Title: Metastatic characteristics of lymph node in cervical region and radiotherapy target volume after dissection of thoracic esophageal carcinoma
Abstract: Objective To investigate the metastatic characterislics of cervical lymph node in thoracic esophageal cancer of two-field lymph node dissection after radical surgery and to provide evidence for postoperative radiotherapy. Methods Local-regional lymph node metastasis after surgery of 126 cases with esophageal squamous cell carcinoma from 2004 t0 2009 were reviewed. Boundaries of cervical lymph node were according to Som,s imaging-based nodal classification system. Enumeration data were compared by X2 test , and the risk factors of lymph node metastasis were analyzed with Logistic regressive model . Results Lymph node metastasis rate of cervical region was up t0 68. 3% in all the cases with local-regional lymph node metastasis (86/126) , and lymph node metastasis rate in level I was higher than those in the other levels (43. 7% , 55/126) . There was obvious difference in lymph node metastasis rate between the right and the left cervical region (53. 2% vs 30. 2% ,X2 = 13. 73 ,P = 0. 000). Moreover, the results also shown that lymph node metastasis rate was notably increased in levelⅠ ,Ⅱ and Ⅲa of the right compared with those of the left, showing statistical significance ( 43. 70% : 15. 1% , 17. 5% : 7. 1 % , 17. 5% : 5. 6% , X2 = 24. 79,6. 22,8. 77 ,P =0. 000 ,0. 013 ,0. 003) . The sum of lymph node metastasis rate was 95% ( 82/86) in pararecurrent nerve and medial jugular vein, and 85% ( 73/86) in para-recurrent nerve. In addition,multivariate analysis showed that lymph node metastasis in level Ⅰ was high risk factor for lymph nodemetastasis of level Ⅱ . Conclusions Lymph node metastasis of cervical region mainly focused on pararecurrent nerve and medial jugular vein.
Key words:
Esophageal neoplasms/surgery; Neoplasms metastasis,neck lymph node; Radiotherapy target volume
Publication Year: 2012
Publication Date: 2012-03-15
Language: en
Type: article
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Cited By Count: 1
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