Abstract: Prion diseases are fatal neurodegenerative disorders that lead to spongiform degeneration of the brain and the deposition of abnormally conformed host-derived prion protein. Up to 15% of the cases are autosomal genetic and caused by multiple mutations in PRNP. Inheritance is autosomal dominant.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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Cited By Count: 1
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