Title: [Applicability of methods for determination of iodine in nutrition formula].
Abstract: The applicability of both inductively coupled plasma mass spectrometry( ICP-MS) and gas chromatography( GC) method to accurately determine iodine in dairy products with different matrices was assessed.The performance of ICP-MS iodine method for dairy products has been validated by assessing its linearity, precision, accuracy, limit of detection( LOD) and limit of quantity( LOQ) in various food matrices. Both GC and ICP-MS method were used to determine iodine in samples with 7 different types of matrices, including milk base formula, low lactose formula, partially hydrolyzed protein formula, soy protein contained formula, high protein formula, deeply hydrolyzed protein formula and complete nutrition formula( mixed protein sources). The testing result were compared, and the root cause of the result difference between the two method was further investigated and discussed.The ICP-MSmethod showed a good precision and accuracy in different types of dairy products. The experiments demonstrated that the result differences were less than 11% between two method in milk base formula. The GC result were typically 10%-20% lower than the ICP-MS result in most foods for special medical purpose( FSMP) products. One extreme case occurred in the complete nutrition formula sample, in which the GC result was71. 1% lower than the ICP-MS result. By testing the iodine distribution by ICP-MS after each step of sample preparation of the GC method, most iodine in this formula has been removed during the protein precipitation step, causing the extremely low iodine recovery.ICP-MS method is more robust and has larger applicable scope, which is more suitable for the routine test of iodine in FSMP products.
Publication Year: 2018
Publication Date: 2018-11-01
Language: en
Type: article
Indexed In: ['pubmed']
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