Title: Clinical significance of IQQA-Liver in the evaluation of liver volume and hepatic vein territory before live donor liver transplantation with a right lobe graft
Abstract: Objective
To investigate the clinical significance of an IQQA-Liver three dimensional system in the evaluation of hepatic volume and hepatic venous drainage territory before live donor liver transplantation (LDLT) with a right lobe graft.
Methods
The total hepatic volume and right hemihepatic volume of 92 donors were determined with IQQA semiautomatic method (IQQAVtotal and IQQAV) and traditional CT manual method (CTVtotal and CTV) . Right portal vein territorial volume (RPVTV) of 92 donors were determined, and efficient functional hepatic volume (EFHV) were obtained by simulating hepatic section and venous reconstruction schedule. The preoperative right hemihepatic volume obtained via four methods were compared with the intraoperative volume (IOV) in LDLT and then evaluated through paired t test and correlation analysis between interclass data. P≤0.05 was considered statistically significant. The relationship of the diameter and the territorial volume of 254 hepatic vein were analyzed.
Results
The correlation coefficients were 0.96 for CTVtotal and IQQAVtotal and 0.93 for CTV and IQQAV. The correlation coefficients were 0.82, 0.81, 0.77, and 0.81 for IQQAV, CTV, RPVTV, EFHV, and IOV, respectively. The correlation coefficient was 0.73 between the diameter and territorial volume of the hepatic vein (P≤0.01) .
Conclusions
The hemihepatic volume obtained through IQQA-Liver was associated with IOV. However, the diameter of the tributaries of the hepatic vein cannot completely represent homologous territorial volume. EFHV should be calculated to evaluate a patient′s status before operation is performed.
Key words:
Liver transplantation; Volume; Hepatic venous drainage territory; Graft-to-recipient body weight ratio
Publication Year: 2016
Publication Date: 2016-07-25
Language: en
Type: article
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