Title: Research progress on relationship between receptor tyrosine kinase c-Met and lung cancer
Abstract: Receptor tyrosine kinase c-Met is encoded by c-Met proto-oncogene. It plays an important role in cell growth,invasion,anti-apoptosis,and other biological effects. The abnormal expression of c-Met is closely related with the development and malignant biological behaviour of lung cancer. The targeted therapy for c-Met pathway is the new hot spot of lung cancer treatment. This paper reviews biological characteristics of receptor tyrosine kinase c-Met,its relationship with lung cancer,and the application in treatment of lung cancer.
Key words:
Proto-oncogene; Mutation; Lung cancer; Receptor ; Targeted therapy
Publication Year: 2011
Publication Date: 2011-05-20
Language: en
Type: article
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