Title: Use of bipolar radiofrequency device Habib 4X in hepatic malignant tumor resection
Abstract: Objective
To assess the use of bipolar radiofrequency device Habib 4X in hepatic malignant tumor resection.
Methods
Clinical data of 75 patients with hepatic malignant tumor undergoing hepatectomy with the use of Habib 4X in Department of Gastrointestinal Oncology, Cancer Center of Guangzhou Medical University from February 2009 to June 2013 were retrospectively analyzed. There were 55 males and 20 females with a mean age of (53±12) years old. Forty-nine cases were with primary liver cancer and 26 cases were with secondary liver cancer. The informed consents of all patients were obtained and the ethics committee approval was received. Patients received endotracheal general anesthesia. Hepatectomy was performed after tumor ablation was employed with Habib 4X device 2-3 cm away from the tumor. The intraoperative bleeding, blood transfusion, operation duration, changes of postoperative alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TB), length of postoperative hospital stay and complications were observed. Patients were followed up after being discharged from hospital and tumor recurrence and mortality were observed.
Results
All the 75 patients underwent hepatectomy successfully. The mean intraoperative bleeding was (318±89)ml, the rate of blood transfusion was 7% (5/75), the median of operation duration was 104 (17-191) min, the length of postoperative hospital stay was (11±4)d. ALT, AST, TB rose to a top level 1 d after operation, then went down progressively and liver function backed to normal 9 d after operation. Two cases suffered from bile fistula and were cured after enhancing drainage. The 1-, 3-year recurrence rates were 6% (3/49), 10% (5/49) respectively in patients with primary liver cancer and were 23% (6/26), 27% (7/26) respectively in patients with secondary liver cancer. The mortality were 4% (2/49), 27% (7/26) respectively in patients with primary liver cancer and secondary liver cancer during the follow-up. Two cases with primary liver cancer died of postoperative hepatic encephalopathy and 7 cases with secondary liver cancer died of tumor widespread metastasis.
Conclusions
Habib 4X is safe and effective for hepatic malignant tumor resection. It may reduce the postoperative tumor recurrence rate.
Key words:
Liver neoplasms; Hepatectomy; Habib 4X; Blood loss, surgical; Neoplasm recurrence, local
Publication Year: 2014
Publication Date: 2014-04-10
Language: en
Type: article
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