improve awareness about PID and collaboration across different centers to advance the diagnosis and management of PID in China and save the life of patients at the maximum limit.
Key words:
Primary immunodeficiency diseases; Infection; Replacement treatment; Haematopoietic stem cell transplantation; Gene therapy
Publication Year: 2013
Publication Date: 2013-06-20
Language: en
Type: article
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