Title: Kidney transplantation from donation after citizens death of 233 cases: one single center experience
Abstract: Objective To explore the clinical effect and improvement measure of kidney transplantation from donation after citizens death in our center.Methods The data of 233 cases of kidney transplantation from 130 citizens death donors from February 2007 to August 2013 in our centre were retrospectively reviewed.Graft function recovery and rejection rate,patient/kidney survival rate and complications,effect of kidney transplantation about pediatric donors and pediatric recipients were analyzed.Results Seventy-seven citizens death donors in our hospital and 53 from other organ procurement organization successfully donated their organs.The recipients were followed up for 1 month to 6 years.The 6-month,and 1-,3-,5-year patient/graft survival rates were 99.1%/95.7%,99.1%/95.7%,99.1%/94.5% and 98.7%/ 93.3%.Primary non-function occurred in 2 recipients (0.8%),delayed graft function (DGF) occurred in 33 recipients (14.2%).Three recipients died with the graft function.There were 6 cases of nephrectomy and 28 cases with pulmonary infection.Fifty patients received pediatric kidney allografts; ten were pediatric recipients and 40 were adults.Acute humoral rejection occurred in 1 adult recipient and acute cellular rejections occurred in 3 recipients.All the 4 patients were reversed after anti-rejection therapy.Six cases of en bloc kidney transplantations were performed,including 2 cases of thrombosis in one renal artery after transplantation.Twenty-one pediatric recipients underwent kidney transplant,including 11 kidneys from adult donors and 10 from pediatric donors.DGF occurred in 2 patients after transplant.Conclusions Well shortterm and medium-term outcomes can be achieved in kidney transplant from donation after citizens death by using a variety of measures to recover the kidneys.Rational using of pediatric donation organ could result in excellent outcome of transplantation.The policy of organ allocation and sharing for organ from donation after citizens death could contribute to the development of pediatric renal transplantation.
Key words:
Donation after citizens death ; Kidney transplantation ; Pediatric donor ; Pediatric recipient
Publication Year: 2014
Publication Date: 2014-01-15
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot